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As life expectancy continually rises, many age-related conditions such as deteriorated gait and decreased stability begin to play a larger role in affecting the quality of life for all individuals. Medical expenses associated with falls in the elderly population surpassed $50 Billion in 2015 alone. Understanding fall risk and developing

As life expectancy continually rises, many age-related conditions such as deteriorated gait and decreased stability begin to play a larger role in affecting the quality of life for all individuals. Medical expenses associated with falls in the elderly population surpassed $50 Billion in 2015 alone. Understanding fall risk and developing robust metrics and methods of assessment has become more important than ever. While traditional fall risk has looked at classical gait parameters, dynamic stability has gained traction as a more accurate representation of stability during active movement and daily activities. This project seeks to determine the effects on the internal perturbation of gait velocity on dynamic stability represented by the Maximal Lyapunov Exponent (MLE) of multiple acceleration vectors, as well as the efficacy of varying methodology used to assess dynamic stability. Data from 15 healthy, college aged individuals was collected. Significant differences were shown between certain gait velocity trials for one analysis of the three methods explored, while overall trends suggested potential differences between gait velocities with other methodologies warranting further investigation.
ContributorsKreisler, Itai Goeta (Author) / Lockhart, Thurmon (Thesis director) / Rezvanian, Saba (Committee member) / W.P. Carey School of Business (Contributor) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Description
Gait training therapies are methods for improving the walking stability of individuals who have difficulty walking, whether it is due to injury or neuromuscular conditions. Perturbation training that causes individuals to correct their balance and actively improve their stability could potentially lead to longer term benefits for those with unstable

Gait training therapies are methods for improving the walking stability of individuals who have difficulty walking, whether it is due to injury or neuromuscular conditions. Perturbation training that causes individuals to correct their balance and actively improve their stability could potentially lead to longer term benefits for those with unstable gait. Subjects had the medial lateral movement of their center of mass measured through motion-tracking software (D-Flow 3 and Vicon Nexus 2.2). Perturbation training completed with the GRAIL treadmill randomly triggered medial-lateral sway perturbations of 3 cm a total of fifteen times throughout a five minute training period. Data collected to compare baseline, post-training, and one week follow-up dynamic stabilities were recorded over three minutes without any perturbations. There were no statistically significant differences when comparing the results of all subjects at each instance of data collection with each other. Thus, the perturbation training had no significant impact on the dynamic stability of gait. Major limitations that lend to the inconclusive nature of this study include a small sample size, no repetitions, and only one round of training. Further work can be done to better assess the potential impacts of perturbation training on walking stability for therapeutic use.
ContributorsJamali, Neema (Author) / Lockhart, Thurmon (Thesis director) / Soangra, Rahul (Committee member) / School of Biological and Health Systems Engineering (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
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Description
Human walking is a complex and rhythmical activity that comprises of the brain, nerves and muscles. Neuromuscular disorder (NMD) is a broad term that refers to conditions that affect the proper use of muscles and nervous system, thus also impairing the walking or gait cycle of an individual. The improper

Human walking is a complex and rhythmical activity that comprises of the brain, nerves and muscles. Neuromuscular disorder (NMD) is a broad term that refers to conditions that affect the proper use of muscles and nervous system, thus also impairing the walking or gait cycle of an individual. The improper gait cycle might be attributed to the lack of force produced at the toe-off stage. This project addresses if it is possible to create an OpenSim model to find the ideal time and force magnitude needed of an assistive force ankle device to improve gait patterns in individuals with NMD.
ContributorsRivera, Jose Luis (Author) / Zhang, Wenlong (Thesis director) / Lockhart, Thurmon (Committee member) / Harrington Bioengineering Program (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2019-05