Depressive disorders are common among the general populations but are present at an even higher rate among college students. Some research suggests that new stressors during the transition to college may place young adults at increased risk of depressive disorders. In addition, depression in college students has been linked to a variety of risky behaviors such as alcohol use and risky sexual activity. Fortunately, research suggests that religiosity may act as a buffer and lead to lower levels of depressive symptoms and risky behavior. Current research has not adequately examined the relationship between religiosity, depression, and risky behavior among college students. In this study, depressive symptoms were measured using the 20-item Center for Epidemiological Studies Depression scale, while risky behaviors were measured using the section on risky sexual behavior from the Youth Risk Behavior Surveillance survey and the section on alcohol consumption from the Behavioral Risk Factor Surveillance System survey, both developed by the Centers for Disease Control and Prevention. Four questions frequently used in literature to measure critical behaviors and attitudes were used to assess participants' religiosity. It was predicted that engagement in risky behaviors would be associated with higher levels of depressive symptoms while increased religiosity would be associated with lower levels. Additionally, increased religiosity would be associated with lower levels of engagement in risky behavior. Multiple regression analyses revealed that risky behavior were not significantly associated with higher depressive symptoms, while higher church attendance was associated with lower depressive symptoms. Although not considered a risky behavior, ever being forced to have sex was associated with higher depressive symptoms. Linear regression analyses revealed that increased religiosity was associated with increased engagement in risky behavior. These findings suggest that while depressive symptoms and risky behaviors are prevalent among college students, religiosity may act as a buffer and lead to lower levels of depression and risky behavior. Limitations, implications, and future research are discussed.