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Factors that Contribute Toward Volunteer Satisfaction and Retention Rate of Alas de Amor: A Collaboration Between Alas de Amor and the C.A.R.E. Program

Description
Alas de Amor is a fairly new organization whose most significant need right now is to grow in numbers and remain growing. This growth is important to the organization because it will allow them to not only treat and see more patients while in Mexico, but it will also benefit…

Alas de Amor is a fairly new organization whose most significant need right now is to grow in numbers and remain growing. This growth is important to the organization because it will allow them to not only treat and see more patients while in Mexico, but it will also benefit the organization in terms of presence in the Phoenix area and general knowledge of the organization. Volunteers are in some ways are unpaid marketing tools because they tell their peers about the experiences they have and encourage those they know to join the cause as well ("Why Involve Volunteers?," n.d.). As demonstrated through prior research on volunteering, volunteer motivations and satisfaction play an important role in retaining volunteers. Thus, the aim of this study was to evaluate the motivations, satisfaction, and likelihood of continuation in volunteering for the individuals who have served as volunteers at Alas de Amor within the past year.
ContributorsFriedland, Juliette Marie (Author) / Gaertner, Bridget (Thesis director) / Dumka, Larry (Committee member) / School of Nutrition and Health Promotion (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Modeling SDF-1α Chemotactic Gradient Formation After Traumatic Brain Injury

Description
Traumatic brain injury (TBI) is a leading cause of injury related death in the United States. The complexity of the injury environment that follows TBI creates an incomplete understanding of all the mechanisms in place to regulate chemotactic responses to TBI. The goal of this project was to develop a…

Traumatic brain injury (TBI) is a leading cause of injury related death in the United States. The complexity of the injury environment that follows TBI creates an incomplete understanding of all the mechanisms in place to regulate chemotactic responses to TBI. The goal of this project was to develop a predictive in silco model using diffusion and autocrine/paracrine signaling specific to stromal cell derived factor-1α (SDF-1α) gradient formation after TBI and compare this model with in vivo experimental data. A COMSOL model using Fickian diffusion and autocrine/paracrine reaction terms was generated to predict the gradient formation observed in vivo at three physiologically relevant time points (1, 3, and 7 days). In vivo data was gathered and analyzed via immunohistochemistry and MATLAB. The spatial distribution of SDF-1α concentration in vivo more consistently demonstrated patterns similar to the in silico model dependent on both diffusion and autocrine/paracrine reaction terms rather than diffusion alone. The temporal distribution of these same results demonstrated degradation of SDF-1α at too rapid a rate, compared to the in vivo results. To account for differences in behavior observed in vivo, reaction terms and constants of 1st-order reaction rates must be modulated to better reflect the results observed in vivo. These results from both the in silico model and in vivo data support the hypothesis that SDF-1α gradient formation after TBI depends on more than diffusion alone. Future work will focus on improving the model with constants that are specific to SDF-1α as well as testing methods to better control the degradation of SDF-1α.
ContributorsFreeman, Sabrina Louise (Author) / Stabenfeldt, Sarah (Thesis director) / Caplan, Michael (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05