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Description
Alzheimer's disease (AD) is a neurodegenerative disease that damages the cognitive abilities of a patient. It is critical to diagnose AD early to begin treatment as soon as possible which can be done through biomarkers. One such biomarker is the beta-amyloid (Aβ) peptide which can be quantified using the centiloid

Alzheimer's disease (AD) is a neurodegenerative disease that damages the cognitive abilities of a patient. It is critical to diagnose AD early to begin treatment as soon as possible which can be done through biomarkers. One such biomarker is the beta-amyloid (Aβ) peptide which can be quantified using the centiloid (CL) scale. For identifying the Aβ biomarker, A deep learning model that can model AD progression by predicting the CL value for brain magnetic resonance images (MRIs) is proposed. Brain MRI images can be obtained through the Alzheimer's Disease Neuroimaging Initiative (ADNI) and Open Access Series of Imaging Studies (OASIS) datasets, however a single model cannot perform well on both datasets at once. Thus, A regularization-based continuous learning framework to perform domain adaptation on the previous model is also proposed which captures the latent information about the relationship between Aβ and AD progression within both datasets.
ContributorsTrinh, Matthew Brian (Author) / Wang, Yalin (Thesis advisor) / Liang, Jianming (Committee member) / Su, Yi (Committee member) / Arizona State University (Publisher)
Created2022
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Description
Fingerboard study is an essential component of the college guitar curriculum. A Course on Guitar Fingerboard Melody and Harmony is a method to acquire and integrate fundamental music vocabulary for the guitar performer, interpreter, improvisor, and composer, the end goal being mastery of musical vocabulary to enable artistic freedom and

Fingerboard study is an essential component of the college guitar curriculum. A Course on Guitar Fingerboard Melody and Harmony is a method to acquire and integrate fundamental music vocabulary for the guitar performer, interpreter, improvisor, and composer, the end goal being mastery of musical vocabulary to enable artistic freedom and creative depth. This class design facilitates a solid foundation of fundamental components and provides a framework for further study and integration. It offers a concise yet intense course that consolidates, codifies, explores, and applies scale, interval, and chord vocabulary through interpretive, compositional, and improvisational engagement. This project aspires to contribute to the discipline of guitar, its canon, and its pedagogy. This programmed curriculum offers a comprehensive one-year, two-semester, college-level course on fundamental music vocabulary on the guitar fretboard. Its design facilitates a solid foundation for fundamental musical components, equips the student with a working scale and chord vocabulary, reveals how vocabulary is generated on any fretted instrument, and provides a framework for further study and integration. Semester one facilitates in-depth scale and interval study, while semester two investigates triads and seventh chords, reflecting one, two, three, and four voices textures. Each unit contains lessons, assignments, and integration activities. This document provides both teacher edition, units one through four, and student workbook, units five through eight. Students of A Course on Guitar Fingerboard Melody and Harmony can expect dramatic strides in their understanding of musical vocabulary, its applications, and their abilities to associate and engage in real-time interpretative, compositional, and improvisational contexts. Fingerboard knowledge greatly enhances sight reading skills and enables the interpreter to find fingerings that express the rhythmic, melodic, and harmonic character of any particular musical gesture, and consequently, an entire composition. Guitar composers will be most effective when they know the possibilities and parameters of musical vocabulary on the instrument. Often, the study of vocabulary can inform and expand a composer's sonic palette and conception. For improvisers, fingerboard comprehension allows access to any interval, scale, arpeggio, or voicing the ear desires, regardless of where they happen to find themselves on the instrument in that unique moment.
ContributorsZweig, Phillip (Author) / Kim, Ji Leon (Thesis advisor) / Swartz, Jonathan (Committee member) / Rockmaker, Jody (Committee member) / Arizona State University (Publisher)
Created2022
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Description
The issue of women driving remains to be highly debated in Saudi Arabia. Recent developments on its legalization have sparked conversation and discourse, particularly in social media sites like Twitter. Several hashtags have been used to indicate either support or criticism towards the movement.

Examining Twitter tweets and hashtags, the study

The issue of women driving remains to be highly debated in Saudi Arabia. Recent developments on its legalization have sparked conversation and discourse, particularly in social media sites like Twitter. Several hashtags have been used to indicate either support or criticism towards the movement.

Examining Twitter tweets and hashtags, the study explored how the discourse on women driving had been executed, particularly in between genders. The study analyzed a sizeable number of tweets as well as their context via linguistic corpora analysis. Following Norman Fairclough’s framework, the two opposing perspectives were investigated both at a level of textual analysis. The selected tweets were representative of the three hashtags that emerged on the heat of the discourse regarding the issue of women driving in Saudi Arabia: #Women_car_driving, #I_will_drive_my_car_June15, and #I_will_enter_my_kitchen_June15.

The results showed, among others, that tweets with the hashtag #Women_car_driving presented a tremendous support towards the movement. On the other hand strong opposing reactions emerged from the hashtags #I_will_drive_my_car_June15 and #I_will_enter_my_kitchen_June15.
ContributorsAljarallah, Rayya Sulaiman (Author) / Adams, Karen (Thesis advisor) / Gelderen, Elly van (Committee member) / Prior, Matthew (Committee member) / Arizona State University (Publisher)
Created2017
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Description
A manuscript of a symphony kept on the bookshelves of a library is like a great painting hidden away in a museum where no one can see it. Music needs to be performed to be appreciated and embedded into a culture. The work of a composer must be made accurately

A manuscript of a symphony kept on the bookshelves of a library is like a great painting hidden away in a museum where no one can see it. Music needs to be performed to be appreciated and embedded into a culture. The work of a composer must be made accurately easily accessible to musicians and the public for the work to be widely disseminated. This critical edition marks an effort in this direction to shed light on a major work of Mexican composer José Francisco Vásquez Cano (1896-1961).José F. Vásquez was one of the most prolific Mexican composers and accomplished conductors in the first half of the 20th century, yet there is little widespread knowledge about his life and works. This critical edition of the first movement of Symphony No. 2 (1929) will create a path to further performances and recordings, so that future generations in Mexico and abroad can acquire a wider appreciation of this composer’s role in the wider Mexican cultural heritage. This edition aims to show with transparency every critical decision made based on the score’s manuscript and presently available set of instrumental parts. Due to the continued efforts of José J. Vásquez (the composer’s son) to promote the recovery and performance of his father’s music, I have had access to a black and white scan of the full score’s manuscript, and high-definition color scans of 29 parts for each instrument, allowing me to accurately pinpoint possible errata in the manuscript. The critical commentary along with the digitized score aim to offer future conductors and performers access and insight into this important work by an invaluable composer.
ContributorsHernández Bolaños, Francisco José (Author) / Meyer, Jeffery (Thesis advisor) / Caslor, Jason (Committee member) / Schildkret, David (Committee member) / Wells, Christi Jay (Committee member) / Arizona State University (Publisher)
Created2022
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Description
Nonalcoholic Steatohepatitis (NASH) is a severe form of Nonalcoholic fatty liverdisease, that is caused due to excessive calorie intake, sedentary lifestyle and in the absence of severe alcohol consumption. It is widely prevalent in the United States and in many other developed countries, affecting up to 25 percent of the population. Due to

Nonalcoholic Steatohepatitis (NASH) is a severe form of Nonalcoholic fatty liverdisease, that is caused due to excessive calorie intake, sedentary lifestyle and in the absence of severe alcohol consumption. It is widely prevalent in the United States and in many other developed countries, affecting up to 25 percent of the population. Due to being asymptotic, it usually goes unnoticed and may lead to liver failure if not treated at the right time. Currently, liver biopsy is the gold standard to diagnose NASH, but being an invasive procedure, it comes with it's own complications along with the inconvenience of sampling repeated measurements over a period of time. Hence, noninvasive procedures to assess NASH are urgently required. Magnetic Resonance Elastography (MRE) based Shear Stiffness and Loss Modulus along with Magnetic Resonance Imaging based proton density fat fraction have been successfully combined to predict NASH stages However, their role in the prediction of disease progression still remains to be investigated. This thesis thus looks into combining features from serial MRE observations to develop statistical models to predict NASH progression. It utilizes data from an experiment conducted on male mice to develop progressive and regressive NASH and trains ordinal models, ordered probit regression and ordinal forest on labels generated from a logistic regression model. The models are assessed on histological data collected at the end point of the experiment. The models developed provide a framework to utilize a non-invasive tool to predict NASH disease progression.
ContributorsDeshpande, Eeshan (Author) / Ju, Feng (Thesis advisor) / Wu, Teresa (Committee member) / Yan, Hao (Committee member) / Arizona State University (Publisher)
Created2021
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Description
Advancements to a dual scale Large Eddy Simulation (LES) modeling approach for immiscible turbulent phase interfaces are presented. In the dual scale LES approach, a high resolution auxiliary grid, used to capture a fully resolved interface geometry realization, is linked to an LES grid that solves the filtered Navier-Stokes equations.

Advancements to a dual scale Large Eddy Simulation (LES) modeling approach for immiscible turbulent phase interfaces are presented. In the dual scale LES approach, a high resolution auxiliary grid, used to capture a fully resolved interface geometry realization, is linked to an LES grid that solves the filtered Navier-Stokes equations. Exact closure of the sub-filter interface terms is provided by explicitly filtering the fully resolved quantities from the auxiliary grid. Reconstructing a fully resolved velocity field to advance the phase interface requires modeling several sub-filter effects, including shear and accelerational instabilities and phase change. Two sub-filter models were developed to generate these sub-filter hydrodynamic instabilities: an Orr-Sommerfeld model and a Volume-of-Fluid (VoF) vortex sheet method. The Orr-Sommerfeld sub-filter model was found to be incompatible with the dual scale approach, since it is unable to generate interface rollup and a process to separate filtered and sub-filter scales could not be established. A novel VoF vortex sheet method was therefore proposed, since prior vortex methods have demonstrated interface rollup and following the LES methodology, the vortex sheet strength could be decomposed into its filtered and sub-filter components. In the development of the VoF vortex sheet method, it was tested with a variety of classical hydrodynamic instability problems, compared against prior work and linear theory, and verified using Direct Numerical Simulations (DNS). An LES consistent approach to coupling the VoF vortex sheet with the LES filtered equations is presented and compared against DNS. Finally, a sub-filter phase change model is proposed and assessed in the dual scale LES framework with an evaporating interface subjected to decaying homogeneous isotropic turbulence. Results are compared against DNS and the interplay between surface tension forces and evaporation are discussed.
ContributorsGoodrich, Austin Chase (Author) / Herrmann, Marcus (Thesis advisor) / Dahm, Werner (Committee member) / Kim, Jeonglae (Committee member) / Huang, Huei-Ping (Committee member) / Kostelich, Eric (Committee member) / Arizona State University (Publisher)
Created2023
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Description
The 1973 Supreme Court case Roe v. Wade was a significant event in the story of fetal personhood—the story of whether embryos and fetuses are legal persons. Roe legalized abortion care in the United States (US). However, the story of fetal personhood began long before the 1970s. People have been

The 1973 Supreme Court case Roe v. Wade was a significant event in the story of fetal personhood—the story of whether embryos and fetuses are legal persons. Roe legalized abortion care in the United States (US). However, the story of fetal personhood began long before the 1970s. People have been talking about embryos, fetuses, and their status in science, the law, and society for centuries. I studied the history of fetal personhood in the United States, tracing its origins from Ancient Rome and Medieval England to its first appearance in a US courtroom in 1884 and then to the Supreme Court’s decision in 1973.

But this isn’t a history of events—of names and dates and typical details. This is a history of words. In the twenty-first century, words used to discuss embryos and fetuses are split. Some people use humanizing language like “unborn children” and “human life.” Others use technical words like “embryos” and “fetuses.” I studied what words people used historically. I charted how words moved from science to the public to the law, and how they impacted court rulings on fetal personhood.

The use of certain words nudged courts to grant additional rights to embryos and fetuses. In the 1960s, writers began describing the science of development, using words like “unborn child” and humanizing descriptions to make embryos and fetuses seem like people already born. That helped build an idea of embryos and fetuses as having “life” before birth. When people began asking courts to legalize abortion care in the 1970s, attorneys on the opposite side argued that embryos and fetuses were “human life,” and that that “life” began at conception.

In those cases, “life” was biologically defined as when sperm fertilized egg, but it was on that biological definition “life” that judges improperly rested their legal rulings that embryos and fetuses were “potential human life” states had a duty to protect. It wasn’t legal personhood, but it was a legal status that let states pass laws restricting abortion care and punishing pregnant people for their behavior, trends that threaten people’s lives and autonomy in the twenty-first century.
ContributorsAbboud, Carolina (Author) / Maienschein, Jane (Thesis advisor) / Justice, George (Committee member) / Marchant, Gary (Committee member) / Pyne, Stephen (Committee member) / Arizona State University (Publisher)
Created2020
Description
The Phoenix Zoo, also known as the Arizona Center for Nature Conservation (PZ), is an Association of Zoos and Aquariums (AZA) accredited zoological institution and among largest-nonprofit, privately-owned zoos in the United States (Smith, 2020). Located within Papago Park in Phoenix (Maricopa County), Arizona, adjacent to the Desert Botanical Garden

The Phoenix Zoo, also known as the Arizona Center for Nature Conservation (PZ), is an Association of Zoos and Aquariums (AZA) accredited zoological institution and among largest-nonprofit, privately-owned zoos in the United States (Smith, 2020). Located within Papago Park in Phoenix (Maricopa County), Arizona, adjacent to the Desert Botanical Garden (DES), the two combine to bring environmental awareness to the Phoenix Metropolitan Region. While the DES specializes in botanical presentation, the ACNC focuses on zoological education. Whereas the flora of DES is well known, that of ACNC has yet to be completely documented. Given its role as a center for public engagement and education, documenting and mapping the floristic diversity of the Phoenix Zoo provides updated botanical information and occurrence records, an important component of understanding biodiversity for the Phoenix area. Between the fall of 2017 and the Spring of 2021, the grounds of the ACNC were walked within the 2-mile perimeter and surrounding exterior within Papago Park. Plant specimens and photographs were collected and archived for later identification using various botanical keys. Species names were verified through updated botanical databases such as Tropicos.org and worldfloraonline.org and compiled into a checklist. A total of 706 species have been identified, and of those 548 specimens have been collected as specimen vouchers. Of these, 120 are of taxa known to be native to the Phoenix Salt River Valley. While approximately 79 of those previously listed taxa native to Papago Park were either not found during this study or were extirpated from the grounds of the ACNC during urbanization of the region. There are 586 exotic taxa, some are common cultivars, while others are new to the region. Data for this survey is publicly available on SEINet, a regional network of North America herbaria (https://swbiodiversity.org/seinet/), as georeferenced voucher specimens, human observations, and photographs. Data is also partially duplicated through the iNaturalist platform (iNaturalist.com).
ContributorsBerry, Zachery R (Author) / Makings, Elizabeth (Thesis advisor) / Pigg, Kathleen B (Thesis advisor) / Wojciechowski, Martin F (Committee member) / Arizona State University (Publisher)
Created2021
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Description
This study explores an innovative framework for a self-sustained traffic operations system using vehicle-to-vehicle (V2V) communications alone. The proposed framework is envisioned as the foundation to an alternative or supplemental traffic operation and management system, which could be particularly helpful under abnormal traffic conditions caused by unforeseen disasters and special

This study explores an innovative framework for a self-sustained traffic operations system using vehicle-to-vehicle (V2V) communications alone. The proposed framework is envisioned as the foundation to an alternative or supplemental traffic operation and management system, which could be particularly helpful under abnormal traffic conditions caused by unforeseen disasters and special events. Its two major components, a distributed traffic monitoring and platoon information aggregation system and a platoon-based automated intersection control system, are investigated in this study.



The distributed traffic monitoring and platoon information aggregation system serves as the foundation. Specifically, each equipped vehicle, through the distributed protocols developed, keeps track of the average traffic density and speed within a certain range, flags itself as micro-discontinuity in traffic if appropriate, and cross-checks its flag status with its immediate up- and down-stream vehicles. The micro-discontinuity flags define vehicle groups with similar traffic states, for initiating and terminating traffic information aggregation. The impact of market penetration rate (MPR) is also investigated with a new methodology for performance evaluation under multiple traffic scenarios.

In addition to MPR, the performance of the distributed traffic monitoring and platoon information aggregation system depends on the spatial distribution of equipped vehicles in the road network as well. The latter is affected by traffic dynamics. Traffic signal controls at intersections play a significant role in governing traffic dynamics and will in turn impact the distributed monitoring system. The performance of the monitoring framework is investigated with different g/C ratios under multiple traffic scenarios.

With the distributed traffic monitoring and platoon information aggregation system, platoons can be dynamically identified on the network in real time. This enables a platoon-based automated intersection control system for connected and autonomous vehicles. An exploratory study on such a control system with two control stages are proposed. At Stage I, vehicles of each platoon will synchronize into a target speed through cooperative speed harmonization. Then, a platoon of vehicles with the same speed can be treated as a single vehicle for speed profile planning at Stage II. Its speed profile will be immediately determined given speed profiles of other platoons and the control goal.
ContributorsLi, Peiheng (Author) / Lou, Yingyan (Thesis advisor) / Zhou, Xuesong (Committee member) / Mirchandani, Pitu (Committee member) / Arizona State University (Publisher)
Created2017
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Description
A volunteered geographic information system, e.g., OpenStreetMap (OSM), collects data from volunteers to generate geospatial maps. To keep the map consistent, volunteers are expected to perform the tedious task of updating the underlying geospatial data at regular intervals. Such a map curation step takes time and considerable human effort. In

A volunteered geographic information system, e.g., OpenStreetMap (OSM), collects data from volunteers to generate geospatial maps. To keep the map consistent, volunteers are expected to perform the tedious task of updating the underlying geospatial data at regular intervals. Such a map curation step takes time and considerable human effort. In this thesis, we propose a framework that improves the process of updating geospatial maps by automatically identifying road changes from user-generated GPS traces. Since GPS traces can be sparse and noisy, the proposed framework validates the map changes with the users before propagating them to a publishable version of the map. The proposed framework achieves up to four times faster map matching performance than the state-of-the-art algorithms with only 0.1-0.3% accuracy loss.
ContributorsVementala, Nikhil (Author) / Papotti, Paolo (Thesis advisor) / Sarwat, Mohamed (Thesis advisor) / Kasim, Selçuk Candan (Committee member) / Arizona State University (Publisher)
Created2017