Building energy assessment often focuses on the use of electricity and natural gas during the use phase of a structure while ignoring the energy investments necessary to construct the facility. This research develops a methodology for quantifying the “embedded” energy and greenhouse gases (GHG) in the building infrastructure of an entire metropolitan region. “Embedded” energy and GHGs refer to the energy necessary to manufacture materials and construct the infrastructure. Using these methods, a case study is developed for Los Angeles County.