Matching Items (3)
Filtering by
- All Subjects: Natural language processing (Computer science)
- Creators: Gonzalez, Graciela
- Creators: Batni, Vaishnavi
Description
Automating aspects of biocuration through biomedical information extraction could significantly impact biomedical research by enabling greater biocuration throughput and improving the feasibility of a wider scope. An important step in biomedical information extraction systems is named entity recognition (NER), where mentions of entities such as proteins and diseases are located within natural-language text and their semantic type is determined. This step is critical for later tasks in an information extraction pipeline, including normalization and relationship extraction. BANNER is a benchmark biomedical NER system using linear-chain conditional random fields and the rich feature set approach. A case study with BANNER locating genes and proteins in biomedical literature is described. The first corpus for disease NER adequate for use as training data is introduced, and employed in a case study of disease NER. The first corpus locating adverse drug reactions (ADRs) in user posts to a health-related social website is also described, and a system to locate and identify ADRs in social media text is created and evaluated. The rich feature set approach to creating NER feature sets is argued to be subject to diminishing returns, implying that additional improvements may require more sophisticated methods for creating the feature set. This motivates the first application of multivariate feature selection with filters and false discovery rate analysis to biomedical NER, resulting in a feature set at least 3 orders of magnitude smaller than the set created by the rich feature set approach. Finally, two novel approaches to NER by modeling the semantics of token sequences are introduced. The first method focuses on the sequence content by using language models to determine whether a sequence resembles entries in a lexicon of entity names or text from an unlabeled corpus more closely. The second method models the distributional semantics of token sequences, determining the similarity between a potential mention and the token sequences from the training data by analyzing the contexts where each sequence appears in a large unlabeled corpus. The second method is shown to improve the performance of BANNER on multiple data sets.
ContributorsLeaman, James Robert (Author) / Gonzalez, Graciela (Thesis advisor) / Baral, Chitta (Thesis advisor) / Cohen, Kevin B (Committee member) / Liu, Huan (Committee member) / Ye, Jieping (Committee member) / Arizona State University (Publisher)
Created2013
Description
Text mining of biomedical literature and clinical notes is a very active field of research in biomedical science. Semantic analysis is one of the core modules for different Natural Language Processing (NLP) solutions. Methods for calculating semantic relatedness of two concepts can be very useful in solutions solving different problems such as relationship extraction, ontology creation and question / answering [1–6]. Several techniques exist in calculating semantic relatedness of two concepts. These techniques utilize different knowledge sources and corpora. So far, researchers attempted to find the best hybrid method for each domain by combining semantic relatedness techniques and data sources manually. In this work, attempts were made to eliminate the needs for manually combining semantic relatedness methods targeting any new contexts or resources through proposing an automated method, which attempted to find the best combination of semantic relatedness techniques and resources to achieve the best semantic relatedness score in every context. This may help the research community find the best hybrid method for each context considering the available algorithms and resources.
ContributorsEmadzadeh, Ehsan (Author) / Gonzalez, Graciela (Thesis advisor) / Greenes, Robert (Committee member) / Scotch, Matthew (Committee member) / Arizona State University (Publisher)
Created2016
Description
Question answering is a challenging problem and a long term goal of Artificial Intelligence. There are many approaches proposed to solve this problem, including end to end machine learning systems, Information Retrieval based approaches and Textual Entailment. Despite being popular, these methods find difficulty in solving problems that require multi level reasoning and combining independent pieces of knowledge, for example, a question like "What adaptation is necessary in intertidal ecosystems but not in reef ecosystems?'', requires the system to consider qualities, behaviour or features of an organism living in an intertidal ecosystem and compare with that of an organism in a reef ecosystem to find the answer. The proposed solution is to solve a genre of questions, which is questions based on "Adaptation, Variation and Behavior in Organisms", where there are various different independent sets of knowledge required for answering questions along with reasoning. This method is implemented using Answer Set Programming and Natural Language Inference (which is based on machine learning ) for finding which of the given options is more probable to be the answer by matching it with the knowledge base. To evaluate this approach, a dataset of questions and a knowledge base in the domain of "Adaptation, Variation and Behavior in Organisms" is created.
ContributorsBatni, Vaishnavi (Author) / Baral, Chitta (Thesis advisor) / Anwar, Saadat (Committee member) / Yang, Yezhou (Committee member) / Arizona State University (Publisher)
Created2019