Background: ACEs has been associated with stress and violence in prior research. More research is needed to set up gender differences between males and females displaying violence and stress in response to ACEs. Objectives: This study investigated the effects of ACEs and gender on exhibited frequencies of violence and stress within youth. Methods: This study used descriptive statistics and regression to examine the relationships between gender and aces on violence and stress using data from the Arizona Youth Survey (AYS). Interactions were included to evaluate if gender moderated the effect of ACEs. Results: Analyses showed that ACEs significantly impacted youths’ engagement in violence and experiences of stress. Additionally, boys engaged in more violence while girls experienced increased stress. Interaction effects were not substantial as compared to the main effects of ACEs and gender. Conclusion: Given the results, youth interventions should focus on the overall impact of ACEs, regardless of gender.