Matching Items (4)
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- All Subjects: Affect
- Creators: Davis, Mary
- Creators: Roberts, Nicole A.
- Status: Published
Description
Fibromyalgia (FM) is a chronic musculoskeletal disorder characterized by widespread pain, fatigue, and a variety of other comorbid physiological and psychological characteristics, including a deficit of positive affect. Recently, the focus of research on the pathophysiology of FM has considered the role of a number of genomic variants. In the current manuscript, case-control analyses did not support the hypothesis that FM patients would differ from other chronic pain groups in catechol-O-methyltransferase (COMT) and mu-opioid receptor (OPRM1) genotype. However, evidence is provided in support of the hypothesis that functional single nucleotide polymorphisms on the COMT and OPRM1 genes would be associated with risk and resilience, respectively, in a dual processing model of pain-related positive affective regulation in FM. Forty-six female patients with a physician-confirmed diagnosis of FM completed an electronic diary that included once-daily assessments of positive affect and soft tissue pain. Multilevel modeling yielded a significant gene X environment interaction, such that individuals with met/met genotype on COMT experienced a greater decline in positive affect as daily pain increased than did either val/met or val/val individuals. A gene X environment interaction for OPRM1 also emerged, indicating that individuals with at least one asp allele were more resilient to elevations in daily pain than those homozygous for the asn allele. In sum, the findings offer researchers ample reason to further investigate the contribution of the catecholamine and opioid systems, and their associated genomic variants, to the still poorly understood experience of FM.
ContributorsFinan, Patrick Hamilton (Author) / Zautra, Alex (Thesis advisor) / Davis, Mary (Committee member) / Lemery-Chalfant, Kathryn (Committee member) / Presson, Clark (Committee member) / Arizona State University (Publisher)
Created2011
Description
The present study examined daily survey data collected from married couples over the course roughly 14 days. I investigated the relationships of the morning quality ratings of three distinct spousal interactions conversation (physical affection, and sexual activity) reported in mornings on later-day positive and negative affect, as well as next-day intensity of negative somatic symptoms (e.g. headaches, dizziness, aches and pains). Hierarchical linear modeling was used to estimate path models for both husbands and wives. Direct and indirect effects were observed. Results showed that quality of conversation and physical affection increased later-day positive mood for both husbands and wives; however, positive quality activity increased later-day positive affect for wives only. Quality of sexual activity decreased later-day negative affect for wives only. Less later-day negative affect decreased next-day intensity of symptoms for both husbands and wives. Lastly, quality of sexual activity decreased later-day negative affect, which decreased next-day somatic symptoms for wives. This was the only significant indirect effect. Implications are that high marital quality is important for maintaining psychological health for both spouses, and physical health, particularly for wives.
ContributorsVincelette, Tara (Author) / Burleson, Mary H (Thesis advisor) / Roberts, Nicole A. (Committee member) / Schweitzer, Nicholas J (Committee member) / Arizona State University (Publisher)
Created2012
Description
Background: When studying how humans regulate their affect, it is important to recognize that affect regulation does not occur in a vacuum. As humans are an inherently social species, affect plays a crucial evolutionary role in social behavior, and social behavior likewise assumes an important role in affect and affect regulation. Emotion researchers are increasingly interested the specific ways people help to regulate and dysregulate one another’s affect, though experimental examinations of the extant models and theory are relatively few. This thesis presents a broad theoretical framework for social affect regulation between close others, considering the role of attachment theory and its developmental foundations for social affect regulation in adulthood. Affectionate and responsive touch is considered a major mechanism of regulatory benefit between people, both developmentally and in adulthood, and is the focus of the present investigation. Method: A total sample of 231 heterosexual married couples were recruited from the community. Participants were assigned to engage in affectionate touch or sit quietly, and/or engage in positive conversation prior to a stress task. Physiological data was collected continuously across the experiment. Hypotheses: Phasic respiratory sinus arrhythmia (RSA) was used to index the degree of regulatory engagement during the stressor for those who did and did not touch. It was hypothesized that touch would reduce stress appraisal and thus the need for regulatory engagement. This effect was predicted to be greater for those more anxiously attached while increasing the need for regulatory engagement in those more avoidantly attached. Secondarily, partner effects of attachment on sympathetic activation via pre-ejection period (PEP) change were tested. It was predicted that both attachment dimensions would predict a decrease in partner PEP change in the touch condition, with avoidant attachment having the strongest effect. Results: Hierarchical linear modeling techniques were used to account for nonindependence in dyadic observations. The first set of hypotheses were not supported, while the second set were partially supported. Wives’ avoidance significantly predicted husbands’ PEP change, but in the positive direction. This effect also significantly increased in the touch condition. Theoretical considerations and limitations are discussed.
ContributorsParkhurst, David Kevin (Author) / Burleson, Mary H (Thesis advisor) / Roberts, Nicole A. (Committee member) / Mickelson, Kristin D (Committee member) / Arizona State University (Publisher)
Created2017
Description
Experiencing poor, unrefreshing sleep is a common occurrence for individuals with chronic pain. Sleep disturbance predicts not only greater pain and disability, but also heightened negative affect and reduced positive affect in individuals with chronic pain. Such fluctuations in affect have been linked with more negative and fewer positive social events. For those with chronic pain, negative social relations can exacerbate pain, whereas positive social interactions can help decrease disability. Thus, exploring the sleep‒social functioning process in chronic pain may be one way to improve daily functioning and quality of life. The current study examined positive and negative affect as two parallel mediators of the within-day relations between sleep quality and positive and negative social events in individuals with chronic pain. For 21 days, electronic daily diary reports were collected from 220 individuals with fibromyalgia, a condition characterized by widespread chronic pain. Within-person relations among reports of last night’s sleep quality, afternoon affects and pain, and evening social events were estimated via multilevel structural equation modeling. Findings showed that positive affect mediated both the sleep quality‒positive social events and sleep quality‒negative social events relations. That is, greater than usual sleep disturbance last night predicted afternoon reports of lower than usual positive affect. Low positive affect, in turn, predicted evening reports of fewer than usual positive social events and more than usual negative social events that day, controlling for the effects of afternoon pain. In addition, negative affect mediated the sleep quality‒negative social events link. That is, greater than usual sleep disturbance last night predicted afternoon reports of higher than usual negative affect, which, in turn, predicted evening reports of more than usual negative social events that day, controlling for the effects of afternoon pain. Of the three significant mediated paths, the sleep quality‒positive affect‒positive social events path was the strongest in magnitude. Thus, a night of poor sleep can have an impact on social events the next day in those with chronic pain by dysregulating affect. Further, findings highlight the key role of positive affect in the sleep‒social functioning process and potential socio-affective benefits of sleep interventions in chronic pain.
ContributorsKothari, Dhwani J. (Author) / Davis, Mary (Thesis advisor) / Luecken, Linda (Committee member) / Karoly, Paul (Committee member) / Infurna, Frank (Committee member) / Arizona State University (Publisher)
Created2019