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Description
Frequency effects favoring high print-frequency words have been observed in frequency judgment memory tasks. Healthy young adults performed frequency judgment tasks; one group performed a single task while another group did the same task while alternating their attention to a secondary task (mathematical equations). Performance was assessed by correct and error responses, reaction times, and accuracy. Accuracy and reaction times were analyzed in terms of memory load (task condition), number of repetitions, effect of high vs. low print-frequency, and correlations with working memory span. Multinomial tree analyses were also completed to investigate source vs. item memory and revealed a mirror effect in episodic memory experiments (source memory), but a frequency advantage in span tasks (item memory). Interestingly enough, we did not observe an advantage for high working memory span individuals in frequency judgments, even when participants split their attention during the dual task (similar to a complex span task). However, we concluded that both the amount of attentional resources allocated and prior experience with an item affect how it is stored in memory.
ContributorsPeterson, Megan Paige (Author) / Azuma, Tamiko (Thesis advisor) / Gray, Shelley (Committee member) / Liss, Julie (Committee member) / Arizona State University (Publisher)
Created2013
Description
Specific dendritic morphologies are a hallmark of neuronal identity, circuit assembly, and behaviorally relevant function. Despite the importance of dendrites in brain health and disease, the functional consequences of dendritic shape remain largely unknown. This dissertation addresses two fundamental and interrelated aspects of dendrite neurobiology. First, by utilizing the genetic power of Drosophila melanogaster, these studies assess the developmental mechanisms underlying single neuron morphology, and subsequently investigate the functional and behavioral consequences resulting from developmental irregularity. Significant insights into the molecular mechanisms that contribute to dendrite development come from studies of Down syndrome cell adhesion molecule (Dscam). While these findings have been garnered primarily from sensory neurons whose arbors innervate a two-dimensional plane, it is likely that the principles apply in three-dimensional central neurons that provide the structural substrate for synaptic input and neural circuit formation. As such, this dissertation supports the hypothesis that neuron type impacts the realization of Dscam function. In fact, in Drosophila motoneurons, Dscam serves a previously unknown cell-autonomous function in dendrite growth. Dscam manipulations produced a range of dendritic phenotypes with alteration in branch number and length. Subsequent experiments exploited the dendritic alterations produced by Dscam manipulations in order to correlate dendritic structure with the suggested function of these neurons. These data indicate that basic motoneuron function and behavior are maintained even in the absence of all adult dendrites within the same neuron. By contrast, dendrites are required for adjusting motoneuron responses to specific challenging behavioral requirements. Here, I establish a direct link between dendritic structure and neuronal function at the level of the single cell, thus defining the structural substrates necessary for conferring various aspects of functional motor output. Taken together, information gathered from these studies can inform the quest in deciphering how complex cell morphologies and networks form and are precisely linked to their function.
ContributorsHutchinson, Katie Marie (Author) / Duch, Carsten (Thesis advisor) / Neisewander, Janet (Thesis advisor) / Newfeld, Stuart (Committee member) / Smith, Brian (Committee member) / Orchinik, Miles (Committee member) / Arizona State University (Publisher)
Created2013
Description
The benefits of exercise have been recommended in typical and other special populations. However, the evidence for persons with Down syndrome (DS) is still limited. This study was aimed at investigating the impact of an acute bout of aerobic exercise intervention on motor performance, executive function and intrinsic motivation in adolescents and young adults with DS. Ten participants with DS were assigned to an exercise group, who walked on a incremental treadmill protocol for 20 minutes. The exercise intensity was achieved at 66% of their predicted maximum heart rate. Another ten participants with DS were assigned to an attentional control group, who watched a video for 20 minutes. Measures of fine manual dexterity (e.g., Purdue Pegboard test), manual force production (e.g., grip strength test), processing speed (e.g., visual choice reaction time test), verbal processing (e.g., verbal fluency test), attention shifting ability (e.g., The Dimensional Card sorting test), and inhibitory control (e.g., Knock and Tap test) were tested pre and post intervention. An intrinsic motivation scale (e.g., enjoyment and effort) was conducted after the intervention. First, results showed participants significantly improved their performance in manual force production and Knock and Tap Test after the exercise intervention. While it has been proposed that exercise increases arousal status, neurotransmitters, or cerebral vasculature, the exact mechanisms in persons with DS are still unknown. However, our results showed that after treadmill walking, motor and cognitive improvements can be found in individuals with DS, even in a single exercise session. In addition, participants reported higher scores in enjoyment after video viewing than exercise, which may a result from musical effect or too much emphasis on external rewards in their early participation in exercise. These may imply that participants had low intrinsic motivation to an active lifestyle. Further, scores in effort were significantly higher after exercise than video viewing, which indicated their capabilities to perceive their physical exertion. However, other motivational regulations (e.g., introjected and identified regulations) have shown the relationship with exercise behavior in this population. Thus, further study should consider divergent motivational factors in order to implement an effective exercise program.
ContributorsChen, Chih-Chia (Author) / Ringenbach, Shannon D.R. (Thesis advisor) / Crews, Debra (Committee member) / Kulinna, Pamela (Committee member) / Amazeen, Eric (Committee member) / Arizona State University (Publisher)
Created2013
Description
Although there are many forms of organization on the Web, one of the most prominent ways to organize web content and websites are tags. Tags are keywords or terms that are assigned to a specific piece of content in order to help users understand the common relationships between pieces of content. Tags can either be assigned by an algorithm, the author, or the community. These tags can also be organized into tag clouds, which are visual representations of the structure and organization contained implicitly within these tags. Importantly, little is known on how we use these different tagging structures to understand the content and structure of a given site. This project examines 2 different characteristics of tagging structures: font size and spatial orientation. In order to examine how these different characteristics might interact with individual differences in attentional control, a measure of working memory capacity (WMC) was included. The results showed that spatial relationships affect how well users understand the structure of a website. WMC was not shown to have any significant effect; neither was varying the font size. These results should better inform how tags and tag clouds are used on the Web, and also provide an estimation of what properties to include when designing and implementing a tag cloud on a website.
ContributorsBanas, Steven (Author) / Sanchez, Christopher A (Thesis advisor) / Branaghan, Russell (Committee member) / Cooke, Nancy J. (Committee member) / Arizona State University (Publisher)
Created2011
Description
Working memory (WM) and attention deficits have been well documented in individuals with aphasia (IWA) (e.g. Caspari et al., 1998; Erickson et al., 1996; Tseng et al., 1993; Wright et al., 2003). Research into these cognitive domains has spurred a theoretical shift in how aphasia is conceptualized - from a purely linguistic disorder to a cognitive-information processing account. Language deficits experienced by IWA may result from WM impairments or from an inability to allocate cognitive effort to the tasks. However, how language impacts performance on these tasks has not been readily investigated. Further, there is a need for a more direct measure of effort invested to language tasks. Heart rate variability (HRV) is a physiological measure of cognitive workload that has been used to measure effort in neurologically intact participants. Objectives of the study included: (1) determining the feasibility of using HRV as a measure of effort IWA invest into verbal compared with spatial WM tasks, (2) Comparing participants' performance on verbal and spatial WM tasks; and (3) determining the relationship among performance, perceived task difficulty, and HRV across verbal and spatial tasks. Eleven IWA and 21 age- and education-matched controls completed verbal and spatial n-back tasks at three difficulty levels. Difficulty ratings were obtained before and after each task. Results indicated spatial WM was relatively preserved compared with verbal WM for the aphasia group. Additionally, the aphasia group was better at rating task difficulty after completing the tasks than they were at estimating task difficulty prior to completing the tasks. Significant baseline-task differences in HRV were found for both groups. Relationships between HRV and performance, and HRV and task difficulty were non-significant. Results suggest WM performance deficits in aphasia may be primarily driven by their language deficit. Baseline-task differences in HRV indicate effort is being allocated to the tasks. Difficulty ratings indicate IWA may underestimate task demands for both verbal and spatial stimuli. However, the extent to which difficulty ratings reflect effort allocated remains unclear. Additional research is necessary to further quantify the amount of effort IWA allocate to verbal and non-verbal tasks.
ContributorsChristensen, Stephanie Cotton (Author) / Wright, Heather H. (Thesis advisor) / Ross, Katherine B. (Committee member) / Allen, John J. B. (Committee member) / Katz, Richard C. (Committee member) / Arizona State University (Publisher)
Created2012
Description
There have been conflicting accounts of animation's facilitation in learning from instructional media, being at best no different if not hindering performance. Procedural motor learning represents one of the few the areas in which animations have shown to be facilitative. These studies examine the effects of instructional media (animation vs. static), rotation (facing vs. over the shoulder) and spatial abilities (low vs. high spatial abilities) on two procedural motor tasks, knot tying and endoscope reprocessing. Results indicate that for all conditions observed in which participants engaged in procedural motor learning tasks, performance was significantly improved with animations over static images. Further, performance was greater for rotations of instructional media that did not require participants to perform a mental rotation under some circumstances. Interactions between Media x Rotation suggest that media that was animated and did not require a participant to mentally rotate led to improved performance. Individual spatial abilities were found to influence total steps correct and total number of errors made in the knot tying task, but this was not observed in the endoscope task. These findings have implications for the design of instructional media for procedural motor tasks and provide strong support for the usage of animations in this context.
ContributorsGarland, T. B (Author) / Sanchez, Chris A (Thesis advisor) / Cooke, Nancy J. (Committee member) / Branaghan, Russel (Committee member) / Arizona State University (Publisher)
Created2012
Description
Individual differences in working memory capacity partly arise from variability in attention control, a process influenced by negative emotional content. Thus, individual differences in working memory capacity should be predictive of differences in the ability to regulate attention in emotional contexts. To address this hypothesis, a complex-span working memory task (symmetry span) was modified so that negative arousing images or neutral images subtended the background during the encoding phase. Across three experiments, negative arousing images impaired working memory encoding relative to neutral images, resulting in impoverished symmetry span scores. Additionally, in Experiment 3, both negative and arousing images captured attention and led to increased hit rates in a subsequent recognition task. Contrary to the primary hypothesis, individual differences in working memory capacity derived from three complex span tasks failed to moderate the effect of negative arousing images on working memory encoding across two large scale studies. Implications for theories of working memory and attention control in emotional contexts will be discussed.
ContributorsWingert, Kimberly Marie (Author) / Brewer, Gene A. (Thesis advisor) / Amazeen, Eric (Committee member) / Killeen, Peter (Committee member) / Goldinger, Stephen (Committee member) / Arizona State University (Publisher)
Created2015
Description
Military veterans have a significantly higher incidence of mild traumatic brain injury (mTBI), depression, and Post-traumatic stress disorder (PTSD) compared to civilians. Military veterans also represent a rapidly growing subgroup of college students, due in part to the robust and financially incentivizing educational benefits under the Post-9/11 GI Bill. The overlapping cognitively impacting symptoms of service-related conditions combined with the underreporting of mTBI and psychiatric-related conditions, make accurate assessment of cognitive performance in military veterans challenging. Recent research findings provide conflicting information on cognitive performance patterns in military veterans. The purpose of this study was to determine whether service-related conditions and self-assessments predict performance on complex working memory and executive function tasks for military veteran college students. Sixty-one military veteran college students attending classes at Arizona State University campuses completed clinical neuropsychological tasks and experimental working memory and executive function tasks. The results revealed that a history of mTBI significantly predicted poorer performance in the areas of verbal working memory and decision-making. Depression significantly predicted poorer performance in executive function related to serial updating. In contrast, the commonly used clinical neuropsychological tasks were not sensitive service-related conditions including mTBI, PTSD, and depression. The differing performance patterns observed between the clinical tasks and the more complex experimental tasks support that researchers and clinicians should use tests that sufficiently tax verbal working memory and executive function when evaluating the subtle, higher-order cognitive deficits associated with mTBI and depression.
ContributorsGallagher, Karen Louise (Author) / Azuma, Tamiko (Thesis advisor) / Liss, Julie (Committee member) / Lavoie, Michael (Committee member) / Arizona State University (Publisher)
Created2017
Description
Social gaze-following consists of both reflexive and volitional control mechanisms of saccades, similar to those evaluated in the antisaccade task. This similarity makes gaze-following an ideal medium for studying attention in a social context. The present study seeks to utilize reflexive gaze-following to develop a social paradigm for measuring attention control. Two gaze-following variations of the antisaccade task are evaluated. In version one, participants are cued with still images of a social partner looking either left or right. In version two, participants are cued with videos of a social partner shifting their gaze to the left or right. As with the traditional antisaccade task, participants are required to look in the opposite direction of the target stimuli (i.e., gaze cues). Performance on the new gaze-following antisaccade tasks is compared to the traditional antisaccade task as well as the highly related ability of working memory.
ContributorsYonehiro, Jade Noelani Lee (Author) / Duran, Nicholas D (Thesis advisor) / Burleson, Mary H (Committee member) / Horne, Zachary (Committee member) / Arizona State University (Publisher)
Created2018
Description
Previous research has found improvements in motor and cognitive measures following Assisted Cycle Therapy (AC) in adolescence with Down syndrome (DS). Our study investigated whether we would find improvements in mental health in older adults with DS as measured from the Adapted Behavior Dementia Questionnaire (ABDQ), Physical Activity Self Efficacy Scales (PACES), Children's Depressive inventory, which are early indicators of Alzheimer's disease (AD) in persons with Down syndrome. This study consisted of seven participants with Down syndrome between the ages of 31 and 54, inclusive, that cycled for 30 minutes 3 x/week for eight weeks either at their voluntary cycling rate (VC) or approximately 35% faster with the help of a mechanical motor (ACT). Our results were consistent with our prediction that self efficacy improved following ACT, but not VC. However, our results were not consistent with our prediction that dementia and depression were improved following ACT more than VC. These results were interpreted with respect to the effects of exercise in older adults with DS. Future research should focus on recruiting more participants, especially those with deficits in mental health.
ContributorsPandya, Sachin (Author) / Ringenbach, Shannon (Thesis director) / Coon, David (Committee member) / School of Nutrition and Health Promotion (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05