Matching Items (4)
Filtering by
Description
Intracranial aneurysms, which form in the blood vessels of the brain, are particularly dangerous because of the importance and fragility of the human brain. When an intracranial aneurysm gets large it poses a significant risk of bursting and causing subarachnoid hemorrhaging (SAH), a possibly fatal condition. One possible treatment involves placing a stent in the vessel to act as a flow diverter. In this study we look at the hemodynamics of two geometries of idealized basilar tip aneurysms, at 2,3, and 4 ml/s pulsatile flow, at three different points in the cardiac cycle. The smaller model had neck and dome diameters of 2.67 mm and 4 mm respectively, while the larger aneurysm had neck and dome diameters of 3 mm and 6 mm respectively. Both diameters and the dome to neck ratio increased in the second model, representing growth over time. Flow was analyzed using stereoscopic particle image velocimetry (PIV) for both geometries in untreated models, as well as after treatment with a high porosity Enterprise stent (Codman and Shurtleff Inc.). Flow in the models was characterized by root mean square velocity in the aneurysm and neck plane, cross neck flow, max aneurysm vorticity, and total aneurysm kinetic energy. It was found that in the smaller aneurysm model (model 1), Enterprise stent treatment reduced all flow parameters substantially. The smallest reduction was in max vorticity, at 42.48%, and the largest in total kinetic energy, at 75.69%. In the larger model (model 2) there was a 52.18% reduction in cross neck flow, but a 167.28% increase in aneurysm vorticity. The other three parameters experienced little change. These results, along with observed velocity vector fields, indicate a noticeable diversion of flow away from the aneurysm in the stent treated model 1. Treatment in model 2 had a small flow diversion effect, but also altered flow in unpredictable ways, in some cases having a detrimental effect on aneurysm hemodynamics. The results of this study indicate that Enterprise stent treatment is only effective in small, relatively undeveloped aneurysm geometries, and waiting until an aneurysm has grown too large can eliminate this treatment option altogether.
ContributorsLindsay, James Bryan (Author) / Frakes, David (Thesis director) / LaBelle, Jeffrey (Committee member) / Nair, Priya (Committee member) / Barrett, The Honors College (Contributor) / School of Humanities, Arts, and Cultural Studies (Contributor)
Created2013-05
Description
Regicide is a full-length fantasy novel whose world and plot are influenced by the Western Zodiac. It is a coming of age story that reflects an individual's changing views as they come to understand society, religion, and the history of the place where they were born. The book blurb is as follows: "When the king of Celestial Kingdom is murdered and the culprit is unknown, Vernalia Novoa is called to help fill the void his death has created. Though ill-equipped to run a kingdom, she shoulders the burdens as one of the last living Pisces capable of fulfilling the immense responsibilities. With the struggle between doing her job, finding a new ruler, and uncovering the truth about what happened to her people, the passed king’s infamous words echo: people are not always what we hope for them to be."
ContributorsMonson, Cera (Author) / LaCroix, Kristin (Thesis director) / Mara, Miriam (Committee member) / Barrett, The Honors College (Contributor) / Computer Science and Engineering Program (Contributor) / School of Humanities, Arts, and Cultural Studies (Contributor)
Created2023-05
DescriptionI wrote and edited a Young Adult Fiction Novel, preparing it for publication.
ContributorsSparks, Makenzie Taylor (Author) / Amparano Garcia, Julie (Thesis director) / Friedrich, Patricia (Committee member) / School of Humanities, Arts, and Cultural Studies (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
An Ocean of Stars is 310-page novel, written over the span of eight months. The story is one of friendship, love, loss, and finding home. It is centered on the idea that a human's deepest desire is to simply know who they are and where they're from. The two main characters, Alannis and Grey, go on an adventure to discover where they are really from--a hidden continent in the South Pacific Ocean--and stumble into friendship along the way. The novel is 82,000 words and is in the young adult fantasy fiction genre.
ContributorsAnderson, Katy N (Author) / Amparano-Garcia, Julie (Thesis director) / Friedrich, Patricia (Committee member) / Walter Cronkite School of Journalism & Mass Comm (Contributor, Contributor) / School of Humanities, Arts, and Cultural Studies (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12