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This study examines cognitive and motor function in adolescents with Down syndrome (DS) following an 8-week assisted cycling therapy intervention. Forty-four participants were randomly assigned to three groups consisting of an assisted cycling (AC) (i.e., exercise accomplished through the use of a motor), a voluntary cycling (VC) (self-selected cadence), and

This study examines cognitive and motor function in adolescents with Down syndrome (DS) following an 8-week assisted cycling therapy intervention. Forty-four participants were randomly assigned to three groups consisting of an assisted cycling (AC) (i.e., exercise accomplished through the use of a motor), a voluntary cycling (VC) (self-selected cadence), and a no cycling (NC) control group. Both ACT and VC groups rode a stationary bicycle for three 30-minute sessions a week, for a total of eight weeks. Participants completed cognitive testing that assessed information processing and manual dexterity at the beginning and at the end of the 8-week intervention. Consistent with our hypothesis, the results showed that information processing and manual dexterity improved following 8 weeks of cycling for the ACT group. These results were not seen for individuals in the voluntary and non-exercise groups. Our results suggest that assisted cycling therapy may induce permanent changes in the prefrontal cortex in adolescents with DS.
ContributorsJimenez, Andrew (Author) / Ringenbach, Shannon (Thesis director) / Kulinna, Pamela (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2015-05
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Description
The purpose of this study, originally, was to contribute to the completion of a meta-analysis conducted by Mara Wierstra from the University of Virginia. Wierstra had requested individual participant data from two separate studies conducted in our lab: "Acute bouts of assisted cycling improves cognitive and upper extremity movement functions

The purpose of this study, originally, was to contribute to the completion of a meta-analysis conducted by Mara Wierstra from the University of Virginia. Wierstra had requested individual participant data from two separate studies conducted in our lab: "Acute bouts of assisted cycling improves cognitive and upper extremity movement functions in adolescents with Down syndrome" and "Assisted Cycling Therapy (ACT) improves inhibition in adolescents with autism spectrum disorder." From the data requested, the participants were required to complete three separate tests (i.e., Tower of London, Trail Making Task and the Stroop Test). After compiling the data and sending it to her, we decided to conduct a small meta-analysis of our own, drawing connecting conclusions from the data from the two studies. We concluded that observationally our data suggest an advantage for ACT over voluntary cycling and no cycling across two separate populations (i.e., Autism Spectrum Disorder and Down syndrome), and across different measures of executive function (i.e., Stroop Test, Trail Making Test, and Tower of London). The data suggest that the ACT interventions may promote the upregulation of neurotropic factors leading to neurogenesis in the prefrontal cortex of the brain.
ContributorsParker, Cade Joseph (Author) / Ringenbach, Shannon (Thesis director) / Holzapfel, Simon (Committee member) / School of Nutrition and Health Promotion (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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Description
The aim of this study is to understand the affects of grip strength and manual dexterity in activities of daily living (ADL) in persons with Down syndrome (DS). This is important because it could help with future interventions that are focused around improving related disadvantages in this particular population. Ten

The aim of this study is to understand the affects of grip strength and manual dexterity in activities of daily living (ADL) in persons with Down syndrome (DS). This is important because it could help with future interventions that are focused around improving related disadvantages in this particular population. Ten participants with DS performed the manual dexterity tests (i.e., Purdue Pegboard) and measured their grip strength with a hydraulic dynamometer. Overall, grip strength was lower than the average for the typical population and was reduced after aeorbic exercise. Improvements, however, were found in their manual dexterity from pre-test to post-test. This indicates that the assisted moderate intensity exercise intervention helped their dexterity performance. The improvements in dexterity are consistent with previous research conducted by Ringenbach et al. (2007). These results suggest that a moderate intensity treadmill walking exercise intervention can increase precision and efficiency in dexterity in persons with Down syndrome, however their grip force production may be stimulated by another means.
ContributorsSemper, Logan (Author) / Ringenbach, Shannon (Thesis director) / Kulinna, Pamela (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2012-12
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Description
This study examined upper extremity function, including manual dexterity, in chronic stroke survivors following a 10-week high intensity interval treadmill walking intervention. Six stroke survivors completed two 35-minute high intensity interval treadmill walking sessions based on ventilatory threshold per week. In addition, each participant completed one 30-minute low-intensity walking session

This study examined upper extremity function, including manual dexterity, in chronic stroke survivors following a 10-week high intensity interval treadmill walking intervention. Six stroke survivors completed two 35-minute high intensity interval treadmill walking sessions based on ventilatory threshold per week. In addition, each participant completed one 30-minute low-intensity walking session at home. Participants completed upper extremity and manual dexterity testing at baseline, acutely, and after the 10-week intervention. Contrary to the prediction made, significant improvements in both paretic and non-paretic upper-extremity function including manual dexterity were not found. While time to complete the Nine Hole Peg Test (9HPB) somewhat decreased and the number of blocks transferred in the Box and Blocks Test (BBT) slightly increased, results were not found to be statistically significant. The results do suggest, nonetheless, that high intensity interval treadmill training may lead to improvements in upper extremity function and potentially daily living in chronic stroke survivors.
ContributorsHatty, Laura Elizabeth (Author) / Ringenbach, Shannon (Thesis director) / Bosch, Pamela (Committee member) / Holzapfel, Simon (Committee member) / School of Nutrition and Health Promotion (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Description

The primary goal of this study is to assess and develop an understanding of the effects of Assisted Cycling Therapy on manual motor performance in children with Down syndrome. Seven children (Mage 11.6 years old) completed a 30-minute cycle session 2x/week for 8 weeks on the PACT bicycle at a

The primary goal of this study is to assess and develop an understanding of the effects of Assisted Cycling Therapy on manual motor performance in children with Down syndrome. Seven children (Mage 11.6 years old) completed a 30-minute cycle session 2x/week for 8 weeks on the PACT bicycle at a 35% greater rate than their self-selected rate. Pre- and post-testing of grip force with a dynamometer and unimanual and bimanual manual dexterity using the Purdue Pegboard were measured to determine changes in force production and fine motor control, respectively. Results consistently showed improvements in grip force in both hands and bimanual dexterity following PACT. My results are interpreted with respect to cerebral lateralization and neuroplasticity following PACT intervention.

ContributorsGunther, Bryn (Author) / Ringenbach, Shannon (Thesis director) / Ofori, Edward (Committee member) / Rand, Miya (Committee member) / Rafie, Fourozan (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor)
Created2023-05