Matching Items (11)
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- All Subjects: Clinical Psychology
- All Subjects: Middle-aged persons--Psychology.
- Creators: Corbin, William R.
- Member of: Theses and Dissertations
- Resource Type: Text
- Status: Published
Effects of early internalizing symptoms on speed of transition through stages of alcohol involvement
Description
Alcohol use disorders and internalizing disorders are highly comorbid in adults, but how this comorbidity unfolds over development is not well understood. Previous retrospective studies in adults have shown that internalizing problems are associated with a rapid transition from first drink and first regular drinking to the onset of alcohol dependence. Some results also suggest that internalizing is a stronger predictor of rapid transitions through later stages of alcohol involvement, but these stage-specific effects have not been explicitly tested. The present study utilized a prospective dataset to investigate effects of adolescent internalizing symptoms on speed of transition through multiple stages of alcohol involvement. Specifically, it was hypothesized that greater early internalizing symptoms would predict a later age of first drink, a slower transition from first drink to first binge, and a faster transition from first binge to first dependence symptom. The moderating effects of gender were also examined. Data were from a longitudinal study of children of alcoholics and matched controls (n = 454) followed from late childhood to mid-life. Linear regression and Cox regression were the primary analytic strategies. Covariates were externalizing symptoms, family history of alcohol use disorders, and gender. Analyses also controlled for age at which the participant entered each interval. Generally, stage-specific hypotheses concerning the effects of internalizing were not supported. Internalizing symptoms marginally predicted an earlier age of first drink and a faster transition from first binge to first dependence symptom, and significantly predicted a faster transition through the overall interval from first drink to first dependence symptom. Internalizing was a stronger predictor of rapid transitions for women, and the effects of internalizing were not specific to early or later stages of alcohol involvement among women. These results suggest that early internalizing problems are a general risk factor for a rapid transition through all stages of alcohol involvement, and this risk may be stronger for women than for men. These results have important implications for our theoretical understanding of the relationship between internalizing problems and alcohol use disorders as well as prevention and intervention efforts targeting these problems.
ContributorsMenary, Kyle (Author) / Corbin, William R. (Thesis advisor) / Chassin, Laurie A (Committee member) / Meier, Madeline H (Committee member) / Arizona State University (Publisher)
Created2014
Description
Variability in subjective response to alcohol has been shown to predict drinking behavior as well as the development of alcohol use disorders. The current study examined the extent to which individual differences in alcohol pharmacokinetics impact subjective response and drinking behavior during a single session alcohol administration paradigm. Participants (N = 98) completed measures of subjective response at two time points following alcohol consumption. Pharmacokinetic properties (rate of absorption and metabolism) were inferred using multiple BAC readings to calculate the area under the curve during the ascending limb for absorption and descending limb for metabolism. Following the completion of the subjective response measures, an ad-libitum taste rating task was implemented in which participants were permitted to consume additional alcoholic beverages. The amount consumed during the taste rating task served as the primary outcome variable. Results of the study indicated that participants who metabolized alcohol more quickly maintained a greater level of subjective stimulation as blood alcohol levels declined and reported greater reductions in subjective sedation. Although metabolism did not have a direct influence on within session alcohol consumption, a faster metabolism did relate to increased ad-libitum consumption indirectly through greater acute tolerance to sedative effects and greater maintenance of stimulant effects. Rate of absorption did not significantly predict subjective response or within session drinking. The results of the study add clarity to theories of subjective response to alcohol, and suggest that those at highest risk for alcohol problems experience a more rapid reduction in sedation following alcohol consumption while simultaneously experiencing heightened levels of stimulation. Variability in pharmacokinetics, namely how quickly one metabolizes alcohol, may be an identifiable biomarker of subjective response and may be used to infer risk for alcohol problems.
ContributorsBoyd, Stephen (Author) / Corbin, William R. (Thesis advisor) / Chassin, Laurie (Committee member) / MacKinnon, David (Committee member) / Olive, Michael Foster (Committee member) / Arizona State University (Publisher)
Created2014
Description
Self-control has been shown to predict both health risk and health protective outcomes. Although top-down or “good” self-control is typically examined as a unidimensional construct, research on “poor” self-control suggests that multiple dimensions may be necessary to capture aspects of self-control. The current study sought to create a new brief survey measure of top-down self-control that differentiates between self-control capacity, internal motivation, and external motivation. Items were adapted from the Brief Self-Control Scale (BSCS; Tangney, Baumeister, & Boone, 2004) and were administered through two online surveys to 347 undergraduate students enrolled in introductory psychology courses at Arizona State University. The Self-Control Motivation and Capacity Survey (SCMCS) showed strong evidence of validity and reliability. Exploratory and confirmatory factor analyses supported a 3-factor structure of the scale consistent with the underlying theoretical model. The final 15-item measure demonstrated excellent model fit, chi-square = 89.722 p=.077, CFI = .989, RMSEA = .032, SRMR = .045. Despite several limitations including the cross-sectional nature of most analyses, self-control capacity, internal motivation, and external motivation uniquely related to various self-reported behavioral outcomes, and accounted for additional variance beyond that accounted for by the BSCS. Future studies are needed to establish the stability of multiple dimensions of self-control, and to develop state-like and domain-specific measures of self-control. While more research in this area is needed, the current study demonstrates the importance of studying multiple aspects of top-down self-control, and may ultimately facilitate the tailoring of interventions to the needs of individuals based on unique profiles of self-control capacity and motivation.
ContributorsPapova, Anna (Author) / Corbin, William R. (Thesis advisor) / Karoly, Paul (Committee member) / Brewer, Gene (Committee member) / Arizona State University (Publisher)
Created2016
Description
The current dissertation combines the results of three recently published papers focused on impulsive personality traits, alcohol and cannabis co-use, and alcohol misuse. The first study used alcohol administration to test whether different impulsivity facets conferred risk for heightened alcohol craving through subjective alcohol response patterns. The second study built on this study by incorporating alcohol and cannabis co-use into the acquired preparedness model, using longitudinal data. This study tested whether generalized impulsivity and sensation seeking during late adolescence predisposed individuals to co-use alcohol and cannabis, and whether co-use was indirectly associated with alcohol problems ten years later through positive expectancies and heavy drinking. The third study tested whether impulsive traits moderated the day-level effect of alcohol and cannabis co-use (vs. alcohol-only) on within-person deviations in drinking quantity on drinking days. Through the combination of these three studies, this dissertation seeks to further advance the literature on multiplicative ways in which personality enacts risk for heavy drinking, alcohol and cannabis co-use, and alcohol problems.
ContributorsWaddell, Jack T. (Author) / Corbin, William R. (Thesis advisor) / Chassin, Laurie (Committee member) / Grimm, Kevin J. (Committee member) / Meier, Madeline H. (Committee member) / Arizona State University (Publisher)
Created2024
Description
Both subjective response to alcohol and acute tolerance possess unique biphasic relations with the blood alcohol concentration curve. However, prior work has generally failed to examine shared relations between the two constructs and has yet to consider the full valence by arousal affective space of subjective response, nor individual differences in metabolism or peak levels of subjective intoxication. As such, the present study sought to characterize acute tolerance to subjective response in addition to examining relations between acute tolerance, subjective response, and related outcomes. Participants (N=258) were randomly assigned to receive alcohol (target blood alcohol concentration = .08 g%) as part of a large placebo-controlled alcohol administration study. Participant family history of alcohol use problems and personal history of alcohol use were collected at baseline. Subjective response to alcohol was assessed across the full valence by arousal affective space at equivalent points on the ascending and descending limbs of the blood alcohol concentration curve. Latent change scores were calculated to characterize the development of acute tolerance, and path analyses tested relations between acute tolerance to subjective response, concurrent patterns of alcohol use, and negative alcohol-related consequences. Age, sex, race/ethnicity, and drinking context were included as covariates. Acute tolerance to low arousal positive (i.e., relaxed, mellow) effects were found to be inversely related to negative consequences such that a maintenance of low arousal positive effects was associated with more negative consequences. The amount of time elapsed between measurements was found to be significantly related to the development of acute tolerance to high arousal positive (i.e., talkative, stimulated) effects, such that more time between measurements was related to a greater decrease in high arousal positive effects. Peak high arousal positive effects were found to be related to increased drinking and indirectly related to more negative consequences via drinking, whereas high arousal negative was protective against increased drinking and negative consequences. Results suggest that a maintenance of negatively reinforcing effects across the blood alcohol concentration curve may confer risk for negative consequences. Results also suggest that considering individual differences in alcohol metabolism may be useful in understanding alcohol’s rewarding, stimulating effects.
ContributorsKing, Scott Edward (Author) / Corbin, William R. (Thesis advisor) / Chassin, Laurie (Committee member) / Grimm, Kevin (Committee member) / Arizona State University (Publisher)
Created2022
Description
Self-control has been shown to be an important influence behind a variety of risk and protective behaviors, such as substance abuse. Although prior research points to the existence of multiple dimensions of self-control, this concept is not consistently defined and frequently only studied as a conglomerate in clinical research. The current study sought to examine how two experimental manipulations of subcomponents of self-control (motivation and self-efficacy) affect real-world consumptive behavior after accounting for executive function. Additionally, the validity and reliability of a brief state survey measure of perceived self-control capacity, internal motivation, and external motivation was tested. The goal was to examine how basic scientific principles involved in self-control translate into clinically relevant behaviors, which may inform understanding of momentary lapses in self-control behavior, potentially leading to novel prevention and intervention efforts. 94 college students completed a 1-2 hour laboratory protocol during which they completed survey and laboratory-based tasks of self-control and related behaviors, executive function, and ad libitum alcohol consumption. Results showed that the self-efficacy manipulation successfully increased perceived self-control capacity, although this did not lead to a significant reduction in consumption. The motivation manipulation neither increased motivation nor reduced consumption in this sample. However, the brief state survey measure of self-control subcomponents demonstrated strong test-retest reliability and distinction from trait self-control, demonstrating its viability for use in future research. By elucidating the relationships between specific mechanisms of self-control, laboratory-based tasks and manipulations, and real-world consumptive behaviors, prevention and intervention efforts for problems such as alcohol abuse may be tailored to the needs of the individual and made more impactful and cost-effective.
ContributorsPapova, Anna (Author) / Corbin, William R. (Thesis advisor) / Brewer, Gene (Committee member) / Karoly, Paul (Committee member) / McClure, Samuel (Committee member) / Arizona State University (Publisher)
Created2020
Description
High-risk sexual behavior (HRSB) and substance use (SU) are highly prevalent in the general population with adolescents and young adults at high risk for engaging in these behaviors. Unhealthy behavioral patterns established during these developmental periods can have detrimental long-term effects on physical and mental health. Health care expenditures, related to consequences of these behaviors, have been estimated to reach around $740 billion in the United States, indicating an imminent public health concern. Unfortunately, little is known about trajectories and risk factors of health risk behaviors (HRBs) beyond age 25, which is a critical developmental period regarding these behaviors. This study sought to better understand HRB trajectories throughout young adulthood as well as the mechanisms underlying the initiation and progression of these behaviors. This study used data from a large (n = 998), longitudinal, randomized-controlled trial with intensive measurement of HRBs and peer and family processes. Growth mixture modeling estimated gender-specific trajectories of HRSB and SU (tobacco, alcohol, marijuana) from ages 22-30. Multinomial logistic regression (MLR) then examined how family and peer factors, and trauma exposure during adolescence, both separately and in combination, influenced HRB trajectories. Four unique trajectories resulted for SU (low use class; increasing use class; decreasing use class; high use class) and three for HRSB (low HRSB class; increasing HRSB class; deceasing HRSB class). There were no differences in the number of classes or trajectory patterns between men and women. Results of the MLRs demonstrated that deviant peer affiliation (DP), family conflict, parental monitoring and trauma exposure impacted trajectories of tobacco and marijuana use and HRSB during young adulthood, but that the most salient influences were DP and trauma exposure. Alcohol use trajectories and differences between the increasing, decreasing and high trajectory classes for the other HRBs were difficult to predict. These results suggest that young adults are still at risk for engaging in HRBs, and there are risk factors in adolescence that influence typologies of HRBs during this developmental period. Prevention and intervention programs targeting young adulthood are needed, and better understanding factors that lead to vulnerabilities specific to this developmental period may inform targeted interventions.
ContributorsPanza, Kaitlyn Elizabeth (Author) / Corbin, William R. (Thesis advisor) / Tein, Jenn-Yun (Thesis advisor) / Crnic, Keith A. (Committee member) / Ha, Thao (Committee member) / Arizona State University (Publisher)
Created2019
Description
Interpersonal strain is linked with depressive symptoms in middle-aged adults. Self-compassion is an emerging resilience construct that may be advantageous in navigating relationship strain by helping individuals respond to emotions in a kind and nonjudgmental way. Although theory and empirical evidence suggests that self-compassion is protective against the impact of stress on mental health outcomes, many studies have not investigated how self-compassion operates in the context of relationship strain. In addition, few studies have examined psychological or physiological mechanisms by which self-compassion protects against mental health outcomes, depression in particular. Thus, this study examined 1) the extent to which trait self-compassion buffers the relation between family strain and depressive symptoms, and 2) whether these buffering effects are mediated by hope and inflammatory processes (IL-6) in a sample of 762 middle-aged, community-dwelling adults. Results from structural equation models indicated that family strain was unrelated to depressive symptoms and the relation was not moderated by self-compassion. Hope, but not IL-6, mediated the relation between family strain and depressive symptoms and the indirect effect was not conditional on levels of self-compassion. Taken together, the findings suggest that family strain may lead individuals to experience less hope and subsequent increases in depressive symptoms, and further, that a self-compassionate attitude does not affect this relation. Implications for future self-compassion interventions are discussed.
ContributorsMistretta, Erin (Author) / Davis, Mary C. (Thesis advisor) / Karoly, Paul (Committee member) / Infurna, Frank (Committee member) / Arizona State University (Publisher)
Created2019
Description
Background: Hash oil, a cannabis preparation that contains ultra-high concentrations of tetrahydrocannabinol (THC), is quickly gaining popularity in the United States. Some evidence suggests that hash oil might produce greater intoxication and more severe negative effects than marijuana. This study examined whether the subjective effects of hash oil are more extreme than the subjective effects of marijuana and whether frequency of hash oil use is associated with the subjective effects of marijuana and hash oil. Method: Past-year cannabis users (n = 1,268) were recruited online to complete a questionnaire about the subjective effects of cannabis. Participants who reported past-year use of both hash oil and marijuana (n = 574) rated subjective effects of each type of cannabis in the following positive and negative domains: positive affect, cognitive enhancement, negative affect, cognitive impairment, physiological effects, reduced consciousness, and psychotic-like experiences. Results: Results of within-person comparisons showed that hash oil was rated as producing lesser positive effects (Hash oil: M = 4.53, Marijuana: M = 5.55, t = 14.67, p < .001) than marijuana. Negative effects of hash oil were minimal for the full sample (n = 574) and for both frequent and infrequent hash oil users. In general, the frequency of hash oil use was not associated with the subjective effects of marijuana but more frequent hash oil use was associated with rating hash oil as producing greater positive effects ( = 0.28, t = 6.86, p < .001) and lesser negative effects ( = -0.16, t = -3.83, p < .001). Findings were unchanged after controlling for sex, medical cannabis use, and frequency of marijuana use.
Conclusions: Hash oil produced lesser positive effects than marijuana. Negative effects of hash oil were minimal, suggesting that extreme negative effects may be unlikely for experienced cannabis users.
Conclusions: Hash oil produced lesser positive effects than marijuana. Negative effects of hash oil were minimal, suggesting that extreme negative effects may be unlikely for experienced cannabis users.
ContributorsOkey, Sarah Arlene (Author) / Meier, Madeline H (Thesis advisor) / Corbin, William R. (Committee member) / Doane, Leah D (Committee member) / Arizona State University (Publisher)
Created2019
Description
Lifespan psychological perspectives have long suggested the context in which individuals live having the potential to shape the course of development across the adult lifespan. Thus, it is imperative to examine the role of both the objective and subjective neighborhood context in mitigating the consequences of lifetime adversity on mental and physical health. To address the research questions, data was used from a sample of 362 individuals in midlife who were assessed on lifetime adversity, multiple outcomes of mental and physical health and aspects of the objective and subjective neighborhood. Results showed that reporting more lifetime adversity was associated with poorer mental and physical health. Aspects of the objective and subjective neighborhood, such as green spaces moderated these relationships. The discussion focuses on potential mechanisms underlying why objective and subjective indicators of the neighborhood are protective against lifetime adversity.
ContributorsStaben, Omar E (Author) / Infurna, Frank J. (Thesis advisor) / Luthar, Suniya S. (Committee member) / Grimm, Kevin J. (Committee member) / Arizona State University (Publisher)
Created2019