Matching Items (16)

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Differences in Traditional and Non-Traditional Cardiovascular Disease Risk Factors between Asian and Non-Hispanic White Young Adults

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The objective of the present study was to investigate differences in traditional and non-traditional cardiovascular disease (CVD) risk factors between Asian and non-Hispanic White young adults. The burden of CVD

The objective of the present study was to investigate differences in traditional and non-traditional cardiovascular disease (CVD) risk factors between Asian and non-Hispanic White young adults. The burden of CVD varies by racial/ethnic group. Traditional risk factors that increase the likelihood of developing CVD include smoking, alcohol, physical inactivity, obesity, diabetes, high cholesterol, and high blood pressure. Suboptimal sleep is known to be a non-traditional risk factor for poor overall health, CVD risk factors, and CVD. The present study was an investigation of a cross-sectional, screening survey used for a larger community-based study on sleep and cardiovascular health. The unadjusted results examining differences in traditional CVD risk factors indicated that Asian participants were less likely to report alcohol use compared to non-Hispanic White participants. For non-traditional CVD risk factors, Asians were less likely to report experiencing sleep-related fatigue or malaise, attention impairment, daytime sleepiness, reduced motivation or energy, or concerns about their sleep compared to non-Hispanic White participants. Multivariate-analyses were conducted adjusting for sex and age. The adjusted results indicated that the Asian participants were less likely to report alcohol consumption, regular engagement in exercise, engagement in hard intensity exercise, concerns with sleep quality, and sleep difficulty-related fatigue, attention impairment, daytime sleepiness, reduced motivation, and were more likely to be obese compared to non-Hispanic White participants. The results may help guide cardiovascular prevention education provided to these groups. The data indicate the need for further longitudinal research studies on non-traditional CVD risk factors like sleep by ethnicity/race.

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  • 2017-12

Lessons Learned from the Halle Heart Museum: A Content Analysis of Student Letters

Description

The purpose of this study was to gain greater insight on the educational growth and experience of children who visit the Halle Heart Children's Museum, by analyzing and exploring student

The purpose of this study was to gain greater insight on the educational growth and experience of children who visit the Halle Heart Children's Museum, by analyzing and exploring student thank you letters received from 2011-2016. Of the major contributors of cardiovascular disease taught in the museum, nutrition was discussed about most in the letters (42.6%). Children are able to learn about health related topics in museums, as evidenced by recall of topics and facts in student letters. Museums can be an influential and education experience for children, especially museums teaching about health related topics.

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Date Created
  • 2017-12

Relationship Between Physical Activity, VLDL Lipoproteins, and T2DM Risk in Obese Latino Youth

Description

The purpose of this study was to examine the association between VLDL and diabetes risk factors, and the impact of a lifestyle intervention on VLDL levels in obese Latino youth.

The purpose of this study was to examine the association between VLDL and diabetes risk factors, and the impact of a lifestyle intervention on VLDL levels in obese Latino youth. Participants (N=160) in this study were taken from a lager diabetes prevention program for Latino adolescents (Age=14.8±0.8 years, BMI=98.2±1.4). Youth participated in a 12-week lifestyle intervention that included physical activity (60 minutes, 3x/week) and nutrition education sessions (60 minutes, 1x/week) that were delivered to families at the downtown Phoenix YMCA. Primary outcomes included VLDL and diabetes risk factors including fasting and 2-hour glucose and insulin which were measured at baseline and 12-weeks post-intervention. Baseline VLDL levels were significantly correlated with fasting insulin (r =.270, P<0.01) and youth who were more insulin resistant displayed higher VLDL levels compared to youth who were less insulin resistant derived from fasting insulin levels (M=29.8±14.7 mg/dl vs. M=21.6±9.6 mg/dl, P<0.01). In total, 77 participants completed the lifestyle intervention. At post-intervention, VLDL levels were significantly reduced (M=26.0±13.3 mg/dl to M=23.3±11.6 mg/dl, P=0.02). Culturally-grounded, community-based, family-focused lifestyle interventions are a promising approach for reducing cardiovascular disease risk factors in high-risk youth at risk for diabetes.

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  • 2018-12

Parental Approach to Cardiovascular Health Promotion & Prevention in Children

Description

Cardiovascular Disease (CVD) is the leading cause of death in the world today! More specifically, ischemic heart disease, also known as coronary artery disease, tops the world’s most deadly disease

Cardiovascular Disease (CVD) is the leading cause of death in the world today! More specifically, ischemic heart disease, also known as coronary artery disease, tops the world’s most deadly disease and is responsible for nearly 9 million deaths every year (World Health Organization, n.d.). This paper describes a Parental Approach to Cardiovascular Health Promotion and Prevention in children. The risk factors for CVD have been well established in adults and emerging evidence underline the importance of experiences and exposures on the consequent development of CVD. The aim of this project is to highlight the importance of early intervention in childhood by promoting cardiovascular health education and prevention in children. CVD is cause by a culmination of genetic and lifestyle factors and the many risk factors associated with cardiovascular disease is divided into two categories: those which are changeable or modifiable and those that are unchangeable or non-modifiable. The earlier that parents address the modifiable risk factors, the better the child’s outcome of preventing heart disease in adulthood. Therefore, alternative means of a healthy dietary approach such as the 5-2-1-0 program in addition to exercising is extremely crucial. This paper will discuss the different preventative strategies and ways to mitigate symptoms of CVD. Therefore, I have developed a 4-step outline for cardiovascular health education and prevention strategies which parents can use when raising their children.

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  • 2020-05

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The Relationship Between Corn Flour and Cardiometabolic and Inflammatory Disease Markers in Adults with Hyperlipidemia

Description

Since 1975, the prevalence of obesity has nearly tripled around the world. In 2016, 39% of adults, or 1.9 billion people, were considered overweight, and 13% of adults, or 650

Since 1975, the prevalence of obesity has nearly tripled around the world. In 2016, 39% of adults, or 1.9 billion people, were considered overweight, and 13% of adults, or 650 million people, were considered obese. Furthermore, Cardiovascular disease remains to be the leading cause of death for adults in the United States, with 655,000 people dying from related conditions and consequences each year. Including fiber in one’s dietary regimen has been shown to greatly improve health outcomes in regards to these two areas of health. However, not much literature is available on the effects of corn-based fiber, especially detailing the individual components of the grain itself. The purpose of this preliminary study was to test the differences in influence on both LDL-cholesterol and triglycerides between treatments based on whole-grain corn flour, refined corn flour, and 50% refined corn flour + 50% corn bran derived from whole grain cornmeal (excellent fiber) in healthy overweight (BMI ≥ 25.0 kg/m2) adults (ages 18 - 70) with high LDL cholesterol (LDL ≥ 120mg/dL). 20 participants, ages 18 - 64 (10 males, 10 females) were involved. Data was derived from blood draws taken before and after each of the three treatments as well as before and after each treatment’s wash out periods. A general linear model was used to assess the effect of corn products on circulating concentrations of LDL-cholesterol and triglycerides. From the model, it was found that the whole-grain corn flour and the 50% refined corn flour + 50% corn bran drive from whole grain cornmeal treatments produced a higher, similar benefit in reductions in LDL-cholesterol. However, the whole grain flour, refined flour, and bran-based fiber treatments did not influence the triglyceride levels of the participants throughout this study. Further research is needed to elucidate the effects of these fiber items on cardiometabolic disease markers in the long-term as well as with a larger sample size.

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  • 2021-05

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A rapid and Label-free IL-18 point-of-care biosensor for CVD detection

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Development of a rapid and label-free Electrochemical Impedance Spectroscopy (EIS) biosensor for Cardiovascular Disease (CVD) detection based on Inerluekin-18 (IL-18) sensitivity was proposed to fill the technology gap between rapid

Development of a rapid and label-free Electrochemical Impedance Spectroscopy (EIS) biosensor for Cardiovascular Disease (CVD) detection based on Inerluekin-18 (IL-18) sensitivity was proposed to fill the technology gap between rapid and portable CVD point-of-care diagnosis. IL-18 was chosen for this CVD biosensor due to its ability to detect plaque vulnerability of the heart. Custom (hand) made sensors, which utilized a three electrode configuration with a gold disk working electrode, were created to run EIS using both IL-18 and anti-IL-18 molecules in both purified and blood solutions. The EIS results for IL-18 indicated the optimal detection frequency to be 371Hz. Blood interaction on the working electrode increased the dynamic range of impedance values for the biosensor. Future work includes Developing and testing prototypes of the biosensor along with determining if a Nafion based coating on the working electrode will reduce the dynamic range of impedance values caused by blood interference.

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  • 2013-05

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Electrically Conductive Hydrogel-Based Topographies for Development of Three Dimensional (3D) Cardiac Tissues

Description

Cardiac tissue engineering is an emerging field that has the potential to regenerate and repair damaged cardiac tissues after myocardial infarction. Numerous studies have introduced hydrogel-based cardiac tissue constructs featuring

Cardiac tissue engineering is an emerging field that has the potential to regenerate and repair damaged cardiac tissues after myocardial infarction. Numerous studies have introduced hydrogel-based cardiac tissue constructs featuring suitable microenvironments for cell growth along with precise surface topographies for directed cell organization. Despite significant progress, previously developed cardiac tissue constructs have suffered from electrically insulated matrices and low cell retention. To address these drawbacks, we fabricated micropatterned hybrid hydrogel constructs (uniaxial microgrooves with 50 µm with) using a photocrosslinkable gelatin methacrylate (GelMA) hydrogel incorporated with gold nanorods (GNRs). The electrical impedance results revealed a lower impedance in the GelMA-GNR constructs versus the pure GelMA constructs. Superior electrical conductivity of GelMA-GNR hydrogels (due to incorporation of GNRs) enabled the hybrid tissue constructs to be externally stimulated using a pulse generator. Furthermore, GelMA-GNR tissue hydrogels were tested to investigate the biological characteristics of cultured cardiomyocytes. The F-actin fiber analysis results (area coverage and alignment indices) revealed higher directed (uniaxial) cytoskeleton organization of cardiac cells cultured on the GelMA-GNR hydrogel constructs in comparison to pure GelMA. Considerable increase in the coverage area of cardiac-specific markers (sarcomeric α-actinin and connexin 43) were observed on the GelMA-GNR hybrid constructs compared to pure GelMA hydrogels. Despite substantial dissimilarities in cell organization, both pure GelMA and hybrid GelMA-GNR hydrogel constructs provided a suitable microenvironment for synchronous beating of cardiomyocytes.

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Date Created
  • 2016-05

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In Vitro and In Silico Study of Hemodynamics In Vascular Models: Validating Computational Fluid Dynamics for Medical Application

Description

This study investigates the application of Computational Fluid Dynamics (CFD) to the medical field. An overview of recent advances in computational simulation and modeling in medical applications is provided, with

This study investigates the application of Computational Fluid Dynamics (CFD) to the medical field. An overview of recent advances in computational simulation and modeling in medical applications is provided, with a particular emphasis on CFD. This study attempts to validate CFD and demonstrate the possibility for applying CFD to the clinical treatment and evaluation of atherosclerotic disease. Three different geometric configurations are investigated: one idealized bifurcation with a primary diameter of 8 mm, and two different patient-specific models of the bifurcation from the common femoral artery to the superficial and deep femoral arteries. CFD is compared against experimental measurements of steady state and pulsatile flow acquired with Particle Image Velocimetry (PIV). Steady state and pulsatile flow rates that are consistent with those observed in the femoral artery are used. In addition, pulsatile CFD simulations are analyzed in order to demonstrate meaningful clinical applications for studying and evaluating the treatment of atherosclerotic disease. CFD was successfully validated for steady state flow, with an average percent error of 6.991%. Potential for validation was also demonstrated for pulsatile flow, but methodological errors warrant further investigation to reformulate methods and analyze results. Quantities frequently associated with atherosclerotic disease and arterial bifurcations, such as large variations in wall shear stress and the presence of recirculation zones are demonstrated from the pulsatile CFD simulations. Further study is required in order to evaluate whether or not such phenomena are represented by CFD accurately. Further study must also be performed in order to evaluate the practicality and utility of CFD for the evaluation of atherosclerotic disease treatment.

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  • 2016-05

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Acculturative Stress and the Risk of Cardiovascular Disease in Korean Americans

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The purpose of this study was to determine if a relationship existed between acculturative stress and cardiovascular disease risk factors in Korean immigrants residing in the United States. This is

The purpose of this study was to determine if a relationship existed between acculturative stress and cardiovascular disease risk factors in Korean immigrants residing in the United States. This is a secondary analysis of existing data that was collected for a cross-sectional, descriptive study of 104 Korean American adults in a large Southwestern city in the U.S. Descriptive statistics, t-test, and analysis of variance were used to analyze data on demographics, acculturative stress, and biomarkers indicative of cardiovascular risk, such as body mass index (BMI), blood pressure (BP), and total cholesterol (TC). Most participants were women (66.3%), with a mean age of 53.59 (SD = 10.42), who were married (89.4%), educated at a college level or above (graduate) level (85.6%), employed full/part-time (64.4%), and had an annual household income of $50,000 or more (62.5%). The average length of residence in the U.S. was 22.04 years (SD = 11.89), Half of the study sample were overweight or obese (BMI > 23 kg/m2), 65.4% with high SBP (≥ 120 mmHg), 75.9% with high DBP (≥ 80 mmHg), and 75% with high TC (≥ 170 mg/dL). Acculturative stress was significantly associated with age, length of residence, and family annual income. Cardiovascular risk factors were significantly different by age, gender, marital status, education level, or employment status. However, the relationship between acculturative stress and cardiovascular risk indicators was not statistically significant. The study findings provide useful information about demographic characteristics, acculturative stress, and cardiovascular health of Korean immigrants in the United States. In order to prevent and manage cardiovascular health of the population, healthcare professionals should consider that cardiovascular risk factors may vary according to demographic characteristics in Korean immigrants.

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Date Created
  • 2016-05

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The Role of Nutrition Therapy in the Treatment of Cardiovascular Disease

Description

In the United States, cardiovascular disease remains the number one cause of death. The most prevalent risk factor for cardiovascular disease is poor nutrition and thus, proper nutrition is often

In the United States, cardiovascular disease remains the number one cause of death. The most prevalent risk factor for cardiovascular disease is poor nutrition and thus, proper nutrition is often used as a preventative measure. With the expensive and often ineffective medications and procedures currently being used to treat cardiovascular disease, we need to find a better solution. One promising solution is nutrition therapy, which is the implementation of proper nutrition guidelines into the treatment plan of patients with cardiovascular disease. After close research and analysis of four popular diets, a vegan (plant-based) diet, vegetarian diet, and Mediterranean diet could offer improvement of cardiovascular disease risk factors and chances of cardiovascular disease mortality. Different ways to start implementing nutrition therapy in medicine include emphasizing nutrition education in medical school and/or including registered dietitians in the treatment process for cardiovascular disease patients.

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Date Created
  • 2020-05