Matching Items (2)
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- All Subjects: Physical anthropology
- Creators: Hill, Kim
Description
Yersinia enterocolitica is a major foodborne pathogen found worldwide that causes approximately 87,000 human cases and approximately 1,100 hospitalizations per year in the United States. Y. enterocolitica is a very unique pathogen with the domesticated pig acting as the main animal reservoir for pathogenic bio/serotypes, and as the primary source of human infection. Similar to other gastrointestinal infections, Yersinia enterocolitica is known to trigger autoimmune responses in humans. The most frequent complication associated with Y. enterocolitica is reactive arthritis - an aseptic, asymmetrical inflammation in the peripheral and axial joints, most frequently occurring as an autoimmune response in patients with the HLA-B27 histocompatability antigen. As a foodborne illness it may prove to be a reasonable explanation for some of the cases of arthritis observed in past populations that are considered to be of unknown etiology. The goal of this dissertation project was to study the relationship between the foodborne illness -Y. enterocolitica, and the incidence of arthritis in individuals with and without contact with the domesticated pig.
ContributorsBrown, Starletta (Author) / Hurtado, Ana M (Thesis advisor) / Chowell-Puente, Gerardo (Committee member) / Hill, Kim (Committee member) / Arizona State University (Publisher)
Created2015
Description
This study explores how early modern humans used stone tool technology to adapt to changing climates and coastlines in the Middle Stone Age of South Africa. The MSA is associated with the earliest fossil evidence for modern humans and complex cultural behaviors during a time period of dramatic climate change. Human culture allows for the creation, use, and transmission of technological knowledge that can evolve with changing environmental conditions. Understanding the interactions between technology and the environment is essential to illuminating the role of culture during the origin of our species. This study is focused on understanding ancient tool use from the study of lithic edge damage patterns at archaeological assemblages in southern Africa by using image-based quantitative methods for analyzing stone tools. An extensive experimental program using replicated stone tools provides the comparative linkages between the archaeological artifacts and the tasks for which they were used. MSA foragers structured their tool use and discard behaviors on the landscape in several ways – by using and discarding hunting tools more frequently in the field rather than in caves/rockshelters, but similarly in coastal and interior contexts. This study provides evidence that during a significant microlithic technological shift seen in southern Africa at ~75,000 years ago, new technologies were developed alongside rather than replacing existing technologies. These results are compared with aspects of the European archaeological record at this time to identify features of early human technological behavior that may be unique to the evolutionary history of our species.
ContributorsSchoville, Benjamin J (Author) / Marean, Curtis W (Thesis advisor) / Barton, Michael (Committee member) / Hill, Kim (Committee member) / Arizona State University (Publisher)
Created2016