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Child chronic pain is both common and consequential and identification of malleable risk factors is a critical step towards developing effective interventions. Existing evidence points to the possibility that parent behavior may play a significant role in the development of children’s chronic pain through modeling of pain-related behaviors. An important

Child chronic pain is both common and consequential and identification of malleable risk factors is a critical step towards developing effective interventions. Existing evidence points to the possibility that parent behavior may play a significant role in the development of children’s chronic pain through modeling of pain-related behaviors. An important parental trait that predicts parent behavior in pain contexts is parental pain catastrophizing, which has been linked to child pain outcomes as well as to increased facial pain behavior in both parents and their children during pain induction. Existing research has examined facial pain behavior in aggregate, summarizing facial expressions over the course of an entire dyadic interaction, which does not allow for evaluation of the dynamic interplay between a parent and child. The current study aimed to test the hypothesis that higher parental catastrophizing would predict decreased flexibility in emotional dynamics between parent and child (reflected in facial affect during a parent-child interaction that occurs within the context of child pain-induction), which would in turn predict fewer child chronic pain symptoms. The approach used dynamic systems analysis of facial behaviors during the parent-child interaction during the child’s performance of a pain inducing cold pressor task to assess dyadic emotional flexibility. Nine-year old children from a larger sample of twins (N = 30) were video recorded during a cold-water pain task while their parents observed them. Videos of the children and their parent from these interactions were analyzed using facial action unit software (AffDex), into positive, neutral, and negative facial emotional expressions. Synchronized parent and child coded facial data were then analyzed for flexibility using GridWare (version 1.1). Parents completed the Pain Catastrophizing Scale (PCS) to assess parental trait pain catastrophizing and the Body Pain Location/Frequency scale to assess child chronic pain symptoms during the prior three months. Contrary to prediction, parental catastrophizing was related to higher levels of flexibility, and flexibility was unrelated to child chronic pain. Exploratory analyses indicated that children with higher levels of effortful control had more emotionally flexible interactions with their parent during the cold pressor, and emotionally flexible interactions predicting lower levels of children’s negative emotional responses to the acute pain task. suggesting some promising avenues for future research.
ContributorsSowards, Hayley Anne (Author) / Davis, Mary (Thesis director) / Lemery-Chalfant, Kathryn (Committee member) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Description
The purpose of this paper is to investigate the role of socialization in observed gender differences in emotional regulation. Drawing on a wide range of research regarding emotion, emotional regulation, and socialization, it is evident that the way in which boys and girls are taught to handle their emotions is

The purpose of this paper is to investigate the role of socialization in observed gender differences in emotional regulation. Drawing on a wide range of research regarding emotion, emotional regulation, and socialization, it is evident that the way in which boys and girls are taught to handle their emotions is not the same. Parents typically utilize an emotion-coaching philosophy with their daughters, and an emotion-dismissing philosophy with their sons, which may have detrimental consequences for the emotional regulation of boys and men. It is likely that gender differences in the socialization of emotional regulation stem from deeply rooted gender-emotion stereotypes within Western cultures. These gender-emotion stereotypes yield negative consequences in both the lives of men and women and are still to this day being reinforced by emotion socialization. This paper has implications for parents, teachers, therapists, and other individuals or professionals dealing with students, children, men, or women struggling with or learning about emotion.
ContributorsGriffin, Montana (Author) / Swanson, Jodi (Thesis director) / Scott Lynch, Jacquelyn (Committee member) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Description
Postpartum depression is recognized as the most common psychiatric disorder that appears in approximately 10-15% of women, with higher frequencies among low-income minority women. Past studies have revealed that depressive symptoms negatively impact child development and mother-child synchrony. The current study's purpose was to explore the effects of postpartum depressive

Postpartum depression is recognized as the most common psychiatric disorder that appears in approximately 10-15% of women, with higher frequencies among low-income minority women. Past studies have revealed that depressive symptoms negatively impact child development and mother-child synchrony. The current study's purpose was to explore the effects of postpartum depressive symptoms on later dyadic dysregulation. The data was collected from Las Madres Nuevas' study, a longitudinal investigation. Participants were 322 Mexican and Mexican American mother-infant dyads from the Phoenix metropolitan area who were recruited though a Maricopa Integrated Health System (MIHS) prenatal clinic. The Edinburgh Postnatal Depression Scale (EPDS) was used to measure depression 6 weeks postpartum. Additionally, the dysregulation-coding scheme used at child's 24 months of age measured the children's, mothers', and dyads' regulatory skills throughout their interactions with each other. Linear regression analyses were the central analyses of this study. In the first regression analysis, results showed that mother's age at prenatal visit (p= 0.44), 6-week depression score (p= 0.37), mother's education (p= 0.77), and number of biological children (p= 0.28) did not significantly predict dyadic dysregulation at 24 months. The second linear regression analysis concluded that the 6-week depression score, mother's country of birth, the interaction of maternal depression and country of birth, mother's education, mother's age at prenatal visit, and number of biological children also did not predict dyadic dysregulation at 24 months. Although not statistically significant, the findings suggest that the Hispanic Paradox theory, conservation of native cultural values, and strong social support have protective effects in Mexican immigrant and Mexican American childbearing women.
ContributorsOlivas Varela, Itzel (Author) / Luecken, Linda (Thesis director) / Lemery-Chalfant, Kathryn (Committee member) / Winstone, Laura (Committee member) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Description
Influenza is a deadly disease for which effective vaccines are sorely lacking. This is largely due to the phenomena of antigenic shift and drift in the influenza virus's surface proteins, hemagglutinin (HA) and neuraminidase (NA). The ectodomain of the matrix 2 protein (M2e) of influenza A, however, has demonstrated high

Influenza is a deadly disease for which effective vaccines are sorely lacking. This is largely due to the phenomena of antigenic shift and drift in the influenza virus's surface proteins, hemagglutinin (HA) and neuraminidase (NA). The ectodomain of the matrix 2 protein (M2e) of influenza A, however, has demonstrated high levels of conservation. On its own it is poorly immunogenic and offers little protection against influenza infections, but by combining it with a potent adjuvant, this limitation may be overcome. Recombinant immune complexes, or antigens fused to antibodies that have been engineered to form incredibly immunogenic complexes with one another, were previously shown to be useful, immunogenic platforms for the presentation of various antigens and could provide the boost in immunogenicity that M2e needs to become a powerful universal influenza A vaccine. In this thesis, genetic constructs containing geminiviral replication proteins and coding for a consensus sequence of dimeric M2e fused to antibodies featuring complimentary epitopes and epitope tags were generated and used to transform Agrobacterium tumefaciens. The transformed bacteria was then used to cause Nicotiana benthamiana to transiently express M2e-RICs at very high levels, with enough RICs being gathered to evaluate their potency in future mouse trials. Future directions and areas for further research are discussed.
ContributorsFavre, Brandon Chetan (Author) / Mason, Hugh (Thesis director) / Mor, Tsafrir (Committee member) / Diamos, Andrew (Committee member) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Description
Vaccine opposition is a growing problem in developed countries where dropping vaccination rates threaten general public health by laying the foundation for resurgence and reemergence of previously eradicated infectious diseases. This thesis argues that the current movement is only the most recent incarnation of opposition that has co-evolved with vaccine

Vaccine opposition is a growing problem in developed countries where dropping vaccination rates threaten general public health by laying the foundation for resurgence and reemergence of previously eradicated infectious diseases. This thesis argues that the current movement is only the most recent incarnation of opposition that has co-evolved with vaccine practices for the duration of their mutual histories. Part one provides a historical context for the current movement using the example of the development and deployment of the smallpox vaccine as a representative timeline of vaccine acceptance and opposition. Part two describes the current movement in the United States and the United Kingdom, interprets the reasons for the conclusions drawn by vaccine-concerned parents, and provides a framework for public health officials to approach the issues.
ContributorsKost, Stephanie Michelle (Author) / Lynch, John (Thesis director) / Hurlbut, Ben (Committee member) / Robert, Jason (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor) / School of Life Sciences (Contributor)
Created2013-12
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Description
Dengue virus infects millions of people every year. Yet there is still no vaccine available to prevent it. Here we use a neutralizing epitope determinant on the dengue envelope (E) protein as an immunogen to be vectored by a measles virus (MV) vaccine. However the domain III (DIII) of the

Dengue virus infects millions of people every year. Yet there is still no vaccine available to prevent it. Here we use a neutralizing epitope determinant on the dengue envelope (E) protein as an immunogen to be vectored by a measles virus (MV) vaccine. However the domain III (DIII) of the dengue 2 E protein is too small to be immunogenic by itself. In order for it to be displayed on a larger particle, it was inserted into the amino terminus of small hepatitis B surface antigen (HBsAg, S) coding sequence. To generate the recombinant MV vector and verify the efficiency of this concept, a reverse genetics system was used where the MV vectors express one or two additional transcription units to direct the assembly of hybrid HBsAg particles. Two types of recombinant measles virus were produced: pB(+)MVvac2(DIII-S,S)P and pB(+)MVvac2(DIII-S)N. Virus recovered from pB(+)MVvac2(DIII-S,S)P was viable. An ELISA assay was performed to demonstrate the expression and secretion of HBsAg. Supernatant from MVvac2(DIII-S,S)P infected cells confirmed that hybrid HBsAg-domain III particles with a density similar to traditional HBsAg particles were released. Characteristics of the subviral particle have been analyzed for the successful incorporation of domain III. The replication fitness of the recombinant MV was evaluated using multi-step growth kinetics and showed reduced replication fitness when compared to the parental strain MVvac2. This demonstrates that viral replication is hindered by the addition of the two inserts into MV genome. Further analysis of MVvac2(DIII-S)N is needed to justify immune response studies in a small animal model using both of the generated recombinant vectors.
ContributorsHarahap, Indira Saridewi (Author) / Reyes del Valle, Jorge (Thesis director) / Hogue, Brenda (Committee member) / Misra, Rajeev (Committee member) / Barrett, The Honors College (Contributor) / T. Denny Sanford School of Social and Family Dynamics (Contributor) / School of Human Evolution and Social Change (Contributor) / School of Life Sciences (Contributor)
Created2014-05
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Description
Climate change presents a significant threat to human health, both mental and physical; as a result, it has become one of the most commonly discussed phenomena of the 21st century. As many people are aware, a wide range of social and physical factors affects mental health. However, many people fail

Climate change presents a significant threat to human health, both mental and physical; as a result, it has become one of the most commonly discussed phenomena of the 21st century. As many people are aware, a wide range of social and physical factors affects mental health. However, many people fail to realize that these increases global temperatures also have a significant impact on mental health as a result of increased vulnerability that is often manifested through one's emotions. By analyzing perceptions of people across the globe, in the United Kingdom, New Zealand, and Fiji, we were able to pinpoint these emotions and trace them individual's feelings of worry, distress, and hope that resulted from their perceived impacts on climate change. Overall, we found that people tend to have overall more negative emotional reaction when it comes to the perceived effects of climate change. Of the respondents, more men than women expressed concern regarding the various negative implications. Finally, those in the United Kingdom exhibited a stronger emotional response, followed by those in New Zealand and Fiji, respectively.
ContributorsSmith, Austin Lee (Author) / Wutich, Amber (Thesis director) / du Bray, Margaret (Committee member) / Department of Psychology (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / School of Life Sciences (Contributor) / School of Human Evolution and Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
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Description
Self-regulation in the form of coping with emotions is something that most people have effectively adapted to by adulthood. This is an organically learned process that begins in early childhood through play, parenting, education, and peer interactions. This study examines whether six children aged 4-5 (M age= 4.72, SD= 0.372,

Self-regulation in the form of coping with emotions is something that most people have effectively adapted to by adulthood. This is an organically learned process that begins in early childhood through play, parenting, education, and peer interactions. This study examines whether six children aged 4-5 (M age= 4.72, SD= 0.372, 50% female, 100% Caucasian) are able to understand basic emotions and how to cope with them through one of two protocols. The conditions were either directive instruction or embodied cognition, and children were evaluated with a pre and post-test measure. Findings did not indicate any significant effect of the conditions on memorizing coping mechanisms, nor did it indicate that there was a significant improvement in emotion understanding following the sessions. These findings were limited by the sample size and participant interest.
ContributorsLittell, Naila Sabre (Co-author) / Frutiger, Kiana (Co-author) / Fey, Richard (Thesis director) / Kupfer, Anne (Committee member) / School of Life Sciences (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12
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Description
Emotions have been defined as coordinated and functional changes in subjective experience, motivation, physiological activation, instrumental behavior, expressive behavior, and cognition that are evoked by important threats or opportunities in the environment. The proposed study looks at cognitive changes associated with the experience of several positive emotions, with a specific

Emotions have been defined as coordinated and functional changes in subjective experience, motivation, physiological activation, instrumental behavior, expressive behavior, and cognition that are evoked by important threats or opportunities in the environment. The proposed study looks at cognitive changes associated with the experience of several positive emotions, with a specific focus on awe. Prior research shows that positive emotions tend to increase people's use of cognitive heuristics (i.e. mental shortcuts used to simplify information we intake from the environment) and changes how they apply rules of thumb from stored knowledge to make decisions. Stereotypes, or assumptions about the characteristics held by individual members of a group, are one such heuristic. Awe, in contrast to other positive emotions, has been found to reduce people's tendency to rely on heuristics, rather than increasing its use. Thus, awe should tend to reduce stereotyping specifically. Participants made judgments on three characteristics and two types of theoretically valuable true/false statements. However, for both our measures, awe had no significant effect on stereotyping. Participants in the enthusiasm condition were significantly more likely than those in the awe condition to correctly identify stereotype-inconsistent statements present in the biography, which is the opposite of the predicted direction. Patterns for all four emotion conditions trended similarly to our predictions for stereotype-consistent statements correctly marked as being absent in the biography. There were no significant differences in ratings of three traits. Implications for enthusiasm and awe are discussed in the context of stereotypes of social objects and schemas of nonsocial objects.
ContributorsMurwin, Paige Elizabeth (Co-author) / O'Neil, Makenzie (Co-author) / Shiota, Michelle (Thesis director) / Davis, Mary (Committee member) / Sanford School of Social and Family Dynamics (Contributor) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12
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Description
Working memory is the cognitive system responsible for storing and maintaining information in short-term memory and retrieving cues from long-term memory. Working memory capacity (WMC) is needed for goal maintenance and to ignore task-irrelevant stimuli (Engle & Kane, 2003). Emotions are one type of task-irrelevant stimuli that could distract an

Working memory is the cognitive system responsible for storing and maintaining information in short-term memory and retrieving cues from long-term memory. Working memory capacity (WMC) is needed for goal maintenance and to ignore task-irrelevant stimuli (Engle & Kane, 2003). Emotions are one type of task-irrelevant stimuli that could distract an individual from a task (Smallwood, Fitzgerald, Miles, & Phillips, 2009). There are studies that show there is a relation between emotions and working memory capacity. The direction of this relationship, though, is unclear (Kensinger, 2009). In this study, emotions served as a distractor and task performance was examined for differences in the effect of emotion depending on participants' working memory capacity. The participants watched a mood induction video, then were told to complete a complex-span working memory task. The mood induction was successful- participants watching the negative emotional video were in a less positive mood after watching the video than the participants that watched a neutral video. However, the results of the complex-span working memory task showed no significant difference in the results between participants in the negative versus neutral mood. These results may provide support to an alternative hypothesis: cognitive tasks can diminish the effects of emotions (Dillen, Heslenfeld, & Koole, 2009).
ContributorsAhmed, Sania (Author) / Brewer, Gene (Thesis director) / Wingert, Kimberly (Committee member) / Blais, Chris (Committee member) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12