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Historically, Supreme Court interpretations of the Constitution of the United States have been significantly important, impacting the lives of every American. This honors thesis seeks to understand the ways in which the Constitution has been interpreted through the lens of political ideology. Using constitutional theory, I explain how the political

Historically, Supreme Court interpretations of the Constitution of the United States have been significantly important, impacting the lives of every American. This honors thesis seeks to understand the ways in which the Constitution has been interpreted through the lens of political ideology. Using constitutional theory, I explain how the political ideologies of classical liberalism, conservatism, libertarianism, and progressive liberalism have played a role in the interpretations of the First, Second, and Fourth Amendments. I also examine how these ideological interpretations have changed from 1776 to 2017, dividing the history of the United States into four eras: the Founding Era, the Civil War Era, the New Deal Era, and the Modern Era. First, the First Amendment's clauses on religion are examined, where I focus on the separation between church and state as well as the concepts of "establishment" and "free exercise." The First Amendment transitions from classically liberal, to conservative, to progressively liberal and classically liberal, to progressively liberal and libertarian. Next, we look at the Second Amendment's notions of a "militia" and the "right to keep and bear arms." The Second Amendment's interpretations begin classically liberal, then change to classically liberal and progressively liberal, to progressively liberal, to conservative. Finally, the analysis on the Fourth Amendment's "unreasonable searches and seizures" as well as "warrants" lends evidence to ideological interpretations. The Fourth Amendment, like the other two, starts classically liberal for two eras, then becomes libertarian, and finally ends libertarian and conservative. The implications of each of these conclusions are then discussed, with emphasis on public opinion in society during the era in question, the ways in which the ideologies in each era seem to build upon one another, the ideologies of the justices who wrote the opinions, and the ideology of the court.
Created2017-12
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Although smaller and more local elections could have implications more dramatic to an individual than larger district-, state-, and nation-wide elections do, very few citizens vote in them. Moreover, citizens are limited in procuring further information on candidates, issues, and the overall election when there are fewer sources of such

Although smaller and more local elections could have implications more dramatic to an individual than larger district-, state-, and nation-wide elections do, very few citizens vote in them. Moreover, citizens are limited in procuring further information on candidates, issues, and the overall election when there are fewer sources of such information across various mediums. While existing literature on political communication and voter participation does not yet extend far enough to sufficiently address the most local aspects of media effects on elections, the political science field’s dominating frameworks would suggest that an increase in news media, social media, and ground mobilization tactics would increase civic engagement and voter participation. My research, which focuses on hyperlocal elections, both supports a​nd​refutes certain elements of that suggestion. Based on surveys of potential voters in a university’s student government election and a school board election, interviews with two student government presidential candidates, and an analysis of social media engagement, my research compares three mass media platforms and two elections to characterize the effects of media on hyperlocal elections—that certain tactics have drastically different results on different populations. My research expands the body of media and politics knowledge to include hyperlocal elections, suggesting that civic engagement on the local levels require increased further study.
Created2015-05
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Bexarotene is a commercially produced drug commonly known as Targetin presecribed to treat cutaneous T-cell lymphoma (CTCL). Bex mimics the actions of natural 9-cis retinoic acid in the body, which are derived from Vitamin A in the diet and boost the immune system. Bex has been shown to be effective

Bexarotene is a commercially produced drug commonly known as Targetin presecribed to treat cutaneous T-cell lymphoma (CTCL). Bex mimics the actions of natural 9-cis retinoic acid in the body, which are derived from Vitamin A in the diet and boost the immune system. Bex has been shown to be effective in the treatment of multiple types of cancer, including lung cancer. However, the disadvantages of using Bex include increased instances of hypothyroidism and excessive concentrations of blood triglycerides. If an analog of Bex can be developed which retains high affinity RXR binding similar to the 9-cis retinoic acid while exhibiting less interference for heterodimerization pathways, it would be of great clinical significance in improving the quality of life for patients with CTCL. This thesis will detail the biological profiling of additional novel (Generation Two) analogs, which are currently in submission for publication, as well as that of Generation Three analogs. The results from these studies reveal that specific alterations in the core structure of the Bex "parent" compound structure can have dramatic effects in modifying the biological activity of RXR agonists.
ContributorsYang, Joanna (Author) / Jurutka, Peter (Thesis director) / Wagner, Carl (Committee member) / Hibler, Elizabeth (Committee member) / Barrett, The Honors College (Contributor)
Created2012-05
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Description
Bexarotene (Targretin®) is an FDA approved drug used to treat cutaneous T-cell lymphoma (CTCL), as well as off-label treatments for various cancers and neurodegenerative diseases. Previous research has indicated that bexarotene has a specific affinity for retinoid X receptors (RXR), which allows bexarotene to act as a ligand-activated-transcription factor

Bexarotene (Targretin®) is an FDA approved drug used to treat cutaneous T-cell lymphoma (CTCL), as well as off-label treatments for various cancers and neurodegenerative diseases. Previous research has indicated that bexarotene has a specific affinity for retinoid X receptors (RXR), which allows bexarotene to act as a ligand-activated-transcription factor and in return control cell differentiation and proliferation. Bexarotene targets RXR homodimerization to drive transcription of tumor suppressing genes; however, adverse reactions occur simultaneously when bound to other nuclear receptors. In this study, we used novel bexarotene analogs throughout 5 iterations synthesized in the laboratory of Dr. Wagner to test for their potency and ability to bind RXR. The aim of our study is to quantitatively measure RXR homodimerization driven by bexarotene analogs using a yeast two-hybrid system. Our results suggests there to be several compounds with higher protein activity than bexarotene, particularly in generations 3.0 and 5.0. This higher affinity for RXR homodimers may help scientists identify a compound that will minimize adverse effects and toxicity of bexarotene and serve as a better cancer treatment alternative.
ContributorsSeto, David Hua (Author) / Marshall, Pamela (Thesis director) / Wagner, Carl (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Natural Sciences (Contributor) / School of Social and Behavioral Sciences (Contributor)
Created2015-05
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Description
We were interested in whether or not certain demographics, such as gender, age, education level, and academic major, would affect an individual's political awareness. In particular, we hypothesized that Political Science majors would have a higher level of political awareness than Non-Political Science majors. In an in-person survey, we asked

We were interested in whether or not certain demographics, such as gender, age, education level, and academic major, would affect an individual's political awareness. In particular, we hypothesized that Political Science majors would have a higher level of political awareness than Non-Political Science majors. In an in-person survey, we asked participants on the Arizona State University, Tempe campus a series of nine questions measuring government structure and procedure, current politics, and policy issues. Our findings concluded that, within our sample: 1) on average, Political Science majors outperformed Non-Political Science majors 2) education level appears to be positively associated with political awareness 3) like education, age appears to be positively associated with political awareness, however, there seemed to be a peak at 21 years of age 4) males outperformed females, as suggested by research studying the gender gap in political knowledge. Because our sample population was not randomly selected, and this report focuses on descriptive statistics, we cannot generalize or comment on our findings' statistical significance. However, many of our findings are supported by current research and, with further specification, may be of interest to university officials who seek to measure the political knowledge and awareness of various demographic groups on campus.
ContributorsTaylor, Kaela (Co-author) / Leung, Emily (Co-author) / Lennon, Tara (Thesis director) / Woodall, Gina (Committee member) / Barrett, The Honors College (Contributor) / W. P. Carey School of Business (Contributor) / School of International Letters and Cultures (Contributor) / School of Politics and Global Studies (Contributor) / Department of Information Systems (Contributor) / School of Accountancy (Contributor)
Created2014-05
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In this work we analyze just what makes the topic of third party voting so intriguing to voters and why it is different than voting for one of the major parties in American politics. First, we will discuss briefly the history of politics in America and what makes it exciting.

In this work we analyze just what makes the topic of third party voting so intriguing to voters and why it is different than voting for one of the major parties in American politics. First, we will discuss briefly the history of politics in America and what makes it exciting. Next, we will outline some of the works by other political and economic professionals such as Hotelling, Lichtman and Rietz. Finally, using the framework described beforehand this paper will analyze the different stances that voters, candidates, and others involved in the political process of voting have regarding the topic of third party voting.
ContributorsMcElroy, Elizabeth (Co-author) / Beardsley, James (Co-author) / Foster, William (Thesis director) / Goegan, Brian (Committee member) / Department of Economics (Contributor) / School of International Letters and Cultures (Contributor) / Economics Program in CLAS (Contributor) / School of Politics and Global Studies (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
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The implementation of gender quotas in the Costa Rican legislature presents an interesting case study that with the use of national legislative gender quotas, women’s issues are more positively addressed within the country. This analysis argues that with the higher presence of women legislators in the Legislative Assembly made possible

The implementation of gender quotas in the Costa Rican legislature presents an interesting case study that with the use of national legislative gender quotas, women’s issues are more positively addressed within the country. This analysis argues that with the higher presence of women legislators in the Legislative Assembly made possible by the quota these women. in turn, have created more gender-focused policies. Thusly, higher amounts of female-focused policy will positively impact women’s issue areas within Costa Rican society. This argument will be supported by other scholar’s research on the subject of the gender quota and female equality in Costa Rica. I will also be presenting my own research that will investigate the data taken from the Costa Rican health ministry, UNICEF, and other organizations to comparatively evaluate the improvement of problems that women face coinciding with the higher female presence in the legislature.
ContributorsBlythe, Alexandra (Author) / Shair-Rosenfield, Sarah (Thesis director) / Funk, Kendall (Committee member) / School of Politics and Global Studies (Contributor, Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
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Following the fall of communism in Romania which took place on December 25, 1989, those living within the country as well as others around the world believed the ushering of a nation towards a brighter future was underway. The limitations imposed by the dictator Nicolae Ceausescu were removed and a

Following the fall of communism in Romania which took place on December 25, 1989, those living within the country as well as others around the world believed the ushering of a nation towards a brighter future was underway. The limitations imposed by the dictator Nicolae Ceausescu were removed and a brighter future was on the horizon. Twenty-seven years have passed since this historical event in Romanian history, yet the country is far removed from that brighter future, as it is now plagued by other symptoms. The transition from communism to a fully functioning democracy has not been as smooth or as quick as many initially expected, and although some problems are no longer prevalent, others are becoming a staple of the nation. The Colectiv nightclub fire exemplifies the current obstacles and drawbacks of present day Romania, which impede the country's further progress to becoming a truly democratic nation, free from corruption and other widespread negative forces. Although the results of the incident which happened on the night of October 30th, 2015 are devastating and painful for those involved, their families, and to the entire country as a whole, the factors which led to this tragedy must be examined and rectified in order to help prevent any such event from reoccurring in the future. Throughout this analysis, I will proceed by first outlining the damaged system within both the Romanian government and society, and then examine how these shortcomings had a direct impact on the disaster which took place on the night of October 30th, 2015.
ContributorsToader, Alin Christian (Author) / Orlich, Ileana (Thesis director) / Paulesc, Julieta (Committee member) / School of Politics and Global Studies (Contributor) / Sandra Day O'Connor College of Law (Contributor) / School of International Letters and Cultures (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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In this undergraduate thesis, I explore the relationship between politics and popular culture through an ethnography of Justice League Arizona, a cosplay ensemble devoted to costumed civic activism. While existing scholarship addresses cosplay ensembles and political theory, there is very little that examines how the act of cosplay can be

In this undergraduate thesis, I explore the relationship between politics and popular culture through an ethnography of Justice League Arizona, a cosplay ensemble devoted to costumed civic activism. While existing scholarship addresses cosplay ensembles and political theory, there is very little that examines how the act of cosplay can be a form of politics and what the impact of that interpretation has on both individuals and the community at large. Through both participant observation and interviews with members of the ensemble, I discovered that cosplay has the ability to intensify aspects of the self, the ability to expose new aspects of the self, and the ability to bring one closer to a particular character. I also found cosplay to be political through the sensibility and situated knowledge that proves to be in practice during cosplay, ultimately having the power to be used as a form of political resistance.
ContributorsBurrus, Ella Rene (Author) / Mack, Robert (Thesis director) / Behl, Natasha (Committee member) / School of Social and Behavioral Sciences (Contributor) / Herberger Institute for Design and the Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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There exists a strong correlation between successful democratic governance and citizen participation. Pulling this sense of civic engagement to the furthest end of the spectrum, author and political theorist Benjamin Barber expresses the benefits of citizen independence and self-governance though political deliberation in a variety of texts, one of which

There exists a strong correlation between successful democratic governance and citizen participation. Pulling this sense of civic engagement to the furthest end of the spectrum, author and political theorist Benjamin Barber expresses the benefits of citizen independence and self-governance though political deliberation in a variety of texts, one of which being Strong Democracy. While the United States currently operates on a "democratic" base, the overall lack of political efficacy undermines democratic effectiveness. Benjamin Barber outlines a series of solutions and employment strategies in order to increase efficacy and bolster civic engagement and bring about a culture of self-legislation, but in his analysis seems to overlook the collaborative capacity of the Internet, more specifically social media outlets and blogs. This study will examine the use of the Internet in various political manners, to observe if the presence of platforms such as social networks and blogs are facilitating or hindering the push towards a more civic-republican political structure. While research has displayed that the numbers on political internet-usage are consistently increasing, it is evident that not all forms of online-engagement are beneficial towards Barber's Civic Republican ideals, and may serve to strengthen the current unsound system. Through this study, I argue that certain methods of political activity over the Internet may work to support the collaborative democratic culture, and increase a sense of Civic Republicanism through political creativity, deliberation and online-action. If we are to one day achieve the goal of recovering a true sense of cooperative democracy, these forms of participation may play a significant role in the struggle for change, and must be facilitated through both civic education and the cooperation of elites. If this Internet-mediated political deliberation continues to develop, I believe that it has the capacity to act as a significant catalyst towards Barber's Civic Republican ideals and an overall shift in the political culture.
ContributorsSalute, Nicholas John (Author) / Kirkpatrick, Jennet (Thesis director) / Halavais, Alex (Committee member) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05