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Females are highly vulnerable to the effects of methamphetamine, and understanding the mechanisms of this is critical to addressing methamphetamine use as a public health issue. Hormones may play a role in methamphetamine sensitivity; thus, the fluctuation of various endogenous peptides during the postpartum experience is of interest. This honors

Females are highly vulnerable to the effects of methamphetamine, and understanding the mechanisms of this is critical to addressing methamphetamine use as a public health issue. Hormones may play a role in methamphetamine sensitivity; thus, the fluctuation of various endogenous peptides during the postpartum experience is of interest. This honors thesis project explored the relation between anxiety-like behavior, as measured by activity in an open field, and conditioned place preference to methamphetamine in female versus male rats. The behavior of postpartum as well as virgin female rats was compared to that of male rats. There was not a significant difference between males and females in conditioned place preference to methamphetamine, yet females showed higher locomotor activity in response to the drug as well as increased anxiety-like behavior in open field testing as compared to males. Further study is vital to comprehending the complex mechanisms of sex differences in methamphetamine addiction.
ContributorsBaker, Allison Nicole (Author) / Olive, M. Foster (Thesis director) / Presson, Clark (Committee member) / Hansen, Whitney (Committee member) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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The author examined the relationship between social intelligence and attachment style, specifically how attachment style affects how individuals respond to social intelligence training. Students at the Herberger Young Scholars Academy, a school for the highly gifted, completed an online social intelligence training program through the Social Intelligence Institute and were

The author examined the relationship between social intelligence and attachment style, specifically how attachment style affects how individuals respond to social intelligence training. Students at the Herberger Young Scholars Academy, a school for the highly gifted, completed an online social intelligence training program through the Social Intelligence Institute and were assessed on a number of items. These items include the Tromso Social Intelligence Scale (TSIS), the Attachment Questionnaire for Children (AQ-C), and a daily diary measure in which they recorded and rated their social interactions day to day. All participants were found to be either securely or insecurely attached, and those that were insecurely attached were further divided into insecure anxious attachment style and insecure avoidant attachment style. It was hypothesized that those with a secure attachment style would have higher initial TSIS scores than those with an insecure attachment style. It was also hypothesized that insecurely attached individuals would benefit more from the social intelligence training program than securely attached individuals indicated by "In tune" scores from the daily diaries, and insecure avoidant individuals would benefit more from the program than insecure anxious individuals indicated by "In tune" scores from the daily diaries. None of these hypotheses were supported by the data, as there was no significant difference between the initial social intelligence scores of the three attachment styles, and none of the variables measured were found to be significant predictors of "In tune" scores. Key Words: social intelligence, social intelligence training, attachment, attachment style, children, adolescents, gifted, IQ, high IQ
ContributorsPrice, Christina Nicole (Author) / Zautra, Alex (Thesis director) / Knight, George (Committee member) / Mickelson, Kristin (Committee member) / Barrett, The Honors College (Contributor) / T. Denny Sanford School of Social and Family Dynamics (Contributor) / Department of Psychology (Contributor)
Created2014-12
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Research indicates that adolescents with low quality relationships with parents are susceptible to risk of depression. There is little known about how other relationships relate to depression. This study examined adolescent's relationship with parents, romantic partners, and best friends as a predictor of depressive symptoms. A primarily Dutch population of

Research indicates that adolescents with low quality relationships with parents are susceptible to risk of depression. There is little known about how other relationships relate to depression. This study examined adolescent's relationship with parents, romantic partners, and best friends as a predictor of depressive symptoms. A primarily Dutch population of 80 adolescent couples in the age group of 13 to 18 years old (M = 15.48 SD: 1.16) completed the Epidemiological Depression Scale, Investment Scale of Rusbult, along with an Emotional Warmth scale at Time one and then a year later (Time two). Depressive symptoms at Time two was negatively related with adolescent's emotional warmth with parents. There is also a positive correlation between depressive symptoms at Time one and Time two. However, no significant data was found for an association between satisfaction with romantic partner or best friend and depressive symptoms at Time two. These findings indicate that the type of relationship formed with parents might contribute to the depression adolescent's face.
ContributorsShaikh, Mohammad Usama (Author) / Fabes, Richard (Thesis director) / Ha, Phuong Thao (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor)
Created2014-05
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Scientists, lawyers, and bioethicists have pondered the impact of scientifically deterministic evidence on a judge or jury when deciding the sentence of a criminal. Though the impact may be one that relieves the amount of personal guilt on the part of the criminal, this evidence may also be the very

Scientists, lawyers, and bioethicists have pondered the impact of scientifically deterministic evidence on a judge or jury when deciding the sentence of a criminal. Though the impact may be one that relieves the amount of personal guilt on the part of the criminal, this evidence may also be the very reason that a judge or jury punishes more strongly, suggesting that this type of evidence may be a double-edged sword. 118 participants were shown three films of fictional sentencing hearings. All three films introduced scientifically deterministic evidence, and participants were asked to recommend a prison sentence. Each hearing portrayed a different criminal with different neurological conditions, a different crime, and a different extent of argumentation during closing arguments about the scientifically deterministic evidence. Though the argumentation from the prosecution and the defense did not affect sentencing, the interaction of type of crime and neurological condition did.
ContributorsMeschkow, Alisha Sadie (Author) / Schweitzer, Nicholas (Thesis director) / Robert, Jason (Committee member) / Patten, K. Jakob (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor)
Created2014-05
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Description
An introduction to neuroscientific thought aimed at an audience that is not educated in biology. Meant to be readable and easily understood by anyone with a high school education. The first section is completed in its entirety, with outlines for the proposed final sections to be completed over the next

An introduction to neuroscientific thought aimed at an audience that is not educated in biology. Meant to be readable and easily understood by anyone with a high school education. The first section is completed in its entirety, with outlines for the proposed final sections to be completed over the next few years.
ContributorsNelson, Nicholas Alan (Author) / Olive, M. Foster (Thesis director) / Brewer, Gene (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor)
Created2014-05
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Description
The purpose of the study was to examine the effectiveness of two modes of exercise on depression in adolescents with Down syndrome (DS). Twelve participants randomly completed one of two exercise interventions. The interventions were: 1) Voluntary Cycling (VC), in which participants cycled at their self-selected pedaling rate 2) Assisted

The purpose of the study was to examine the effectiveness of two modes of exercise on depression in adolescents with Down syndrome (DS). Twelve participants randomly completed one of two exercise interventions. The interventions were: 1) Voluntary Cycling (VC), in which participants cycled at their self-selected pedaling rate 2) Assisted Cycling (AC), in which the participants' voluntary pedaling rates were augmented with a motor to ensure the maintenance of 80 rpms. In each intervention, the participant completed three cycling sessions each week for a total of eight weeks. Depression scores did decrease or improved after both AC and VC, but not significantly. There was a greater mean improvement for participants in the AC group than VC when analyzing total score and t-score. Future research will include a greater sample size and control group to reach significant results as well as try and reveal the mechanisms involved in these mental health improvements found after an acute bout of assisted cycling in adolescents with DS.
ContributorsTeslevich, Jennifer Lynn (Author) / Ringenbach, Shannon (Thesis director) / Kulinna, Pamela (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor) / Department of Psychology (Contributor)
Created2013-12
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Description
There is preclinical evidence that the detrimental cognitive effects of hormone loss can be ameliorated by estrogen therapy (Bimonte, Acosta, & Talboom, 2010), however, one of the primary concerns with current hormone therapies is that they are nonselective, leading to increased risk of breast and endometrial cancers as well as

There is preclinical evidence that the detrimental cognitive effects of hormone loss can be ameliorated by estrogen therapy (Bimonte, Acosta, & Talboom, 2010), however, one of the primary concerns with current hormone therapies is that they are nonselective, leading to increased risk of breast and endometrial cancers as well as heart disease. Thus, in order to achieve a successful and clinically relevant long-term hormone therapy option, it is optimal to find an estrogen therapy regimen that is selective to its target tissue. Recently, phytoestrogens have been found to exert selective, beneficial effects on cognition and brain. For example, genistein and diadzein produce neuroprotective effects in cognitive brain regions (Zhao, Chen, & Diaz Brinton, 2002). The purpose of this study was threefold: 1) to examine the cognitive impact of phytoestrogens in young ovariectomized rats, 2) to replicate the dose effects found in the Luine study (Luine et al., 2006), while controlling for manufacturer differences, and 3) to assess if the rodent diet used in our laboratory has an estrogenic-like cognitive impact.The current findings suggest that, at least for object memory, diets containing varying amounts of phytoestrogens can alter cognition, with diets containing high amounts of phytoestrogens showing potential benefits to this type of memory.
ContributorsWhitton, Elizabeth Nicole (Author) / Bimonte-Nelson, Heather (Thesis director) / Presson, Clark (Committee member) / Baxter, Leslie (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor)
Created2013-05
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Description
Substance abuse disorders affect 15.3 million people worldwide. The field has primarily focused on dopaminergic drugs as treatments for substance use disorders. However, recent work has demonstrated the potential of serotonergic compounds to treat substance abuse. Specifically, the serotonin 1B receptor (5-HT1BR), a Gi-coupled receptor located throughout the mesocorticolimbic dopamine

Substance abuse disorders affect 15.3 million people worldwide. The field has primarily focused on dopaminergic drugs as treatments for substance use disorders. However, recent work has demonstrated the potential of serotonergic compounds to treat substance abuse. Specifically, the serotonin 1B receptor (5-HT1BR), a Gi-coupled receptor located throughout the mesocorticolimbic dopamine system, has been implicated in the incentive motivational and rewarding effects of cocaine. Our research suggests that the stimulation of 5-HT1BRs produces different effects at various time points in the addiction cycle. During maintenance of chronic cocaine administration, 5-HT1BR stimulation has a facilitative effect on the reinforcing properties of cocaine. However 5-HT1BR stimulation exhibits inhibitory effects on reinforcement during prolonged abstinence from cocaine. The aim of this study was to examine the possibility of a switch in the functional role of 5-HT1BRs in the locomotor effects of cocaine at different time points of chronic cocaine administration in mice. We found that the 5-HT1BR agonist CP 94,253 increased locomotor activity in mice tested one day after the last chronic cocaine administration session regardless of whether the chronic treatment was cocaine or saline and regardless of challenge injection (i.e., cocaine or saline). Yet after abstinence, CP 94,253 induced a decrease in locomotor activity in mice challenged with saline and attenuated cocaine-induced locomotion relative to cocaine challenge after vehicle pretreatment. These findings suggest that a switch in the functional role of 5-HT1BR is observed at different stages of the addiction cycle and further suggest that clinical applications of drugs acting on 5-HT1BR should consider these effects.
ContributorsBrunwasser, Samuel Joshua (Author) / Neisewander, Janet (Thesis director) / Pentkowski, Nathan (Committee member) / Der-Ghazarian, Taleen (Committee member) / Barrett, The Honors College (Contributor) / Department of Chemistry and Biochemistry (Contributor) / Department of Psychology (Contributor)
Created2014-05
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Description
With divorce rates rising (Kennedy & Ruggles, 2014), it is important to consider the impact of parental marital status on children and adolescents. In this study, we looked at whether children's relationships with their parents differ based on their parents being married or divorced/separated. We hypothesized that a child's perceived

With divorce rates rising (Kennedy & Ruggles, 2014), it is important to consider the impact of parental marital status on children and adolescents. In this study, we looked at whether children's relationships with their parents differ based on their parents being married or divorced/separated. We hypothesized that a child's perceived relationship with their parents would be significantly influenced by parental marital status, such that those whose parents are divorced will demonstrate a negative relationship with the perception of their parents. Using data collected from the longitudinal New England Study of Suburban Youth (NESSY), we ran correlational analyses as well as an analysis of variance (ANOVA) to determine whether different aspects of attachment (Alienation, Communication, and Trust), measured with the Inventory of Parent and Peer Attachment \u2014 Revised for Children (IPPA-R) were significantly linked to parental marital status (Luthar & Barkin, 2012). Using our sample size of 489 students in the twelfth grade, we divided the groups into children with married parents (414) and children with divorced or separated parents (75). An ANOVA produced a significant difference between children's perceived relationship with their father and parental marital status; the adolescents' perception of the father's Alienation, Communication, and Trust were negatively associated with divorce. However, the child's perceived relationship with their mother was similar across both groups. These results suggest further research is needed to determine the effects of a child's perception of their relationship with their father during development, in particular in situations when parents have divorced before high school graduation.
ContributorsSmith, Paulina A. (Co-author) / Smith, Travis W. (Co-author) / Luthar, Suniya S. (Thesis director) / Ciciolla, Lucia (Committee member) / Curlee, Alexandria (Committee member) / School of Social Transformation (Contributor) / Department of Psychology (Contributor) / College of Letters and Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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Description
The action of running is difficult to measure, but well worth it to receive valuable information about one of our most basic evolutionary functions. In the context of modern day, recreational runners typically listen to music while running, and so the purpose of this experiment is to analyze the influence

The action of running is difficult to measure, but well worth it to receive valuable information about one of our most basic evolutionary functions. In the context of modern day, recreational runners typically listen to music while running, and so the purpose of this experiment is to analyze the influence of music on running from a more dynamical approach. The first experiment was a running task involving running without a metronome and running with one while setting one's own preferred running tempo. The second experiment sought to manipulate the participant's preferred running tempo by having them listen to the metronome set at their preferred tempo, 20% above their preferred tempo, or 20% below. The purpose of this study is to analyze whether or not rhythmic perturbations different to one's preferred running tempo would interfere with one's preferred running tempo and cause a change in the variability of one's running patterns as well as a change in one's running performance along the measures of step rate, stride length, and stride pace. The evidence suggests that participants naturally entrained to the metronome tempo which influenced them to run faster or slower as a function of metronome tempo. However, this change was also accompanied by a shift in the variability of one's step rate and stride length.
ContributorsZavala, Andrew Geovanni (Author) / Amazeen, Eric (Thesis director) / Amazeen, Polemnia (Committee member) / Vedeler, Dankert (Committee member) / Department of Psychology (Contributor) / W. P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05