The ever-increasing importance of cancer and neurodegenerative diseases continues to grow as populations across the world are affected by death and aging. The vitamin A (RXR) and vitamin D (VDR) receptor pathways offer promising potential to aid in treatment of cancer and Alzheimer’s disease. This thesis discusses the potential application of novel analogs of Bexarotene (RXR agonist), MeTC7 (a new potent VDR antagonist), and vitamin D as possible therapeutics for cancer and Alzheimer’s disease.

The decision to disclose or not disclose information is a personal choice. When medical information is learned, a patient has to make decisions about disclosure. This qualitative research project has the goal of understanding how Latinx participants' cultural values, experiences from this community, and other factors influence the decision to disclose in a romantic relationship. Twelve interviews were conducted using a semi-structured interview guide and the main themes found from analysis of the data cultural and relational influencers. This thesis serves as a resource for healthcare professionals to better understand their Latinx patient population in times where disclosure is encountered.

The decision to disclose or not disclose information is a personal choice. When medical information is learned, a patient has to make decisions about disclosure. This qualitative research project has the goal of understanding how Latinx participants' cultural values, experiences from this community, and other factors influence the decision to disclose in a romantic relationship. Twelve interviews were conducted using a semi-structured interview guide and the main themes found from analysis of the data cultural and relational influencers. This thesis serves as a resource for healthcare professionals to better understand their Latinx patient population in times where disclosure is encountered.