Matching Items (2)
Filtering by

Clear all filters

157392-Thumbnail Image.png
Description
With a growing number of adults with autism spectrum disorder (ASD), more and more research has been conducted on majority male cohorts with ASD from young, adolescence, and some older age. Currently, males make up the majority of individuals diagnosed with ASD, however, recent research states that the gender ga

With a growing number of adults with autism spectrum disorder (ASD), more and more research has been conducted on majority male cohorts with ASD from young, adolescence, and some older age. Currently, males make up the majority of individuals diagnosed with ASD, however, recent research states that the gender gap is closing due to more advanced screening and a better understanding of how females with ASD present their symptoms. Little research has been published on the neurocognitive differences that exist between older adults with ASD compared to neurotypical (NT) counterparts, and nothing has specifically addressed older women with ASD. This study utilized neuroimaging and neuropsychological tests to examine differences between diagnosis and sex of four distinct groups: older men with ASD, older women with ASD, older NT men, and older NT women. In each group, hippocampal size (via FreeSurfer) was analyzed for differences as well as correlations with neuropsychological tests. Participants (ASD Female, n = 12; NT Female, n = 14; ASD Male, n = 30; NT Male = 22), were similar according to age, IQ, and education. The results of the study indicated that the ASD Group as a whole performed worse on executive functioning tasks (Wisconsin Card Sorting Test, Trails Making Test) and memory-related tasks (Rey Auditory Verbal Learning Test, Weschler Memory Scale: Visual Reproduction) compared to the NT Group. Interactions of sex by diagnosis approached significance only within the WCST non-perseverative errors, with the women with ASD performing worse than NT women, but no group differences between men. Effect sizes between the female groups (ASD female vs. NT female) showed more than double that of the male groups (ASD male vs. NT male) for all WCST and AVLT measures. Participants with ASD had significantly smaller right hippocampal volumes than NT participants. In addition, all older women showed larger hippocampal volumes when corrected for total intracranial volume (TIV) compared to all older men. Overall, NT Females had significant correlations across all neuropsychological tests and their hippocampal volumes whereas no other group had significant correlations. These results suggest a tighter coupling between hippocampal size and cognition in NT Females than NT Males and both sexes with ASD. This study promotes further understanding of the neuropsychological differences between older men and women, both with and without ASD. Further research is needed on a larger sample of older women with and without ASD.
ContributorsWebb, Christen Len (Author) / Braden, B. Blair (Thesis advisor) / Azuma, Tamiko (Committee member) / Dixon, Maria (Committee member) / Arizona State University (Publisher)
Created2019
156757-Thumbnail Image.png
Description
Dual language use is thought to afford certain cognitive advantages to bilingual children and may function as an additional resource to help low-income Mexican-American children achieve academically. Emotion regulation and executive functioning (e.g., inhibition) have been found to be particularly important in studies investigating pathways to early academic achievement. Understanding

Dual language use is thought to afford certain cognitive advantages to bilingual children and may function as an additional resource to help low-income Mexican-American children achieve academically. Emotion regulation and executive functioning (e.g., inhibition) have been found to be particularly important in studies investigating pathways to early academic achievement. Understanding how we can capitalize on children’s bilingual abilities to strengthen their executive functioning and emotion regulation, or to offset problems in these domains, may be important to promote better educational outcomes and inform policy. Thus, the current study investigated the relation between emerging bilingualism, inhibition, emotion regulation, and academic achievement across early childhood in sample of 322 low-income, Mexican-American children. Data were collected in a laboratory space at child ages 36-, 54-, and 72-months. Bilingualism was indexed as the interaction of Spanish and English vocabulary, and a mediated moderation model was examined. Results provided further evidence that inhibition positively predicts academic achievement during early childhood. Greater Spanish language vocabulary indirectly predicted academic achievement while controlling for English language vocabulary, suggesting that children from immigrant families may benefit from maintaining their Spanish language abilities as they begin to immerse themselves in an English-speaking classroom. Advancing our understanding of the development of self-regulatory abilities within bilingual, immigrant populations could have significant implications for educational policy.
ContributorsWinstone, Laura K (Author) / Crnic, Keith (Thesis advisor) / Gonzales, Nancy (Committee member) / Benitez, Viridiana (Committee member) / Arizona State University (Publisher)
Created2018