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Human Physiological Adaptations to Starvation and Caloric Restriction

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Throughout history humans have had to adapt to changing conditions in order to survive. Food shortages are one of the major pressures that have shaped past populations. Because of this, the human body has many physiological adaptations that allow

Throughout history humans have had to adapt to changing conditions in order to survive. Food shortages are one of the major pressures that have shaped past populations. Because of this, the human body has many physiological adaptations that allow it to go extended periods of time consuming little to no food. These adaptations also allow the body to recover quickly once food becomes available. They include changes in metabolism that allow different fuel sources to be used for energy, the storing of excess energy absorbed from food in the forms of glycogen and fat to be used in between meals, and a reduction in the basal metabolic rate in response to starvation, as well as physiological changes in the small intestines. Even in places where starvation is not a concern today, these adaptations are still important as they also have an effect on weight gain and dieting in addition to promoting survival when the body is in a starved state.

Disclaimer: The initial goal of this project was to present this information as a podcast episode as a part of a series aimed at teaching the general public about human physiological adaptations. Due to the circumstances with COVID-19 we were unable to meet to make a final recording of the podcast episode. A recording of a practice session recorded earlier in the year has been uploaded instead and is therefore only a rough draft.

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2020-05

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Precarious Fauna: An Art Exhibition

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Human nature drives us to focus primarily on the present or near-future, instead of considering what consequences our actions may have many years from now. However, in a new era that is increasingly dominated by humans and their ambitions, this

Human nature drives us to focus primarily on the present or near-future, instead of considering what consequences our actions may have many years from now. However, in a new era that is increasingly dominated by humans and their ambitions, this tendency has destructive repercussions on the very environment that once supported and nurtured humankind. Wild animals are highly susceptible to human activities that damage ecosystems, and a loss of animal diversity can have unforeseen consequences on future human populations. In the research, I examine the avoidable reasons for the severe decline in population of four animal species, and through my art, imagine the losses associated with their disappearance. The artwork created evokes an emotional response in the viewer through dramatic, contrasting imagery, making them reassess the relationship between humans, animals and the environment.

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2018-05

Tell It to the Frogs: Fukushima’s nuclear disaster and its impact on the Japanese Tree Frog

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“Tell It to the Frogs: Fukushima’s nuclear disaster and its impact on the Japanese Tree Frog” is a representation of the work from Giraudeau et. al’s “Carotenoid distribution in wild Japanese tree frogs (Hyla japonica) exposed to ionizing radiation in

“Tell It to the Frogs: Fukushima’s nuclear disaster and its impact on the Japanese Tree Frog” is a representation of the work from Giraudeau et. al’s “Carotenoid distribution in wild Japanese tree frogs (Hyla japonica) exposed to ionizing radiation in Fukushima.” This paper looked to see if carotenoid levels in the tree frog’s vocal sac, liver, and blood were affected by radiation from Fukushima’s power plant explosion. Without carotenoids, the pigment that gives the frogs their orange color on their necks, their courtship practices would be impacted and would not be as able to show off their fitness to potential mates. The artwork inspired by this research displayed the tree frog’s degradation over time due to radiation, starting with normal life and ending with their death and open on the table. The sculptures also pinpoint where the carotenoids were being measured with a brilliant orange glaze. Through ceramic hand building, the artist created larger than life frogs in hopes to elicit curiosity about them and their plight. While the paper did not conclude any changes in the frog’s physiology after 18 months of exposure, there are still questions that are left unanswered. Why did these frogs not have any reaction? Could there be any effects after more time has passed? Is radiation leakage as big of a problem as previously thought? The only way to get the answers to these questions is to be aware of these amphibians, the circumstances that led them to be involved, and continued research on them and radiation.

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2019-05

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Loose Lace Baby

Description

“Loose Lace Baby” is a multimedia creative project that includes the creation of a song, a music video, and cover art. The project began with the songwriting process, which became the inspiration for the video concept. The final cover art

“Loose Lace Baby” is a multimedia creative project that includes the creation of a song, a music video, and cover art. The project began with the songwriting process, which became the inspiration for the video concept. The final cover art is based on the themes and aesthetics of the song and video combined. This project’s purpose was to explore the creative process across multiple media forms and how those forms can work to inspire and enhance one another. The first stage of the project was the songwriting and recording stage. The song is a simple love song about feeling insecure in a relationship and is centered on the metaphor of “tripping over loose shoelaces”. The process in this stage included creative idea exchange, songwriting, music production, and research in different methods of song creation. This portion of the project was then used to inspire the second stage, which was the music video. The music video is about a young boy’s first major crush and follows him on his journey to tell her how he feels, which ultimately ends poorly for him, but goes to show that love can be a divisive but also binding force. The caveat to this boy’s crush is that it ends up being his babysitter, who is much older than him and therefore does not reciprocate his feeling despite having a meaningful connection of a different nature with him. This portion of the project involved many elements, namely using sound as a source of inspiration for moving visual art, production and design, learning about camera work, directing, scripting, screenplay, acting, editing, and most of all, collaboration. Finally, Once these stages of the project came together, the final stage was to draw on the core ideas of the two to create a piece of cover art that represented the messages from both the song and the music video, cohesively binding the multiple media forms into one final product. This stage involved photography, image editing, and pulling from the two other media forms to create a cohesive representative image The final product is a music video and song that are approximately four minutes long each, and a single cover art image. The main software used for music production was Ableton Live. The camera used was a Sony A6300 and the main video editing software used was Adobe Premiere. Many learning outcomes were reached, including multiple filming and editing techniques, video production and the work that goes into organizing and directing a film project, music production methods such as vocal recording and processing, live instrument recording, song arrangement and the use of a Digital Audio Workstation for production and mixing. An in-depth analysis of the entire process is given in detail in the following pages.

"Loose Lace Baby" music video: https://www.youtube.com/watch?v=K5uPf7Psht8&feature=youtu.be

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2020-05

Functional Art as a Representative Medium

Description

Items that have once served as tools in the past become something of greater value in the future: art. Ceramics is a craft that has gone beyond its simple functions to become a representative medium. This ability makes ceramics an

Items that have once served as tools in the past become something of greater value in the future: art. Ceramics is a craft that has gone beyond its simple functions to become a representative medium. This ability makes ceramics an art. This will be demonstrated by representing enzyme-substrate binding and inhibition through the use of a dinner set.

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2020-05

Integrating Art and Science: Evolution of the Beak

Description

Evolution is a powerful process that acts on features as organisms adapt to fill a variety of niches. It is visible in the emergence of the beak in the fossil record, through a number of small changes over time. To

Evolution is a powerful process that acts on features as organisms adapt to fill a variety of niches. It is visible in the emergence of the beak in the fossil record, through a number of small changes over time. To explain and convey these changes to a general audience, I produced an art book combining my review of bird beak evolution with art. The intent was to present evolution in an informative, visual, and engaging manner that a general audience would be able to understand.

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Date Created
2020-05

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The People Project: Personhood Painted Orange

Description

Perhaps the most compelling thing about any one human being is their story. There are stories that get shouted through media, thus reinforcing their social value. There are also stores that go systematically untold, diminishing or erasing the social value

Perhaps the most compelling thing about any one human being is their story. There are stories that get shouted through media, thus reinforcing their social value. There are also stores that go systematically untold, diminishing or erasing the social value of those they represent. My creative project, The People Project, seeks to give incarcerated writers a platform (albeit small) on which to share and develop their stories (through submissions to Iron City Magazine), and to share my own story of teaching within the prison walls. The People Project is a collection of short essays that seeks to explore the personhood that exists underneath the mandated orange outfits, and ultimately seeks to prompt discussion about the incarceration system as a whole.

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Date Created
2018-05

Dichotomy: A Framework for Curative Drawing to Reduce Stress

Description

Curative arts and art therapy have been increasingly implicated in promoting health and well-being for patients, but little research has been done for the benefits of drawing therapy for stress management or individuals in a non-diseased state. College students and

Curative arts and art therapy have been increasingly implicated in promoting health and well-being for patients, but little research has been done for the benefits of drawing therapy for stress management or individuals in a non-diseased state. College students and healthcare professionals are particularly susceptible to high levels of stress, as I experienced firsthand as a medical scribe in the Emergency Room during my undergraduate experience. For this reason, I wanted to focus on using curative arts as a mediator for high-stress situations. My creative project is therefore a portable framework for curative drawing. The framework is designed to help people process complex emotional states in a more effective way using mark-making and color. Specifically, the framework is designed for those who have limited experience with art making but can be used by anyone who feels a need for curative drawing. I used this framework in both individual and group settings, culminating in a final gallery show in which viewers were able to participate in the framework and take home a booklet with the framework printed inside. In conjunction with outside research, the help of my thesis committee, and the students of Drawing and Painting as Seeing and Thinking, the final project can be viewed as one part of the intersection between art and medicine in our ever-changing healthcare environment.

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Date Created
2018-05

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Characterization of Second and Third Generation, Novel RXR Selction Agonists for the Treatment of Cutaneous T-Cell Lymphoma

Description

Bexarotene is a commercially produced drug commonly known as Targetin presecribed to treat cutaneous T-cell lymphoma (CTCL). Bex mimics the actions of natural 9-cis retinoic acid in the body, which are derived from Vitamin A in the diet and boost

Bexarotene is a commercially produced drug commonly known as Targetin presecribed to treat cutaneous T-cell lymphoma (CTCL). Bex mimics the actions of natural 9-cis retinoic acid in the body, which are derived from Vitamin A in the diet and boost the immune system. Bex has been shown to be effective in the treatment of multiple types of cancer, including lung cancer. However, the disadvantages of using Bex include increased instances of hypothyroidism and excessive concentrations of blood triglycerides. If an analog of Bex can be developed which retains high affinity RXR binding similar to the 9-cis retinoic acid while exhibiting less interference for heterodimerization pathways, it would be of great clinical significance in improving the quality of life for patients with CTCL. This thesis will detail the biological profiling of additional novel (Generation Two) analogs, which are currently in submission for publication, as well as that of Generation Three analogs. The results from these studies reveal that specific alterations in the core structure of the Bex "parent" compound structure can have dramatic effects in modifying the biological activity of RXR agonists.

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2012-05

Internationally Gluten-Free On a Shoestring

Description

Gluten is another name for natural proteins found in wheat, rye, barley and other grains that are commonly found in most boxed, pre-made, or baked items. However, the number of people diagnosed with Celiac's Disease, Non-Celiac Gluten Sensitivity, or Wheat

Gluten is another name for natural proteins found in wheat, rye, barley and other grains that are commonly found in most boxed, pre-made, or baked items. However, the number of people diagnosed with Celiac's Disease, Non-Celiac Gluten Sensitivity, or Wheat Allergy has risen dramatically over the past few decades. In fact, the Gluten-Free Market is estimated to be worth 6.6 billion dollars by 2017. Therefore, this cookbook was made to provide quick, easy, and diverse recipes for people unable to ingest gluten without hurting their wallets.

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2016-05