Matching Items (4)
Filtering by

Clear all filters

152428-Thumbnail Image.png
Description
Biological organisms are made up of cells containing numerous interconnected biochemical processes. Diseases occur when normal functionality of these processes is disrupted, manifesting as disease symptoms. Thus, understanding these biochemical processes and their interrelationships is a primary task in biomedical research and a prerequisite for activities including diagnosing diseases and

Biological organisms are made up of cells containing numerous interconnected biochemical processes. Diseases occur when normal functionality of these processes is disrupted, manifesting as disease symptoms. Thus, understanding these biochemical processes and their interrelationships is a primary task in biomedical research and a prerequisite for activities including diagnosing diseases and drug development. Scientists studying these interconnected processes have identified various pathways involved in drug metabolism, diseases, and signal transduction, etc. High-throughput technologies, new algorithms and speed improvements over the last decade have resulted in deeper knowledge about biological systems, leading to more refined pathways. Such pathways tend to be large and complex, making it difficult for an individual to remember all aspects. Thus, computer models are needed to represent and analyze them. The refinement activity itself requires reasoning with a pathway model by posing queries against it and comparing the results against the real biological system. Many existing models focus on structural and/or factoid questions, relying on surface-level information. These are generally not the kind of questions that a biologist may ask someone to test their understanding of biological processes. Examples of questions requiring understanding of biological processes are available in introductory college level biology text books. Such questions serve as a model for the question answering system developed in this thesis. Thus, the main goal of this thesis is to develop a system that allows the encoding of knowledge about biological pathways to answer questions demonstrating understanding of the pathways. To that end, a language is developed to specify a pathway and pose questions against it. Some existing tools are modified and used to accomplish this goal. The utility of the framework developed in this thesis is illustrated with applications in the biological domain. Finally, the question answering system is used in real world applications by extracting pathway knowledge from text and answering questions related to drug development.
ContributorsAnwar, Saadat (Author) / Baral, Chitta (Thesis advisor) / Inoue, Katsumi (Committee member) / Chen, Yi (Committee member) / Davulcu, Hasan (Committee member) / Lee, Joohyung (Committee member) / Arizona State University (Publisher)
Created2014
Description
Turing test has been a benchmark scale for measuring the human level intelligence in computers since it was proposed by Alan Turing in 1950. However, for last 60 years, the applications such as ELIZA, PARRY, Cleverbot and Eugene Goostman, that claimed to pass the test. These applications are either based

Turing test has been a benchmark scale for measuring the human level intelligence in computers since it was proposed by Alan Turing in 1950. However, for last 60 years, the applications such as ELIZA, PARRY, Cleverbot and Eugene Goostman, that claimed to pass the test. These applications are either based on tricks to fool humans on a textual chat based test or there has been a disagreement between AI communities on them passing the test. This has led to the school of thought that it might not be the ideal test for predicting the human level intelligence in machines.

Consequently, the Winograd Schema Challenge has been suggested as an alternative to the Turing test. As opposed to deciding the intelligent behavior with the help of chat servers, like it was done in the Turing test, the Winograd Schema Challenge is a question answering test. It consists of sentence and question pairs such that the answer to the question depends on the resolution of a definite pronoun or adjective in the sentence. The answers are fairly intuitive for humans but they are difficult for machines because it requires some sort of background or commonsense knowledge about the sentence.

In this thesis, I propose a novel technique to solve the Winograd Schema Challenge. The technique has three basic modules at its disposal, namely, a Semantic Parser that parses the English text (both sentences and questions) into a formal representation, an Automatic Background Knowledge Extractor that extracts the Background Knowledge pertaining to the given Winograd sentence, and an Answer Set Programming Reasoning Engine that reasons on the given Winograd sentence and the corresponding Background Knowledge. The applicability of the technique is illustrated by solving a subset of Winograd Schema Challenge pertaining to a certain type of Background Knowledge. The technique is evaluated on the subset and a notable accuracy is achieved.
ContributorsSharma, Arpita (Author) / Baral, Chita (Thesis advisor) / Lee, Joohyung (Committee member) / Pon-Barry, Heather (Committee member) / Arizona State University (Publisher)
Created2014
156001-Thumbnail Image.png
Description
The Web is one of the most exciting and dynamic areas of development in today’s technology. However, with such activity, innovation, and ubiquity have come a set of new challenges for digital forensic examiners, making their jobs even more difficult. For examiners to become as effective with evidence from the

The Web is one of the most exciting and dynamic areas of development in today’s technology. However, with such activity, innovation, and ubiquity have come a set of new challenges for digital forensic examiners, making their jobs even more difficult. For examiners to become as effective with evidence from the Web as they currently are with more traditional evidence, they need (1) methods that guide them to know how to approach this new type of evidence and (2) tools that accommodate web environments’ unique characteristics.

In this dissertation, I present my research to alleviate the difficulties forensic examiners currently face with respect to evidence originating from web environments. First, I introduce a framework for web environment forensics, which elaborates on and addresses the key challenges examiners face and outlines a method for how to approach web-based evidence. Next, I describe my work to identify extensions installed on encrypted web thin clients using only a sound understanding of these systems’ inner workings and the metadata of the encrypted files. Finally, I discuss my approach to reconstructing the timeline of events on encrypted web thin clients by using service provider APIs as a proxy for directly analyzing the device. In each of these research areas, I also introduce structured formats that I customized to accommodate the unique features of the evidence sources while also facilitating tool interoperability and information sharing.
ContributorsMabey, Michael Kent (Author) / Ahn, Gail-Joon (Thesis advisor) / Doupe, Adam (Thesis advisor) / Yau, Stephen S. (Committee member) / Lee, Joohyung (Committee member) / Zhao, Ziming (Committee member) / Arizona State University (Publisher)
Created2017
154047-Thumbnail Image.png
Description
Question Answering has been under active research for decades, but it has recently taken the spotlight following IBM Watson's success in Jeopardy! and digital assistants such as Apple's Siri, Google Now, and Microsoft Cortana through every smart-phone and browser. However, most of the research in Question Answering aims at factual

Question Answering has been under active research for decades, but it has recently taken the spotlight following IBM Watson's success in Jeopardy! and digital assistants such as Apple's Siri, Google Now, and Microsoft Cortana through every smart-phone and browser. However, most of the research in Question Answering aims at factual questions rather than deep ones such as ``How'' and ``Why'' questions.

In this dissertation, I suggest a different approach in tackling this problem. We believe that the answers of deep questions need to be formally defined before found.

Because these answers must be defined based on something, it is better to be more structural in natural language text; I define Knowledge Description Graphs (KDGs), a graphical structure containing information about events, entities, and classes. We then propose formulations and algorithms to construct KDGs from a frame-based knowledge base, define the answers of various ``How'' and ``Why'' questions with respect to KDGs, and suggest how to obtain the answers from KDGs using Answer Set Programming. Moreover, I discuss how to derive missing information in constructing KDGs when the knowledge base is under-specified and how to answer many factual question types with respect to the knowledge base.

After having the answers of various questions with respect to a knowledge base, I extend our research to use natural language text in specifying deep questions and knowledge base, generate natural language text from those specification. Toward these goals, I developed NL2KR, a system which helps in translating natural language to formal language. I show NL2KR's use in translating ``How'' and ``Why'' questions, and generating simple natural language sentences from natural language KDG specification. Finally, I discuss applications of the components I developed in Natural Language Understanding.
ContributorsVo, Nguyen Ha (Author) / Baral, Chitta (Thesis advisor) / Lee, Joohyung (Committee member) / VanLehn, Kurt (Committee member) / Tran, Son Cao (Committee member) / Arizona State University (Publisher)
Created2015