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Description
Flow measurement has always been one of the most critical processes in many industrial and clinical applications. The dynamic behavior of flow helps to define the state of a process. An industrial example would be that in an aircraft, where the rate of airflow passing the aircraft is used to

Flow measurement has always been one of the most critical processes in many industrial and clinical applications. The dynamic behavior of flow helps to define the state of a process. An industrial example would be that in an aircraft, where the rate of airflow passing the aircraft is used to determine the speed of the plane. A clinical example would be that the flow of a patient's breath which could help determine the state of the patient's lungs. This project is focused on the flow-meter that are used for airflow measurement in human lungs. In order to do these measurements, resistive-type flow-meters are commonly used in respiratory measurement systems. This method consists of passing the respiratory flow through a fluid resistive component, while measuring the resulting pressure drop, which is linearly related to volumetric flow rate. These types of flow-meters typically have a low frequency response but are adequate for most applications, including spirometry and respiration monitoring. In the case of lung parameter estimation methods, such as the Quick Obstruction Method, it becomes important to have a higher frequency response in the flow-meter so that the high frequency components in the flow are measurable. The following three types of flow-meters were: a. Capillary type b. Screen Pneumotach type c. Square Edge orifice type To measure the frequency response, a sinusoidal flow is generated with a small speaker and passed through the flow-meter that is connected to a large, rigid container. True flow is proportional to the derivative of the pressure inside the container. True flow is then compared with the measured flow, which is proportional to the pressure drop across the flow-meter. In order to do the characterization, two LabVIEW data acquisition programs have been developed, one for transducer calibration, and another one that records flow and pressure data for frequency response testing of the flow-meter. In addition, a model that explains the behavior exhibited by the flow-meter has been proposed and simulated. This model contains a fluid resistor and inductor in series. The final step in this project was to approximate the frequency response data to the developed model expressed as a transfer function.
ContributorsHu, Jianchen (Author) / Macia, Narciso (Thesis advisor) / Pollat, Scott (Committee member) / Rogers, Bradley (Committee member) / Arizona State University (Publisher)
Created2013
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Description
The world of healthcare can be seen as dynamic, often an area where technology and science meet to consummate a greater good for humanity. This relationship has been working well for the last century as evident by the average life expectancy change. For the greater of the last five decades

The world of healthcare can be seen as dynamic, often an area where technology and science meet to consummate a greater good for humanity. This relationship has been working well for the last century as evident by the average life expectancy change. For the greater of the last five decades the average life expectancy at birth increased globally by almost 20 years. In the United States specifically, life expectancy has grown from 50 years in 1900 to 78 years in 2009. That is a 76% increase in just over a century. As great as this increase sounds for humanity it means there are soon to be real issues in the healthcare world. A larger older population will need more healthcare services but have fewer young professionals to provide those services. Technology and science will need to continue to push the boundaries in order to develop and provide the solutions needed to continue providing the aging world population sufficient healthcare. One solution sure to help provide a brighter future for healthcare is mobile health (m-health). M-health can help provide a means for healthcare professionals to treat more patients with less work expenditure and do so with more personalized healthcare advice which will lead to better treatments. This paper discusses one area of m-health devices specifically; human breath analysis devices. The current laboratory methods of breath analysis and why these methods are not adequate for common healthcare practices will be discussed in more detail. Then more specifically, mobile breath analysis devices are discussed. The topic will encompass the challenges that need to be met in developing such devices, possible solutions to these challenges, two real examples of mobile breath analysis devices and finally possible future directions for m-health technologies.
ContributorsLester, Bryan (Author) / Forzani, Erica (Thesis advisor) / Xian, Xiaojun (Committee member) / Trimble, Steve (Committee member) / Arizona State University (Publisher)
Created2012
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Description
For the increasing concerns of influence on environment by fossil-electricity generation, application of renewable energy becomes one of the most focused issues in society. Based on the limitation on urban environment, wind turbines, which can be mounted on rooftop or between buildings, are regarded as a feasible way for wind

For the increasing concerns of influence on environment by fossil-electricity generation, application of renewable energy becomes one of the most focused issues in society. Based on the limitation on urban environment, wind turbines, which can be mounted on rooftop or between buildings, are regarded as a feasible way for wind energy generation. This study presents wind flow simulations in a large-scale environment with certain dimension buildings. Different inlet velocity boundary conditions are tested firstly, and the non-uniform inlet boundary condition shows better agreement with realistic situation. Turbulence intensity is set to be 10% for comparison consistency. The k-epsilon turbulence model is regarded as a better simulation for this certain condition. After that, three different structures, which include single building, pristine double building and modified circular gap double building systems, are tested in this environment condition. The result shows 18.8% velocity increasing on the top of single building system. Pristine double building systems are tested with 4 different gap distances, and building with 10 meters gap achieved the best velocity condition, which 32.8% velocity increasing and 11.8% improvement comparing to single building system, respectively. But the location of maximum velocity moves to the gap and the maximum velocity on the rooftop of double building system is approximately 5.1% lower than single building system. Based on previous study, modified circular gap double building system is created with 10 meters gap. Comparing result with single building system, modified circular gap system achieves higher improvement for wind flow, whose improvement of velocity increasing in the gap and on the rooftop of building are 47.1% and 3.0%, respectively. As a result, the modified circular gap double building can be regarded as a high efficiency system of environmental wind flow over buildings for renewable energy system.
ContributorsLi, Guoyi (Author) / Huang, Huei-Ping (Thesis advisor) / Lee, Taewoo (Committee member) / Forzani, Erica (Committee member) / Arizona State University (Publisher)
Created2015
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Description
This study uses Computational Fluid Dynamics (CFD) modeling to analyze the

dependence of wind power potential and turbulence intensity on aerodynamic design of a

special type of building with a nuzzle-like gap at its rooftop. Numerical simulations using

ANSYS Fluent are carried out to quantify the above-mentioned dependency due to three

major geometric parameters

This study uses Computational Fluid Dynamics (CFD) modeling to analyze the

dependence of wind power potential and turbulence intensity on aerodynamic design of a

special type of building with a nuzzle-like gap at its rooftop. Numerical simulations using

ANSYS Fluent are carried out to quantify the above-mentioned dependency due to three

major geometric parameters of the building: (i) the height of the building, (ii) the depth of

the roof-top gap, and (iii) the width of the roof-top gap. The height of the building is varied

from 8 m to 24 m. Likewise, the gap depth is varied from 3 m to 5 m and the gap width

from 2 m to 4 m. The aim of this entire research is to relate these geometric parameters of

the building to the maximum value and the spatial pattern of wind power potential across

the roof-top gap. These outcomes help guide the design of the roof-top geometry for wind

power applications and determine the ideal position for mounting a micro wind turbine.

From these outcomes, it is suggested that the wind power potential is greatly affected by

the increasing gap width or gap depth. It, however, remains insensitive to the increasing

building height, unlike turbulence intensity which increases with increasing building

height. After performing a set of simulations with varying building geometry to quantify

the wind power potential before the installation of a turbine, another set of simulations is

conducted by installing a static turbine within the roof-top gap. The results from the latter

are used to further adjust the estimate of wind power potential. Recommendations are made

for future applications based on the findings from the numerical simulations.
ContributorsKailkhura, Gargi (Author) / Huang, Huei-Ping (Thesis advisor) / Rajagopalan, Jagannathan (Committee member) / Forzani, Erica (Committee member) / Arizona State University (Publisher)
Created2017
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Description
Spirometry is a type of pulmonary function test that measures the amount of air volume and the speed of air flow from a patient's breath in order to assess lung function. The goal of this project is to develop and validate a mobile spirometer technology based on a differential pressure

Spirometry is a type of pulmonary function test that measures the amount of air volume and the speed of air flow from a patient's breath in order to assess lung function. The goal of this project is to develop and validate a mobile spirometer technology based on a differential pressure sensor. The findings in this paper are used in a larger project that combines the features of a capnography device and a spirometer into a single mobile health unit known as the capno-spirometer. The following paper discusses the methods, experiments, and prototypes that were developed and tested in order to create a robust and accurate technology for all of the spirometry functions within the capno-spirometer. The differential pressure sensor is set up with one inlet measuring the pressure inside the spirometer tubing and the other inlet measuring the ambient pressure of the environment. The inlet measuring the inside of the tubing is very sensitive to its orientation and position with respect to the path of the air flow. It is found that taking a measurement from the center of the flow is 50% better than from the side wall. The sensor inlet is optimized at 37 mm from the mouthpiece inlet. The unit is calibrated by relating the maximum pressure sensor voltage signal to the peak expiratory flow rate (PEF) taken during a series of spirometry tests. In conclusion, this relationship is best represented as a quadratic function and a calibration equation is computed to provide a flow rate given a voltage change. The flow rates are used to calculate the four main spirometry parameters: PEF, FVC, FEV1, and FER. These methods are then referenced with the results from a commercial spirometer for validation. After validation, the pressure-based spirometry technology is proven to be both robust and accurate.
ContributorsMiller, Dylan (Author) / Forzani, Erica (Thesis advisor) / Trimble, Steve (Committee member) / Xian, Xiaojun (Committee member) / Arizona State University (Publisher)
Created2013
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Description
The project is mainly aimed at detecting the gas flow rate in Biosensors and medical health applications by means of an acoustic method using whistle based device. Considering the challenges involved in maintaining particular flow rate and back pressure for detecting certain analytes in breath analysis the proposed system along

The project is mainly aimed at detecting the gas flow rate in Biosensors and medical health applications by means of an acoustic method using whistle based device. Considering the challenges involved in maintaining particular flow rate and back pressure for detecting certain analytes in breath analysis the proposed system along with a cell phone provides a suitable way to maintain the flow rate without any additional battery driven device. To achieve this, a system-level approach is implemented which involves development of a closed end whistle which is placed inside a tightly fitted constant back pressure tube. By means of experimentation pressure vs. flowrate curve is initially obtained and used for the development of the particular whistle. Finally, by means of an FFT code in a cell phone the flow rate vs. frequency characteristic curve is obtained. When a person respires through the device a whistle sound is generated which is captured by the cellphone microphone and a FFT analysis is performed to determine the frequency and hence the flow rate from the characteristic curve. This approach can be used to detect flow rate as low as low as 1L/min. The concept has been applied for the first time in this work to the development and optimization of a breath analyzer.
ContributorsRavichandran, Balaje Dhanram (Author) / Forzani, Erica (Thesis advisor) / Xian, Xiaojun (Committee member) / Huang, Huei-Ping (Committee member) / Arizona State University (Publisher)
Created2012