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In the medical industry, there have been promising advances in the increase of new types of healthcare to the public. As of 2015, there was a 98% Premarket Approval rate, a 38% increase since 2010. In addition, there were 41 new novel drugs approved for clinical usage in 2014 where

In the medical industry, there have been promising advances in the increase of new types of healthcare to the public. As of 2015, there was a 98% Premarket Approval rate, a 38% increase since 2010. In addition, there were 41 new novel drugs approved for clinical usage in 2014 where the average in the previous years from 2005-2013 was 25. However, the research process towards creating and delivering new healthcare to the public remains remarkably inefficient. It takes on average 15 years, over $900 million by one estimate, for a less than 12% success rate of discovering a novel drug for clinical usage. Medical devices do not fare much better. Between 2005-2009, there were over 700 recalls per year. In addition, it takes at minimum 3.25 years for a 510(k) exempt premarket approval. Plus, a time lag exists where it takes 17 years for only 14% of medical discoveries to be implemented clinically. Coupled with these inefficiencies, government funding for medical research has been decreasing since 2002 (2.5% of Gross Domestic Product) and is predicted to be 1.5% of Gross Domestic Product by 2019. Translational research, the conversion of bench-side discoveries to clinical usage for a simplistic definition, has been on the rise since the 1990s. This may be driving the increased premarket approvals and new novel drug approvals. At the very least, it is worth considering as translational research is directly related towards healthcare practices. In this paper, I propose to improve the outcomes of translational research in order to better deliver advancing healthcare to the public. I suggest Best Value Performance Information Procurement System (BV PIPS) should be adapted in the selection process of translational research projects to fund. BV PIPS has been shown to increase the efficiency and success rate of delivering projects and services. There has been over 17 years of research with $6.3 billion of projects and services delivered showing that BV PIPS has a 98% customer satisfaction, 90% minimized management effort, and utilizes 50% less manpower and effort. Using University of Michigan \u2014 Coulter Foundation Program's funding process as a baseline and standard in the current selection of translational research projects to fund, I offer changes to this process based on BV PIPS that may ameliorate it. As concepts implemented in this process are congruent with literature on successful translational research, it may suggest that this new model for selecting translational research projects to fund will reduce costs, increase efficiency, and increase success. This may then lead to more Premarket Approvals, more new novel drug approvals, quicker delivery time to the market, and lower recalls.
ContributorsDel Rosario, Joseph Paul (Author) / Kashiwagi, Dean (Thesis director) / Kashiwagi, Jacob (Committee member) / Harrington Bioengineering Program (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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This abstract is intended to explain the main ideas and thoughts pertaining to the author's experiences over time while attending Arizona State University and how certain course teachings have created a more positive outcome in life for the author. The goal of this Independent Study Thesis is to convey the

This abstract is intended to explain the main ideas and thoughts pertaining to the author's experiences over time while attending Arizona State University and how certain course teachings have created a more positive outcome in life for the author. The goal of this Independent Study Thesis is to convey the great significance that the Information Measurement Theory (IMT) courses' ideas and teachings have contributed to the author's life and how they have increased the author's overall quality and outlook on life, not only from an academic standpoint and setting, but also in every facet. Based on this, the author's intention is to convey the new skills obtained regarding The Kashiwagi Solution Model (KSM) as they pertain to Information Measurement Theory (IMT), based on the author's own recent experiences in college with what he has learned, and to explain how they have helped tremendously. This is mainly comprised of information based on the external sources and writings of Dr. Dean Kashiwagi, and also direct resources and teachings by Dr. Dean Kashiwagi and Dr. Jacob Kashiwagi that have greatly contributed to the author's overall understanding of Information Measurement Theory (IMT), its revolutionary new ways of thinking, and the new skill sets developed from it as well. This will also focus on the benefits that can occur for anyone by applying the various aspects of The Kashiwagi Solution Model (KSM), through the use of the concepts of Information Measurement Theory (IMT), and to convey the author's findings pertinent to helping mitigate stress in life, while also being able to enter into any situation or event with a more positive mindset in order to help conclude that event successfully and with the increased potential for a more positive outcome. This idea of always striving to have a more positive mindset in order to complete a task, goal, or event in life in a more positive and successful way is exactly what the author will focus on, mostly pertaining to the author's own life experiences, referred to as Mind Over Matter with IMT. This Thesis idea of Mind Over Matter with IMT stems from some of the main aspects that the author found to be most impressive and significant in the honors courses offered at ASU by Dr. Dean Kashiwagi and Dr. Jacob Kashiwagi, mainly because of the fact that they inform students of some new ways to help mitigate stresses and anxieties in their lives and to more accurately predict the outcome of future events based on using deductive logic and expertise. This leads to focusing more on dominant information in order to obtain the key ideas and main points of any situation, rather than requiring additional and superfluous details, data, and minutia. The fact that the courses also focus on natural laws and initial conditions of events have proven to be extremely useful because of their significant importance to determining the final conditions and concluding outcome of events, of which many people tend to not even be aware at first when initially learning about Information Measurement Theory (IMT). Because of this, the Deductive Logic and Information Measurement Theory courses offered at ASU have proven to offer invaluable insight, great knowledge, unique ideas, and alternative ways of thinking to the author, which have contributed greatly to the author's increased success as a student enrolled at Arizona State University over these past years. Keywords: Kashiwagi Solution Model (KSM); Information Measurement Theory (IMT); Deductive Logic; initial conditions; final conditions; natural law; Mind Over Matter
ContributorsFranklin, Sean Donothan (Author) / Kashiwagi, Dean (Thesis director) / Kashiwagi, Jacob (Committee member) / College of Letters and Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2015-05
Description
Over the past 3 semesters, I have been learning the theories of Information Measurement Theory and Kashiwagi Solution Model and implementing them into my life as a means of improving happiness and well being, and reducing stress and conflict. Before IMT and KSM, external control played a huge role in

Over the past 3 semesters, I have been learning the theories of Information Measurement Theory and Kashiwagi Solution Model and implementing them into my life as a means of improving happiness and well being, and reducing stress and conflict. Before IMT and KSM, external control played a huge role in my life and my interactions with other people. I was judgmental, selfish, and lazy while using blame and deflection of responsibility to avoid self-control. This led me to become very unhappy and live in constant stress. Culminating in a difficult shortcoming that magnified the negative ways in which I had been living my life, I decided that I had to change. Since implementing IMT and KSM into my life and accepting self-responsibility, I have dramatically improved my happiness and reduced stress and conflict. I have lost 85 pounds, went from working 1 job to 4 to gain financial independence, made my best grades in college, stopped wasting time and valued free time more, improved my relationships with people in my environment, and learned more about myself. All of this change required me to commit to a new way of thinking and recognize that my previous way of thinking was inaccurate and unsustainable if I truly wanted to change. Upon making positive changes in my life, I believe that adapting IMT and KSM played fundamental roles in my ability to perceive information around me and I would not have experienced the change I did if it was not for exposure to the theories. Not only do I believe IMT and KSM served as catalysts for change in my life, but believe IMT and KSM can be applied to every aspect of life and be used by others in the same approach.
ContributorsSmith, Hunter Christian (Author) / Kashiwagi, Dean (Thesis director) / Kashiwagi, Jacob (Committee member) / Barrett, The Honors College (Contributor) / W. P. Carey School of Business (Contributor) / School of Life Sciences (Contributor)
Created2015-05
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Description
The introduction of novel information technology within contemporary healthcare settings presents a critical juncture for the industry and thus lends itself to the importance of better understanding the impact of this emerging "health 2.0" landscape. Simply, how such technology may affect the healthcare system is still not fully realized, despite

The introduction of novel information technology within contemporary healthcare settings presents a critical juncture for the industry and thus lends itself to the importance of better understanding the impact of this emerging "health 2.0" landscape. Simply, how such technology may affect the healthcare system is still not fully realized, despite the ever-growing need to adopt it in order to serve a growing patient population. Thus, two pertinent questions are posed: is HIT useful and practical and, if so, what is the best way to implement it? This study examined the clinical implementation of specific instances of health information technology (HIT) so as to weigh its benefits and risks to ultimately construct a proposal for successful widespread adoption. Due to the poignancy of information analysis within HIT, Information Measurement Theory (IMT) was used to measure the effectiveness of current HIT systems as well as to elucidate improvements for future implementation. The results indicate that increased transparency, attention to patient-focused approaches and proper IT training will not only allow HIT to better serve the community, but will also decrease inefficient healthcare expenditure.
ContributorsMaietta, Myles Anthony (Author) / Kashiwagi, Dean (Thesis director) / Kashiwagi, Jacob (Committee member) / Barrett, The Honors College (Contributor) / Department of Psychology (Contributor) / School of Life Sciences (Contributor)
Created2015-05
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Description
Exercise is a great boon to both the health of individuals and the national as a whole. Exercise provides a wide range of significant and well established benefits to both physical and psychological health, with many benefits that are still being discovered. The effects of exercise on health are somewhat

Exercise is a great boon to both the health of individuals and the national as a whole. Exercise provides a wide range of significant and well established benefits to both physical and psychological health, with many benefits that are still being discovered. The effects of exercise on health are somewhat unique, as exercise is one of a limited number of ways to improve health that is not harm a reduction strategy, but instead increases health through direct benefit, rather than increasing health by decreasing damage and harm. Support is also given to the proposal that individuals are in best position to determine the intensity of exercise and to choose primary activities to participate in, in order to provide near maximum physical and psychological benefit, with the understanding that frequency of exercise is of the upmost importance for benefit. The accessibility of exercise and the tremendous health benefit of exercise, makes exercise a huge asset in reducing the exorbitant health care spending and improving mediocre health outcomes in this country; a reasonable goal as numerous countries have better health the United States, even though the United States spends the more than any other country on health.
ContributorsRael, Ashur Scott (Author) / Kashiwagi, Dean (Thesis director) / Kashiwagi, Jacob (Committee member) / Barrett, The Honors College (Contributor) / Department of Chemistry and Biochemistry (Contributor) / School of Film, Dance and Theatre (Contributor)
Created2015-05
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Description
The construction industry is inefficient. Technological advancements alone do not provide a full solution. By simplifying the complexity of a construction project, and implementing the views of IMT (Information Measurement Theory) through a value driven system, the construction industry can be improved. In Bechtel's recent film, Dream Big: Engineering our

The construction industry is inefficient. Technological advancements alone do not provide a full solution. By simplifying the complexity of a construction project, and implementing the views of IMT (Information Measurement Theory) through a value driven system, the construction industry can be improved. In Bechtel's recent film, Dream Big: Engineering our World, the integration of their company values on emerging engineers resulted in astounding solutions towards making the future of the construction industry more efficient as a whole. This thesis demonstrates how Bechtel was able to direct the Dream Big movement with an emphasis on leadership and simpler thinking of future generations. Under the direction of Dr. Kashiwagi's Research and Solution Model (KSM) it is possible for young people aware of their potential and understand "simplicity" to be effective leaders. Through observation, these new leaders understand that they have been making a difference since their birth. As individuals are able to identify their core values, they are better able to find their strengths, align their values with a company, and ultimately make the construction industry more efficient.
ContributorsPirkl, Amber Victoria (Author) / Kashiwagi, Dean (Thesis director) / Kashiwagi, Jacob (Committee member) / Del E. Webb Construction (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
Description
The Performance Based Studies Research Group (PBSRG) uses a leading model that helps people and procurement projects alike minimize risk while maximizing productivity. While there are a multitude of factors that propel this model, Information Measurement Theory (IMT) is the main element of the Best Value approach the group takes.

The Performance Based Studies Research Group (PBSRG) uses a leading model that helps people and procurement projects alike minimize risk while maximizing productivity. While there are a multitude of factors that propel this model, Information Measurement Theory (IMT) is the main element of the Best Value approach the group takes. I wanted to take the dominant information elements of IMT that helped me find my true self and increase my level of efficiency, and use them to find what it takes to become a successful veterinarian. In order to do this, the Kashiwagi Solution Model (KSM) within IMT was the perfect way to distinguish more successful, higher performing veterinarians from the less successful, lower performing veterinarians. In order to do this, a number of KSM-designed questions were created to score each veterinarian's level of perception. These, along with other background and performance questions, were put into a short survey and sent out. Once this was done, other elements of the veterinarians' lives could be compared side by side to their perception level. The results, of which 970 surveys were returned, found that the more expert a veterinarian is, the lower number of animals they will see per day and the better they know their customer satisfaction rating. These are both then theorized to work in conjunction to form the final correlation that the more perceptive the veterinarian, the higher their performance, aka their clinic's rating. In addition to this, no correlation was found between a veterinarian's level of thinking and their GPA from graduate school. It was concluded that though these correlations are found, I would recommend another project to be done in which all veterinarians of each surveyed clinic could be analyzed in order to gain more insight into any trends that exist between a veterinarian's level of thinking and their performance.
ContributorsBoon, Kurtis Ventry (Author) / Kashiwagi, Jacob (Thesis director) / Finney, Gina Lee (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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Description
The Information Measurement Theory (IMT) states that all information exists at any time and all the time, and that it's an individual lack of ability to perceive that creates the misperception that there is an absence of information. This lack of perceived information creates subjective bias and limitations. IMT identifies

The Information Measurement Theory (IMT) states that all information exists at any time and all the time, and that it's an individual lack of ability to perceive that creates the misperception that there is an absence of information. This lack of perceived information creates subjective bias and limitations. IMT identifies decision-making and bias as the major obstacles to perfectly understanding reality. This study examines the IMT's correlation to romantic relationships and is designed to determine what factors and traits makes a romantic relationship successful. We collected data on 123 subjects: 56 individuals who were in committed romantic relationships and 67 individuals who were not. These individuals were asked fundamental questions on the IMT theory as well as their thoughts on what they define as a successful relationship. Participants in relationships were asked questions relating to their overall satisfaction level. Correlations were calculated between these satisfaction levels and an individual's perception of information. This study's overarching goal is to understand if successful relationships are determined by how much dominant information each individual involved in the relationship knows about each other, themselves, and other external factors.
ContributorsWang, Celina (Co-author) / Zeng, Carrie (Co-author) / Cao, Quynh-mi (Co-author) / Kashiwagi, Dean (Thesis director) / Kashiwagi, Jacob (Committee member) / Department of Information Systems (Contributor) / W. P. Carey School of Business (Contributor) / Department of Marketing (Contributor) / School of Social Transformation (Contributor) / Department of Supply Chain Management (Contributor) / School of Accountancy (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
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Description
Homelessness is a pervasive in American society. The causes of homelessness are complex, but health and homelessness are inextricably linked. Student-run free clinics care for underserved populations, including people experiencing homelessness, but they have multiple agendas—to provide care but also to give students hands-on experience. It is plausible that these

Homelessness is a pervasive in American society. The causes of homelessness are complex, but health and homelessness are inextricably linked. Student-run free clinics care for underserved populations, including people experiencing homelessness, but they have multiple agendas—to provide care but also to give students hands-on experience. It is plausible that these two agendas may compete and give patients sub-par quality of care.
This study examines patient care in the SHOW free clinic in Phoenix, Arizona, which serves adults experiencing homelessness. This study asks two questions: First, do clinicians in Phoenix’s SHOW free clinic discuss with patients how to pay for and where to access follow-up services and medications? Second, how do the backgrounds of patients, measured by scales based on the Gelberg-Anderson behavioral model for vulnerable populations, correlate with patient outcomes, including number of unmet needs in clinic, patient satisfaction with care, and patient perceived health status? To answer these questions, structured surveys were administered to SHOW clinic patients at the end of their visits. Results were analyzed using Pearson’s correlations and odds ratios. 21 patients completed the survey over four weeks in February-March 2017. We did not identify any statistically significant correlations between predisposing factors such as severity/duration of homelessness, mental health history, ethnicity, or LGBTQ status and quality of care outcomes. Twenty nine percent of surveyed patients reported having one or more unmet needs following their SHOW clinic visit suggesting an important area for future research. The results from this study indicate that measuring unmet needs is a feasible alternative to patient satisfaction surveys for assessing quality of care in student-run free clinics for homeless populations.
ContributorsWilson, Ethan Sinead (Author) / Jehn, Megan (Thesis director) / Harrell, Susan (Committee member) / School of Human Evolution and Social Change (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
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Description
Information Measurement Theory (IMT) is a concept which was devised for the purpose of understanding how information works in the universe. At its core, it states that 100% of information exists in the universe at any one time, and with enough perception, any event can be predicted based on the

Information Measurement Theory (IMT) is a concept which was devised for the purpose of understanding how information works in the universe. At its core, it states that 100% of information exists in the universe at any one time, and with enough perception, any event can be predicted based on the initial conditions preceding the event. With this idea in mind, the author of IMT developed the Kashiwagi Solution Model (KSM) which deals with how people best utilize the information present in the universe. Simply put, the ideas presented by KSM encourage people to think in a more logical manner through the utilization of relevant information. The following thesis details an autobiographical case study which focuses on the life of a college student undergoing severe depressive symptoms during the course of their academic career. The usage of concepts stemming from IMT and KSM are then used to determine the root causes of the depression in order to prevent it from ever happening again. The case study acts as a guide to others in order to better help them deal with similar situations that are happening with their lives while providing evidence that the concepts detailed by IMT and KSM are factually relevant.
ContributorsChauhan, Amit (Author) / Kashiwagi, Dean (Thesis director) / Kashiwagi, Jacob (Committee member) / Barrett, The Honors College (Contributor)
Created2016-05