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Health and Wealthness is a podcast where your hosts, Emily Weigel and Hanaa Khan discuss pressing and trending topics about health and wealth that everyone should know about. Our first four episodes focus on the opioid crisis. Both the science and healthcare sides. We then go on to talk about burnout and mental health in a conversational episode.
Our current understanding of the mitochondrial genome was revolutionized in 2015 with the discovery of short open reading frames (sORFs) that produced protein products called mitochondrial-derived peptides (MDPs). Interestingly, unlike other proteins produced by the organelle, these MDPs are not directly involved in the electron transport chain but rather serve the role of metabolic regulators. In particular, one of these peptides called MOTS-c has been shown to regulate glucose and fat metabolism in an AMPK-dependent manner. With its capacity to enter the mitochondria and impact gene expression, MOTS-c has also displayed the ability to increase aerobic exercise performance by triggering elevated synthesis of the HO-1 antioxidant. Overall these findings position MOTS-c as a promising treatment for metabolic diseases as well as a potential dietary supplement to boost ATP availability.
Disclaimer: The initial goal of this project was to present this information as a podcast episode as a part of a series aimed at teaching the general public about human physiological adaptations. Due to the circumstances with COVID-19 we were unable to meet to make a final recording of the podcast episode. A recording of a practice session recorded earlier in the year has been uploaded instead and is therefore only a rough draft.
Disclaimer: Due to the COVID-19 global pandemic, the final outcomes of this project were impacted and limited. Therefore, the rough draft practice podcast session has been uploaded to accompany the written thesis portion as final recordings could not be recorded at this time.
The integrative model for developmental competencies in minority youth and the stress-buffering model posit that ethnic minority youth have unique experiences (e.g., stressors) that can inhibit their developmental pathways, but that supportive relationships can play a buffering role for individuals when in the presence of stressors. The current study examines the associations between parent-child conflict, sleep, and depressive symptoms among 207 Latinx youth (M = 12.39, SD = 1.15; 53% females) while exploring the moderating role of the opposite parent’s warmth. Results revealed positive links between mother-child conflict, sleep, and depressive symptoms and between father-child conflict and depressive symptoms. No evidence was found for the moderating role of parental warmth. This study’s findings contribute to the knowledge on Latinx youth by creating a starting point for potential intervention targets in familial processes.