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Description
Sparsity has become an important modeling tool in areas such as genetics, signal and audio processing, medical image processing, etc. Via the penalization of l-1 norm based regularization, the structured sparse learning algorithms can produce highly accurate models while imposing various predefined structures on the data, such as feature groups

Sparsity has become an important modeling tool in areas such as genetics, signal and audio processing, medical image processing, etc. Via the penalization of l-1 norm based regularization, the structured sparse learning algorithms can produce highly accurate models while imposing various predefined structures on the data, such as feature groups or graphs. In this thesis, I first propose to solve a sparse learning model with a general group structure, where the predefined groups may overlap with each other. Then, I present three real world applications which can benefit from the group structured sparse learning technique. In the first application, I study the Alzheimer's Disease diagnosis problem using multi-modality neuroimaging data. In this dataset, not every subject has all data sources available, exhibiting an unique and challenging block-wise missing pattern. In the second application, I study the automatic annotation and retrieval of fruit-fly gene expression pattern images. Combined with the spatial information, sparse learning techniques can be used to construct effective representation of the expression images. In the third application, I present a new computational approach to annotate developmental stage for Drosophila embryos in the gene expression images. In addition, it provides a stage score that enables one to more finely annotate each embryo so that they are divided into early and late periods of development within standard stage demarcations. Stage scores help us to illuminate global gene activities and changes much better, and more refined stage annotations improve our ability to better interpret results when expression pattern matches are discovered between genes.
ContributorsYuan, Lei (Author) / Ye, Jieping (Thesis advisor) / Wang, Yalin (Committee member) / Xue, Guoliang (Committee member) / Kumar, Sudhir (Committee member) / Arizona State University (Publisher)
Created2013
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Description
We solve the problem of activity verification in the context of sustainability. Activity verification is the process of proving the user assertions pertaining to a certain activity performed by the user. Our motivation lies in incentivizing the user for engaging in sustainable activities like taking public transport or recycling. Such

We solve the problem of activity verification in the context of sustainability. Activity verification is the process of proving the user assertions pertaining to a certain activity performed by the user. Our motivation lies in incentivizing the user for engaging in sustainable activities like taking public transport or recycling. Such incentivization schemes require the system to verify the claim made by the user. The system verifies these claims by analyzing the supporting evidence captured by the user while performing the activity. The proliferation of portable smart-phones in the past few years has provided us with a ubiquitous and relatively cheap platform, having multiple sensors like accelerometer, gyroscope, microphone etc. to capture this evidence data in-situ. In this research, we investigate the supervised and semi-supervised learning techniques for activity verification. Both these techniques make use the data set constructed using the evidence submitted by the user. Supervised learning makes use of annotated evidence data to build a function to predict the class labels of the unlabeled data points. The evidence data captured can be either unimodal or multimodal in nature. We use the accelerometer data as evidence for transportation mode verification and image data as evidence for recycling verification. After training the system, we achieve maximum accuracy of 94% when classifying the transport mode and 81% when detecting recycle activity. In the case of recycle verification, we could improve the classification accuracy by asking the user for more evidence. We present some techniques to ask the user for the next best piece of evidence that maximizes the probability of classification. Using these techniques for detecting recycle activity, the accuracy increases to 93%. The major disadvantage of using supervised models is that it requires extensive annotated training data, which expensive to collect. Due to the limited training data, we look at the graph based inductive semi-supervised learning methods to propagate the labels among the unlabeled samples. In the semi-supervised approach, we represent each instance in the data set as a node in the graph. Since it is a complete graph, edges interconnect these nodes, with each edge having some weight representing the similarity between the points. We propagate the labels in this graph, based on the proximity of the data points to the labeled nodes. We estimate the performance of these algorithms by measuring how close the probability distribution of the data after label propagation is to the probability distribution of the ground truth data. Since labeling has a cost associated with it, in this thesis we propose two algorithms that help us in selecting minimum number of labeled points to propagate the labels accurately. Our proposed algorithm achieves a maximum of 73% increase in performance when compared to the baseline algorithm.
ContributorsDesai, Vaishnav (Author) / Sundaram, Hari (Thesis advisor) / Li, Baoxin (Thesis advisor) / Turaga, Pavan (Committee member) / Arizona State University (Publisher)
Created2013
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Description
Surgery as a profession requires significant training to improve both clinical decision making and psychomotor proficiency. In the medical knowledge domain, tools have been developed, validated, and accepted for evaluation of surgeons' competencies. However, assessment of the psychomotor skills still relies on the Halstedian model of apprenticeship, wherein surgeons are

Surgery as a profession requires significant training to improve both clinical decision making and psychomotor proficiency. In the medical knowledge domain, tools have been developed, validated, and accepted for evaluation of surgeons' competencies. However, assessment of the psychomotor skills still relies on the Halstedian model of apprenticeship, wherein surgeons are observed during residency for judgment of their skills. Although the value of this method of skills assessment cannot be ignored, novel methodologies of objective skills assessment need to be designed, developed, and evaluated that augment the traditional approach. Several sensor-based systems have been developed to measure a user's skill quantitatively, but use of sensors could interfere with skill execution and thus limit the potential for evaluating real-life surgery. However, having a method to judge skills automatically in real-life conditions should be the ultimate goal, since only with such features that a system would be widely adopted. This research proposes a novel video-based approach for observing surgeons' hand and surgical tool movements in minimally invasive surgical training exercises as well as during laparoscopic surgery. Because our system does not require surgeons to wear special sensors, it has the distinct advantage over alternatives of offering skills assessment in both learning and real-life environments. The system automatically detects major skill-measuring features from surgical task videos using a computing system composed of a series of computer vision algorithms and provides on-screen real-time performance feedback for more efficient skill learning. Finally, the machine-learning approach is used to develop an observer-independent composite scoring model through objective and quantitative measurement of surgical skills. To increase effectiveness and usability of the developed system, it is integrated with a cloud-based tool, which automatically assesses surgical videos upload to the cloud.
ContributorsIslam, Gazi (Author) / Li, Baoxin (Thesis advisor) / Liang, Jianming (Thesis advisor) / Dinu, Valentin (Committee member) / Greenes, Robert (Committee member) / Smith, Marshall (Committee member) / Kahol, Kanav (Committee member) / Patel, Vimla L. (Committee member) / Arizona State University (Publisher)
Created2013
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Description
As the size and scope of valuable datasets has exploded across many industries and fields of research in recent years, an increasingly diverse audience has sought out effective tools for their large-scale data analytics needs. Over this period, machine learning researchers have also been very prolific in designing improved algorithms

As the size and scope of valuable datasets has exploded across many industries and fields of research in recent years, an increasingly diverse audience has sought out effective tools for their large-scale data analytics needs. Over this period, machine learning researchers have also been very prolific in designing improved algorithms which are capable of finding the hidden structure within these datasets. As consumers of popular Big Data frameworks have sought to apply and benefit from these improved learning algorithms, the problems encountered with the frameworks have motivated a new generation of Big Data tools to address the shortcomings of the previous generation. One important example of this is the improved performance in the newer tools with the large class of machine learning algorithms which are highly iterative in nature. In this thesis project, I set about to implement a low-rank matrix completion algorithm (as an example of a highly iterative algorithm) within a popular Big Data framework, and to evaluate its performance processing the Netflix Prize dataset. I begin by describing several approaches which I attempted, but which did not perform adequately. These include an implementation of the Singular Value Thresholding (SVT) algorithm within the Apache Mahout framework, which runs on top of the Apache Hadoop MapReduce engine. I then describe an approach which uses the Divide-Factor-Combine (DFC) algorithmic framework to parallelize the state-of-the-art low-rank completion algorithm Orthogoal Rank-One Matrix Pursuit (OR1MP) within the Apache Spark engine. I describe the results of a series of tests running this implementation with the Netflix dataset on clusters of various sizes, with various degrees of parallelism. For these experiments, I utilized the Amazon Elastic Compute Cloud (EC2) web service. In the final analysis, I conclude that the Spark DFC + OR1MP implementation does indeed produce competitive results, in both accuracy and performance. In particular, the Spark implementation performs nearly as well as the MATLAB implementation of OR1MP without any parallelism, and improves performance to a significant degree as the parallelism increases. In addition, the experience demonstrates how Spark's flexible programming model makes it straightforward to implement this parallel and iterative machine learning algorithm.
ContributorsKrouse, Brian (Author) / Ye, Jieping (Thesis advisor) / Liu, Huan (Committee member) / Davulcu, Hasan (Committee member) / Arizona State University (Publisher)
Created2014
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Description
In a healthcare setting, the Sterile Processing Department (SPD) provides ancillary services to the Operating Room (OR), Emergency Room, Labor & Delivery, and off-site clinics. SPD's function is to reprocess reusable surgical instruments and return them to their home departments. The management of surgical instruments and medical devices can impact

In a healthcare setting, the Sterile Processing Department (SPD) provides ancillary services to the Operating Room (OR), Emergency Room, Labor & Delivery, and off-site clinics. SPD's function is to reprocess reusable surgical instruments and return them to their home departments. The management of surgical instruments and medical devices can impact patient safety and hospital revenue. Any time instrumentation or devices are not available or are not fit for use, patient safety and revenue can be negatively impacted. One step of the instrument reprocessing cycle is sterilization. Steam sterilization is the sterilization method used for the majority of surgical instruments and is preferred to immediate use steam sterilization (IUSS) because terminally sterilized items can be stored until needed. IUSS Items must be used promptly and cannot be stored for later use. IUSS is intended for emergency situations and not as regular course of action. Unfortunately, IUSS is used to compensate for inadequate inventory levels, scheduling conflicts, and miscommunications. If IUSS is viewed as an adverse event, then monitoring IUSS incidences can help healthcare organizations meet patient safety goals and financial goals along with aiding in process improvement efforts. This work recommends statistical process control methods to IUSS incidents and illustrates the use of control charts for IUSS occurrences through a case study and analysis of the control charts for data from a health care provider. Furthermore, this work considers the application of data mining methods to IUSS occurrences and presents a representative example of data mining to the IUSS occurrences. This extends the application of statistical process control and data mining in healthcare applications.
ContributorsWeart, Gail (Author) / Runger, George C. (Thesis advisor) / Li, Jing (Committee member) / Shunk, Dan (Committee member) / Arizona State University (Publisher)
Created2014
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Description
Multidimensional data have various representations. Thanks to their simplicity in modeling multidimensional data and the availability of various mathematical tools (such as tensor decompositions) that support multi-aspect analysis of such data, tensors are increasingly being used in many application domains including scientific data management, sensor data management, and social network

Multidimensional data have various representations. Thanks to their simplicity in modeling multidimensional data and the availability of various mathematical tools (such as tensor decompositions) that support multi-aspect analysis of such data, tensors are increasingly being used in many application domains including scientific data management, sensor data management, and social network data analysis. Relational model, on the other hand, enables semantic manipulation of data using relational operators, such as projection, selection, Cartesian-product, and set operators. For many multidimensional data applications, tensor operations as well as relational operations need to be supported throughout the data life cycle. In this thesis, we introduce a tensor-based relational data model (TRM), which enables both tensor- based data analysis and relational manipulations of multidimensional data, and define tensor-relational operations on this model. Then we introduce a tensor-relational data management system, so called, TensorDB. TensorDB is based on TRM, which brings together relational algebraic operations (for data manipulation and integration) and tensor algebraic operations (for data analysis). We develop optimization strategies for tensor-relational operations in both in-memory and in-database TensorDB. The goal of the TRM and TensorDB is to serve as a single environment that supports the entire life cycle of data; that is, data can be manipulated, integrated, processed, and analyzed.
ContributorsKim, Mijung (Author) / Candan, K. Selcuk (Thesis advisor) / Davulcu, Hasan (Committee member) / Sundaram, Hari (Committee member) / Ye, Jieping (Committee member) / Arizona State University (Publisher)
Created2014
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Description
In many fields one needs to build predictive models for a set of related machine learning tasks, such as information retrieval, computer vision and biomedical informatics. Traditionally these tasks are treated independently and the inference is done separately for each task, which ignores important connections among the tasks. Multi-task learning

In many fields one needs to build predictive models for a set of related machine learning tasks, such as information retrieval, computer vision and biomedical informatics. Traditionally these tasks are treated independently and the inference is done separately for each task, which ignores important connections among the tasks. Multi-task learning aims at simultaneously building models for all tasks in order to improve the generalization performance, leveraging inherent relatedness of these tasks. In this thesis, I firstly propose a clustered multi-task learning (CMTL) formulation, which simultaneously learns task models and performs task clustering. I provide theoretical analysis to establish the equivalence between the CMTL formulation and the alternating structure optimization, which learns a shared low-dimensional hypothesis space for different tasks. Then I present two real-world biomedical informatics applications which can benefit from multi-task learning. In the first application, I study the disease progression problem and present multi-task learning formulations for disease progression. In the formulations, the prediction at each point is a regression task and multiple tasks at different time points are learned simultaneously, leveraging the temporal smoothness among the tasks. The proposed formulations have been tested extensively on predicting the progression of the Alzheimer's disease, and experimental results demonstrate the effectiveness of the proposed models. In the second application, I present a novel data-driven framework for densifying the electronic medical records (EMR) to overcome the sparsity problem in predictive modeling using EMR. The densification of each patient is a learning task, and the proposed algorithm simultaneously densify all patients. As such, the densification of one patient leverages useful information from other patients.
ContributorsZhou, Jiayu (Author) / Ye, Jieping (Thesis advisor) / Mittelmann, Hans (Committee member) / Li, Baoxin (Committee member) / Wang, Yalin (Committee member) / Arizona State University (Publisher)
Created2014
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Description
Many learning models have been proposed for various tasks in visual computing. Popular examples include hidden Markov models and support vector machines. Recently, sparse-representation-based learning methods have attracted a lot of attention in the computer vision field, largely because of their impressive performance in many applications. In the literature, many

Many learning models have been proposed for various tasks in visual computing. Popular examples include hidden Markov models and support vector machines. Recently, sparse-representation-based learning methods have attracted a lot of attention in the computer vision field, largely because of their impressive performance in many applications. In the literature, many of such sparse learning methods focus on designing or application of some learning techniques for certain feature space without much explicit consideration on possible interaction between the underlying semantics of the visual data and the employed learning technique. Rich semantic information in most visual data, if properly incorporated into algorithm design, should help achieving improved performance while delivering intuitive interpretation of the algorithmic outcomes. My study addresses the problem of how to explicitly consider the semantic information of the visual data in the sparse learning algorithms. In this work, we identify four problems which are of great importance and broad interest to the community. Specifically, a novel approach is proposed to incorporate label information to learn a dictionary which is not only reconstructive but also discriminative; considering the formation process of face images, a novel image decomposition approach for an ensemble of correlated images is proposed, where a subspace is built from the decomposition and applied to face recognition; based on the observation that, the foreground (or salient) objects are sparse in input domain and the background is sparse in frequency domain, a novel and efficient spatio-temporal saliency detection algorithm is proposed to identify the salient regions in video; and a novel hidden Markov model learning approach is proposed by utilizing a sparse set of pairwise comparisons among the data, which is easier to obtain and more meaningful, consistent than tradition labels, in many scenarios, e.g., evaluating motion skills in surgical simulations. In those four problems, different types of semantic information are modeled and incorporated in designing sparse learning algorithms for the corresponding visual computing tasks. Several real world applications are selected to demonstrate the effectiveness of the proposed methods, including, face recognition, spatio-temporal saliency detection, abnormality detection, spatio-temporal interest point detection, motion analysis and emotion recognition. In those applications, data of different modalities are involved, ranging from audio signal, image to video. Experiments on large scale real world data with comparisons to state-of-art methods confirm the proposed approaches deliver salient advantages, showing adding those semantic information dramatically improve the performances of the general sparse learning methods.
ContributorsZhang, Qiang (Author) / Li, Baoxin (Thesis advisor) / Turaga, Pavan (Committee member) / Wang, Yalin (Committee member) / Ye, Jieping (Committee member) / Arizona State University (Publisher)
Created2014
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Description
Social networking services have emerged as an important platform for large-scale information sharing and communication. With the growing popularity of social media, spamming has become rampant in the platforms. Complex network interactions and evolving content present great challenges for social spammer detection. Different from some existing well-studied platforms, distinct characteristics

Social networking services have emerged as an important platform for large-scale information sharing and communication. With the growing popularity of social media, spamming has become rampant in the platforms. Complex network interactions and evolving content present great challenges for social spammer detection. Different from some existing well-studied platforms, distinct characteristics of newly emerged social media data present new challenges for social spammer detection. First, texts in social media are short and potentially linked with each other via user connections. Second, it is observed that abundant contextual information may play an important role in distinguishing social spammers and normal users. Third, not only the content information but also the social connections in social media evolve very fast. Fourth, it is easy to amass vast quantities of unlabeled data in social media, but would be costly to obtain labels, which are essential for many supervised algorithms. To tackle those challenges raise in social media data, I focused on developing effective and efficient machine learning algorithms for social spammer detection.

I provide a novel and systematic study of social spammer detection in the dissertation. By analyzing the properties of social network and content information, I propose a unified framework for social spammer detection by collectively using the two types of information in social media. Motivated by psychological findings in physical world, I investigate whether sentiment analysis can help spammer detection in online social media. In particular, I conduct an exploratory study to analyze the sentiment differences between spammers and normal users; and present a novel method to incorporate sentiment information into social spammer detection framework. Given the rapidly evolving nature, I propose a novel framework to efficiently reflect the effect of newly emerging social spammers. To tackle the problem of lack of labeling data in social media, I study how to incorporate network information into text content modeling, and design strategies to select the most representative and informative instances from social media for labeling. Motivated by publicly available label information from other media platforms, I propose to make use of knowledge learned from cross-media to help spammer detection on social media.
ContributorsHu, Xia, Ph.D (Author) / Liu, Huan (Thesis advisor) / Kambhampati, Subbarao (Committee member) / Ye, Jieping (Committee member) / Faloutsos, Christos (Committee member) / Arizona State University (Publisher)
Created2015
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Description
Advances in data collection technologies have made it cost-effective to obtain heterogeneous data from multiple data sources. Very often, the data are of very high dimension and feature selection is preferred in order to reduce noise, save computational cost and learn interpretable models. Due to the multi-modality nature of heterogeneous

Advances in data collection technologies have made it cost-effective to obtain heterogeneous data from multiple data sources. Very often, the data are of very high dimension and feature selection is preferred in order to reduce noise, save computational cost and learn interpretable models. Due to the multi-modality nature of heterogeneous data, it is interesting to design efficient machine learning models that are capable of performing variable selection and feature group (data source) selection simultaneously (a.k.a bi-level selection). In this thesis, I carry out research along this direction with a particular focus on designing efficient optimization algorithms. I start with a unified bi-level learning model that contains several existing feature selection models as special cases. Then the proposed model is further extended to tackle the block-wise missing data, one of the major challenges in the diagnosis of Alzheimer's Disease (AD). Moreover, I propose a novel interpretable sparse group feature selection model that greatly facilitates the procedure of parameter tuning and model selection. Last but not least, I show that by solving the sparse group hard thresholding problem directly, the sparse group feature selection model can be further improved in terms of both algorithmic complexity and efficiency. Promising results are demonstrated in the extensive evaluation on multiple real-world data sets.
ContributorsXiang, Shuo (Author) / Ye, Jieping (Thesis advisor) / Mittelmann, Hans D (Committee member) / Davulcu, Hasan (Committee member) / He, Jingrui (Committee member) / Arizona State University (Publisher)
Created2014