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The global population over the age of 60 is estimated to rise to 23% by 2050 only increase the prevalence of functional neurological disorders and stroke. Increase in cases of functional neurological disorders and strokes will place a greater burden on the healthcare industry, specifically physical therapy. Physical therapy is

The global population over the age of 60 is estimated to rise to 23% by 2050 only increase the prevalence of functional neurological disorders and stroke. Increase in cases of functional neurological disorders and strokes will place a greater burden on the healthcare industry, specifically physical therapy. Physical therapy is vital for a patient’s recovery of motor function which is time demanding and taxing on the physical therapist. Wearable robotics have been proven to improve functional outcomes in gait rehabilitation by providing controlled high dosage and high-intensity training. Accurate control strategies for assistive robotic exoskeletons are vital for repetitive high precisions assistance for cerebral plasticity to occur.

This thesis presents a preliminary determination and design of a control algorithm for an assistive ankle device developed by the ASU RISE Laboratory. The assistive ankle device functions by compressing a spring upon heel strike during gait, remaining compressed during mid-stance and then releasing upon initiation of heel-off. The relationship between surface electromyography and ground reactions forces were used for identification of user-initiated heel-off. The muscle activation of the tibialis anterior combined with the ground reaction forces of the heel pressure sensor generated potential features that will be utilized in the revised control algorithm for the assistive ankle device. Work on this project must proceed in order to test and validate the revised control algorithm to determine its accuracy and precision.
ContributorsGaytan-Jenkins, Daniel Rinaldo (Author) / Zhang, Wenlong (Thesis director) / Tyler, Jamie (Committee member) / Harrington Bioengineering Program (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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The research being proposed would develop an objective test for handedness analyzing circle-drawing movements performed with the dominant arm versus non-dominant arm. Handedness is a unique and exceptional characteristic of human beings which impacts society on an individual basis that has far-reaching influence. Its correlation and possible causation has been

The research being proposed would develop an objective test for handedness analyzing circle-drawing movements performed with the dominant arm versus non-dominant arm. Handedness is a unique and exceptional characteristic of human beings which impacts society on an individual basis that has far-reaching influence. Its correlation and possible causation has been studied and implied in everything from mental disorders (Deep-Soboslay et al. 2010) to advanced biological processes (Driscoll, Kei, & McPherson, 2002). Despite the importance of handedness, there are many faults surrounding the widely used methods for determining and classifying handedness. The most common of these, the Edinburgh Handedness Inventory, especially suffers from reporter bias, possibly confusing categories and instructions, and underestimating ambidextrous or mixed handedness. Research done by R.L. Sainburg of Penn State and N. Dounskaia of Arizona State University points to a possible method of measuring handedness. The findings of these studies show show that the dominant arm to perform better in drawing movements than the non-dominant arm. It is proposed that an objective test could be developed for handedness using circle-drawing tasks. A participant would draw circles with both arms, these movements would be analyzed to show which arm was dominant by showing which arm made the more perfect circle. By developing an objective test, handedness could be more properly classified and assessed, helping aid research and understanding in how handedness affects humans.
ContributorsKleisler, Kevin C. (Author) / Dounskaia, Natalia (Thesis director) / Ringenbach, Shannon (Committee member) / Wang, Wanyue (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2013-12
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Although the sport and exercise of running has a great amount of benefits to anyone's health, there is a chance of injury that can occur. There are many variables that can contribute to running injury. However, because of the vast amount of footsteps a frequent runner takes during their average

Although the sport and exercise of running has a great amount of benefits to anyone's health, there is a chance of injury that can occur. There are many variables that can contribute to running injury. However, because of the vast amount of footsteps a frequent runner takes during their average run, foot strike pattern is a significant factor to be investigated in running injury research. This study hypothesized that due to biomechanical factors, runners that exhibited a rear foot striking pattern would display a greater incidence of chronic lower extremity injury in comparison to forefoot striking counterparts. This hypothesis would support previous studies conducted on the topic. Student-athletes in the Arizona State University- Men's and Women's Track & Field program, specifically those who compete in distance events, were given self reporting surveys to provide injury history and had their foot strike patterns analyzed through video recordings. The survey and analysis of foot strike patterns resulted in data that mostly followed the hypothesized pattern of mid-foot and forefoot striking runners displaying a lower average frequency of injury in comparison to rear foot strikers. The differences in these averages across all injury categories was found to be statistically significant. One category that displayed the most supportive results was in the average frequency of mild injury. This lead to the proposed idea that while foot strike patterns may not be the best predictor of moderate and severe injuries, they may play a greater role in the origin of mild injury. Such injuries can be the gateway to more serious injury (moderate and severe) that are more likely to have their cause in other sources such as genetics or body composition for example. This study did support the idea that foot strike pattern can be the main predictor in incidence of running injuries, but also displayed that it is one of many major factors that contribute to injuries in runners.
ContributorsBaker-Slama, Garrett Richard (Author) / Harper, Erin (Thesis director) / Cataldo, Donna (Committee member) / Wilson, Jeffrey (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2014-05
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Description
Given the importance of arm mechanics in sprinting and the utility of F-V profiles, the purpose of the following study was to determine the effects of forearm WR on the horizontal F-V profile during sprinting. To determine the effect of forearm WR on the horizontal F-V profile during sprinting, a

Given the importance of arm mechanics in sprinting and the utility of F-V profiles, the purpose of the following study was to determine the effects of forearm WR on the horizontal F-V profile during sprinting. To determine the effect of forearm WR on the horizontal F-V profile during sprinting, a cross-sectional, repeated measure within subjects design was used, with athletes assessed both with and without forearm WR. The WR condition used 2% BM attached to the forearms. In a randomized order, subjects performed a series of maximal effort 30 m sprints; two unloaded sprints and four with WR. Three sprints were executed from a block start: one unloaded, and two with WR. The additional three sprints were executed from a split-stance start: one unloaded and two with WR. From this study, 2%BM WR was found to significantly increase sprint times from both block and standing starts. It also significantly decreased V0 and Fsystem from a block start and Psystem from a standing start. The significance from a block start may imply the arm’s greater role during the start and acceleration phases of sprinting during that position. The overloading of V0 from a block start in the F-V profile points to forearm WR as a possible tool for athletes to use during training who are overly force dominant from a block start and need to shift their profile to V0 dominance or balance in general.
ContributorsMishra, Megna (Author) / Nolan, Nicole (Thesis director) / Feser, Erin (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Description
Research on joint control during arm movements in adults has led to the development of the Leading Joint Hypothesis (LJH), which states that the central nervous system takes advantage of interaction torque (IT) and muscle torque (MT) to produce movements with maximum efficiency in the multi-jointed limbs of the human

Research on joint control during arm movements in adults has led to the development of the Leading Joint Hypothesis (LJH), which states that the central nervous system takes advantage of interaction torque (IT) and muscle torque (MT) to produce movements with maximum efficiency in the multi-jointed limbs of the human body. A gap in knowledge exists in determining how this mature pattern of joint control develops in children. Prior research focused on the kinematics of joint control for children below the age of three; however, not much is known about interjoint coordination with respect to MT and IT in school-aged children. In the present study, joint control at the shoulder, elbow, and wrist during drawing of five shapes was investigated. A random sample of nine typically developing children ages 6 to 12 served as subjects. The task was to trace with the index finger a template placed on a horizontal table. The template consisted of a circle, horizontal, vertical, right-diagonal, and left-diagonal line. Analysis of muscle torque contribution (MTC) revealed the individual roles of MT and IT in the shoulder, elbow, and wrist joints. During drawing of the horizontal line, which requires the most difficult joint control pattern in adults because it does not allow the use of IT for joint rotation, joint control was found to change through development. For the youngest children, the function of elbow MT modified to suppress IT, thereby producing large elbow rotation. The oldest children simplified this by using the shoulder as the principal joint of movement production and with decreased assistance from the elbow. For the other four drawing movements, differences in the pattern of joint control used by all of the subjects was unaffected by an increase in age. Overall, the results suggest that in children above 6 years of age, minor changes in joint control occur during drawing of relatively simple movements. The limited effect of age that was observed could be related to the restriction of movements to the horizontal plane. For a future study, three-dimensional movements that provide more freedom in joint control due to redundancy of degrees of freedom could be more informative about developmental changes in joint coordination.
ContributorsKemmou, Nadaa (Co-author) / Way, Victoria (Co-author) / Dounskaia, Natalia (Thesis director) / Vidt, Meghan (Committee member) / School of Nutrition and Health Promotion (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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Description
With dwindling water resources due to drought and other pressures, water utilities are seeking to tap into alternative water sources as a means to improve water sustainability. Reclaimed water consists of treated wastewater and is widely used for non-potable purposes, such as irrigation, both agricultural and recreational. However, the reclaimed

With dwindling water resources due to drought and other pressures, water utilities are seeking to tap into alternative water sources as a means to improve water sustainability. Reclaimed water consists of treated wastewater and is widely used for non-potable purposes, such as irrigation, both agricultural and recreational. However, the reclaimed water distribution system can be subject to substantial regrowth of microorganisms, including opportunistic pathogens, even following rigorous disinfection. Factors that can influence regrowth include temperature, organic carbon levels, disinfectant type, and the time transported (i.e., water age) in the system. One opportunistic pathogen (OP) that is critical to understanding microbial activity in both reclaimed and drinking water distribution systems is Acanthamoeba. In order to better understand the potential for this amoeba to proliferate in reclaimed water systems and influence other OPs, a simulated reclaimed water distribution system was studied. The objective of this study was to compare the prevalence of Acanthamoeba and one of its endosymbionts, Legionella, across varying assimilable organic carbon (AOC) levels, temperatures, disinfectants, and water ages in a simulated reclaimed water distribution system. The results of the study showed that cooler temperatures, larger water age, and chlorine conditions yielded the lowest detection of Acanthamoeba gene copies per mL or cm2 for bulk water and biofilm samples, respectively.
ContributorsDonaldson, Kandace (Author) / Ankeny, Casey (Thesis director) / Edwards, Marc (Committee member) / Pruden, Amy (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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Description
The effect of conflicting sensorimotor memories on optimal force strategies was explored. Subjects operated a virtual object controlled by a physical handle to complete a simple straight-line task. Perturbations applied to the handle induced a period of increased error in subject accuracy. After two blocks of 33 trials, perturbations switched

The effect of conflicting sensorimotor memories on optimal force strategies was explored. Subjects operated a virtual object controlled by a physical handle to complete a simple straight-line task. Perturbations applied to the handle induced a period of increased error in subject accuracy. After two blocks of 33 trials, perturbations switched direction, inducing increased error from the previous trials. Subjects returned after a 24-hour period to complete a similar protocol, but beginning with the second context and ending with the first. Interference from the first context on each day caused an increase in initial error for the second (P < 0.05). Following the rest period, subjects showed retention of the sensorimotor memory from the previous day through significantly decreased initial error (P = 3x10-6). However, subjects showed an increase in forces for each new context resulting from a sub-optimal motor strategy. Higher levels of total effort (P < 0.05) and a lack of separation between force values for opposing and non-opposing digits (P > 0.05) indicated a strategy that used more energy to complete the task, even when rates of learning appeared identical or improved. Two possible mechanisms for this lack of energy conservation have been proposed.
ContributorsSmith, Michael David (Author) / Santello, Marco (Thesis director) / Kleim, Jeffrey (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Oscillatory perturbations with varying amplitudes and frequencies have been found to significantly affect human standing balance. However, previous studies have only applied perturbation in either the anterior-posterior (AP) or the medio-lateral (ML) directions. Little is currently known about the impacts of 2D oscillatory perturbations on postural stability, which are

Oscillatory perturbations with varying amplitudes and frequencies have been found to significantly affect human standing balance. However, previous studies have only applied perturbation in either the anterior-posterior (AP) or the medio-lateral (ML) directions. Little is currently known about the impacts of 2D oscillatory perturbations on postural stability, which are more commonly seen in daily life (i.e., while traveling on trains, ships, etc.). This study investigated the effects of applying 2D perturbations vs 1D perturbations on standing stability, and how increasing the frequency and amplitude of perturbation impacts postural stability. A dual-axis robotic platform was utilized to simulate various oscillatory perturbations and evaluate standing postural stability. Fifteen young healthy subjects were recruited to perform quiet stance on the platform. Impacts of perturbation direction (i.e., 1D versus 2D), amplitude, and frequency on postural stability were investigated by analyzing different stability measures, specifically AP/ML/2D Center-of-Pressure (COP) path length, AP/ML/2D Time-to-Boundary (TtB), and sway area. Standing postural stability was compromised more by 2D perturbations than 1D perturbations, evidenced by a significant increase in COP path length and sway area and decrease in TtB. Further, the stability decreased as 2D perturbation amplitude and frequency increased. A significant increase in COP path length and decrease in TtB were consistently observed as the 2D perturbation amplitude and frequency increased. However, sway area showed a considerable increase only with increasing perturbation amplitude but not with increasing frequency.

ContributorsBerrett, Lauren Ann (Author) / Lee, Hyunglae (Thesis director) / Peterson, Daniel (Committee member) / Mechanical and Aerospace Engineering Program (Contributor) / School of International Letters and Cultures (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Description
Medial compartment knee osteoarthritis (OA) is a disease whose severity has been associated with the peak adduction moment during walking (pKAM). Unfortunately, measuring patients' pKAM to track their therapy progress involves the use of a gait laboratory which is expensive and time intensive. This study aimed to develop and assess

Medial compartment knee osteoarthritis (OA) is a disease whose severity has been associated with the peak adduction moment during walking (pKAM). Unfortunately, measuring patients' pKAM to track their therapy progress involves the use of a gait laboratory which is expensive and time intensive. This study aimed to develop and assess a regression method to predict the pKAM using only plantar pressure measurements. This approach could greatly reduce the burden of evaluating pKAM.
ContributorsThomas, Kevin Andrew (Author) / Hinrichs, Richard (Thesis director) / Harper, Erin (Committee member) / Favre, Julien (Committee member) / Barrett, The Honors College (Contributor) / Harrington Bioengineering Program (Contributor)
Created2014-05
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Description
Human walking is a complex and rhythmical activity that comprises of the brain, nerves and muscles. Neuromuscular disorder (NMD) is a broad term that refers to conditions that affect the proper use of muscles and nervous system, thus also impairing the walking or gait cycle of an individual. The improper

Human walking is a complex and rhythmical activity that comprises of the brain, nerves and muscles. Neuromuscular disorder (NMD) is a broad term that refers to conditions that affect the proper use of muscles and nervous system, thus also impairing the walking or gait cycle of an individual. The improper gait cycle might be attributed to the lack of force produced at the toe-off stage. This project addresses if it is possible to create an OpenSim model to find the ideal time and force magnitude needed of an assistive force ankle device to improve gait patterns in individuals with NMD.
ContributorsRivera, Jose Luis (Author) / Zhang, Wenlong (Thesis director) / Lockhart, Thurmon (Committee member) / Harrington Bioengineering Program (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2019-05