In this study, potential differences in the manifestation and rates of eating disorders and symptoms (body dissatisfaction, weight and shape concerns, food restriction, and compensatory behaviors) in college women across sexual orientations were examined. The sociocultural model of eating disorders was also examined for these women across sexual orientations. The participants were organized into three different sexual orientation groups for analysis: heterosexual (group 1), bisexual, pansexual, and polysexual (group 2), and lesbian, gay, queer, transsexual, asexual, and other (group 3). Using cross-sectional data, it was revealed that there were significant group differences when comparing the three sexual orientation groups on loss of control over eating, but no significant group differences on body dissatisfaction, thin ideal internalization, and weight-related eating pathology, and total eating disorder symptoms scores. The sociocultural model was not predictive of eating disorder symptoms among non-heterosexual groups. Longitudinal analyses revealed that the sociocultural model of eating disorders prospectively predicts eating disorder symptoms among heterosexual women, but not non-heterosexual women. Both cross-sectional and longitudinal analyses indicate that non-heterosexual women may be protected from societal pressure to subscribe to the thin ideal and its subsequent internalization. However, the comparison group of heterosexual women in our study may not have been completely representative of undergraduate women in terms of total eating disorder symptoms or eating pathology. Additionally, regardless of sexual orientation, our sample reported more total eating disorder symptoms and emotional eating than previous studies. These findings have both clinical and research implications. Future research is needed to determine what risk factors and treatment target variables are relevant for non-heterosexual women.