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- Creators: Barrett, The Honors College
Description
The purpose of this study was to examine swallowing patterns using ultrasound technology subsequent to the implementation of two therapeutic interventions. Baseline swallow patterns were compared to swallows after implementation of therapeutic interventions common in both feeding therapy (FT) and orofacial myofunctional therapy (OMT). The interventions consist of stimulation of the tongue by z-vibe and tongue pops. Changes in swallowing patterns are described, and similarities of interventions across the two professions are discussed. Ultrasound research in the realm of swallowing is sparse despite having potential clinical application in both professions. In using ultrasound, this study outlines a protocol for utilization of a hand-held probe and reinforces a particular protocol described in the literature. Real-time ultrasound recordings of swallows for 19 adult female subjects were made. Participants with orofacial myofunctional disorder are compared to a group with typical swallowing and differences in swallowing patterns are described. Three stages of the oral phase of the swallow were assigned based on ultrasonic observation of the tongue shape. Analysis involves total duration of the swallow, duration of the three stages in relation to the total duration of the swallow, and the number of swallows required for the bolus to be cleared from the oral cavity. No significant effects of either intervention were found. Swallowing patterns showed a general trend to become faster in total duration subsequent to each intervention. An unexpected finding showed significant changes in the relationship between the bolus preparation stage and the bolus transportation stage when comparing the group classified as having a single swallow and the group classified as having multiple swallows.
ContributorsMckay, Michelle Diane (Author) / Weinhold, Juliet (Thesis director) / Scherer, Nancy (Committee member) / Department of Speech and Hearing Science (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
This project creates a possible framework for the application of music therapy to reduce test anxiety in students. Although music therapy has grown in recent years as a treatment method for a variety of mental health and wellness problems, it has yet to be comprehensively applied to the specific issue of test anxiety. Some studies have examined the use of music in testing situations in order to reduce anxiety or improve academic performance. However, more in-depth music therapy interventions are a promising, largely untried treatment possibility for students suffering from this type of anxiety.
ContributorsCowan, Sarah Elizabeth (Author) / Crowe, Barbara (Thesis director) / Rio, Robin (Committee member) / Barrett, The Honors College (Contributor) / School of Music (Contributor) / School of International Letters and Cultures (Contributor)
Created2014-12
Description
The fashion industry dubs couture as high fashion, yet couture never reaches the finish line when it comes to comfort. Most of the brand name high heels on the market are too painful to wear for long periods of time. For this project, I have developed 3D printed high heels with detachable insoles that will relieve tired feet based on the principle of reflexology. The product integrates traditional flexible insoles with Arduino computing and the result is a functional surface that can ease the pain of the wearer. This paper introduces the product and with it, under-explored opportunities to customize your own high heels at home. Essentially, each consumer will have the ability to personalize and switch out their style without sacrificing comfort. Soon, a consumer will be a designer.
ContributorsNguyen, Nhi N. (Author) / Ingalls, Todd (Thesis director) / Gigantino, Josh (Committee member) / Barrett, The Honors College (Contributor) / Herberger Institute for Design and the Arts (Contributor) / School of Arts, Media and Engineering (Contributor)
Created2015-05
Description
Robotic rehabilitation for upper limb post-stroke recovery is a developing technology. However, there are major issues in the implementation of this type of rehabilitation, issues which decrease efficacy. Two of the major solutions currently being explored to the upper limb post-stroke rehabilitation problem are the use of socially assistive rehabilitative robots, robots which directly interact with patients, and the use of exoskeleton-based systems of rehabilitation. While there is great promise in both of these techniques, they currently lack sufficient efficacy to objectively justify their costs. The overall efficacy to both of these techniques is about the same as conventional therapy, yet each has higher overhead costs that conventional therapy does. However there are associated long-term cost savings in each case, meaning that the actual current viability of either of these techniques is somewhat nebulous. In both cases, the problems which decrease technique viability are largely related to joint action, the interaction between robot and human in completing specific tasks, and issues in robot adaptability that make joint action difficult. As such, the largest part of current research into rehabilitative robotics aims to make robots behave in more "human-like" manners or to bypass the joint action problem entirely.
ContributorsRamakrishna, Vijay Kambhampati (Author) / Helms Tillery, Stephen (Thesis director) / Buneo, Christopher (Committee member) / Barrett, The Honors College (Contributor) / Economics Program in CLAS (Contributor) / W. P. Carey School of Business (Contributor) / School of Life Sciences (Contributor)
Created2015-05
Description
There are many parallels between human and equine sports medicine, including the roots of athletics, the development of specialized medicine, and injuries to the athletes. The most remarkable similarities are seen in tendinopathies. Because of the similarities between human and equine tendons, equine athletes serve as one of the best animal models to study tendon physiology and tendon injuries for application to human medicine. Because of this, many therapies have already successfully crossed from one realm of sports medicine to the other, the most notable of which are stem cell therapy, Interleukin-1 Receptor Antagonist (IRAP), and platelet rich plasma (PRP) therapies. There are also several therapies on the horizon that are very promising to potentially be successful in both human and equine athletes. However, some of these novel therapies are raising ethical questions. There are many regulations in place to protect against or address potential ethical conflicts in human medicine. The same trend is not seen in equine medicine. While there are rules enforced by many equestrian federations regarding ethical concerns and veterinary medicine, the information is not nearly as complete as it should be. Because they lack the autonomy that typical human patient possesses, equine athletes require significantly more advocacy from their veterinarians than human athletes do from their physicians. Additionally, there is a lack of large animal model studies secondary to cost and overall value of equine athletes to their owners, riders, and trainers. Ultimately it becomes an issue of veterinary ethics whether to pursue a novel or conventional treatment for an equine athlete. With biotechnology advancing as quickly as it is, new studies must be done and new regulations must be written in order to keep all fields of sports medicine operating safely and ethically for all athletes involved, regardless of species.
ContributorsWaslewski, Samantha Paige (Author) / Lynch, John (Thesis director) / Foley, James (Committee member) / School of Life Sciences (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Human genetic engineering, the manipulation of genomic DNA, is an up and coming field in which soon we will no longer be asking if we can do it, but should we do it? It raises ethical questions regarding autonomy, the concept that an individual is capable of self-governance and making informed decisions, as well as consent of those who undergo genetic manipulation. Along with the ethical questions come issues of equality, equal opportunity of usage, and responsibility of those who use such technologies. The benefits and consequences of genetically engineering humans must be examined, such as the eradication of genetic diseases and the ability to alter ourselves as we desire, as well as the possible unintended outcomes, such as a two-class society and insurmountable inequality. Eugenics and the Transhumanism movement will also be examined, and how they could affect genetic engineering. Regulations will be needed, to limit parents on how they can modify their children and on how adults can modify themselves, to ensure the safe future of genetic engineering.
ContributorsThompson, Carlie Jane (Author) / McGregor, Joan (Thesis director) / Robert, Jason Scott (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2013-12
Description
This collaborative, creative project includes 100 music therapy interventions for all ages including children 0-18, young adults 19-25, adults 26-65, and older adults/geriatrics 65-death. Five goal areas are focused on for each of the four populations. These goal areas are cognitive, social, physical, emotional, and behavioral. Each intervention was modeled after Duerksen's (1978) five ways in which music can be used as a organizational, helpful, learning tool: (1) Music as a carrier of information (2) Music as a reinforcer (3) Music as a background for learning (4) Music as a physical structure for the learning activity (5) Music as a reflection of skills or processes learned. The creative possibilities of interacting musically with clients of all ages and levels of functioning are what led us to create this project. The wide variety of populations covered in this project include children on the autism spectrum, young adults suffering from depression, and geriatrics exhibiting symptoms of Dementia. This book encompasses all of these populations and more, providing client-centered activities to use in music therapy sessions. This project was created with the intention of sharing it with fellow students and peers, as well as for the future use of ourselves in our internship experiences and careers.
ContributorsHouck, Olivia Kathryn (Co-author) / Morrison, Sydney (Co-author) / Crowe, Barbara (Thesis director) / Rio, Robin (Committee member) / Barrett, The Honors College (Contributor) / School of Music (Contributor)
Created2014-05
Description
This thesis critically examines the scientific and ethical dimensions of the novel and controversial technology of mitochondrial replacement therapy (MRT). The first portion provides a background on mitochondrial diseases and examines how these organelles (mitochondria) have left humans vulnerable to disease. The second portion of the thesis examines the technology of mitochondrial replacement therapy and what research contributed to the development of MRT. Finally, the third section responds to the ethical and legal concerns proposed and outlined by the Nuffield Council of Bioethics. After careful consideration of all legal and ethical concerns, it is concluded that the technology of MRT should be pursued under careful foresight with the idea that the technology is already happening and we must move forward in a way that provides the greatest information.
ContributorsLee, Giselle Alexandra (Author) / Fette, Donald (Thesis director) / Hurlbut, Ben (Committee member) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
Description
This paper introduces MisophoniAPP, a new website for managing misophonia. It will briefly discuss the nature of this chronic syndrome, which is the experience of reacting strongly to certain everyday sounds, or “triggers”. Various forms of Cognitive Behavioral Therapy and the Neural Repatterning Technique are currently used to treat misophonia, but they are not guaranteed to work for every patient. Few apps exist to help patients with their therapy, so this paper describes the design and creation of a new website that combines exposure therapy,
relaxation, and gamification to help patients alleviate their misophonic reflexes.
relaxation, and gamification to help patients alleviate their misophonic reflexes.
ContributorsNoziglia, Rachel Elisabeth (Author) / McDaniel, Troy (Thesis director) / Anderson, Derrick (Committee member) / Computer Science and Engineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Glioblastoma (GBM) is an extremely malignant form of brain cancer characterized by rapid progression and poor patient survival. Even after standard of care treatments, less than ten percent of patients with this disease survive five years. More effective therapeutic options are urgently needed to improve outcomes for patients with GBM. Adequate drug delivery is a critical challenge in GBM treatment, as drugs delivered systemically must be able to penetrate the blood brain barrier (BBB) and reach the tumor at therapeutic levels. To address this, we developed a resource to catalog BBB penetration information for investigational agents currently in clinical trials in cancer. Using an in silico prediction model and manual annotation to capture existing knowledge from the published literature, BBB content for ~500 investigational drugs was added to the investigational database tool. In addition to BBB content, the database also includes information on the gene targets of the included therapies. The investigational database tool was used to identify investigational agents that (1) may have increased activity against GBM based on the presence of a specific mutation in the tumor sample and (2) have evidence suggesting the compounds may penetrate the BBB. By prioritizing investigational agents for further study based on evidence for BBB penetration, this resource can help the GBM research community pursue more effective treatments for GBM.
ContributorsHerring, Emily Lora (Author) / Coursen, Jerry (Thesis director) / Byron, Sara (Committee member) / Biomedical Informatics Program (Contributor) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05