Matching Items (8)
Description
Spinal cord injury (SCI) disrupts the communication between supraspinal circuits and spinal circuits distal to the injury. This disruption causes changes in the motor abilities of the affected individual, but it can also be used as an opportunity to study motor control in the absence or limited presence of control from the brain. In the case of incomplete paraplegia, locomotion is impaired and often results in increased incidence of foot drag and decreased postural stability after injury. The overall goal of this work is to understand how changes in kinematics of movement and neural control of muscles effect locomotor coordination following SCI. Toward this end, we examined musculoskeletal parameters and kinematics of gait in rats with and without incomplete SCI (iSCI) and used an empirically developed computational model to test related hypotheses. The first study tested the hypothesis that iSCI causes a decrease in locomotor and joint angle movement complexity. A rat model was used to measure musculoskeletal properties and gait kinematics following mild iSCI. The data indicated joint-specific changes in kinematics in the absence of measurable muscle atrophy, particularly at the ankle as a result of the injury. Kinematic changes manifested as a decrease in complexity of ankle motion as indicated by measures of permutation entropy. In the second study, a new 2-dimensional computational model of the rat ankle combining forward and inverse dynamics was developed using the previously collected data. This model was used to test the hypothesis that altered coordination of flexor and extensor muscles (specifically alteration in burst shape and timing) acting at the ankle joint could be responsible for increases in incidence of foot drag following injury. Simulation results suggest a time course for changes in neural control following injury that begins with foot drag and decreased delay between antagonistic muscle activations. Following this, beneficial adaptations in muscle activation profile and ankle kinematics counteract the decreased delay to allow foot swing. In both studies, small changes in neural control caused large changes in behavior, particularly at the ankle. Future work will further examine the role of neural control of hindlimb in rat locomotion following iSCI.
ContributorsHillen, Brian (Author) / Jung, Ranu (Thesis advisor) / Abbas, James (Committee member) / Muthuswamy, Jit (Committee member) / Jindrich, Devin (Committee member) / Yamaguchi, Gary (Committee member) / Arizona State University (Publisher)
Created2012
Description
Approximately 1.7 million people in the United States are living with limb loss and are in need of more sophisticated devices that better mimic human function. In the Human Machine Integration Laboratory, a powered, transtibial prosthetic ankle was designed and build that allows a person to regain ankle function with improved ankle kinematics and kinetics. The ankle allows a person to walk normally and up and down stairs, but volitional control is still an issue. This research tackled the problem of giving the user more control over the prosthetic ankle using a force/torque circuit. When the user presses against a force/torque sensor located inside the socket the prosthetic foot plantar flexes or moves downward. This will help the user add additional push-off force when walking up slopes or stairs. It also gives the user a sense of control over the device.
ContributorsFronczyk, Adam (Author) / Sugar, Thomas G. (Thesis advisor) / Helms-Tillery, Stephen (Thesis advisor) / Santello, Marco (Committee member) / Arizona State University (Publisher)
Created2012
Description
In this work, different passive prosthetic ankles are studied. It is observed that complicated designs increase the cost of production, but simple designs have limited functionality. A new design for a passive prosthetic ankle is presented that is simple to manufacture while having superior functionality. This prosthetic ankle design has two springs: one mimicking Achilles tendon and the other mimicking Anterior-Tibialis tendon. The dynamics of the prosthetic ankle is discussed and simulated using Working model 2D. The simulation results are used to optimize the springs stiffness. Two experiments are conducted using the developed ankle to verify the simulation It is found that this novel ankle design is better than Solid Ankle Cushioned Heel (SACH) foot. The experimental data is used to find the tendon and muscle activation forces of the subject wearing the prosthesis using OpenSim. A conclusion is included along with suggested future work.
ContributorsBhat, Sandesh Ganapati (Author) / Redkar, Sangram (Thesis advisor) / Sugar, Thomas (Committee member) / Lee, Hyuglae (Committee member) / Marvi, Hamid (Committee member) / Arizona State University (Publisher)
Created2017
Description
Human walking has been a highly studied topic in research communities because of its extreme importance to human functionality and mobility. A complex system of interconnected gait mechanisms in humans is responsible for generating robust and consistent walking motion over unpredictable ground and through challenging obstacles. One interesting aspect of human gait is the ability to adjust in order to accommodate varying surface grades. Typical approaches to investigating this gait function focus on incline and decline surface angles, but most experiments fail to address the effects of surface grades that cause ankle inversion and eversion. There have been several studies of ankle angle perturbation over wider ranges of grade orientations in static conditions; however, these studies do not account for effects during the gait cycle. Furthermore, contemporary studies on this topic neglect critical sources of unnatural stimulus in the design of investigative technology. It is hypothesized that the investigation of ankle angle perturbations in the frontal plane, particularly in the context of inter-leg coordination mechanisms, results in a more complete characterization of the effects of surface grade on human gait mechanisms. This greater understanding could potentially lead to significant applications in gait rehabilitation, especially for individuals who suffer from impairment as a result of stroke. A wearable pneumatic device was designed to impose inversion and eversion perturbations on the ankle through simulated surface grade changes. This prototype device was fabricated, characterized, and tested in order to assess its effectiveness. After testing and characterizing this device, it was used in a series of experiments on human subjects while data was gathered on muscular activation and gait kinematics. The results of the characterization show success in imposing inversion and eversion angle perturbations of approximately 9° with a response time of 0.5 s. Preliminary experiments focusing on inter-leg coordination with healthy human subjects show that one-sided inversion and eversion perturbations have virtually no effect on gait kinematics. However, changes in muscular activation from one-sided perturbations show statistical significance in key lower limb muscles. Thus, the prototype device demonstrates novelty in the context of human gait research for potential applications in rehabilitation.
ContributorsBarkan, Andrew (Author) / Artemiadis, Panagiotis (Thesis advisor) / Lee, Hyunglae (Committee member) / Marvi, Hamidreza (Committee member) / Arizona State University (Publisher)
Created2016
Description
The human ankle is a vital joint in the lower limb of the human body. As the point of interaction between the human neuromuscular system and the physical world, the ankle plays important role in lower extremity functions including postural balance and locomotion . Accurate characterization of ankle mechanics in lower extremity function is essential not just to advance the design and control of robots physically interacting with the human lower extremities but also in rehabilitation of humans suffering from neurodegenerative disorders.
In order to characterize the ankle mechanics and understand the underlying mechanisms that influence the neuromuscular properties of the ankle, a novel multi-axial robotic platform was developed. The robotic platform is capable of simulating various haptic environments and transiently perturbing the ankle to analyze the neuromechanics of the ankle, specifically the ankle impedance. Humans modulate ankle impedance to perform various tasks of the lower limb. The robotic platform is used to analyze the modulation of ankle impedance during postural balance and locomotion on various haptic environments. Further, various factors that influence modulation of ankle impedance were identified. Using the factors identified during environment dependent impedance modulation studies, the quantitative relationship between these factors, namely the muscle activation of major ankle muscles, the weight loading on ankle and the torque generation at the ankle was analyzed during postural balance and locomotion. A universal neuromuscular model of the ankle that quantitatively relates ankle stiffness, the major component of ankle impedance, to these factors was developed.
This neuromuscular model is then used as a basis to study the alterations caused in ankle behavior due to neurodegenerative disorders such as Multiple Sclerosis and Stroke. Pilot studies to validate the analysis of altered ankle behavior and demonstrate the effectiveness of robotic rehabilitation protocols in addressing the altered ankle behavior were performed. The pilot studies demonstrate that the altered ankle mechanics can be quantified in the affected populations and correlate with the observed adverse effects of the disability. Further, robotic rehabilitation protocols improve ankle control in affected populations as seen through functional improvements in postural balance and locomotion, validating the neuromuscular approach for rehabilitation.
In order to characterize the ankle mechanics and understand the underlying mechanisms that influence the neuromuscular properties of the ankle, a novel multi-axial robotic platform was developed. The robotic platform is capable of simulating various haptic environments and transiently perturbing the ankle to analyze the neuromechanics of the ankle, specifically the ankle impedance. Humans modulate ankle impedance to perform various tasks of the lower limb. The robotic platform is used to analyze the modulation of ankle impedance during postural balance and locomotion on various haptic environments. Further, various factors that influence modulation of ankle impedance were identified. Using the factors identified during environment dependent impedance modulation studies, the quantitative relationship between these factors, namely the muscle activation of major ankle muscles, the weight loading on ankle and the torque generation at the ankle was analyzed during postural balance and locomotion. A universal neuromuscular model of the ankle that quantitatively relates ankle stiffness, the major component of ankle impedance, to these factors was developed.
This neuromuscular model is then used as a basis to study the alterations caused in ankle behavior due to neurodegenerative disorders such as Multiple Sclerosis and Stroke. Pilot studies to validate the analysis of altered ankle behavior and demonstrate the effectiveness of robotic rehabilitation protocols in addressing the altered ankle behavior were performed. The pilot studies demonstrate that the altered ankle mechanics can be quantified in the affected populations and correlate with the observed adverse effects of the disability. Further, robotic rehabilitation protocols improve ankle control in affected populations as seen through functional improvements in postural balance and locomotion, validating the neuromuscular approach for rehabilitation.
ContributorsNalam, Varun (Author) / Lee, Hyunglae (Thesis advisor) / Artemiadis, Panagiotis (Committee member) / Santello, Marco (Committee member) / Sugar, Thomas (Committee member) / Lockhart, Thurmon (Committee member) / Arizona State University (Publisher)
Created2020
Description
The mean age of the world’s population is rapidly increasing and with that growth in an aging population a large number of elderly people are in need of walking assistance. In addition, a number of medical conditions contribute to gait disorders that require gait rehabilitation. Wearable robotics can be used to improve functional outcomes in the gait rehabilitation process. The ankle push-off phase of an individual’s gait is vital to their ability to walk and propel themselves forward. During the ankle push-off phase of walking, plantar flexors are required to providing a large amount of force to power the heel off the ground.
The purpose of this project is to improve upon the passive ankle foot orthosis originally designed in the ASU’s Robotics and Intelligent Systems Laboratory (RISE Lab). This device utilizes springs positioned parallel to the user’s Achilles tendon which store energy to be released during the push off phase of the user’s gait cycle. Goals of the project are to improve the speed and reliability of the ratchet and pawl mechanism, design the device to fit a wider range of shoe sizes, and reduce the overall mass and size of the device. The resulting system is semi-passive and only utilizes a single solenoid to unlock the ratcheting mechanism when the spring’s potential force is required. The device created also utilizes constant force springs rather than traditional linear springs which allows for a more predictable level of force. A healthy user tested the device on a treadmill and surface electromyography (sEMG) sensors were placed on the user’s plantar flexor muscles to monitor potential reductions in muscular activity resulting from the assistance provided by the AFO device. The data demonstrates the robotic shoe was able to assist during the heel-off stage and reduced activation in the plantar flexor muscles was evident from the EMG data collected. As this is an ongoing research project, this thesis will also recommend possible design upgrades and changes to be made to the device in the future. These upgrades include utilizing a carbon fiber or lightweight plastic frame such as many of the traditional ankle foot-orthosis sold today and introducing a system to regulate the amount of spring force applied as a function of the force required at specific times of the heel off gait phase.
The purpose of this project is to improve upon the passive ankle foot orthosis originally designed in the ASU’s Robotics and Intelligent Systems Laboratory (RISE Lab). This device utilizes springs positioned parallel to the user’s Achilles tendon which store energy to be released during the push off phase of the user’s gait cycle. Goals of the project are to improve the speed and reliability of the ratchet and pawl mechanism, design the device to fit a wider range of shoe sizes, and reduce the overall mass and size of the device. The resulting system is semi-passive and only utilizes a single solenoid to unlock the ratcheting mechanism when the spring’s potential force is required. The device created also utilizes constant force springs rather than traditional linear springs which allows for a more predictable level of force. A healthy user tested the device on a treadmill and surface electromyography (sEMG) sensors were placed on the user’s plantar flexor muscles to monitor potential reductions in muscular activity resulting from the assistance provided by the AFO device. The data demonstrates the robotic shoe was able to assist during the heel-off stage and reduced activation in the plantar flexor muscles was evident from the EMG data collected. As this is an ongoing research project, this thesis will also recommend possible design upgrades and changes to be made to the device in the future. These upgrades include utilizing a carbon fiber or lightweight plastic frame such as many of the traditional ankle foot-orthosis sold today and introducing a system to regulate the amount of spring force applied as a function of the force required at specific times of the heel off gait phase.
ContributorsSchaller, Marcus Frank (Author) / Zhang, Wenlong (Thesis director) / Sugar, Thomas (Committee member) / Engineering Programs (Contributor) / Barrett, The Honors College (Contributor)
Created2019-12
Description
Advancements in the field of design and control of lower extremity robotics requires a comprehensive understanding of the underlying mechanics of the human ankle. The ankle joint acts as an essential interface between the neuromuscular system of the body and the physical world, especially during locomotion. This paper investigates how the modulation of ankle stiffness is altered throughout the stance phase of the gait cycle depending on the environment the ankle is interacting with. Ten young healthy subjects with no neurological impairments or history of ankle injury were tested by walking over a robotic platform which collected torque and position data. The platform performed a perturbation on the ankle at 20%, 40%, and 60% of their stance phase in order to estimate ankle stiffness and evaluate if the environment plays a role on its modulation. The platform provided either a rigid environment or a compliant environment in which it was compliant and deflected according to the torque applied to the platform. Subjects adapted in different ways to achieve balance in the different environments. When comparing the environments, subjects modulated their stiffness to either increase, decrease, or remain the same. Notably, stiffness as well as the subjects’ center of pressure was found to increase with time as they transitioned from late loading to terminal stance (heel strike to toe-off) regardless of environmental conditions. This allowed for a model of ankle stiffness to be developed as a function of center of pressure, independent of whether a subject is walking on the rigid or compliant environment. The modulation of stiffness parameters characterized in this study can be used in the design and control of lower extremity robotics which focus on accurate biomimicry of the healthy human ankle. The stiffness characteristics can also be used to help identify particular ankle impairments and to design proper treatment for individuals such as those who have suffered from a stroke or MS. Changing environments is where a majority of tripping incidents occur, which can lead to significant injuries. For this reason, studying healthy ankle behavior in a variety of environments is of particular interest.
ContributorsBliss, Clayton F (Author) / Lee, Hyunglae (Thesis director) / Marvi, Hamid (Committee member) / Mechanical and Aerospace Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The concept of entrainment broadly applies the locking of phases between 2 independent systems [17]. This physical phenomenon can be applied to modify neuromuscular movement in humans during bipedal locomotion. Gait entrainment to robotic devices have shown great success as alternatives to labor intensive methods of rehabilitation. By applying additional torque at the ankle joint, previous studies have exhibited consistent gait entrainment to both rigid and soft robotic devices. This entrainment is characterized by consistent phase locking of plantarflexion perturbations to the ‘push off’ event within the gait cycle. However, it is unclear whether such phase locking can be attributed to the plantarflexion assistance from the device or the sensory stimulus of movement at the ankle. To clarify the mechanism of entrainment, an experiment was designed to expose the user to a multitude of varying torques applied at the ankle to assist with plantar flexion. In this experiment, no significant difference in success of subject entrainment occurred when additional torque applied was greater than a detectable level. Force applied at the ankle varied from ~60N to ~130N. This resulted in successful entrainment ~88\% of the time at 98 N, with little to no increase in success as force increased thereafter. Alternatively, success of trials decreased significantly as force was reduced below this level, causing the perturbations to become undetectable by participants. Ultimately this suggests that higher levels of actuator pressure, and thus greater levels of torque applied to the foot, do not increase the likelihood of entrainment during walking. Rather, the results of this study suggest that proper detectable sensory stimulus is the true mechanism for entrainment.
ContributorsKruse, Anna (Author) / Lee, Hyunglae (Thesis director) / Berman, Spring (Committee member) / Barrett, The Honors College (Contributor) / Mechanical and Aerospace Engineering Program (Contributor)
Created2022-12