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Human walking has been a highly studied topic in research communities because of its extreme importance to human functionality and mobility. A complex system of interconnected gait mechanisms in humans is responsible for generating robust and consistent walking motion over unpredictable ground and through challenging obstacles. One interesting aspect of

Human walking has been a highly studied topic in research communities because of its extreme importance to human functionality and mobility. A complex system of interconnected gait mechanisms in humans is responsible for generating robust and consistent walking motion over unpredictable ground and through challenging obstacles. One interesting aspect of human gait is the ability to adjust in order to accommodate varying surface grades. Typical approaches to investigating this gait function focus on incline and decline surface angles, but most experiments fail to address the effects of surface grades that cause ankle inversion and eversion. There have been several studies of ankle angle perturbation over wider ranges of grade orientations in static conditions; however, these studies do not account for effects during the gait cycle. Furthermore, contemporary studies on this topic neglect critical sources of unnatural stimulus in the design of investigative technology. It is hypothesized that the investigation of ankle angle perturbations in the frontal plane, particularly in the context of inter-leg coordination mechanisms, results in a more complete characterization of the effects of surface grade on human gait mechanisms. This greater understanding could potentially lead to significant applications in gait rehabilitation, especially for individuals who suffer from impairment as a result of stroke. A wearable pneumatic device was designed to impose inversion and eversion perturbations on the ankle through simulated surface grade changes. This prototype device was fabricated, characterized, and tested in order to assess its effectiveness. After testing and characterizing this device, it was used in a series of experiments on human subjects while data was gathered on muscular activation and gait kinematics. The results of the characterization show success in imposing inversion and eversion angle perturbations of approximately 9° with a response time of 0.5 s. Preliminary experiments focusing on inter-leg coordination with healthy human subjects show that one-sided inversion and eversion perturbations have virtually no effect on gait kinematics. However, changes in muscular activation from one-sided perturbations show statistical significance in key lower limb muscles. Thus, the prototype device demonstrates novelty in the context of human gait research for potential applications in rehabilitation.
ContributorsBarkan, Andrew (Author) / Artemiadis, Panagiotis (Thesis advisor) / Lee, Hyunglae (Committee member) / Marvi, Hamidreza (Committee member) / Arizona State University (Publisher)
Created2016
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Description
The human ankle is a vital joint in the lower limb of the human body. As the point of interaction between the human neuromuscular system and the physical world, the ankle plays important role in lower extremity functions including postural balance and locomotion . Accurate characterization of ankle mechanics in

The human ankle is a vital joint in the lower limb of the human body. As the point of interaction between the human neuromuscular system and the physical world, the ankle plays important role in lower extremity functions including postural balance and locomotion . Accurate characterization of ankle mechanics in lower extremity function is essential not just to advance the design and control of robots physically interacting with the human lower extremities but also in rehabilitation of humans suffering from neurodegenerative disorders.

In order to characterize the ankle mechanics and understand the underlying mechanisms that influence the neuromuscular properties of the ankle, a novel multi-axial robotic platform was developed. The robotic platform is capable of simulating various haptic environments and transiently perturbing the ankle to analyze the neuromechanics of the ankle, specifically the ankle impedance. Humans modulate ankle impedance to perform various tasks of the lower limb. The robotic platform is used to analyze the modulation of ankle impedance during postural balance and locomotion on various haptic environments. Further, various factors that influence modulation of ankle impedance were identified. Using the factors identified during environment dependent impedance modulation studies, the quantitative relationship between these factors, namely the muscle activation of major ankle muscles, the weight loading on ankle and the torque generation at the ankle was analyzed during postural balance and locomotion. A universal neuromuscular model of the ankle that quantitatively relates ankle stiffness, the major component of ankle impedance, to these factors was developed.

This neuromuscular model is then used as a basis to study the alterations caused in ankle behavior due to neurodegenerative disorders such as Multiple Sclerosis and Stroke. Pilot studies to validate the analysis of altered ankle behavior and demonstrate the effectiveness of robotic rehabilitation protocols in addressing the altered ankle behavior were performed. The pilot studies demonstrate that the altered ankle mechanics can be quantified in the affected populations and correlate with the observed adverse effects of the disability. Further, robotic rehabilitation protocols improve ankle control in affected populations as seen through functional improvements in postural balance and locomotion, validating the neuromuscular approach for rehabilitation.
ContributorsNalam, Varun (Author) / Lee, Hyunglae (Thesis advisor) / Artemiadis, Panagiotis (Committee member) / Santello, Marco (Committee member) / Sugar, Thomas (Committee member) / Lockhart, Thurmon (Committee member) / Arizona State University (Publisher)
Created2020
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Description
Advancements in the field of design and control of lower extremity robotics requires a comprehensive understanding of the underlying mechanics of the human ankle. The ankle joint acts as an essential interface between the neuromuscular system of the body and the physical world, especially during locomotion. This paper investigates how

Advancements in the field of design and control of lower extremity robotics requires a comprehensive understanding of the underlying mechanics of the human ankle. The ankle joint acts as an essential interface between the neuromuscular system of the body and the physical world, especially during locomotion. This paper investigates how the modulation of ankle stiffness is altered throughout the stance phase of the gait cycle depending on the environment the ankle is interacting with. Ten young healthy subjects with no neurological impairments or history of ankle injury were tested by walking over a robotic platform which collected torque and position data. The platform performed a perturbation on the ankle at 20%, 40%, and 60% of their stance phase in order to estimate ankle stiffness and evaluate if the environment plays a role on its modulation. The platform provided either a rigid environment or a compliant environment in which it was compliant and deflected according to the torque applied to the platform. Subjects adapted in different ways to achieve balance in the different environments. When comparing the environments, subjects modulated their stiffness to either increase, decrease, or remain the same. Notably, stiffness as well as the subjects’ center of pressure was found to increase with time as they transitioned from late loading to terminal stance (heel strike to toe-off) regardless of environmental conditions. This allowed for a model of ankle stiffness to be developed as a function of center of pressure, independent of whether a subject is walking on the rigid or compliant environment. The modulation of stiffness parameters characterized in this study can be used in the design and control of lower extremity robotics which focus on accurate biomimicry of the healthy human ankle. The stiffness characteristics can also be used to help identify particular ankle impairments and to design proper treatment for individuals such as those who have suffered from a stroke or MS. Changing environments is where a majority of tripping incidents occur, which can lead to significant injuries. For this reason, studying healthy ankle behavior in a variety of environments is of particular interest.
ContributorsBliss, Clayton F (Author) / Lee, Hyunglae (Thesis director) / Marvi, Hamid (Committee member) / Mechanical and Aerospace Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description

The concept of entrainment broadly applies the locking of phases between 2 independent systems [17]. This physical phenomenon can be applied to modify neuromuscular movement in humans during bipedal locomotion. Gait entrainment to robotic devices have shown great success as alternatives to labor intensive methods of rehabilitation. By applying additional

The concept of entrainment broadly applies the locking of phases between 2 independent systems [17]. This physical phenomenon can be applied to modify neuromuscular movement in humans during bipedal locomotion. Gait entrainment to robotic devices have shown great success as alternatives to labor intensive methods of rehabilitation. By applying additional torque at the ankle joint, previous studies have exhibited consistent gait entrainment to both rigid and soft robotic devices. This entrainment is characterized by consistent phase locking of plantarflexion perturbations to the ‘push off’ event within the gait cycle. However, it is unclear whether such phase locking can be attributed to the plantarflexion assistance from the device or the sensory stimulus of movement at the ankle. To clarify the mechanism of entrainment, an experiment was designed to expose the user to a multitude of varying torques applied at the ankle to assist with plantar flexion. In this experiment, no significant difference in success of subject entrainment occurred when additional torque applied was greater than a detectable level. Force applied at the ankle varied from ~60N to ~130N. This resulted in successful entrainment ~88\% of the time at 98 N, with little to no increase in success as force increased thereafter. Alternatively, success of trials decreased significantly as force was reduced below this level, causing the perturbations to become undetectable by participants. Ultimately this suggests that higher levels of actuator pressure, and thus greater levels of torque applied to the foot, do not increase the likelihood of entrainment during walking. Rather, the results of this study suggest that proper detectable sensory stimulus is the true mechanism for entrainment.

ContributorsKruse, Anna (Author) / Lee, Hyunglae (Thesis director) / Berman, Spring (Committee member) / Barrett, The Honors College (Contributor) / Mechanical and Aerospace Engineering Program (Contributor)
Created2022-12