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- All Subjects: Developmental Psychology
- All Subjects: Genetics
- Genre: Academic theses
- Creators: Lemery-Chalfant, Kathryn
- Member of: ASU Electronic Theses and Dissertations
- Resource Type: Text
Description
Using data from an eight-year longitudinal study of 214 children's social and emotional development, I conducted three studies to (1) examine patterns of agreement for internalizing (INT) and externalizing (EXT) symptomatology among different informants (mothers, fathers, teachers, and adolescents) using a recently developed structural equation modeling approach for multi-trait, multi-method data; (2) examine the developmental trajectories for INT and EXT and predict individual differences in symptom development using temperament and parenting variables; and (3) describe patterns of INT and EXT co-occurrence and predict these patterns from temperament and parenting. In Study 1, longitudinal invariance was established for mothers', fathers' and teachers' reports over a six-year period. Sex, age, and SES did not substantially moderate agreement among informants, although both sex and age were differentially related to symptomatology depending on the informant. Agreement among teachers and mothers, but not among mothers and fathers, differed by domain of symptomatology, and was greater for EXT than for INT. In Study 2, latent profile analysis, a person-centered analytic approach, did not provide easily interpretable patterns of symptom development, a failure that is likely the result of the relatively modest sample size. Latent growth curve models, an alternative analytic approach, did provide good fit to the data. Temperament and parenting variables were examined as predictors of the latent growth parameters in these models. Although there was little prediction of the slope, effortful control was negatively related to overall levels of EXT, whereas impulsivity and anger were positively related. Mutually responsive orientation, a measure of the parent-child relationship, was a more consistent predictor of EXT than was parental warmth. Furthermore, the relation between mutually responsive orientation and EXT was partially mediated by inhibitory control. Across informants, there were few consistent predictors of INT. In Study 3, latent profile analysis was used to classify individuals into different patterns of INT and EXT co-occurrence. In these models, a similar class structure was identified for mothers and for teachers. When temperament and parenting were examined as predictors of co-occurring symptomatology, few significant interactions were found and results largely replicated prior findings from this data set using arbitrary symptom groups.
ContributorsSulik, Michael John (Author) / Eisenberg, Nancy (Thesis advisor) / Spinrad, Tracy L (Thesis advisor) / Lemery-Chalfant, Kathryn (Committee member) / Wolchik, Sharlene A (Committee member) / Arizona State University (Publisher)
Created2013
Description
The current study delineated the developmental trajectories of early childhood externalizing and internalizing symptoms reported by mothers and fathers, and examined the role of the 18-month observed parenting quality × Respiratory Sinus Arrhythmia
(RSA) interaction in predicting these trajectories. Child sex was tested as a covariate and moderator. It was found that children's low baseline RSA or high RSA reactivity , in comparison to high baseline RSA or low RSA reactivity , was more reactive as a function
of early parenting quality when predicting the development of early childhood problem symptoms. Differential patterns of the interaction between parenting quality and RSA were detected for mothers' and fathers' reports. Mother-reported models showed a diathesis-stress pattern, whereas the father-reported model showed a vantage-sensitivity pattern, especially for internalizing symptoms. This may imply the potential benefit of fathers' active engagement in children's early development. In addition, the effect of the parenting quality × RSA interaction in predicting the mother-reported models was found
to be further moderated by child sex. Specifically, the parenting quality × baseline RSA interaction was significantly predictive of girls' 54-month internalizing, and the parenting quality × RSA reactivity interaction significantly predicted boys' internalizing slope. Girls with low baseline RSA or boys with high RSA reactivity were vulnerable to the less positive parenting, exhibiting high levels of 54-month internalizing symptoms or slow decline in internalizing over time, respectively. Future research directions were discussed in terms of integrating the measures of SNS and PNS in psychopathology study,
exploring the mechanisms underlying the sex difference in parenting quality × RSA interaction, and comparing the findings of children's typical and atypical development.
(RSA) interaction in predicting these trajectories. Child sex was tested as a covariate and moderator. It was found that children's low baseline RSA or high RSA reactivity , in comparison to high baseline RSA or low RSA reactivity , was more reactive as a function
of early parenting quality when predicting the development of early childhood problem symptoms. Differential patterns of the interaction between parenting quality and RSA were detected for mothers' and fathers' reports. Mother-reported models showed a diathesis-stress pattern, whereas the father-reported model showed a vantage-sensitivity pattern, especially for internalizing symptoms. This may imply the potential benefit of fathers' active engagement in children's early development. In addition, the effect of the parenting quality × RSA interaction in predicting the mother-reported models was found
to be further moderated by child sex. Specifically, the parenting quality × baseline RSA interaction was significantly predictive of girls' 54-month internalizing, and the parenting quality × RSA reactivity interaction significantly predicted boys' internalizing slope. Girls with low baseline RSA or boys with high RSA reactivity were vulnerable to the less positive parenting, exhibiting high levels of 54-month internalizing symptoms or slow decline in internalizing over time, respectively. Future research directions were discussed in terms of integrating the measures of SNS and PNS in psychopathology study,
exploring the mechanisms underlying the sex difference in parenting quality × RSA interaction, and comparing the findings of children's typical and atypical development.
ContributorsLi, Yi (Author) / Eisenberg, Nancy (Thesis advisor) / Spinrad, Tracy (Thesis advisor) / Lemery-Chalfant, Kathryn (Committee member) / Wilkens, Natalie (Committee member) / Arizona State University (Publisher)
Created2014
Description
Fibromyalgia (FM) is a chronic musculoskeletal disorder characterized by widespread pain, fatigue, and a variety of other comorbid physiological and psychological characteristics, including a deficit of positive affect. Recently, the focus of research on the pathophysiology of FM has considered the role of a number of genomic variants. In the current manuscript, case-control analyses did not support the hypothesis that FM patients would differ from other chronic pain groups in catechol-O-methyltransferase (COMT) and mu-opioid receptor (OPRM1) genotype. However, evidence is provided in support of the hypothesis that functional single nucleotide polymorphisms on the COMT and OPRM1 genes would be associated with risk and resilience, respectively, in a dual processing model of pain-related positive affective regulation in FM. Forty-six female patients with a physician-confirmed diagnosis of FM completed an electronic diary that included once-daily assessments of positive affect and soft tissue pain. Multilevel modeling yielded a significant gene X environment interaction, such that individuals with met/met genotype on COMT experienced a greater decline in positive affect as daily pain increased than did either val/met or val/val individuals. A gene X environment interaction for OPRM1 also emerged, indicating that individuals with at least one asp allele were more resilient to elevations in daily pain than those homozygous for the asn allele. In sum, the findings offer researchers ample reason to further investigate the contribution of the catecholamine and opioid systems, and their associated genomic variants, to the still poorly understood experience of FM.
ContributorsFinan, Patrick Hamilton (Author) / Zautra, Alex (Thesis advisor) / Davis, Mary (Committee member) / Lemery-Chalfant, Kathryn (Committee member) / Presson, Clark (Committee member) / Arizona State University (Publisher)
Created2011
Description
Externalizing behaviors are pervasive, widespread, and disruptive across a multitude of settings and developmental contexts. While the conventional diathesis-stress model typically measures the disordered end of the spectrum, studies that span the range of behavior, from externalizing to competence behaviors, are necessary to see the full picture. To that end, this study examined the additive and nonadditive relations of a dimension of parenting (ranging from warm to rejecting), and variants in dopamine, vasopressin, and neuropeptide-y receptor genes on externalizing/competence in a large sample of predominantly Caucasian twin children in toddlerhood, middle childhood, and early adolescence. Variants within each gene were hypothesized to increase biological susceptibility to both negative and positive environments. Consistent with prediction, warmth related to lower externalizing/higher competence at all ages. Earlier levels of externalizing/competence washed out the effect of parental warmth on future externalizing/competence with the exception of father warmth in toddlerhood marginally predicting change in externalizing/competence from toddlerhood to middle childhood. Warmth was a significant moderator of the heritability of behavior in middle childhood and early adolescence such that behavior was less heritable (mother report) and more heritable (father report) in low warmth environments. Interactions with warmth and the dopamine and vasopressin genes in middle childhood and early adolescence emphasize the moderational role gene variants play in relations between the rearing environment and child behavior. For dopamine, the long variant related to increased sensitivity to parent warmth such that the children displayed more externalizing behaviors when exposed to rejection but they also displayed more competence behaviors when exposed to high warmth. Vasopressin moderation was only present under conditions of parental warmth, not rejection. Interactions with neuropeptide-y and warmth were not significant. The picture that emerges is one of gene-environment interplay, wherein the influence of both parenting and child genotype each depend on the level of the other. As genetic research moves forward, gene variants previously implicated as conferring risk for disorder should be reexamined in conjunction with salient aspects of the environment on the full range of the behavioral outcome of interest.
ContributorsO'Brien, T. Caitlin (Author) / Lemery-Chalfant, Kathryn (Thesis advisor) / Eisenberg, Nancy (Committee member) / Enders, Craig (Committee member) / Nagoshi, Craig (Committee member) / Arizona State University (Publisher)
Created2011
Description
The present study tested the factor structure of the externalizing disorders (e.g. attention-deficit hyperactivity disorder (ADHD), conduct disorder (SE), and substance experimentation (SE) ) in adolescence. In addition, this study tested the influence of the GABRA2 gene on the factors of the externalizing spectrum. Confirmatory factor analyses were used to test the factor structure of the externalizing spectrum. Specifically, three competing alternate confirmatory factor analytic models were tested: a one-factor model where all disorders loaded onto a single externalizing factor, a two-factor model where CD and SE loaded onto one factor and ADHD loaded onto another, and a three-factor model, where all three disorders loaded onto separate factors. Structural equation modeling was used to test the effect of a GABRA2 SNP, rs279858, on the factors of the externalizing spectrum. Analyses revealed that a three-factor model of externalizing disorders with correlated factors fit the data best. Additionally, GABRA2 had a significant effect on the SE factor in adolescence, but not on the CD or ADHD factors. These findings demonstrate that the externalizing disorders in adolescence share commonalities but also have separate sources of systematic variance. Furthermore, biological mechanisms may act as a unique etiological factor in the development of adolescent substance experimentation.
ContributorsWang, Frances L (Author) / Chassin, Laurie (Thesis advisor) / Lemery-Chalfant, Kathryn (Committee member) / Geiser, Christian (Committee member) / Arizona State University (Publisher)
Created2012
Description
I examined the role of children's or teacher's effortful control (EC) in children's academic functioning in early elementary school in two separate studies. In Study 1, I tested longitudinal relations between parents' reactions to children's displays of negative emotions in kindergarten, children's EC in first grade, and children's reading or math achievement in second grade (N = 291). In the fall of each school year, parents reported their positive or negative reactions and parents and teachers reported on children's EC. Standardized achievement tests assessed achievement each spring. Results from autoregressive panel mediation models demonstrated that constructs exhibited consistency across study years. In addition, first-grade EC mediated relations between parents' reactions (i.e., a difference composite of positive minus negative reactions) at kindergarten and second-grade math, but not reading, achievement. Findings suggest that one method of promoting math achievement in early school is through the socialization of children's EC. In Study 2, I examined relations between teachers' EC, teachers' reactions to children's negative emotions, the student-teacher relationship (STR), and children's externalizing behaviors or achievement among 289 second-graders and their 116 teachers. Results from mixed-model regressions showed that negative reactions and teacher-reported STR mediated relations between teachers' EC and math achievement. In addition, teacher-reported STR mediated links between teachers' EC and externalizing problems across reporters and between teachers' EC and reading achievement. Tests of moderated mediation indicated that a high-quality STR was negatively associated with externalizing problems and high levels of teachers' negative reactions were negatively related to math achievement only for students low in EC. In tests of moderation by social competence, teachers' reports of high-quality STRs tended to be negatively associated with externalizing problems, but relations were strongest for students not high in social competence. For students low in social competence only, children's reports of a high-quality STR was related to lower reading achievement. These results highlight the utility of considering whether and how teachers' own intrinsic characteristics influence classroom dynamics and students' academic functioning outcomes.
ContributorsSwanson, Jodi Michelle (Author) / Valiente, Carlos (Thesis advisor) / Bradley, Robert H (Thesis advisor) / Kochenderfer-Ladd, Becky (Committee member) / Lemery-Chalfant, Kathryn (Committee member) / Arizona State University (Publisher)
Created2011
Description
This study examines the relations among three aspects of temperament (shyness, impulsivity, and effortful control), resting respiratory sinus arrhythmia (RSA) recorded during a calming film and RSA suppression during three behavioral measures of effortful control, and adjustment (anxiety and externalizing behavior) in a sample of 101 preschool-age children. Principal components analysis was used to create composites for effortful control, shyness, impulsivity, anxiety, and externalizing behavior, and hierarchical regression analysis was used to test the study hypotheses. As expected, baseline RSA was negatively related to effortful control in shy children, but was unrelated to effortful control in children who were not shy. It was hypothesized that high baseline RSA would reduce the relation between shyness and anxiety, and between impulsivity and externalizing behavior; this hypothesis was supported for externalizing behavior, but not for anxiety. The interaction between impulsivity and RSA as a predictor of externalizing was statistically independent of effortful control, indicating that these are unique effects. Finally, it was hypothesized that RSA suppression would be positively related to effortful control for children low, but not high, in shyness. There was a marginal interaction between shyness and RSA suppression, with RSA suppression marginally negatively related to EC for children low in shyness, but unrelated to effortful control for children high in shyness; the direction of this association was opposite predictions. These findings indicate that RSA is more strongly related to effortful control for children high in shyness, and that it consequently may not be appropriate to use RSA as an index of EC for all children. This study also draws attention to the need to consider the context in which baseline RSA is measured because a true baseline may not be obtained for shy children if RSA is measured in an unfamiliar laboratory context. The finding that high RSA moderated (but did not eliminate) the relation between impulsivity and externalizing behavior is consistent with the conceptualization of RSA as a measure of self-regulation, but further research is needed to clarify the mechanism underlying this effect.
ContributorsSulik, Michael John (Author) / Eisenberg, Nancy (Thesis advisor) / Spinrad, Tracy L. (Committee member) / Lemery-Chalfant, Kathryn (Committee member) / Arizona State University (Publisher)
Created2012
Description
The purpose of this study was to examine whether maternal personality (i.e., Agreeableness and Conscientiousness) predicted maternal positive parenting (i.e., warmth/sensitivity and structure), and whether maternal parenting predicted children's regulation and sympathy and/or prosocial behavior. Additionally, the mediated effect of maternal warmth/sensitivity on the relation between maternal Agreeableness and children's regulation and the mediated effect of maternal structure on the relation between maternal Agreeableness and children's observed sympathy/prosocial behavior were investigated. Maternal personality was measured when children (N = 256 at Time 1) were 18 months old; maternal parenting was assessed when children were 18, 30, and 42 months old; children's regulation and sympathy/prosocial behavior (observed and reported) were assessed when children were 30, 42, and 54 months old. Mothers reported on their personality; maternal warmth/sensitivity was observed; maternal structure was observed and mothers also reported on their use of reasoning; mothers and caregivers rated children's regulation (i.e., effortful control [EC]) and regulation was also observed; mothers and fathers rated children's prosocial behavior; sympathy and prosocial behavior were also observed. In a path analysis, Conscientiousness did not significantly predict maternal warmth/sensitivity or structure at 30 months, whereas Agreeableness marginally predicted maternal warmth/sensitivity at 30 months and significantly predicted maternal structure at 30 months. Maternal warmth/sensitivity at 18 months significantly predicted 30-month EC, and 30-month maternal warmth/sensitivity significantly predicted 42-month EC. Maternal structure at 30 months significantly predicted 42-month observed sympathy/prosocial behavior. Maternal warmth/sensitivity at 42 months significantly predicted 54-month observed sympathy/prosocial behavior and marginally predicted 54-month reported prosocial behavior. Maternal structure and EC did not significantly predict reported prosocial behavior across any time point. EC did not significantly predict observed sympathy/prosocial behavior across any time point and maternal warmth/sensitivity at 18 and 30 months did not predict observed or reported sympathy/prosocial behavior at 30 or 42 months, respectively. Maternal Agreeableness directly predicted 30-month reported prosocial behavior and additional paths suggested possible bidirectional relations between maternal warmth/sensitivity and structure. Mediation analyses were pursued for two indirect relations; however, neither mediated effect was significant. Additional results are presented, and findings (as well as lack thereof) are discussed in terms of extant literature.
ContributorsEdwards, Alison (Author) / Eisenberg, Nancy (Thesis advisor) / Spinrad, Tracy L. (Thesis advisor) / Lemery-Chalfant, Kathryn (Committee member) / Bradley, Robert A. (Committee member) / Arizona State University (Publisher)
Created2015
Description
This study examined whether early adversity at 30-months moderated the heritability of common and individual components of EF at 8 years. It was hypothesized that early adversity would not moderate the common EF factor, but instead moderate individual EF components. The sample included 208 twin pairs from the Arizona Twin Project. Early Adversity, assessed at 30 months of age, included Parenting Daily Hassles, low perceived MOS social support, punitive punishment (Parental Responses to Child Misbehavior), home chaos (Confusion, Hubbub, and Order Scale), CES-D maternal depression, and low maternal emotional availability. EF at 8 years included the Eriksen Flanker Task, Continuous Performance Task, Digit Span Forward and Backward, and parent-reported Attentional Focusing and Inhibitory Control (Temperament in Middle Childhood Questionnaire). For both early adversity and EF, the first principal components were extracted as composites. A confirmatory factor analysis was also conducted to index common EF. Genetic analyses were tested on the common EF composites as well as each individual task using umx. Univariate models revealed genetic influences on all individual measures and common EF, with broad sense heritability from .22 (Digit Span Backwards) to .61 (parent-reported inhibitory control). Shared environmental influences were found for the Flanker Task (.13) and parent-reported inhibitory control (.24), and E was moderate to high (.40-.73) for all measures except parent-report inhibitory control (.15) and attentional focusing (.31). Moderation of heritability was not observed in for Digit Span Forward, Digit Span Backward, and Attentional Focusing. However, the nonshared environment was moderated for Common EF, and the Flanker Task, and additive genes and the nonshared environment were moderated for the Continuous Performance Task and Inhibitory Control. Generally, total variance decreased as early adversity increased, suggesting that homes with low levels of adversity may allow children to interact with more proximal processes that can promote EF development.
ContributorsRea-Sandin, Gianna (Author) / Lemery-Chalfant, Kathryn (Thesis advisor) / Elam, Kit (Committee member) / Bradley, Robert (Committee member) / Arizona State University (Publisher)
Created2018
Description
The tendency for psychopathology to aggregate within families is well-documented, though little is known regarding the level of specificity at which familial transmission of symptomology occurs. The current study first tested competing higher-order structures of psychopathology in adolescence, indexing general and more specific latent factors. Second, parent-offspring transmission was tested for broadband domain specificity versus transmission of a general liability for psychopathology. Lastly, genetic and environmental mechanisms underlying the familial aggregation of psychopathology were examined using nuclear twin-family models. The sample was comprised of five hundred adolescent twin pairs (mean age 13.24 years) and their parents drawn from the Wisconsin Twin Project. Twins and parents completed independent diagnostic interviews. For aim 1, correlated factors, bifactor, and general-factor models were tested using adolescent symptom count data. For aim 2, structural equation modeling was used to determine whether broadband domain-specific transmission effects were necessary to capture parent-offspring resemblance in psychopathology above and beyond a general transmission effect indexed by the latent correlation between a parental internalizing factor and offspring P-factor. For aim 3, general factor models were fitted in both generations, and factor scores were subsequently extracted and used in nuclear twin-family model testing. Results indicated that the bifactor model exhibited the best fit to the adolescent data. Familial aggregation of psychopathology was sufficiently accounted for by the transmission of a general liability. Lastly, the best fitting reduced nuclear twin-family model indicated that additive genetic, sibling-specific shared environmental, and nonshared environmental influences contributed to general psychopathology. Parent-offspring transmission was accounted for by shared genetics only, whereas co-twin aggregation was additionally explained by sibling-specific shared environmental factors. Results provide novel insight into the specificity and etiology of the familial aggregation of psychopathology.
ContributorsOro, Veronica (Author) / Lemery-Chalfant, Kathryn (Thesis advisor) / Chassin, Laurie (Committee member) / Doane, Leah D (Committee member) / Arizona State University (Publisher)
Created2019