Matching Items (75)

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Creativity, Illness, and the Arts: An Anthology Edited and Annotated by Gabrielle Georgini

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Illness is one of the most unfortunate experiences that can occur during one's life. It often emerges without warning and when it is least expected. Illness is not only detrimental to the physical and emotional health of the person who

Illness is one of the most unfortunate experiences that can occur during one's life. It often emerges without warning and when it is least expected. Illness is not only detrimental to the physical and emotional health of the person who is directly diagnosed, however. When one person is diagnosed with any kind of illness, many people are affected. Literature and art have always been used as vehicles to express their creators' thoughts and feelings. Those affected by illness sometimes adopt this method, using the art of storytelling to cope with and express their many emotions. Because there are so many affected people when even only one person is diagnosed, there are several different perspectives that are expressed and must be analyzed. This anthology, titled "Creativity, Medicine, and the Arts: An Anthology Edited and Annotated by Gabrielle Georgini," illustrates the correlation between various kinds of illnessesand literature. According to Merriam-Webster, illness is defined as "obsolete, an unhealthy condition of body or mind" (371). To make a patient healthy again, he must receive some kind oftreatment. Unfortunately, in some cases, a patient may not become healthy again even if they do receive treatment. Literature is an art, and art is a form of therapy. Therefore, patients can use literature and art as forms of treatment. Art and literature provide therapies for the mind. They can allow patients to relax and can work as a distraction from their illnesses. Art and literature can also be a form of expression. Those who are affected by illness can describe or depict their thoughts on paper, enabling them to clear their head or inform others about how they are feeling.

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2018-05

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An Evaluation of the Levonorgestrel-Releasing Intrauterine Device and its Impact on Cognitive Function in a Rat Model

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The aim of this study was to determine whether IUD administration, with and without the presence of Levo, and with and without the presence of the ovaries, impacts cognition in a rat model. Rats received either Sham or Ovariectomy (Ovx)

The aim of this study was to determine whether IUD administration, with and without the presence of Levo, and with and without the presence of the ovaries, impacts cognition in a rat model. Rats received either Sham or Ovariectomy (Ovx) surgery (removal of the ovaries), plus either no IUD, a Blank IUD (without Levo), or a Levo-releasing IUD (Levo IUD), enabling us to evaluate the effects of Ovx and the effects of IUD administration on cognition. Two weeks after surgery, all treatment groups were tested on the water radial arm maze, Morris water maze, and visible platform task to evaluate cognition. At sacrifice, upon investigation of the uteri, it was determined that some of the IUDs were no longer present in animals from these groups: Sham\u2014Blank IUD, Ovx\u2014Blank IUD, and Sham\u2014Levo IUD. Results from the remaining three groups showed that compared to Sham animals with no IUDs, Ovx animals with no IUDs had marginally impaired working memory performance, and that Ovx animals with Levo IUDs as compared to Ovx animals with no IUDs had marginally enhanced memory performance, not specific to a particular memory type. Results also showed that Ovx animals with Levo IUDs had qualitatively more cells in their vaginal smears and increased uterine horn weight compared to Ovx animals with no IUDs, suggesting local stimulation of the Levo IUDs to the uterine horns. Overall, these results provide alternative evidence to the hypothesis that the Levo IUD administers Levo in solely a localized manner, and suggests that the possibility for the Levo IUD to affect reproductive cyclicity in ovary-intact animals is not rejected. The potential for the Levo IUD to exert effects on cognition suggests that either the hormone does in fact systemically circulate, or that the Levo IUD administration affects cognition by altering an as yet undetermined hormonal or other feedback between the uterus and the brain.

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2018-12

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Recollections

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As digital cameras have become more popular over the las two decades film cameras have started to fade into obscurity. Film cameras are now common items at thrift stores as people are getting rid of them to buy more modern

As digital cameras have become more popular over the las two decades film cameras have started to fade into obscurity. Film cameras are now common items at thrift stores as people are getting rid of them to buy more modern cameras. Some of these cameras have undeveloped canisters of film in them that their owners forgot about. For my Honors Thesis I plan to make a photo book comprised of photographs from these undeveloped rolls of film I find.
So far, I have found three rolls of film that were able to be developed. Some of the rolls I have found were blank or too damaged to be developed. I will continue to search for more as I do this project. My goal is to have eight to ten complete rolls by the time I begin making my book.
Developing the pictures is always a surprise. They had remained undeveloped for years until I found them. I never know what will be on the roll. I always have so many questions when I see the pictures for the first time after they are developed. I wonder who took the pictures, where/when they were taken, how they ended up in a thrift store and how subjects would feel about the pictures today. I would like to be able to answer all of these questions, but I know it would be difficult to track down the people in the photos.
Even though the photos are of strangers they seem to still have a sense of nostalgia for me. They remind me of my memories from the era they were taken in. This connection is one of the bases I want to use for my presentation of the photos. One idea I have is to sequence these pictures from least clear to most clear, starting with pictures that can barely be comprehended. I think this would accurately represent memories in my own life. Many of my early memories are more blurred and less coherent but the more recent memories are much clearer. Sequencing will be an important tool for conveying my intended message. There are also many other tools I can use in post processing; however, I want to try to keep the photos as original as possible. There are some ways I could explore manipulating the photos without changing their original unedited look. Some ways I could do this are cropping, resizing and narrative. I will continue to explore these tools as I progress through this project.

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2020-05

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Sculpture of Resistance: Symbolic Reparations in Post-Apartheid Art in District Six, Cape Town

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This essay outlines public art in District Six, Cape Town, South Africa and how public art can manifest itself to reconstruct cultural memory, provide a space for healing and processing collective trauma, and produce critical public pedagogy. Public art also

This essay outlines public art in District Six, Cape Town, South Africa and how public art can manifest itself to reconstruct cultural memory, provide a space for healing and processing collective trauma, and produce critical public pedagogy. Public art also has the power to provide symbolic reparations, an approach proposed by the Truth and Reconciliation Committee but one that I believe was not properly or effectively handled by the South African government. In this paper I will cover two specific public art projects and one established museum, all three framed within the context of both institutionalized and individual approaches to public art. Such projects extend to the District Six Museum, the Public Arts Festival of 1997, and the Black Arts Collective visual-media project, ‘Returning the Gaze.’ This paper proposes that the concept of public art should be reconsidered; I argue that its purpose is not to solely beautify urban landscapes, but rather to provide platforms for survivors of abuse to relay their experiences, influence popular discourse, and challenge hegemonic notions of race, identity, and culture.

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2020-05

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The first in its class? The cognitive effects of the contraceptive hormone drospirenone when given with and without an estrogen

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Drospirenone (DRSP) is a novel, pharmacologically unique synthetic progestin with properties more similar to the endogenous progestogen, progesterone, than any other progestin currently on the market. While a significant amount of research has been conducted on the risks associated with

Drospirenone (DRSP) is a novel, pharmacologically unique synthetic progestin with properties more similar to the endogenous progestogen, progesterone, than any other progestin currently on the market. While a significant amount of research has been conducted on the risks associated with DRSP, the impact of DRSP on cognition, especially in reference to learning and memory, is not well understood. However, it is imperative to fully understand the cognitive effects of DRSP, both alone and in combination with EE (as taken in a combined oral contraceptive [COC]), so that women and their physicians can make a fully-informed decision when deciding to take a DRSP-containing COC. Study 1 examined the effects of three doses of DRSP in order to determine the optimal dose for combining with EE, and found that the medium dose of DRSP (30 µg/day) enhanced spatial working memory performance. In Study 2, the medium dose of DRSP from Study 1 was combined with low (0.125 µg/day) and high (0.3 µg/day) doses of EE to examine the effects of DRSP as taken with EE in a COC. The results from Study 2 indicated that when DRSP was combined with a low, but not high, dose of EE, spatial working memory impairments were seen at the highest working memory load. Anxiety-like behavior was evaluated using the OFT, and DRSP was shown to decrease measures of anxiety-like behavior. Additionally, while treatment with a high dose of EE decreased several measures of anxiety-like behavior, a low dose of EE did not, suggestive of a dose response. Taken together, the findings presented from both studies suggest that some of the cognitive effects of the combination of DRSP with EE are different than those of either hormone administered on its own. Further exploration in a preclinical, ovary-intact animal model is a next step to fully understand these effects in the translational context of a contraceptive, given that women taking an EE-DRSP combination are typically ovary-intact.

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2017-05

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Elucidating the Effects of PRAS40 on Learning and Memory

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The mammalian target of rapamycin (mTOR) is integral in regulating cell growth as it maintains a homeostatic balance of proteins by modulating their synthesis and degradation. In the brain, mTOR regulates protein-driven neuroplastic changes that modulate learning and memory. Nevertheless,

The mammalian target of rapamycin (mTOR) is integral in regulating cell growth as it maintains a homeostatic balance of proteins by modulating their synthesis and degradation. In the brain, mTOR regulates protein-driven neuroplastic changes that modulate learning and memory. Nevertheless, upregulation of mTOR can cause detrimental effect in spatial memory and synaptic plasticity. The proline-rich Akt-substrate 40 kDa (PRAS40) is a key negative regulator of mTOR, as it binds mTOR and directly reduces its activity. To investigate the role of PRAS40 on learning and memory, we generated a transgenic mouse model in which we used the tetracycline-off system to regulate the expression of PRAS40 specifically in neurons of the hippocampus. After induction, we found that mice overexpressing PRAS40 performed better than control mice in the Morris Water Maze behavioral test. We further show that the improvement in memory was associated with a decrease in mTOR signaling, an increase in dendritic spines in hippocampal pyramidal neurons, and an increase in the levels of brain-derived neurotrophic factor (BDNF), a neurotrophin necessary for learning and memory. This is the first evidence that shows that increasing PRAS40 in the mouse brain enhances learning and memory deficits.

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2018-05

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Familiar Places: Ghosts of a Memory

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Familiar Places: Ghosts of a Memory is a thesis exhibition, presented in Gallery 100 in Tempe, AZ, accompanied by a written investigation into the function of photography in the home and art. This project is a diaristic photographic record including

Familiar Places: Ghosts of a Memory is a thesis exhibition, presented in Gallery 100 in Tempe, AZ, accompanied by a written investigation into the function of photography in the home and art. This project is a diaristic photographic record including images of myself, my family, my environment, and mementos or objects that embody family history. I am interested in what we hold onto to keep memories and create our "home". I moved frequently growing up so my sense of home became firmly grounded in family, tradition, and the things we kept close, making home a practiced space not a place. This thesis project explores how material culture, including photographs, is used in creating the space of the home. Questions regarding the nature of the photograph as a memory keeping device or memory trigger is investigated to understand their usefulness and accuracy to the memory. A deeper examination of the difference between an artist's photograph of family and home versus the family photograph is discussed and presented by utilizing installations in the exhibition. The photographs can be seen at www.gwendolynanne.com

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2015-12

Life in a Museum: My Past & Present in Prescott, Arizona

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I am double majoring in Film & Media Production and Geography, and whenever I tell anyone that their first reaction is one of polite incredulity. The two disciplines seem so far from each other that there doesn't seem to be

I am double majoring in Film & Media Production and Geography, and whenever I tell anyone that their first reaction is one of polite incredulity. The two disciplines seem so far from each other that there doesn't seem to be any possible way of combining them. With this project, I wanted to incorporate these two very different fields into one meaningful product. Using film as a medium, I explored how impactful a geographical location can truly be on someone. When we think about our pasts, we often focus on the people and events, losing sight of the physical location where these memories take place. Life in a Museum attempts to shine a light on this forgotten aspect of memory. I moved to Prescott, Arizona when I was 11 and moved away when I was 18, living there for only 7 years. Yet as time passes, I am starting to realize how impactful Prescott has been on me. For my Honors Creative Project, I created a video essay in an attempt to "map" my relationship with Prescott and how it has changed over time. Incorporating digital video, Google SketchUp Animations and historical photographs, Life in a Museum acts as collage that attempts to mimic the tangential aspects of memory. The film addresses my upbringing in Prescott, the town's intense pride for its history, and how living there has affected my own perception of time, memory, death and the future. Link to video: https://vimeo.com/126633587

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2015-05

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Transient Perspective: Refractions On a Semester Abroad

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A longing to revisit the people, places, and moments of my past has followed me for years, sometimes affecting me to the extent that the past seems to intrude on my present. In this piece, I wish to turn a

A longing to revisit the people, places, and moments of my past has followed me for years, sometimes affecting me to the extent that the past seems to intrude on my present. In this piece, I wish to turn a critical eye on these feelings of nostalgia and examine how strong emotion can emerge from nothing more than fractured, faded memories. Using footage of moments I had recorded over six months of living in Europe, I seek to sculpt these images from my past into a form that rejects the daze of nostalgia for the fragmented truth of memory. My background is in more traditional narrative filmmaking, and so I was excited to work in this experimental three-screen format, in which I could explore the concept of memory in a manner that felt truer to how I actually experience it. I tested various combinations of imagery in my videos to build the progression of the piece, which I hoped would play out in an associational style that mimicked the process of my own memory. I hope that this will cause people to walk away from the piece thinking about how memory can fuel emotion and even to investigate their own relationship to the past.

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Date Created
2015-05

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Right Then

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A collection of poems concentrating on 15 small moments, tied together to explore the ardor, tensions, and fragility a relationship. Conceptions of language, teeth, domesticated dogs, and a car accident recur throughout the manuscript as a means of navigating this

A collection of poems concentrating on 15 small moments, tied together to explore the ardor, tensions, and fragility a relationship. Conceptions of language, teeth, domesticated dogs, and a car accident recur throughout the manuscript as a means of navigating this narrative and of questioning the role of memory in our lives.

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Date Created
2015-05