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Description
Concussion, a subset of mild traumatic brain injury (mTBI), has recently been brought to the forefront of the media due to a large lawsuit filed against the National Football League. Concussion resulting from injury varies in severity, duration, and type, based on many characteristics about the individual that research does

Concussion, a subset of mild traumatic brain injury (mTBI), has recently been brought to the forefront of the media due to a large lawsuit filed against the National Football League. Concussion resulting from injury varies in severity, duration, and type, based on many characteristics about the individual that research does not presently understand. Chronic fatigue, poor working memory, impaired self-awareness, and lack of attention to task are symptoms commonly present post-concussion. Currently, there is not a standard method of assessing concussion, nor is there a way to track an individual's recovery, resulting in misguided treatment for better prognosis. The aim of the following study was to determine patient specific higher-order cognitive processing deficits for clinical diagnosis and prognosis of concussion. Six individuals (N=6) were seen during the acute phase of concussion, two of whom were seen subsequently when their symptoms were deemed clinically resolved. Subjective information was collected from both the patient and from neurology testing. Each individual completed a task, in which they were presented with degraded speech, taxing their higher-order cognitive processing. Patient specific behavioral patterns are noted, creating a unique paradigm for mapping subjective and objective data for each patient's strategy to compensate for deficits and understand speech in a difficult listening situation. Keywords: concussion, cognitive processing
ContributorsBerg, Dena (Author) / Liss, Julie M (Committee member) / Azuma, Tamiko (Committee member) / Caviness, John (Committee member) / Arizona State University (Publisher)
Created2013
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Description
The recent spotlight on concussion has illuminated deficits in the current standard of care with regard to addressing acute and persistent cognitive signs and symptoms of mild brain injury. This stems, in part, from the diffuse nature of the injury, which tends not to produce focal cognitive or behavioral deficits

The recent spotlight on concussion has illuminated deficits in the current standard of care with regard to addressing acute and persistent cognitive signs and symptoms of mild brain injury. This stems, in part, from the diffuse nature of the injury, which tends not to produce focal cognitive or behavioral deficits that are easily identified or tracked. Indeed it has been shown that patients with enduring symptoms have difficulty describing their problems; therefore, there is an urgent need for a sensitive measure of brain activity that corresponds with higher order cognitive processing. The development of a neurophysiological metric that maps to clinical resolution would inform decisions about diagnosis and prognosis, including the need for clinical intervention to address cognitive deficits. The literature suggests the need for assessment of concussion under cognitively demanding tasks. Here, a joint behavioral- high-density electroencephalography (EEG) paradigm was employed. This allows for the examination of cortical activity patterns during speech comprehension at various levels of degradation in a sentence verification task, imposing the need for higher-order cognitive processes. Eight participants with concussion listened to true-false sentences produced with either moderately to highly intelligible noise-vocoders. Behavioral data were simultaneously collected. The analysis of cortical activation patterns included 1) the examination of event-related potentials, including latency and source localization, and 2) measures of frequency spectra and associated power. Individual performance patterns were assessed during acute injury and a return visit several months following injury. Results demonstrate a combination of task-related electrophysiology measures correspond to changes in task performance during the course of recovery. Further, a discriminant function analysis suggests EEG measures are more sensitive than behavioral measures in distinguishing between individuals with concussion and healthy controls at both injury and recovery, suggesting the robustness of neurophysiological measures during a cognitively demanding task to both injury and persisting pathophysiology.
ContributorsUtianski, Rene (Author) / Liss, Julie M (Thesis advisor) / Berisha, Visar (Committee member) / Caviness, John N (Committee member) / Dorman, Michael (Committee member) / Arizona State University (Publisher)
Created2014
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Description
Much evidence has shown that first language (L1) plays an important role in the formation of L2 phonological system during second language (L2) learning process. This combines with the fact that different L1s have distinct phonological patterns to indicate the diverse L2 speech learning outcomes for speakers from different L1

Much evidence has shown that first language (L1) plays an important role in the formation of L2 phonological system during second language (L2) learning process. This combines with the fact that different L1s have distinct phonological patterns to indicate the diverse L2 speech learning outcomes for speakers from different L1 backgrounds. This dissertation hypothesizes that phonological distances between accented speech and speakers' L1 speech are also correlated with perceived accentedness, and the correlations are negative for some phonological properties. Moreover, contrastive phonological distinctions between L1s and L2 will manifest themselves in the accented speech produced by speaker from these L1s. To test the hypotheses, this study comes up with a computational model to analyze the accented speech properties in both segmental (short-term speech measurements on short-segment or phoneme level) and suprasegmental (long-term speech measurements on word, long-segment, or sentence level) feature space. The benefit of using a computational model is that it enables quantitative analysis of L1's effect on accent in terms of different phonological properties. The core parts of this computational model are feature extraction schemes to extract pronunciation and prosody representation of accented speech based on existing techniques in speech processing field. Correlation analysis on both segmental and suprasegmental feature space is conducted to look into the relationship between acoustic measurements related to L1s and perceived accentedness across several L1s. Multiple regression analysis is employed to investigate how the L1's effect impacts the perception of foreign accent, and how accented speech produced by speakers from different L1s behaves distinctly on segmental and suprasegmental feature spaces. Results unveil the potential application of the methodology in this study to provide quantitative analysis of accented speech, and extend current studies in L2 speech learning theory to large scale. Practically, this study further shows that the computational model proposed in this study can benefit automatic accentedness evaluation system by adding features related to speakers' L1s.
ContributorsTu, Ming (Author) / Berisha, Visar (Thesis advisor) / Liss, Julie M (Committee member) / Zhou, Yi (Committee member) / Arizona State University (Publisher)
Created2018