Organ, cornea and tissue donation is a widespread public health need that has high rates of public approval, but lower rates of action. In Arizona, an individual can register as an organ donor at 15 years and six months old, and this ever-growing demographic is a hard-to-influence, yet important part of the pool of registered donors. There are many factors that serve to influence or dissuade adolescents from registering, and it is the duty of organ procurement organizations (OPOs) and others involved in the donation process to appeal to this audience. This undergraduate research project explores the overall idea of what makes someone register as an organ, cornea and tissue donor by looking into several factors of the decision-making process, such as social media usage and engagement, hesitation or support surrounding spiritual beliefs, and how personal opinions and beliefs shape views and action toward organ donation. Based on the data collected, the researcher found relationships between the registration status of adolescents and their social media use, spiritual beliefs and personal relationships and opinions.