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- Creators: Dixon, Maria
- Creators: School of International Letters and Cultures
- Resource Type: Text
Description
The use of functional magnetic resonance imaging (fMRI) has been increasing in popularity due to its ability to measure brain activity during presentation of stimuli. Blood flow responses in the brain occur when a stimulus is presented and can be measured using fMRI. The delay of onset of this blood flow response can vary due to distances from the heart to the brain blood vessels. This variability causes differences in onset and time to peak blood flow response across the brain that is not currently predictable. To account for this, statistical analyses add the response's temporal derivative to regression models. Derived from the Taylor series expansion, the temporal derivative corrects for small variations in the time delay for the blood flow response (i.e. less than 1 second or so). However, I show that inclusion of the temporal derivative in analyses increases false positive rates. I conducted fMRI analyses on data collected as participants complete motor responses and on resting state data. Analyses were repeated both with and without inclusion of the temporal derivative. More significant responses were found with inclusion of the temporal derivative in both cases, suggesting possible increases in false positive rates. The goal of the present study is to increase awareness of the current fMRI data analysis practices and their potential flaws.
ContributorsTemporini, Victoria (Author) / McClure, Samuel (Thesis director) / Glenberg, Arthur (Committee member) / Elliott, Blake (Committee member) / Department of Psychology (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2018-12
Description
In this pilot study, the purpose was to determine if certain language interventions could help bilingual children reduce maze use and improve their story retell abilities. We used language intervention, Story Champs, and its Spanish version, Puente de Cuentos to help bilingual children improve their story retell abilities. We conducted the intervention over the course of three days in both Spanish and English. The children participated in three stories in each language each day. They also received a narrative measure before and after the intervention to measure gains in story ability and to measure maze use. Results of the study indicated that there were no statistically-significant differences in the children's story retell abilities or maze use before and after the intervention. Nevertheless, we are encouraged by our results for future further study because of some improvements the children made.
ContributorsWhiteley, Aaron Kyle (Author) / Restrepo, Maria (Thesis director) / Dixon, Maria (Committee member) / Department of Speech and Hearing Science (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
This pilot study evaluated whether Story Champs and Puente de Cuentos helped bilingual preschoolers increase their usage of emotional terms and ability to tell stories. Participants in this study included 10 Spanish-English bilingual preschoolers. Intervention was conducted in 9 sessions over 3 days using the Test of Narrative Retell to measure results. Results did not find significant gains in either emotional term usage or ability to tell stories, but the results were promising as a pilot study.
ContributorsSato, Leslie Mariko (Author) / Restrepo, Maria (Thesis director) / Dixon, Maria (Committee member) / Department of Speech and Hearing Science (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
Individuals with autism spectrum disorder (ASD) are known to show impairments in various domains of executive function (EF) such as behavioral flexibility or inhibitory control. Research suggests that EF impairment in adults with ASD may relate to ASD core symptoms, restrictive behaviors and social communication deficits. Mindfulness-based stress reduction (MBSR) has shown promise for improving EF abilities in neurotypical adults, but research has not explored its efficacy or neural mechanisms in adults with ASD. This pilot study examines the effects of an 8-week MBSR intervention on self-report measures of EF and resting-state functional connectivity in a sample of adults with ASD. Fifty-four participants were assigned either to an MBSR group (n = 29) or a social support group (n = 25). Executive function was measured using the BRIEF-2 before and after the intervention for the twenty-seven participants in the second cohort. MBSR-specific improvements in EF were found for BRIEF measures of initiation, inhibition, and working-memory. Resting-state fMRI data was analyzed using independent component analysis (ICA), and group by time resting-state functional connectivity differences were observed between the cerebellar network and frontal regions including the right frontal pole (rFP), medial frontal cortex (MFC) and left and right superior frontal gyri (SFG). The MBSR group showed increases in functional connectivity between the cerebellum and EF regions which correlated with improvements in BRIEF-2 measures. These findings suggest that MBSR may improve EF domains in adults with ASD, and that increases in functional connectivity between the cerebellum and frontal regions while at rest may be a mechanism for such improvements.
ContributorsGuerithault, Nicolas (Author) / Braden, B. Blair (Thesis advisor) / Rogalsky, Corianne (Committee member) / Dixon, Maria (Committee member) / Arizona State University (Publisher)
Created2021
Description
Early identification of dyslexia is essential to providing children with the necessary services and support to succeed academically. Current dyslexia screening measures are not widely available for English-speaking monolingual children and those available for bilingual children are not widely used. To contribute to the effort to provide widely available screening for six-year-old English speaking and bilingual children, the ASU Bilingual Language and Literacy Lab, the Child Language and Literacy Lab, Learning to Soar Tutoring, Healing Hearts Pediatrics, and the Phoenix Children’s hospital have collaborated to develop the Dyslexia Screening Questionnaire (DysQ) that is offered in both English and Spanish. The goal of this study (Phase I) was to test the readability and comprehensibility of the DySQ to help ensure that it is accessible to a wide population of English and Spanish-speaking parents. In the second phase of the study, we aim to validate the DySQ by comparing the DySQ results with gold-standard testing for diagnosing dyslexia. The ultimate goal is to implement the DySQ into pediatric settings so that English and Spanish-speaking children may be screened for dyslexia at their 6-year-old well-child check-up.
ContributorsSwartz, Kathleen (Author) / Restrepo, Laida (Thesis director) / Gray, Shelley (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor) / School of International Letters and Cultures (Contributor)
Created2021-12