Matching Items (537)

Filtering by

Clear all filters

131351-Thumbnail Image.png

Crew Balance in Construction Tasks for Productivity Analysis - A Sustainability Perspective

Description

The following report followed three separate construction crews at a construction site at ASU and performed labor productivity analysis to quantitatively measure the efficiency of the workers performing specific tasks. These crews were tasked with electrical wiring, concrete pouring, and

The following report followed three separate construction crews at a construction site at ASU and performed labor productivity analysis to quantitatively measure the efficiency of the workers performing specific tasks. These crews were tasked with electrical wiring, concrete pouring, and drywall sanding. Crew balance measured the down time of individual crew members compared to the overall time spent on a task, and the results of these observations were calculated, and suggested improvements given.

Contributors

Agent

Created

Date Created
2020-05

133728-Thumbnail Image.png

Comparing Loading Provisions Between ASCE 7-10 and ASCE 7-16

Description

The loading provisions were compared between the ASCE 7-10 standard and ASCE 7-16 standard. Two different structural models were considered: an office building with a flat roof located in Tempe and a community center with a gable roof located in

The loading provisions were compared between the ASCE 7-10 standard and ASCE 7-16 standard. Two different structural models were considered: an office building with a flat roof located in Tempe and a community center with a gable roof located in Flagstaff. The following load types were considered: dead, live, wind, and snow loads. The only major changes between the standards were found in the wind load calculations. The winds loads were reduced by approximately 22% for the office building in Tempe and 37% for the community center in Flagstaff. A structural design was completed for the frame of the Flagstaff community building. There was a 19% reduction in cost from the design using ASCE 7-10 provisions compared to the design utilizing ASCE 7-16 provisions, leading to a saving of $7,599.17. The reduction in loading, and subsequently more cost-effective design, is attributed to the reduction in basic wind speed for the region and consideration of the ground elevation factor. The introduction of the new ASCE 7-16 standard was met with criticism, especially over the increase in specific coefficients in the wind load and seismic load chapters. Proponents of ASCE 7-16 boast that the new chapter on tsunami loads, new maps for various environmental loads, and a new electronic hazard are some of the merits of the newest standard. Others still question whether the complexity of the provisions is necessary and call for further improvements for the wind and seismic provisions. While tension exists in the desire for a simple standard, ASCE 7-16 prioritizes in having its provisions provide economical and reliable results. More consideration could be devoted to developing a more convenient standard for users. Regardless, engineering professionals should be able to adapt alongside newly developed practices and newly discovered data.

Contributors

Created

Date Created
2018-05

133847-Thumbnail Image.png

Structure-function study of N-isopropylacrylamide copolymers with enzyme degradable GAPGLF and GAPGLL side chains

Description

With an increased demand for more enzyme-sensitive, bioresorbable and more biodegradable polymers, various studies of copolymers have been developed. Polymers are widely used in various applications of biomedical engineering such as in tissue engineering, drug delivery and wound healing. Depending

With an increased demand for more enzyme-sensitive, bioresorbable and more biodegradable polymers, various studies of copolymers have been developed. Polymers are widely used in various applications of biomedical engineering such as in tissue engineering, drug delivery and wound healing. Depending on the conditions in which polymers are used, they are modified to accommodate a specific need. For instance, polymers used in drug delivery are more efficient if they are biodegradable. This ensures that the delivery system does not remain in the body after releasing the drug. It is therefore crucial that the polymer used in the drug system possess biodegradable properties. Such modification can be done in different ways including the use of peptides to make copolymers that will degrade in the presence of enzymes. In this work, we studied the effect of a polypeptide GAPGLL on the polymer NIPAAm and compare with the previously studied Poly(NIPAAm-co-GAPGLF). Both copolymers Poly(NIPAAm-co-GAPGLL) were first synthesized from Poly(NIPAAm-co-NASI) through nucleophilic substitution by the two peptides. The synthesis of these copolymers was confirmed by 1H NMR spectra and through cloud point measurement, the corresponding LCST was determined. Both copolymers were degraded by collagenase enzyme at 25 ° C and their 1H NMR spectra confirmed this process. Both copolymers were cleaved by collagenase, leading to an increase in solubility which yielded a higher LCST compared to before enzyme degradation. Future studies will focus on evaluating other peptides and also using other techniques such as Differential Scanning Microcalorimetry (DSC) to better observe the LCST behavior. Moreover, enzyme kinetics studies is also crucial to evaluate how fast the enzyme degrades each of the copolymers.

Contributors

Agent

Created

Date Created
2018-05

133469-Thumbnail Image.png

Dynamic Changes in Heart Rate and Cerebral Blood Flow During Acute Vagal Nerve Stimulation

Description

Vagal Nerve Stimulation (VNS) has been shown to be a promising therapeutic technique in treating many neurological diseases, including epilepsy, stroke, traumatic brain injury, and migraine headache. The mechanisms by which VNS acts, however, are not fully understood but may

Vagal Nerve Stimulation (VNS) has been shown to be a promising therapeutic technique in treating many neurological diseases, including epilepsy, stroke, traumatic brain injury, and migraine headache. The mechanisms by which VNS acts, however, are not fully understood but may involve changes in cerebral blood flow. The vagus nerve plays a significant role in the regulation of heart rate and cerebral blood flow that are altered during VNS. Here, we examined the effects of acute vagal nerve stimulation on both heart rate and cerebral blood flow. Laser Speckle Contrast Analysis (LASCA) was used to analyze the cerebral blood flow of male Long\u2014Evans rats. Results showed two distinct patterns of responses whereby animals either experienced a mild or severe decrease in heart rate during VNS. Further, animals that displayed mild heart rate decreases showed an increase in cerebral blood flow that persisted beyond VNS. Animals that displayed severe decreases showed a transient decrease in cerebral blood flow followed by an increase that was greater than that observed in mild animals but progressively decreased after VNS. The results suggest two distinct patterns of changes in both heart rate and cerebral blood flow that may be related to the intensity of VNS.

Contributors

Agent

Created

Date Created
2018-05

133517-Thumbnail Image.png

Image Analysis for Registration, Segmentation, and Intensity Measurement of 2-Photon Microscope Images using MATLAB

Description

Traumatic brain injury (TBI) is a major concern in public health due to its prevalence and effect. Every year, about 1.7 million TBIs are reported [7]. According to the According to the Centers for Disease Control and Prevention (CDC), 5.5%

Traumatic brain injury (TBI) is a major concern in public health due to its prevalence and effect. Every year, about 1.7 million TBIs are reported [7]. According to the According to the Centers for Disease Control and Prevention (CDC), 5.5% of all emergency department visits, hospitalizations, and deaths from 2002 to 2006 are due to TBI [8]. The brain's natural defense, the Blood Brain Barrier (BBB), prevents the entry of most substances into the brain through the blood stream, including medicines administered to treat TBI [11]. TBI may cause the breakdown of the BBB, and may result in increased permeability, providing an opportunity for NPs to enter the brain [3,4]. Dr. Stabenfeldt's lab has previously established that intravenously injected nanoparticles (NP) will accumulate near the injury site after focal brain injury [4]. The current project focuses on confirmation of the accumulation or extravasation of NPs after brain injury using 2-photon microscopy. Specifically, the project used controlled cortical impact injury induced mice models that were intravenously injected with 40nm NPs post-injury. The MATLAB code seeks to analyze the brain images through registration, segmentation, and intensity measurement and evaluate if fluorescent NPs will accumulate in the extravascular tissue of injured mice models. The code was developed with 2D bicubic interpolation, subpixel image registration, drawn dimension segmentation and fixed dimension segmentation, and dynamic image analysis. A statistical difference was found between the extravascular tissue of injured and uninjured mouse models. This statistical difference proves that the NPs do extravasate through the permeable cranial blood vessels in injured cranial tissue.

Contributors

Agent

Created

Date Created
2018-05

133535-Thumbnail Image.png

Optical Feedback Mechanism for Detecting Cerebrospinal Fluid Leaks During Spinal Surgery

Description

For my honors thesis, I developed a proof of concept alpha prototype of a biomedical device for detection of cerebrospinal fluid leaks during spinal surgery. Cerebrospinal fluid leaks are a consequence of tears in the dura mater of the spinal

For my honors thesis, I developed a proof of concept alpha prototype of a biomedical device for detection of cerebrospinal fluid leaks during spinal surgery. Cerebrospinal fluid leaks are a consequence of tears in the dura mater of the spinal cord and can result in potentially life-threatening conditions and are overall a large burden not only on the patient but upon the clinical teams managing the patient postoperatively. What I created was an optical sensor that I programmed to be sensitive to detecting green wavelength light. The device would ideally be attached to surgical drain tubing and used in conjunction with fluorescein (a green fluorescent dye) infused lumbar punctures into the spinal canal of patients. As the dye circulates through the spinal cord, any tears in the dura mater would cause the fluorescein to leak out with cerebrospinal fluid into the incision site. This fluid may then be collected by the surgical drain where the sensor may detect the fluorescein, triggering a buzzer response that would notify the patient or the surgeons of an ongoing leak that requires repair. The time I spent on my thesis involved sensor validation to ensure it could differentiate between colors, testing the sensor's color sensitivity by performing a fluorescein aliquot, and running proof of concept testing that could show the sensor can detect fluorescein drain tubing and provide an adequate response. The sensor was able to differentiate between varying concentrations of fluorescein in solution and provided exceptional results in its proof-of-concept testing. Next steps will be to re-run the sensor validation study with different dyes as well as consolidating the device's electrical hardware onto a single circuit board as development of beta and gamma prototypes move forward.

Contributors

Agent

Created

Date Created
2018-05

134402-Thumbnail Image.png

Development of a Mechanical Seismic Simulation Apparatus for College Engineering Education

Description

The School of Sustainable Engineering and the Built Environment (SSEBE) used to have a shake table where FSE 100 professors would use students' model structures to demonstrate how failure occurs during an earthquake. The SSEBE has wanted to build a

The School of Sustainable Engineering and the Built Environment (SSEBE) used to have a shake table where FSE 100 professors would use students' model structures to demonstrate how failure occurs during an earthquake. The SSEBE has wanted to build a shake table ever since the original table was no longer available to them. My creative project is to design and build a shake table for FSE 100 use. This paper will go through the steps I took to design and construct my shake table as well as suggestions to anyone else who would want to build a shake table. The design of the shake table that was constructed was modeled after Quanser's Shake Table II. The pieces from the shake table were purchased from McMaster-Carr and was assembled at the TechShop in Chandler, Arizona. An educational component was added to this project to go along with the shake table. The project will be for the use of a FSE 100 classes. This project is very similar to the American Society of Civil Engineers, Pacific Southwest Conference's seismic competition. The main difference is that FSE 100 students will not be making a thirty story model but only a five story model. This shake table will make Arizona State University's engineering program competitive with other top universities that use and implement shake table analysis in their civil engineering courses.

Contributors

Agent

Created

Date Created
2017-05

134522-Thumbnail Image.png

Customized Endovascular Treatment Fixture Construction for Patient-Specific Cerebral Aneurysm Repair

Description

Cerebral aneurysms are pathological bulges in blood vessels of the brain that can rupture and cause brain damage or death. Treating aneurysms by isolating them from circulation can prevent aneurysm rupture. Endovascular techniques for cerebral aneurysm treatment are preferred because

Cerebral aneurysms are pathological bulges in blood vessels of the brain that can rupture and cause brain damage or death. Treating aneurysms by isolating them from circulation can prevent aneurysm rupture. Endovascular techniques for cerebral aneurysm treatment are preferred because they are minimally invasive and have a shorter recovery time, and endovascular coiling is considered the gold standard as a result. The coils used in endovascular treatment come in standard shapes and sizes, mass-manufactured by medical device companies. Clinicians select the coils for treatment based on the aneurysm volume. However, cerebral aneurysms have unique shapes and dimensions, and vary on a patient-specific basis. Therefore, customizing the coils to fit a unique aneurysm morphology by using shape memory alloys could potentially improve endovascular treatment outcomes. In order to shape set a shape memory alloy into a customized coil configuration a fixture based on the aneurysm morphology must first be developed. Digital surface models of aneurysm patient cases were collected from an online repository and isolated from surrounding vasculature. Anchors used to assist in winding coils around these models were then added to create a computational fixture model. These fixtures were 3D printed in stainless steel, and tested on their ability to maintain their shape after being exposed to high temperatures needed in shape setting processes. The study demonstrated that customized fixtures can be created from patient-specific images or models, and manufactured with high levels of accuracy without deformation at high temperatures. The results suggest that 3D printed stainless steel fixtures could be used to develop customized endovascular coils for cerebral aneurysm treatment.

Contributors

Agent

Created

Date Created
2017-05

134138-Thumbnail Image.png

Earthquake-Induced Soil Liquefaction

Description

This thesis was prepared by Tyler Maynard and Hayley Monroe, who are students at Arizona State University studying to complete their B.S.E.s in Civil Engineering and Construction Engineering, respectively. Both students are members of Barrett, the Honors College, at Arizona

This thesis was prepared by Tyler Maynard and Hayley Monroe, who are students at Arizona State University studying to complete their B.S.E.s in Civil Engineering and Construction Engineering, respectively. Both students are members of Barrett, the Honors College, at Arizona State University, and have prepared the following document for the purpose of completing their undergraduate honors thesis. The early sections of this document comprise a general, introductory overview of earthquakes and liquefaction as a phenomenon resulting from earthquakes. In the latter sections, this document analyzes the relationship between the furthest hypocentral distance to observed liquefaction and the earthquake magnitude published in 2006 by Wang, Wong, Dreger, and Manga. This research was conducted to gain a greater understanding of the factors influencing liquefaction and to compare the existing relationship between the maximum distance for liquefaction and earthquake magnitude to updated earthquake data compiled for the purpose of this report. As part of this research, 38 different earthquake events from the Geotechnical Extreme Events Reconnaissance (GEER) Association with liquefaction data were examined. Information regarding earthquake depth, distance to the furthest liquefaction event (epicentral and hypocentral), and earthquake magnitude (Mw) from recent earthquake events (1989 to 2016) was compared to the previously established relationship of liquefaction occurrence distance to moment magnitude. The purpose of this comparison was to determine if recent events still comply with the established relationship. From this comparison, it was determined that the established relationship still generally holds true for the large magnitude earthquakes (magnitude 7.5 or above) that were considered herein (with only 2.6% falling above the furthest expected liquefaction distance). However, this relationship may be too conservative for recent, low magnitude earthquake events; those events examined below magnitude 6.3 did not approach established range of furthest expected liquefaction distance. The overestimation of furthest hypocentral distance to liquefaction at low magnitudes suggest the empirical relationship may need to be adjusted to more accurately capture recent events, as reported by GEER.

Contributors

Agent

Created

Date Created
2017-12

133958-Thumbnail Image.png

Mexico City: Earthquake Dynamics of Structures

Description

The 8.1 magnitude earthquake that struck Mexico City in 1985 left 10,000 people dead, and over 400 buildings collapsed. The extent of the damage left behind by this powerful quake has been extensively studied to make improvements to engineering and

The 8.1 magnitude earthquake that struck Mexico City in 1985 left 10,000 people dead, and over 400 buildings collapsed. The extent of the damage left behind by this powerful quake has been extensively studied to make improvements to engineering and architectural practices in earthquake-prone areas of the world. Thirty-two years later, on the exact anniversary of the devastating earthquake, Mexico City was once again jolted by a 7.1 magnitude earthquake. Although still significant, the 2017 earthquake collapsed only about a tenth of the buildings collapsed by the 1985 Earthquake, and in turn resulted in a lower death toll. Even though these earthquakes struck in the same seismic region, their effects were vastly different. This thesis completes a comparison between the two earthquakes focusing on the structural impacts including background on Mexico City's unique geology, basic concepts necessary to understand the response of structures to earthquake excitation, and structural failure modes observed in both earthquakes. The thesis will also discuss the earthquake's fundamental differences that led to the discrepancy in structural damage and ultimately in lower death tolls. Of those discussed, is the types of buildings that were targeted and collapsed. In 1985, buildings with 6 or more floors had the highest damage category. Resonance frequencies of these buildings were similar to the resonance frequencies of the subsoil, leading to amplified oscillations, and ultimately in failure. The 2017 earthquake did not have as much distance from the epicenter for the high frequency seismic waves to be absorbed. In contrast, the shorter, faster waves that reached the capital affected smaller buildings, and spared most tall buildings.

Contributors

Created

Date Created
2018-05