This study examines the effectiveness of two modes of exercise on inhibitory control in adults with Down Syndrome (DS). Thirteen participants attended four sessions: a baseline assessment, an Assisted Cycling Therapy (ACT) session, a Resistance Training (RT) session, and a session of No Training (NT). In the baseline assessment, 1-repetition max (1RM) measurements and voluntary pedal rate measurements were taken. In the resistance training session, the leg press, chest press, seated row, leg curl, shoulder press, and latissimus pulldown were performed. In the cycling intervention, the participant completed 30 minutes of cycling. The Erikson Flanker task was administered prior to each session (i.e., pretest) and after the intervention (i.e., post-test). The results were somewhat consistent with the hypothesis that inhibition time improved more following RT and ACT than NT. there was also a significant difference between ACT and NT. Additionally, it was hypothesized that all measures would improve following each acute exercise intervention, but the most significant improvements were seen following ACT. In conclusion, an acute session of ACT demonstrated a significant trend towards improvements in inhibitory control in adults with DS which we interpreted using a model of neural changes.

The purpose of this study was to examine the validity of a modified Assisted Cycling Therapy bicycle for improving depression in children with Down Syndrome (DS). Seven participants completed 2x/week for 8 weeks, 30 minutes at a time of ACT, in which participants’ voluntary pedaling rates were augmented via the bicycle motor, ensuring that they were pedaling at a rate greater than their self-paced rate. Depression was measured using a modified version of the Children’s Depressive Inventory, called the CDI-2. Our study demonstrated that the scores from the CDI-2 decreased, demonstrating less depressive symptomatology after the conclusion of the 8 week intervention. Our results were interpreted via our model of the mechanisms involved in influencing the success of ACT. Future research would include a greater sample size, a more relevant measure of depressive scores, and a consistent data collection environment. However our initial pilot study showed promising results for improving mental health in children with DS.