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- Creators: Barrett, The Honors College
Description
It is possible that voluntary studies on the effects of divorce fail to capture the perspectives of offspring who may be deterred from volunteering by their negative experiences of the divorce of their parents. This issue of non-response bias would cause researchers to gather unrepresentative samples that ultimately create an unrepresentative picture on the effects of divorce. The problem of non-response bias may also be a possible explanation for why research shows that small differences in psychological problems exist between children of divorce and children from intact families. This study sought to identify if non-response bias compromises the external validity of a sample of college students of divorce. To answer this question we conducted this study through the use of the introductory psychology pre screening study that is administered every semester to introductory psychology students at Arizona State University. We surveyed undergraduate introductory psychology students, all of whom completed a required prescreen survey for research credit. The students who indicated they were from divorced families, or whose parents were “never married and not still together”, were invited to participate in a follow up study to “to understand young adults’ perspectives on their parents’ divorce”. The students who responded to our invitation were compared to the students who did not volunteer in terms of their prescreen data. Volunteers did not differ from non-volunteers on seven out of the ten dependent measures. Volunteers differed from non-volunteers in terms of their closeness to their fathers, in terms of the parents conflict they experienced during the two years before and the two years after their parents permanently separated. Volunteers were more likely to be closer to their fathers and more likely to have experienced more parent conflict than non-volunteers. We are unaware of any studies on the subject of divorce that have had a similar opportunity to address the issue of non-response bias and its effects on the external validity of a college sample of divorce. This study should be replicated to determine the reliability of the results.
ContributorsRussell, Megan Magdalena (Author) / Fabricius, William (Thesis director) / Doane, Leah (Committee member) / Pina, Armando (Committee member) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The purpose of this study is to examine the baseline level of structural competency present in the general public and determine whether or not an individual’s demographics meaningfully affect this knowledge. This aim was accomplished by analyzing observational data from a citizen social science (CSS) project. Undergraduate students enrolled in the “Urban and Environmental Health” course described in Ruth et al. (2020) trained and recruited 165 CSS to record observations of fixed exclusions of women, minorities/Latinx, and large bodied people in the built environment. Participants walked along nine distinct transects in downtown Tempe, Arizona and recorded their observations. Of the 165 initial participants, 134 satisfactorily completed the task and were included in the statistical analysis. The observations of each CSS were scored against a gold standard, yielding a percent of observations observed for each exclusion category. Statistical analysis using Aligned Rank Transform (ART) Factorial ANOVA and Mann-Whitney U Tests were then employed to test for differences in the number of observations across demographic categories and subcategories. Among the main demographic factors, ethnicity produced a statistically significant difference in observations, but only for gendered exclusions. For the demographic subcategories, the only significant difference was observed in men, where ethnicity and body size both showed an effect on observations of women and ethnicity respectively. Due to the large similarity in observations across demographic categories, any interventions aimed at increasing the structural competency of a population need not target specific groups, but rather the population as a whole.
ContributorsMcguire, Collin James (Author) / Ruth, Alissa (Thesis director) / SturtzSreetharan, Cindi (Committee member) / School of Molecular Sciences (Contributor) / School of Human Evolution & Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
This paper focuses on our research of analyzing the implementation of AHCCCS's Targeted Investment Program at Children's Rehabilitative Services. Our main focus throughout the paper is analyzing the specific steps and requirements it took to implement this program successfully. By analyzing these steps, we developed complexities and enablers it took for the clinic to implement this program.
ContributorsTodd, Hannah (Co-author) / Seeger, Lily (Co-author) / Hall, Rick (Thesis director) / O'Brien, Janet (Committee member) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Ethnic, Familial, and Cultural Barriers Impacting non-White Representation in Environmental Programs
Description
Non-White minorities represent nearly half of the US population and strongly support environmental protection but are severely underrepresented in environmental careers and natural resource-related degree programs. What factors contribute to this disparity in environment career choice? Previous research has indicated that students career decisions are influenced by family and culture as they related to self-efficacy beliefs and outcome expectations towards different occupation choices. In this paper, I explored the importance of familial and cultural factors in career choice decisions to understand the motivations of non-White minority students to enter and remain in college degree programs within environmental disciplines. I surveyed 122 students enrolled in both environmental and non-environmental degree programs at Arizona State University. I measured family and cultural influence using the “Family Influence Scale” and “Orthogonal Cultural Identification Scale” respectively. I hypothesized that non-White students in environmental degree programs are influenced less by their families and are more acculturated to the dominant Anglo culture compared to non-White students in non-environmental degree programs. I found no significant relationship between ethnicity, family influence, or acculturation on the degree choices of students. Interestingly, family influence on students’ career decisions was most influenced by home language, household income, and acculturation to the dominant culture. Students more acculturated to Anglo culture reported higher familial influence. Higher income and non-English speaking households also reported higher levels of family influence. Acculturation and language in particular are interesting factors related to family influence and warrant further analysis especially in relation to non-White student participation in environmental careers.
ContributorsGutierrez, Luis (Co-author, Co-author) / Hall, Sharon (Thesis director) / Budruk, Megha (Thesis director) / Salgado, Casandra (Committee member) / School of International Letters and Cultures (Contributor) / Division of Teacher Preparation (Contributor) / School of Life Sciences (Contributor, Contributor) / School of Sustainability (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
In examining the popular culture of the United States today, one would find themselves hard-pressed to avoid mentions of texts and films that fall within the fantasy genre. In fact, many works within this genre find themselves amongst the ranks of the best-selling books and movies of all time (Moor; Harding and Thompson). Outside of their economic success, these stories have become an integral part of American culture. Extending from the domination of the entertainment industry, the characters and stories of the fantasy genre have influenced the collective ideals and perspectives of the United States population. Websites such as DeviantArt and Archive of Our Own serve as testament to how these stories inspire their fans, boasting thousands of pieces of artwork and writing that have been inspired by various fantasy texts and films. Beyond this, characters featured in these stories find themselves being applied elsewhere, ranging from their prevalence in online meme culture to their use during times of political strife. A notable example of this is a photograph of a protestor holding up a large sign boasting the claim that “Dumbledore wouldn’t let this happen,” which later became viral and was posted across several media platforms (whiskey-tango). The importance and impact of the fantasy genre can clearly be seen to take on many forms, and can be observed as playing a larger role than simple entertainment in the lives of the American public. While all of these examples highlight the deeply embedded nature of these tales in popular culture, it begs the question as to how and why these stories got to this status.
ContributorsKrolick, Samantha Rae (Author) / Cruse, Markus (Thesis director) / Fong, Benjamin (Committee member) / School of Life Sciences (Contributor) / Dean, The College of Liberal Arts and Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The purpose of this study was to determine current feelings of veterinary staff on their relation to the topics of burnout and compassion fatigue in their field. Additionally, this study was used to determine possible solutions to these mental health issues facing veterinary staff, with solutions coming straight from staff members themselves. Burnout, often experienced by healthcare workers, is a “state of physical or emotional exhaustion that also involves a sense of reduced accomplishment and loss of personal identity” (Mayo Clinic 2018). Compassion fatigue is a loss of empathy to stressful or emotionally draining situations mostly due to frequent encounter with these situations. Using a survey conducted on veterinary professionals, opinions on attitudes toward work environments as well as thoughts on potential solutions to issues with burnout and compassion fatigue were analyzed. Survey respondents ranged from technicians and support staff to doctors and DVM (Doctor of Veterinary Medicine) students. Results of the survey showed that DVM students were under increased pressure, many respondents often felt tired before arriving to work, and doctors felt they did not perform their jobs with the same enthusiasm as when they first started in the field. However, many respondents indicated they were happy and invigorated by accomplishments in the workplace. The respondent comments also displayed a wide range of possible solutions to these mental health issues. Understanding the root causes of these issues as well as possible solutions to help alleviate them could help prevent harsh consequences such as suicide from occurring.
ContributorsOrcutt, Julia Clare (Author) / DeNardo, Dr. Dale (Thesis director) / Thatcher, Dr. Craig (Committee member) / Usiak-Mcbeth, Dr. Megan (Committee member) / School of Sustainability (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
In this thesis, I attempted to analyze different rebrands that proved to be either successful or unsuccessful. As case studies, I looked into Old Spice and Sprite, the successful rebrands, and Tropicana, the unsuccessful one. From there, I attempted to breakdown and provide an analysis of similarities and differences of the factors affecting the successful rebrands, as well as between the successful and unsuccessful rebrands. This included key aspects such as the effects of competition as well as what external and internal conditions affected the result of the rebrand.
Additionally, I provided a self-made framework that analyzes several factors that make up the market which companies should research and be aware of. This framework breaks down into both external, how market, customer, and competitive factors lend themselves to a rebrand as well as internal, how the rebrand will address the market and how the brand image will be changed by the rebranding.
Additionally, I provided a self-made framework that analyzes several factors that make up the market which companies should research and be aware of. This framework breaks down into both external, how market, customer, and competitive factors lend themselves to a rebrand as well as internal, how the rebrand will address the market and how the brand image will be changed by the rebranding.
ContributorsWright, Hunter (Author) / Riker, Elise (Thesis director) / Bonfiglio, Thomas (Committee member) / Department of Marketing (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The epidemic of drug addiction continues to grow at an alarming rate and cocaine-related overdoses have increased by more than 33% over the last decade. Cocaine targets the mesolimbic reward system in the brain to produce the “high” felt when taking cocaine. There is currently no single cure for psychostimulant abuse, but researchers continue to find viable therapeutic options. Dopamine receptors have been a recent target for researchers. We tested a novel D3R-antagonist, SWR-5, with 905-fold D3/D2 selectivity, on addiction using a rat self- administration model and hypothesized that it would reduce motivation for cocaine. SWR-5 significantly reduced cocaine intake on a high-effort PR schedule at a dose of 10 mg/kg but did not affect sucrose intake. Also, SWR-5 did not affect either spontaneous or cocaine-induced locomotion. From our results, we concluded that SWR-5 affects motivation for cocaine, not sucrose, and does not produce adverse locomotor effects. Further research would include taking a behavioral economics approach to determine the cost/benefit ratio of taking the drug, as well as performing cue reinstatement tests to solidify whether SWR-5 plays a role in cocaine-seeking behavior.
ContributorsMokbel, Ayleen Marie Halim (Co-author) / Neisewander, Janet (Thesis director) / Sanabria, Federico (Committee member) / Vannan, Annika (Committee member) / School of International Letters and Cultures (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Impairments to mitochondrial function and metabolism can make neurons vulnerable to stress and degeneration. Several studies have shown that aberrations in the electron transport chain (ETC) and the Krebs cycle are involved in the pathogenesis of Parkinson’s disease (PD). Therefore, targeting these pathways is becoming increasingly important in the discovery of new treatment for neurodegenerative diseases like PD. (−)-epigallocatechin-3-gallate (EGCG), the most common polyphenol found in Green tea, has been shown to exert neuroprotective effects and lower the risk of developing PD. However, the mechanism by which it accomplishes this remains to be elucidated. The purpose of this study was to shed light on these mechanisms by exploring the effects of EGCG against MPP+-induced mitochondrial dysfunction with PC12 cells being used as a PD pathological cell model. The cell viability differences between cells treated with varying combinations of MPP+ and EGCG were measured using a CCK-8 assay. The morphology changes induced by the different treatments were then identified with fluorescence microscopy. Next, a Seahorse assay was carried out to investigate mitochondrial function followed by GC-MS and LC-MS analysis to evaluate mitochondrial metabolism. 13C metabolic flux analysis was then used to trace the metabolic flux of the Krebs cycle. The results of the CCK-8 assay and fluorescence microscopy showed that EGCG helps attenuate the decreased viability of PC12 cells as well as the morphology changes induced by MPP+. The Seahorse and GC-MS assay found that the it also helps prevent impaired mitochondrial respiration caused by MPP+. The impaired mitochondrial respiration manifested as alterations to the Krebs cycle and glycolysis. In addition, 13C metabolic flux analysis revealed significant increases in Krebs cycle activity in MPP+-induced PC12 cells if treated with EGCG beforehand. Moreover, LC-MS showed a distinct metabolite profile for each group and identified 26 potent biomarkers. In conclusion, this study demonstrated that EGCG exerts a neuroprotective effect on PC12 cells and helps maintain mitochondrial metabolic balance in the presence of MPP+.
ContributorsLawrence, Kent Alexander (Author) / Gu, Haiwei (Thesis director) / Lake, Douglas (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The human body’s immune system utilizes many different cell types, signaling proteins, and receptors to thwart an infectious pathogen from an individual. Adaptive immunity, particularly with CD4+ T cell lymphocytes & the MHC II receptor, was the focus of this paper by creating a custom destination vector plasmid, pFLIiP, which would contain a gateway cloning site and the nucleotides encoding the first 85 amino acids of the invariant chain protein upstream to provide a means of high-throughput antigen screening via the MHC II receptor and peptide processing pathway. The plasmid pFLIiP was successfully created and sequence verified. Both GFP and mCherry fluorescent proteins were inserted into pFLIiP via LR Clonase and successfully transfected into K562 cancer cells. Fluorescent activity read of a flow cytometer in conjunction with the differing pKa values of the two different fluorescent proteins suggested the fusion protein was in-frame and pFLIiP was successfully targeting the protein to the endosome.
ContributorsGrade, Dylan Beck (Author) / Anderson, Karen (Thesis director) / Hogue, Ian (Committee member) / Knappenberger, Mark (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05