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The current study investigated whether intermittent restraint stress (IRS) would impair fear extinction learning and lead to increased anxiety and depressive- like behaviors and then be attenuated when IRS ends and a post- stress rest period ensues for 6 weeks. Young adult, male Sprague Dawley rats underwent restraint stress using

The current study investigated whether intermittent restraint stress (IRS) would impair fear extinction learning and lead to increased anxiety and depressive- like behaviors and then be attenuated when IRS ends and a post- stress rest period ensues for 6 weeks. Young adult, male Sprague Dawley rats underwent restraint stress using wire mesh (6hr/daily) for five days with two days off before restraint resumed for three weeks for a total of 23 restraint days. The groups consisted of control (CON) with no restraint other than food and water restriction yoked to the restrained groups, stress immediate (STR-IMM), which were restrained then fear conditioned soon after the end of the IRS paradigm, and stress given a rest for 6 weeks before fear conditioning commenced (STR-R6). Rats were fear conditioned by pairing a 20 second tone with a footshock, then given extinction training for two days (15 tone only on each day). On the first day of extinction, all groups discriminated well on the first trial, but then as trials progressed, STR-R6 discriminated between tone and context less than did CON. On the second day of extinction, STR- IMM froze more to context in the earlier trials than compared to STR-R6 and CON. As trials progressed STR-IMM and STR-R6 froze more to context than compared to CON. Together, CON discriminated between tone and context better than did STR-IMM and STR-R6. Sucrose preference, novelty suppressed feeding, and elevated plus maze was performed after fear extinction was completed. No statistical differences were observed among groups for sucrose preference or novelty suppressed feeding. For the elevated plus maze, STR-IMM entered the open arms and the sum of both open and closed arms fewer than did STR- R6 and CON. We interpret the findings to suggest that the stress groups displayed increased hypervigilance and anxiety with STR-R6 exhibiting a unique phenotype than that of STR-IMM and CON.
ContributorsShah, Vrishti Bimal (Author) / Conrad, Cheryl (Thesis director) / Newbern, Jason (Committee member) / Judd, Jessica (Committee member) / School of Life Sciences (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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An increasing number of military veterans are enrolling in college, primarily due to the Post-9/11 GI Bill, which provides educational benefits to veterans who served on active duty since September 11, 2001. With rigorous training, active combat situations, and exposure to unexpected situations, the veteran population is at a higher

An increasing number of military veterans are enrolling in college, primarily due to the Post-9/11 GI Bill, which provides educational benefits to veterans who served on active duty since September 11, 2001. With rigorous training, active combat situations, and exposure to unexpected situations, the veteran population is at a higher risk for traumatic brain injury (TBI), Post Traumatic Stress Disorder (PTSD), and depression. All of these conditions are associated with cognitive consequences, including attention deficits, working memory problems, and episodic memory impairments. Some conditions, particularly mild TBI, are not diagnosed or treated until long after the injury when the person realizes they have cognitive difficulties. Even mild cognitive problems can hinder learning in an academic setting, but there is little data on the frequency and severity of cognitive deficits in veteran college students. The current study examines self-reported cognitive symptoms in veteran students compared to civilian students and how those symptoms relate to service-related conditions. A better understanding of the pattern of self-reported symptoms will help researchers and clinicians determine the veterans who are at higher risk for cognitive and academic difficulties.
ContributorsAllen, Kelly Anne (Author) / Azuma, Tamiko (Thesis director) / Gallagher, Karen (Committee member) / Department of Speech and Hearing Science (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description

The Cambodian-Vietnamese War, beginning in the late 1970s, was largely influenced by differing political ideologies among people and organizations in both Cambodia and Vietnam, as well as the United States and China. The war over communism, socialism, and democracy helped give rise to groups such as the Communist Party of

The Cambodian-Vietnamese War, beginning in the late 1970s, was largely influenced by differing political ideologies among people and organizations in both Cambodia and Vietnam, as well as the United States and China. The war over communism, socialism, and democracy helped give rise to groups such as the Communist Party of Kampuchea or Khmer Rouge in Cambodia. In 1977 and 1978, the Khmer Rouge attacked Vietnam, killing thousands of people in the process. In the aftermath of the war, various social implications occurred in Cambodia and Vietnam. Many who lived through the war, whether soldiers or civilians, were left traumatized and suffered from PTSD. Fighting resulted in large refugee communities and conscription by the respective states meant that most people in these countries were directly touched by war. Vietnam’s occupation of Cambodia and the strained relationships in the region caused lasting consequences. These societal implications can still be seen today, and the Cambodian-Vietnamese War can be a reminder of the devastating consequences of war and political conflict.

ContributorsDa Rosa, Alexandra (Author) / Niebuhr, Robert (Thesis director) / Le, Andrew (Committee member) / Barrett, The Honors College (Contributor) / Sanford School of Social and Family Dynamics (Contributor)
Created2023-05
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Posttraumatic stress disorder is a psychiatric disorder that can develop after exposure to a traumatic event, and it can cause affected individuals to relive the associated event through flashbacks or nightmares. This project centers around the prevalence of PTSD in parents of infants admitted to the neonatal intensive care unit.

Posttraumatic stress disorder is a psychiatric disorder that can develop after exposure to a traumatic event, and it can cause affected individuals to relive the associated event through flashbacks or nightmares. This project centers around the prevalence of PTSD in parents of infants admitted to the neonatal intensive care unit. Past research has shown that these parents are at increased risk of developing traumatic stress symptoms, with affliction rates as high as 53% in mothers and 33% in fathers (Hua et al., 2018). With this statistic as a catalyst, the present text has a variety of aims, all hinging on the goal of easing the NICU journey for parents. This thesis explores the different types of therapy used in the treatment of traumatic stress, with a focus on trauma-focused cognitive behavioral therapy (TF-CBT) and eye movement desensitization and reprocessing (EMDR) as these were shown to be the most effective in past research. A compilation of resources was also gathered that can now be distributed to NICU parents, including information on PTSD, how to access a therapist, and other helpful articles. An additional component of this project included the administration of a survey to NICU parents to gain a better understanding of their stress levels, what resources were most helpful to them, what barriers limited their ability to seek help, and their thoughts on a text-messaging resource service. Institutional IRB approval was received for this survey. The survey indicated that parents were very stressed when admitted to the NICU, but their stress levels tend to decrease over time. Parents also faced a variety of barriers, with the need to return to work or maintain a busy schedule being the most pervasive. Additionally, an analysis was completed on federal legislation relating to healthcare and the NICU experience. Furthermore, special considerations for limited English proficient (LEP) families were also considered. The paper concludes with steps that should be taken, in both research and action, to improve on the NICU experience for at-risk parents. The implementation of a text-messaging resource service for NICU parents was desired by survey respondents and is a recommended next step. Changes in policy surrounding insurance reform and longer, paid family leave would also be beneficial. Training of NICU staff on how to provide resources and communicate sensitively and effectively with parents is also crucial if the current situation is to be improved. There are definitive steps that should be taken immediately to ease the journey and provide comfort for NICU parents.
ContributorsBryant, Tyler (Co-author) / Beck, Kelsey (Co-author) / Puruhito, Krista (Thesis director) / Visconti, Kari (Committee member) / Historical, Philosophical & Religious Studies (Contributor) / School of Politics and Global Studies (Contributor, Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05