The scientific research conducted by science, technology, engineering, and mathematics (STEM) institutions is groundbreaking. Everyday, scientists create a deeper understanding of the world around us, and then communicate that understanding through journal papers, articles, and conferences. To strengthen these traditional forms of communication, science communicators can use social media platforms such as Twitter and Facebook to promote themselves and earn digital audience engagement that will grow the impact and success of their research. This thesis synthesizes research on human communication theories, digital user behavior, and science communication practices in order to create the “Science Communicator’s Guide to Social Media Engagement”. This guide empowers science communicators to utilize social media in a way that can increase their digital audience engagement, expand the reach of their research, and ultimately amplify their professional presence in the scientific community.