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Grad School: Human Growth Horror - Creative Project Entry of an Action/Adventure Computer Game Designed to Experimentally Demonstrate Viable Engineering Concepts for Educational Purposes

Description

The action/adventure game Grad School: HGH is the final, extended version of a BME Prototyping class project in which the goal was to produce a zombie-themed game that teaches biomedical

The action/adventure game Grad School: HGH is the final, extended version of a BME Prototyping class project in which the goal was to produce a zombie-themed game that teaches biomedical engineering concepts. The gameplay provides fast paced, exciting, and mildly addicting rooms that the player must battle and survive through, followed by an engineering puzzle that must be solved in order to advance to the next room. The objective of this project was to introduce the core concepts of BME to prospective students, rather than attempt to teach an entire BME curriculum. Based on user testing at various phases in the project, we concluded that the gameplay was engaging enough to keep most users' interest through the educational puzzles, and the potential for expanding this project to reach an even greater audience is vast.

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  • 2014-05

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Engineering Lean, Packaged Energy Systems for Rapid, Economical Deployment and Distributed Generation

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The following document addresses two grand challenges posed to engineers: to make solar energy economically viable and to restore and improve urban infrastructure. Design solutions to these problems consist of

The following document addresses two grand challenges posed to engineers: to make solar energy economically viable and to restore and improve urban infrastructure. Design solutions to these problems consist of the preliminary designs of two energy systems: a Packaged Photovoltaic (PPV) energy system and a natural gas based Modular Micro Combined Cycle (MMCC) with 3D renderings. Defining requirements and problem-solving approach methodology for generating complex design solutions required iterative design and a thorough understanding of industry practices and market trends. This paper briefly discusses design specifics; however, the major emphasis is on aspects pertaining to economical manufacture, deployment, and subsequent suitability to address the aforementioned challenges. The selection of these systems is based on the steady reduction of PV installation costs in recent years (average among utility, commercial, and residential down 27% from Q4 2012 to Q4 2013) and the dramatic decline in natural gas prices to $5.61 per thousand cubic feet. In addition, a large number of utility scale coal-based power plants will be retired in 2014, many due to progressive emission criteria, creating a demand for additional power systems to offset the capacity loss and to increase generating capacity in order to facilitate the ever-expanding world population. The proposed energy systems are not designed to provide power to the masses through a central location. Rather, they are intended to provide economical, reliable, and high quality power to remote locations and decentralized power to community-based grids. These energy systems are designed as a means of transforming and supporting the current infrastructure through distributed electricity generation.

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  • 2014-05

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Design of Rocket Engine Nozzle Ejectors

Description

This work describes the numerical process developed for use of rocket engine nozzle ejectors. Ejector nozzles, while applied to jet engines extensively, have not been applied to rockets, and have

This work describes the numerical process developed for use of rocket engine nozzle ejectors. Ejector nozzles, while applied to jet engines extensively, have not been applied to rockets, and have great potential to improve the performance of endoatmospheric rocket propulsion systems. Utilizing the low pressure, high velocity flow in the plume, this secondary structure entrains a secondary mass flow to increase the mass flow of the propulsion system. Rocket engine nozzle ejectors must be designed with the high supersonic conditions associated with rocket engines. These designs rely on the numerical process described in this paper.

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  • 2014-05

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Developmental Changes in Vascular Density of the Hypothalamic Paraventricular Nucleus Following Prenatal Exposure to Dexamethasone

Description

The goal of the studies described in this thesis was to determine the changes in vascular density in the paraventricular nucleus (PVN) of the hypothalamus following prenatal exposure to the

The goal of the studies described in this thesis was to determine the changes in vascular density in the paraventricular nucleus (PVN) of the hypothalamus following prenatal exposure to the synthetic glucocorticoid hormone, dexamethasone (DEX). DEX is a synthetic glucocorticoid used clinically in women at risk for preterm delivery or in preterm infants to promote proper pulmonary development in high-risk neonates. Prenatal exposure to glucocorticoids such as DEX may change the development of important brain regulatory centers such as the PVN, resulting in increased risk for diseases in adulthood.
Previous studies have demonstrated that the hypothalamus regulates neuroendocrine and autonomic function and behavior. Within the hypothalamus, the paraventricular nucleus (PVN) is an integratory node that contains neurons associated with the control of neuroendocrine and autonomic responses. The PVN also has one of the highest density of blood vessels within the brain. Alterations of normal PVN angiogenesis by dexamethasone could potentially result in long-term modifications of brain and endocrine functions.
Timed-pregnant Sprague Dawley female rats received DEX on gestational days 18-21 and the resulting progeny were sacrificed at Postnatal Day (PND) 0, 4, 14, and 21. A tomato lectin, Lycopersicon Esculentum labeled with DyLight594 was used to stain blood vessels in the PVN and scanning confocal microscopy was used to analyze the experimental brains for PVN blood vessel density
Analysis of data using a 3-way analysis of variance (ANOVA) with age, sex and treatment as main factors, showed a significant age effect in vascular density. Analysis of female data by 2-way ANOVA demonstrated a significant effect of age, but no treatment or interaction effects. Post-hoc analysis shows significant differences at PND 2, 4, 14, and 21 compared to PND0. A Student‘s t-test of a planned comparison on PND2 showed a significant reduction by DEX treatment (p < 0.05). Analysis of data from females, using 2-way ANOVA demonstrated a significant effect of age, but no treatment or interaction effects. Post-hoc analysis shows significant differences at PND 2, 4, 14, and 21 compared to PND0. A planned comparison at PND 2 using Student’s t-test indicated a significant reduction by dex treatment.
The results of these studies demonstrate that there is significant postnatal angiogenic programming and that the vascular density of the PVN is altered by prenatal dexamethasone administration at PND2. The time-course shows developmental fluctuations in vessel density that may prove to be physiologically significant for normal brain function and developmental programming of brain and behavior.

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  • 2014-05

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Design of a Gravity-Fed Hydrodynamic Testing Tunnel

Description

The purpose of this project is to determine the feasibility of a water tunnel designed to meet certain constraints. The project goals are to tailor a design for a given

The purpose of this project is to determine the feasibility of a water tunnel designed to meet certain constraints. The project goals are to tailor a design for a given location, and to produce a repeatable design sizing and shape process for specified constraints. The primary design goals include a 1 m/s flow velocity in a 30cm x 30cm test section for 300 seconds. Secondary parameters, such as system height, tank height, area contraction ratio, and roof loading limits, may change depending on preference, location, or environment. The final chosen configuration is a gravity fed design with six major components: the reservoir tank, the initial duct, the contraction nozzle, the test section, the exit duct, and the variable control exit nozzle. Important sizing results include a minimum water weight of 60,000 pounds, a system height of 7.65 meters, a system length of 6 meters (not including the reservoir tank), a large shallow reservoir tank width of 12.2 meters, and height of 0.22 meters, and a control nozzle exit radius range of 5.25 cm to 5.3 cm. Computational fluid dynamic simulation further supports adherence to the design constraints but points out some potential areas for improvement in dealing with flow irregularities. These areas include the bends in the ducts, and the contraction nozzle. Despite those areas recommended for improvement, it is reasonable to conclude that the design and process fulfill the project goals.

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  • 2014-05

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Electric Field Sensing

Description

This project examines the science of electric field sensing and completes experiments, gathering data to support its utility for various applications. The basic system consists of a transmitter, receiver, and

This project examines the science of electric field sensing and completes experiments, gathering data to support its utility for various applications. The basic system consists of a transmitter, receiver, and lock-in amplifier. The primary goal of the study was to determine if such a system could detect a human disturbance, due to the capacitance of a human body, and such a thesis was supported. Much different results were obtained when a person disturbed the electric field transmitted by the system than when other types of objects, such as chairs and electronic devices, were placed in the field. In fact, there was a distinct difference between persons of varied sizes as well. This thesis goes through the basic design of the system and the process of experimental design for determining the capabilities of such an electric field sensing system.

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  • 2013-05

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An Economic Perspective -- Hybrid Solar Modules: Harnessing Solar Energy for Electrical and Thermal Applications

Description

A hybrid PV/T module was built, consisting of a thermal liquid heating system and a photovoltaic module system that combine in a hybrid format. This report will discuss the work

A hybrid PV/T module was built, consisting of a thermal liquid heating system and a photovoltaic module system that combine in a hybrid format. This report will discuss the work on the project from Fall 2012 to Spring 2013 and the extended section on the economics for the Honors Thesis. Three stages of experiments were completed. Stage 1 showed our project was functional as we were able to verify our panel produced electricity and increased the temperature of water flowing in the system by 0.65°C. Stage 2 testing included “gluing” the flow system to the back of the panel resulting in an average increase of 4.76°C in the temperature of the water in the system. Stage 3 testing included adding insulating foam to the module which resulted in increasing the average temperature of the water in our flow system by 6.95°C. The economic calculations show the expected energy cost savings for Arizona residents.

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  • 2013-05

BIOELECTRIC IMPEDANCE ANALYSIS AS A METHOD FOR QUANTITATIVE HYDRATION MEASUREMENT

Description

Volume depletion can lead to migraines, dizziness, and significant decreases in a subject's ability to physically perform. A major cause of volume depletion is dehydration, or loss in fluids due

Volume depletion can lead to migraines, dizziness, and significant decreases in a subject's ability to physically perform. A major cause of volume depletion is dehydration, or loss in fluids due to an imbalance in fluid intake to fluid excretion. Because proper levels of hydration are necessary in order to maintain both short and long term health, the ability to monitor hydration levels is growing in clinical demand. Although devices capable of monitoring hydration level exist, these devices are expensive, invasive, or inaccurate and do not offer a continuous mode of measurement. The ideal hydration monitor for consumer use needs to be characterized by its portability, affordability, and accuracy. Also, this device would need to be noninvasive and offer continuous hydration monitoring in order to accurately assess fluctuations in hydration data throughout a specified time period. One particular method for hydration monitoring that fits the majority of these criteria is known as bioelectric impedance analysis (BIA). Although current devices using BIA do not provide acceptable levels of accuracy, portability, or continuity in data collection, BIA could potentially be modified to fit many, if not all, desired customer specifications. The analysis presented here assesses the viability of using BIA as a new standard in hydration level measurement. The analysis uses data collected from 22 subjects using an existing device that employs BIA. A regression derived for estimating TBW based on the parameters of age, weight, height, sex, and impedance is presented. Using impedance data collected for each subject, a regression was also derived for estimating impedance based on the factors of age, weight, height, and sex. The derived regression was then used to calculate a new impedance value for each subject, and these new impedance values were used to estimate TBW. Through a paired-t test between the TBW values derived by using the direct measurements versus the calculated measurements of impedance, the two samples were found to be comparable. Considerations for BIA as a noninvasive measurement of hydration are discussed.

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  • 2013-05

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Exhaust System Design and Testing Methods

Description

The exhaust system is an integral part of any internal combustion engine. A well- designed exhaust system efficiently removes exhaust gasses expelled from the cylinders. If tuned for performance purposes,

The exhaust system is an integral part of any internal combustion engine. A well- designed exhaust system efficiently removes exhaust gasses expelled from the cylinders. If tuned for performance purposes, the exhaust system can also exhibit scavenging and supercharging characteristics. This project reviews the major components of an exhaust system and discusses the proper design techniques necessary to utilize the performance boosting potential of a tuned exhaust system for a four-stroke engine. These design considerations are then applied to Arizona State University's Formula SAE vehicle by comparing the existing system to a properly tuned system. An inexpensive testing method, developed specifically for this project, is used to test the effectiveness of the current design. The results of the test determined that the current design is ineffective at scavenging neighboring pipes of exhaust gasses and should be redesigned for better performance.

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  • 2014-05

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Statistical Analysis of Power Differences between Experimental Design Software Packages

Description

Based on findings of previous studies, there was speculation that two well-known experimental design software packages, JMP and Design Expert, produced varying power outputs given the same design and user

Based on findings of previous studies, there was speculation that two well-known experimental design software packages, JMP and Design Expert, produced varying power outputs given the same design and user inputs. For context and scope, another popular experimental design software package, Minitab® Statistical Software version 17, was added to the comparison. The study compared multiple test cases run on the three software packages with a focus on 2k and 3K factorial design and adjusting the standard deviation effect size, number of categorical factors, levels, number of factors, and replicates. All six cases were run on all three programs and were attempted to be run at one, two, and three replicates each. There was an issue at the one replicate stage, however—Minitab does not allow for only one replicate full factorial designs and Design Expert will not provide power outputs for only one replicate unless there are three or more factors. From the analysis of these results, it was concluded that the differences between JMP 13 and Design Expert 10 were well within the margin of error and likely caused by rounding. The differences between JMP 13, Design Expert 10, and Minitab 17 on the other hand indicated a fundamental difference in the way Minitab addressed power calculation compared to the latest versions of JMP and Design Expert. This was found to be likely a cause of Minitab’s dummy variable coding as its default instead of the orthogonal coding default of the other two. Although dummy variable and orthogonal coding for factorial designs do not show a difference in results, the methods affect the overall power calculations. All three programs can be adjusted to use either method of coding, but the exact instructions for how are difficult to find and thus a follow-up guide on changing the coding for factorial variables would improve this issue.

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  • 2017-05