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Often termed the "gold standard" in the differential diagnosis of dysarthria, the etiology-based Mayo Clinic classification approach has been used nearly exclusively by clinicians since the early 1970s. However, the current descriptive method results in a distinct overlap of perceptual features across various etiologies, thus limiting the clinical utility of

Often termed the "gold standard" in the differential diagnosis of dysarthria, the etiology-based Mayo Clinic classification approach has been used nearly exclusively by clinicians since the early 1970s. However, the current descriptive method results in a distinct overlap of perceptual features across various etiologies, thus limiting the clinical utility of such a system for differential diagnosis. Acoustic analysis may provide a more objective measure for improvement in overall reliability (Guerra & Lovely, 2003) of classification. The following paper investigates the potential use of a taxonomical approach to dysarthria. The purpose of this study was to identify a set of acoustic correlates of perceptual dimensions used to group similarly sounding speakers with dysarthria, irrespective of disease etiology. The present study utilized a free classification auditory perceptual task in order to identify a set of salient speech characteristics displayed by speakers with varying dysarthria types and perceived by listeners, which was then analyzed using multidimensional scaling (MDS), correlation analysis, and cluster analysis. In addition, discriminant function analysis (DFA) was conducted to establish the feasibility of using the dimensions underlying perceptual similarity in dysarthria to classify speakers into both listener-derived clusters and etiology-based categories. The following hypothesis was identified: Because of the presumed predictive link between the acoustic correlates and listener-derived clusters, the DFA classification results should resemble the perceptual clusters more closely than the etiology-based (Mayo System) classifications. Results of the present investigation's MDS revealed three dimensions, which were significantly correlated with 1) metrics capturing rate and rhythm, 2) intelligibility, and 3) all of the long-term average spectrum metrics in the 8000 Hz band, which has been linked to degree of phonemic distinctiveness (Utianski et al., February 2012). A qualitative examination of listener notes supported the MDS and correlation results, with listeners overwhelmingly making reference to speaking rate/rhythm, intelligibility, and articulatory precision while participating in the free classification task. Additionally, acoustic correlates revealed by the MDS and subjected to DFA indeed predicted listener group classification. These results beget acoustic measurement as representative of listener perception, and represent the first phase in supporting the use of a perceptually relevant taxonomy of dysarthria.
ContributorsNorton, Rebecca (Author) / Liss, Julie (Thesis advisor) / Azuma, Tamiko (Committee member) / Ingram, David (Committee member) / Arizona State University (Publisher)
Created2012
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Description
With a growing number of adults with autism spectrum disorder (ASD), more and more research has been conducted on majority male cohorts with ASD from young, adolescence, and some older age. Currently, males make up the majority of individuals diagnosed with ASD, however, recent research states that the gender ga

With a growing number of adults with autism spectrum disorder (ASD), more and more research has been conducted on majority male cohorts with ASD from young, adolescence, and some older age. Currently, males make up the majority of individuals diagnosed with ASD, however, recent research states that the gender gap is closing due to more advanced screening and a better understanding of how females with ASD present their symptoms. Little research has been published on the neurocognitive differences that exist between older adults with ASD compared to neurotypical (NT) counterparts, and nothing has specifically addressed older women with ASD. This study utilized neuroimaging and neuropsychological tests to examine differences between diagnosis and sex of four distinct groups: older men with ASD, older women with ASD, older NT men, and older NT women. In each group, hippocampal size (via FreeSurfer) was analyzed for differences as well as correlations with neuropsychological tests. Participants (ASD Female, n = 12; NT Female, n = 14; ASD Male, n = 30; NT Male = 22), were similar according to age, IQ, and education. The results of the study indicated that the ASD Group as a whole performed worse on executive functioning tasks (Wisconsin Card Sorting Test, Trails Making Test) and memory-related tasks (Rey Auditory Verbal Learning Test, Weschler Memory Scale: Visual Reproduction) compared to the NT Group. Interactions of sex by diagnosis approached significance only within the WCST non-perseverative errors, with the women with ASD performing worse than NT women, but no group differences between men. Effect sizes between the female groups (ASD female vs. NT female) showed more than double that of the male groups (ASD male vs. NT male) for all WCST and AVLT measures. Participants with ASD had significantly smaller right hippocampal volumes than NT participants. In addition, all older women showed larger hippocampal volumes when corrected for total intracranial volume (TIV) compared to all older men. Overall, NT Females had significant correlations across all neuropsychological tests and their hippocampal volumes whereas no other group had significant correlations. These results suggest a tighter coupling between hippocampal size and cognition in NT Females than NT Males and both sexes with ASD. This study promotes further understanding of the neuropsychological differences between older men and women, both with and without ASD. Further research is needed on a larger sample of older women with and without ASD.
ContributorsWebb, Christen Len (Author) / Braden, B. Blair (Thesis advisor) / Azuma, Tamiko (Committee member) / Dixon, Maria (Committee member) / Arizona State University (Publisher)
Created2019
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Description
Purpose: The present study examined grammatical gender use in child Spanish heritage speakers (HSs) in order to determine whether the differences observed in their grammar, when compared to Spanish monolinguals, stem from an incompletely acquired grammar, in which development stops, or from a restructuring process, in which features from the

Purpose: The present study examined grammatical gender use in child Spanish heritage speakers (HSs) in order to determine whether the differences observed in their grammar, when compared to Spanish monolinguals, stem from an incompletely acquired grammar, in which development stops, or from a restructuring process, in which features from the dominant and the weaker language converge to form a new grammatical system. In addition, this study evaluated whether the differences usually found in comprehension are also present in production. Finally, this study evaluates if HSs differences are the result of the input available to them.

Method: One-hundred and four typically developing children, 48 HSs and 58 monolingual, were selected based on two age groups (Preschool vs. 3rd Grade). Two comprehension and three production experimental tasks were designed for the three different grammatical structures where Spanish expresses gender (determiners, adjectives, and clitic pronouns). Linear mixed-models were used to examine main effects between groups and grammatical structures.

Results: Results from this study showed that HSs scored significantly lower than monolingual speakers in all tasks and structures; however, 3rd-Grade HSs had higher accuracy than PK-HSs. Error patterns were similar between monolinguals and HSs. Moreover, the commonly reported overgeneralization of the masculine form seems to decrease as HSs get older.

Conclusion: These results suggest that HSs’ do not face a case of Incomplete Acquisition or Restructured Grammatical gender system, but instead follow a protracted language development in which grammatical skills continue to develop after preschool years and follow the same developmental patterns as monolingual children
ContributorsMartinez-Nieto, Lourdes (Author) / Restrepo, Maria Adelaida (Thesis advisor) / Renaud, Claire (Thesis advisor) / Pascual y Cabo, Diego (Committee member) / Thompson, Marilyn (Committee member) / Ingram, David (Committee member) / Arizona State University (Publisher)
Created2018
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Description
A substantial amount of research demonstrates that preschoolers' phonological awareness skills are a robust predictor of children's later decoding ability. Several investigators examined performance of children with speech sound impairment (SSI), defined as inaccurate production of speech sounds in the absence of any etiology or communication impairment, on phonological awareness

A substantial amount of research demonstrates that preschoolers' phonological awareness skills are a robust predictor of children's later decoding ability. Several investigators examined performance of children with speech sound impairment (SSI), defined as inaccurate production of speech sounds in the absence of any etiology or communication impairment, on phonological awareness tasks. Investigators found that children with SSI scored below their typically developing peers (TD) on phonological awareness tasks. In contrast, others found no differences between groups. It seems likely that differences in findings regarding phonological awareness skills among children with SSI is the fact that there is considerable heterogeneity among children with SSI (i.e., speech errors can either be a phonological or articulation). Phonology is one component of a child's language system and a phonological impairment (SSI-PI) is evident when patterns of deviations of speech sounds are exhibited in a language system. Children with an articulation impairment (SSI-AI) produce speech sound errors that are affected by the movements of the articulators, not sound patterns. The purpose of the study was to examine whether or not children with SSI-PI are at greater risk for acquiring phonological awareness skills than children with SSI-AI. Furthermore, the phonological awareness skills of children with SSI-PI and SSI-AI were compared to those of their typical peers. In addition, the role of executive function as well as the influence of phonological working memory on phonological awareness task performance was examined.

Findings indicate that the SSI-PI group performed more poorly on an assessment of phonological awareness skills than the SSI-AI and TD groups. The SSI-PI group performed significantly more poorly on tasks of executive function and phonological working memory than the TD group. The results of this study support the hypothesis that children with SSI-PI may be more vulnerable to difficulties in reading than children with SSI-AI and children with TD.
ContributorsFox, Angela Marie (Author) / Wilcox, M. Jeanne (Thesis advisor) / Ingram, David (Committee member) / Gray, Shelley (Committee member) / Connor, Carol (Committee member) / Arizona State University (Publisher)
Created2015
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Description
This pilot study evaluated whether Story Champs and Puente de Cuentos helped bilingual preschoolers increase their usage of emotional terms and ability to tell stories. Participants in this study included 10 Spanish-English bilingual preschoolers. Intervention was conducted in 9 sessions over 3 days using the Test of Narrative Retell to

This pilot study evaluated whether Story Champs and Puente de Cuentos helped bilingual preschoolers increase their usage of emotional terms and ability to tell stories. Participants in this study included 10 Spanish-English bilingual preschoolers. Intervention was conducted in 9 sessions over 3 days using the Test of Narrative Retell to measure results. Results did not find significant gains in either emotional term usage or ability to tell stories, but the results were promising as a pilot study.
ContributorsSato, Leslie Mariko (Author) / Restrepo, Maria (Thesis director) / Dixon, Maria (Committee member) / Department of Speech and Hearing Science (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Description
Individuals with autism spectrum disorder (ASD) are known to show impairments in various domains of executive function (EF) such as behavioral flexibility or inhibitory control. Research suggests that EF impairment in adults with ASD may relate to ASD core symptoms, restrictive behaviors and social communication deficits. Mindfulness-based stress

Individuals with autism spectrum disorder (ASD) are known to show impairments in various domains of executive function (EF) such as behavioral flexibility or inhibitory control. Research suggests that EF impairment in adults with ASD may relate to ASD core symptoms, restrictive behaviors and social communication deficits. Mindfulness-based stress reduction (MBSR) has shown promise for improving EF abilities in neurotypical adults, but research has not explored its efficacy or neural mechanisms in adults with ASD. This pilot study examines the effects of an 8-week MBSR intervention on self-report measures of EF and resting-state functional connectivity in a sample of adults with ASD. Fifty-four participants were assigned either to an MBSR group (n = 29) or a social support group (n = 25). Executive function was measured using the BRIEF-2 before and after the intervention for the twenty-seven participants in the second cohort. MBSR-specific improvements in EF were found for BRIEF measures of initiation, inhibition, and working-memory. Resting-state fMRI data was analyzed using independent component analysis (ICA), and group by time resting-state functional connectivity differences were observed between the cerebellar network and frontal regions including the right frontal pole (rFP), medial frontal cortex (MFC) and left and right superior frontal gyri (SFG). The MBSR group showed increases in functional connectivity between the cerebellum and EF regions which correlated with improvements in BRIEF-2 measures. These findings suggest that MBSR may improve EF domains in adults with ASD, and that increases in functional connectivity between the cerebellum and frontal regions while at rest may be a mechanism for such improvements.
ContributorsGuerithault, Nicolas (Author) / Braden, B. Blair (Thesis advisor) / Rogalsky, Corianne (Committee member) / Dixon, Maria (Committee member) / Arizona State University (Publisher)
Created2021