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In which industry that has ever been profit generating, does a firm profit from their failure? The United States has a mass incarceration problem. With 25% of the world prison population residing in the US, spending on detention costs the US government $80 billion annually. Over 50% of the individuals

In which industry that has ever been profit generating, does a firm profit from their failure? The United States has a mass incarceration problem. With 25% of the world prison population residing in the US, spending on detention costs the US government $80 billion annually. Over 50% of the individuals incarcerated in America are of black or Latino descent. This massive growth in the incarcerated population of America began in the 1970s and with the passive support of American citizens has created an industry whose players profit from the detention of people. Currently, the privately run detention facilities in the United States hold 7% of state prisoners, 18% of federal prisoners, and nearly 75% of ICE's undocumented detainee population. The detention of people for profit is an idea rooted in the same profit motive that allowed the institution of slavery to flourish. However even after the 13th Amendment abolished slavery in the U.S., the oppressive forces behind slave-era economics have been perpetuated through legislation and policies that continued the stratification of society and reinforcement of the social order. With the help of corporate lobbyists, political action committees, and organizations such as the American Legislative Exchange Council, the corporate shareholders of private prisons, such as CoreCivic and The GEO Group, are able to directly align their profit-driven interests with those of federal and state legislators. By the incorporation of legislation and policy into state and federal law, the shareholders of private prisons are able to directly affect legislation as well as their own potential for profit. The justification for the usage of private prisons is thought to be seen in the price savings and flexibility that it provides for federal and state governments. However, due to the law enforcement contractor's exemption from public record laws, there is no clear evidence of where the cost savings occur, or even if there are cost savings at all. Is it ethical for a for-profit-prison corporation to be responsible for the care, security, and rehabilitation of an individual, when if they fail to rehabilitate the individual, it will add to the number of inmates under their control? The measure of a prison's failure to rehabilitate an inmate is considered the recidivism rate, and is affected when an inmate leaves a detention facility, commits another crime, then is arrested. This profit motive is causing our society to incarcerate increasing numbers of people in private prisons. For-profit prisons financially benefit from long-term incarceration and recidivism. The passive investments from public and private employees and institutions through investment corporations are the legs that allow the private prison industry to stand. Twenty-nine investment firms, such as The Vanguard Group and Fidelity Investments, own nearly two-thirds of the two largest players in the private prison industry. This includes the passive investments by public institutions such as the Arizona State University Foundation's $600 million endowment fund as well as the $500 million directly invested into CoreCivic and GEO Group from the University of Texas/ Texas A&M Investment Management Company. The goal of abolishing private prisons will require years of litigation against the giants of the industry as well as the governmental entities supporting them. However, we can start today by demanding divestiture by our school and similar institutions as well continuing to share the knowledge of the oppressive forces associated with the detention of individuals for profit.
ContributorsBayham, Michael (Author) / Gomez, Alan (Thesis director) / Dacey, John (Committee member) / W.P. Carey School of Business (Contributor) / Department of Supply Chain Management (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Education, with emphasis on post secondary education, should become a top priority for policy makers with regards to the criminal justice system in the United States. Criminal justice funding within the United States is being applied increasingly to factors that correlate with high rates of recidivism such as housing increased

Education, with emphasis on post secondary education, should become a top priority for policy makers with regards to the criminal justice system in the United States. Criminal justice funding within the United States is being applied increasingly to factors that correlate with high rates of recidivism such as housing increased numbers of inmates. Research strongly supports education in the mitigation of the rate of recidivism. Reducing the rate of recidivism helps to create a more sustainable influx of inmates into correctional facilities. Those who enter into prison are some of the most economically disadvantaged individuals in the United States. In comparison to the general population, the prison population has significantly lower formal education levels and lower literacy levels. Without access to an education, inmates have the greater struggle to reach economic livelihood. Limited access to education perpetuates a cycle of inequality and injustice and can contribute to high recidivism rates. Recidivism drives up the costs of taxpayer dollars. Effective means for integrating inmates into society, such as basic literacy training and access to post secondary educational programs, must be expanded on and implemented.
ContributorsAbraham, Kristen (Author) / Robertson, Sherry (Thesis director) / Bruhn, Karen (Committee member) / Ribeiro, Michelle (Committee member) / Barrett, The Honors College (Contributor)
Created2012-05
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Description
Bexarotene is a commercially produced drug commonly known as Targetin presecribed to treat cutaneous T-cell lymphoma (CTCL). Bex mimics the actions of natural 9-cis retinoic acid in the body, which are derived from Vitamin A in the diet and boost the immune system. Bex has been shown to be effective

Bexarotene is a commercially produced drug commonly known as Targetin presecribed to treat cutaneous T-cell lymphoma (CTCL). Bex mimics the actions of natural 9-cis retinoic acid in the body, which are derived from Vitamin A in the diet and boost the immune system. Bex has been shown to be effective in the treatment of multiple types of cancer, including lung cancer. However, the disadvantages of using Bex include increased instances of hypothyroidism and excessive concentrations of blood triglycerides. If an analog of Bex can be developed which retains high affinity RXR binding similar to the 9-cis retinoic acid while exhibiting less interference for heterodimerization pathways, it would be of great clinical significance in improving the quality of life for patients with CTCL. This thesis will detail the biological profiling of additional novel (Generation Two) analogs, which are currently in submission for publication, as well as that of Generation Three analogs. The results from these studies reveal that specific alterations in the core structure of the Bex "parent" compound structure can have dramatic effects in modifying the biological activity of RXR agonists.
ContributorsYang, Joanna (Author) / Jurutka, Peter (Thesis director) / Wagner, Carl (Committee member) / Hibler, Elizabeth (Committee member) / Barrett, The Honors College (Contributor)
Created2012-05
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Bexarotene (Targretin®) is an FDA approved drug used to treat cutaneous T-cell lymphoma (CTCL), as well as off-label treatments for various cancers and neurodegenerative diseases. Previous research has indicated that bexarotene has a specific affinity for retinoid X receptors (RXR), which allows bexarotene to act as a ligand-activated-transcription factor

Bexarotene (Targretin®) is an FDA approved drug used to treat cutaneous T-cell lymphoma (CTCL), as well as off-label treatments for various cancers and neurodegenerative diseases. Previous research has indicated that bexarotene has a specific affinity for retinoid X receptors (RXR), which allows bexarotene to act as a ligand-activated-transcription factor and in return control cell differentiation and proliferation. Bexarotene targets RXR homodimerization to drive transcription of tumor suppressing genes; however, adverse reactions occur simultaneously when bound to other nuclear receptors. In this study, we used novel bexarotene analogs throughout 5 iterations synthesized in the laboratory of Dr. Wagner to test for their potency and ability to bind RXR. The aim of our study is to quantitatively measure RXR homodimerization driven by bexarotene analogs using a yeast two-hybrid system. Our results suggests there to be several compounds with higher protein activity than bexarotene, particularly in generations 3.0 and 5.0. This higher affinity for RXR homodimers may help scientists identify a compound that will minimize adverse effects and toxicity of bexarotene and serve as a better cancer treatment alternative.
ContributorsSeto, David Hua (Author) / Marshall, Pamela (Thesis director) / Wagner, Carl (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Natural Sciences (Contributor) / School of Social and Behavioral Sciences (Contributor)
Created2015-05
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A music therapy informed music group program was created and implemented at the Maricopa Reentry Center in Phoenix. This program \u2014 entitled Building Hope Through Music \u2014 utilized music therapy techniques including lyric analysis, songwriting, singing, musical games, and guided visualization in order to improve self-awareness, provide a medium for

A music therapy informed music group program was created and implemented at the Maricopa Reentry Center in Phoenix. This program \u2014 entitled Building Hope Through Music \u2014 utilized music therapy techniques including lyric analysis, songwriting, singing, musical games, and guided visualization in order to improve self-awareness, provide a medium for self-expression, increase teamwork and collaboration, promote relaxation, facilitate emotional processing and awareness, and improve tolerance of non-preferred activities in participants. This group was conducted for seven months and had participation from over 400 male ex-offenders.
ContributorsQuirbach, Rachel Marie (Author) / Wright, Kevin (Thesis director) / Thompson, Jason (Committee member) / Belgrave, Melita (Committee member) / School of Criminology and Criminal Justice (Contributor) / School of Music (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Description
Bexarotene (Bex) is a FDA-approved drug used to treat cutaneous T-cell lymphoma (CTCL). It binds with high affinity to the retinoid-X-receptor (RXR), a nuclear receptor implicated in numerous biological pathways. Bex may have the potential to attenuate estrogenic activity by acting as an estrogen receptor alpha (ERα) signaling antagonist, and

Bexarotene (Bex) is a FDA-approved drug used to treat cutaneous T-cell lymphoma (CTCL). It binds with high affinity to the retinoid-X-receptor (RXR), a nuclear receptor implicated in numerous biological pathways. Bex may have the potential to attenuate estrogenic activity by acting as an estrogen receptor alpha (ERα) signaling antagonist, and can therefore be used to treat ERα-positive cancers, such as breast cancer. Using dual luciferase reporter assays, real-time qRT-PCR, and metabolic proliferation assays, the anti-estrogenic properties of Bex were ascertained. However, since Bex produces numerous contraindications, select novel RXR drug analogs were also evaluated. Results revealed that, in luciferase assays, Bex could significantly (P < 0.01) inhibit the transcriptional activity of ERα, so much so that it rivaled ER pan-antagonist ZK164015 in potency. Bex was also able to suppress the proliferation of two breast cancer cell models, MCF-7 and T-47D, and downregulate the expression of an estrogen receptor target gene (A-myb), which is responsible for cell proliferation. In addition, novel analogs A30, A33, A35, and A38 were evaluated as being more potent at inhibiting ERE-mediated transcription than Bex at lower concentrations. Analogs A34 and A35 were able to suppress MCF-7 cell proliferation to a degree comparable to that of Bex. Inhibition of T-47D cell proliferation, by contrast, was best achieved by analogs A34 and A36. For those with ERα – positive breast cancer who are refractory to current chemotherapeutics used to treat breast cancer, Bex and its analogs may prove to be useful alternative options.
ContributorsBains, Supreet (Author) / Jurutka, Peter (Thesis director) / Hackney Price, Jennifer (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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The author examines drug court as a means to reduce recidivism rates for individuals who are addicted to illegal substances. The thesis analyzes the best practices for drug courts in treating addiction and lowering recidivism. In conducting this analysis, the author focuses on the Yuma County Drug Court Program (YCDC).

The author examines drug court as a means to reduce recidivism rates for individuals who are addicted to illegal substances. The thesis analyzes the best practices for drug courts in treating addiction and lowering recidivism. In conducting this analysis, the author focuses on the Yuma County Drug Court Program (YCDC). After discussing the major components of the YCDC program, the author reaches several conclusions about the program. The author's conclusions are based in part on a study analyzing the recidivism rates for individuals who participated in YCDC from January 1, 2007 through December 31, 2010. The author concludes that an effective drug court program requires proper screening and assessment using validated assessment tools that ensure delivery of treatment to individuals with high substance abuse treatment needs. In addition, drug courts must include counseling in both sober individual and group settings, cognitive restructuring, life skills training, and frequent interaction with the drug court judge. The author also concludes that drug courts are more successful when they stress accountability and independence by requiring participants to maintain a stable residence and employment. In YCDC these practices lead to 48.4% of individuals participating in the 18-month program having no criminal justice involvement for a period of three years after their exit from the program. Other important outcomes showed that well over 90% of the participants' drug tests were negative and 87% of the participants were employed. The author concludes that the YCDC program provides a good model for drug courts seeking to lower recidivism.
ContributorsGould, Anna Elaine (Author) / Chisum, Jack (Thesis director) / Carr, Natasha (Committee member) / School of Nutrition and Health Promotion (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Recidivism rates in the United States are alarmingly high. The vast number of inmates who re- offend upon release and re-enter into correctional facilities upsets people and many individuals focus their blame on the private and public prisons. Currently, the research that is available on private and public prisons is

Recidivism rates in the United States are alarmingly high. The vast number of inmates who re- offend upon release and re-enter into correctional facilities upsets people and many individuals focus their blame on the private and public prisons. Currently, the research that is available on private and public prisons is unpersuasive because it creates a harsh polarization between the two prison systems. The benefits as well as the detriments of each sector are explained in great detail, but all of the current research is lacking one thing: insider experience. The majority of the available research is conducted by people behind a computer screen or behind the binding of a book. While a wide variety of different articles, short stories, and journals have been published and are readily available to eager readers and researchers, these arguments repeat themselves and fail to weigh the complex merits of each system against the other; specifically, each body of work is lacking knowledge from people who have experienced both private and public prisons from an internal perspective. To compensate for this lack of ethnographic research, the current study allows the reader to get an internal perspective of public and private prisons. This was done by interviewing two wardens who have served on the federal, state, and private levels as well as touring a private correctional facility in Arizona. These experiences paved the way for novel research to be conducted and was used as a tool to weave the complicated web of private and public prisons in the United States. Findings, interviews, and ideas for the future of prisons are discussed.
ContributorsTometich, Drake (Author) / Wright, Kevin (Thesis director) / Young, Jacob (Committee member) / School of Criminology and Criminal Justice (Contributor) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Prison re-entry is a complicated process and is associated with a number of challenges for offenders to overcome. Unfortunately, many are not successful at navigating this process, and consequently, recidivism is a prevalent concern within the criminal justice system. These concerns are problematic with drug offenders, specifically, as this grou

Prison re-entry is a complicated process and is associated with a number of challenges for offenders to overcome. Unfortunately, many are not successful at navigating this process, and consequently, recidivism is a prevalent concern within the criminal justice system. These concerns are problematic with drug offenders, specifically, as this group is a quite pervasive component of the correctional population in America and one that tends to face more difficult experiences with reintegrating into society. In addition, a substantial need for substance abuse treatment in the community is in place for these offenders, yet is not necessarily readily available. This study examines the accessibility and nature of such treatment through the use of interviews with community treatment providers. It also assesses the barriers offenders face accessing help as well as potential solutions to these obstacles. The findings suggest that independence, support networks, resistance to treatment, motivation to change, rule conformity, mental illness, institutionalization, a lack of resources, and restrictions within the agencies that provide treatment are all significant factors in recovery. The results then demonstrate that treatment providers are able to provide incentives to bolster motivation, encourage healthy mindsets, help gain access to the resources that are available, and validate success through celebration in order to overcome these difficulties. The study may be limited by a potentially non-generalizable sample and a lack of specificity could be addressed by more expansive but focused research in the future as well as financial analyses to raise awareness regarding the severity of the situation.
ContributorsJohnson, Nicole Jolene (Author) / Chamberlain, Alyssa (Thesis director) / Wright, Kevin (Committee member) / School of Criminology and Criminal Justice (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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Education is a fundamental human right. However, when groups of people are subjugated to systematic violence and institutionalization, the importance of education often is often forgotten. A team of students and faculty at Arizona State University (ASU) currently teach an Introduction to Psychology course within a minimum-security unit in conjunction

Education is a fundamental human right. However, when groups of people are subjugated to systematic violence and institutionalization, the importance of education often is often forgotten. A team of students and faculty at Arizona State University (ASU) currently teach an Introduction to Psychology course within a minimum-security unit in conjunction with both the Arizona Department of Corrections and the Prison Education Program at ASU. This course aims to enhance the current educational programs offered by the prison by fostering an environment where inmates can practice literacy skills and are introduced to standard classroom procedures for the typical university class. In addition, the course introduces students to an academic field previously unknown to them, specifically, psychology. However, the most important aspect of this educational endeavor is to provide an environment where people who have been deemed inhuman and outside of the human experience can come together and learn. By doing so, the curriculum sought to instill confidence in the students by demonstrating that they are in fact capable of learning and comprehending university level material. As of 2016, numerous studies have been conducted from across the nation that have reaffirmed the validity and efficacy of prison education on reducing recidivism levels of the previously incarcerated (ADC 2005, Kim & Clark 2013, Nuttal et al. 2003). Additionally, studies have determined that the benefits that students receive from education while incarcerated are, over time, shared with the family members (Erisman & Contardo, 2005). These benefits, while not strictly educational, are incredibly important within the realm of reduction in crime as they pertain to "reduction of costs, reduction of strain of offenders on their families, and an economic boost for society" (Erisman & Contardo, 2005). Teaching within any prison unit, regardless of the security level, provides a variety of unique challenges. Some of these include the lack of technological resources within most classrooms, prohibition of outside material unless vetted and approved by prison education staff, and rigid restrictions on student-teacher interactions. Also, because of the nature of psychology and the students within the class, certain sensitive topics must be either handled with extreme care or will not be covered at all. However, particular achievements were made in regards to increasing in class participation and encouraging the students to continue to pursue academics. Most importantly, it provides an environment where the humanity of the prisoner is restored, if but for only a few hours a week. It allows them to be seen as more than numbers, allows them to think and voice their opinions in a space that respects them for their beliefs. And the restoration of humanity to an inherently inhumane system is far more important than any other educational goal.
ContributorsLeith, Kaitlyn Lee (Author) / Amazeen, Eric (Thesis director) / Cavanaugh Toft, Carolyn (Committee member) / Department of Psychology (Contributor) / Department of English (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12