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The COVID-19 pandemic has resulted in preventative measures and has led to extensive changes in lifestyle for the vast majority of the American population. As the pandemic progresses, a growing amount of evidence shows that minority groups, such as the Deaf community, are often disproportionately and uniquely affected. Deaf

The COVID-19 pandemic has resulted in preventative measures and has led to extensive changes in lifestyle for the vast majority of the American population. As the pandemic progresses, a growing amount of evidence shows that minority groups, such as the Deaf community, are often disproportionately and uniquely affected. Deaf people are directly affected in their ability to personally socialize and continue with daily routines. More specifically, this can constitute their ability to meet new people, connect with friends/family, and to perform in their work or learning environment. It also may result in further mental health changes and an increased reliance on technology. The impact of COVID-19 on the Deaf community in clinical settings must also be considered. This includes changes in policies for in-person interpreters and a rise in telehealth. Often, these effects can be representative of the pre-existing low health literacy, frequency of miscommunication, poor treatment, and the inconvenience felt by Deaf people when trying to access healthcare. Ultimately, these effects on the Deaf community must be taken into account when attempting to create a full picture of the societal shift caused by COVID-19.

ContributorsDubey, Shreya Shashi (Co-author) / Asuncion, David Leonard (Co-author) / Patterson, Lindsey (Thesis director) / Lee, Lindsay (Committee member) / School of Molecular Sciences (Contributor) / School of Mathematical and Statistical Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Description

As much as SARS-CoV-2 has altered the way humans live since the beginning of 2020, this virus's deadly nature has required clinical testing to meet 2020's demands of higher throughput, higher accuracy and higher efficiency. Information technology has allowed institutions, like Arizona State University (ASU), to make strategic and operational

As much as SARS-CoV-2 has altered the way humans live since the beginning of 2020, this virus's deadly nature has required clinical testing to meet 2020's demands of higher throughput, higher accuracy and higher efficiency. Information technology has allowed institutions, like Arizona State University (ASU), to make strategic and operational changes to combat the SARS-CoV-2 pandemic. At ASU, information technology was one of the six facets identified in the ongoing review of the ASU Biodesign Clinical Testing Laboratory (ABCTL) among business, communications, management/training, law, and clinical analysis. The first chapter of this manuscript covers the background of clinical laboratory automation and details the automated laboratory workflow to perform ABCTL’s COVID-19 diagnostic testing. The second chapter discusses the usability and efficiency of key information technology systems of the ABCTL. The third chapter explains the role of quality control and data management within ABCTL’s use of information technology. The fourth chapter highlights the importance of data modeling and 10 best practices when responding to future public health emergencies.

ContributorsLeung, Michael (Co-author) / Kandan, Mani (Co-author) / Knox, Garrett (Co-author) / Woo, Sabrina (Co-author) / Compton, Carolyn (Thesis director) / Dudley, Sean (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Description

During the COVID-19 pandemic, increased burdens have been placed on the Arizona healthcare system, and its healthcare providers. Using a survey with a sample of N=308 prescribing providers and nurses in the Arizona healthcare system, the impact of COVID-19 on the wellbeing of healthcare providers was assessed. The survey used

During the COVID-19 pandemic, increased burdens have been placed on the Arizona healthcare system, and its healthcare providers. Using a survey with a sample of N=308 prescribing providers and nurses in the Arizona healthcare system, the impact of COVID-19 on the wellbeing of healthcare providers was assessed. The survey used measures to evaluate for physical and emotional wellbeing, burnout, stressors associated with COVID-19, and work-life experiences, and found an overall negative impact on the wellbeing of healthcare workers during the COVID-19 pandemic with increased levels of reported stress and tiredness, concern for the health of family and loved ones, concern for the hardships of patients, lack of alignment between organizational priorities and personal values, and low levels of support and appreciation from socially and from leadership at work.

ContributorsJohnson, Emma Carina (Author) / Schuster, Roseanne (Thesis director) / Michalec, Barret (Committee member) / School of Molecular Sciences (Contributor) / School of Human Evolution & Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description

The COVID-19 pandemic has renewed interest in the importance of indoor air quality for health. The spread of respiratory aerosols is the primary mechanism for COVID-19 transmission, making it crucial to understand the role of effective ventilation in managing the risk of disease transmission. The concentration of exhaled carbon dioxide

The COVID-19 pandemic has renewed interest in the importance of indoor air quality for health. The spread of respiratory aerosols is the primary mechanism for COVID-19 transmission, making it crucial to understand the role of effective ventilation in managing the risk of disease transmission. The concentration of exhaled carbon dioxide (CO2) in indoor spaces can be used as a proxy measure of ventilation efficiency. Poor indoor air quality has been associated with a range of acute and chronic health problems, including respiratory issues, cardiovascular disease, and cancer. Poor air quality may also impair cognitive performance and productivity. Social and economic inequalities exacerbate the impact of indoor air quality issues, making it crucial to address these problems in an equitable manner. Public libraries have been identified as an effective intermediary for providing education and free air quality monitoring technology to communities, with the ultimate goal of promoting awareness and increasing access to tools to promote accountability for maintaining high indoor air quality standards. The primary objectives of this initiative are to: 1) develop a citizen science toolkit for assessing indoor air quality in public spaces and deploy the toolkit to public libraries in Arizona; and 2) to conduct a program evaluation to determine whether this kit can be effectively deployed through public libraries to promote citizen science efforts and engage community members in promoting healthier indoor air quality, identify areas where improvements can be made, and prepare the program to be scaled to a larger audience.

ContributorsYoung, Parker (Author) / Jehn, Megan (Thesis director) / Cavalier, Darlene (Committee member) / Barrett, The Honors College (Contributor) / School of Molecular Sciences (Contributor) / School of International Letters and Cultures (Contributor)
Created2023-05
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Description
Coronavirus disease 2019 (COVID-19), an illness caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has been responsible for significant social and economic
disruption, prompting an urgent search for therapeutic solutions. The spike protein of the virus
has been examined as an immunogenic target because of its role in viral binding and fusion
necessary

Coronavirus disease 2019 (COVID-19), an illness caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has been responsible for significant social and economic
disruption, prompting an urgent search for therapeutic solutions. The spike protein of the virus
has been examined as an immunogenic target because of its role in viral binding and fusion
necessary for infection of host cells. Previous studies have identified a recombinant protein
(denoted as S1) that has been shown to potentially induce a neutralizing antibody response by
mimicking the structure of the SARS-CoV-2 spike protein. We have produced the S1 in plants
using agroinfiltration, a plant transformation technique whereby plasmid-containing
Agrobacterium tumefaciens is injected into Nicotiana benthamiana plants, resulting in transfer of
the desired gene from bacteria to plant cells. S1 was expressed to high levels within 5 days of
infiltration, and Western blot analysis showed recognition of the S1 by an anti-S1 antibody.
ELISA results exhibited increased binding activity to anti-S1 with increasing concentrations of
S1, indicating their specific interaction. This ongoing study will demonstrate the potential of a
plant-produced S1 as a vaccine, therapeutic, and diagnostic tool against COVID-19 that is not
only effective, but also cost-efficient and scalable in comparison to conventional mammalian cell
culture production methods.
ContributorsNguyen, Katherine (Author) / Chen, Qiang (Thesis director) / Ghirlanda, Giovanna (Committee member) / Jugler, Collin (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
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Description

Archival data for 32 countries were collected and a bivariate correlational analysis was run to determine any correlations between the predictors (tightness and individualism) and predicted variables (health outcomes and social behaviors).

ContributorsHsu, Michael (Author) / Sau-Kwan, Virginia (Thesis director) / Mujica, Vladimiro (Committee member) / Bunker, Cameron (Committee member) / Barrett, The Honors College (Contributor) / School of Molecular Sciences (Contributor) / School of International Letters and Cultures (Contributor)
Created2022-05
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Description

Our thesis project is a 5-person group thesis that was created over the span of two years. In the summer of 2020, at the height of the first wave of the COVID-19 pandemic, our group first met and discussed our shared interests in mask-wearing and individual factors that we each

Our thesis project is a 5-person group thesis that was created over the span of two years. In the summer of 2020, at the height of the first wave of the COVID-19 pandemic, our group first met and discussed our shared interests in mask-wearing and individual factors that we each thought had significant impacts on mask-wearing among Barrett students. We each decided on factors that we wanted to investigate and subsequently split into three main groups based on our interests: culture and geography, medical humanities, and medical and psychological conditions. Despite these different interests, we continued to treat our thesis as a five-person project rather than three different projects. We then constructed a survey, followed by several focus group sessions and interview questions to ask Honors students. In January 2021, we received approval from the IRB for our project, and we quickly finalized our survey, focus group and interview questions. In February 2021, we sent out our survey via the Barrett Digest, which we kept open for approximately one month. We also sent out advertisements for our survey via social media platforms such as Twitter and Discord. Following completion of the survey, we contacted all of the respondents who stated that they were interested in participating in focus groups and interviews. Focus groups and interviews were conducted in March and April 2021, and results were analyzed and correlated to our individual subtopics. Each of the focus group and interview participants received $50 each, and three randomly-selected students who completed the survey received $25 each. From April 2021 until April 2022, we analyzed our results, came to conclusions based on our initial topics of interest, and constructed our paper.

ContributorsWeinstock, Benjamin (Author) / Battista-Palmer, Madison (Co-author) / Chen, Brianna (Co-author) / Harmanian, Tiffany (Co-author) / Siefert, Talia (Co-author) / Helitzer, Deborah (Thesis director) / Davis, Olga (Thesis director) / O'Flaherty, Katherine (Committee member) / Barrett, The Honors College (Contributor) / School of Molecular Sciences (Contributor)
Created2022-05
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Description

Our thesis project is a 5-person group thesis that was created over the span of two years. In the summer of 2020, at the height of the first wave of the COVID-19 pandemic, our group first met and discussed our shared interests in mask-wearing and individual factors that we each

Our thesis project is a 5-person group thesis that was created over the span of two years. In the summer of 2020, at the height of the first wave of the COVID-19 pandemic, our group first met and discussed our shared interests in mask-wearing and individual factors that we each thought had significant impacts on mask-wearing among Barrett students. We each decided on factors that we wanted to investigate and subsequently split into three main groups based on our interests: culture and geography, medical humanities, and medical and psychological conditions. Despite these different interests, we continued to treat our thesis as a five-person project rather than three different projects. We then constructed a survey, followed by several focus group sessions and interview questions to ask Honors students. In January 2021, we received approval from the IRB for our project, and we quickly finalized our survey, focus group and interview questions. In February 2021, we sent out our survey via the Barrett Digest, which we kept open for approximately one month. We also sent out advertisements for our survey via social media platforms such as Twitter and Discord. Following completion of the survey, we contacted all of the respondents who stated that they were interested in participating in focus groups and interviews. Focus groups and interviews were conducted in March and April 2021, and results were analyzed and correlated to our individual subtopics. Each of the focus group and interview participants received $50 each, and three randomly-selected students who completed the survey received $25 each. From April 2021 until April 2022, we analyzed our results, came to conclusions based on our initial topics of interest, and constructed our paper.

ContributorsSiefert, Talia (Author) / Weinstock, Benjamin (Co-author) / Chen, Brianna (Co-author) / Battista-Palmer, Madison (Co-author) / Harmanian, Tiffany (Co-author) / Helitzer, Deborah (Thesis director) / Davis, Olga (Thesis director) / O'Flaherty, Katherine (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor) / School of Molecular Sciences (Contributor) / Department of Psychology (Contributor)
Created2022-05
Description

The occurrence of tragedies throughout history, whether it be natural disasters, pandemics, or wars, is inevitable. The way that humans have chosen to respond to destruction and disagreements has also changed. However, something that remains the same is that those with less monetary resources and political power are at a

The occurrence of tragedies throughout history, whether it be natural disasters, pandemics, or wars, is inevitable. The way that humans have chosen to respond to destruction and disagreements has also changed. However, something that remains the same is that those with less monetary resources and political power are at a higher disadvantage whenever the world is under duress or hardship. This propensity (tendency) can be seen through the comparison of two very different yet very profound events in recent history, the COVID-19 pandemic and World War II. The two events are distinct in their time periods, the nature of the disaster that they caused, and the problems that were created by their existence. Although they are very dissimilar, those in the US who had less monetarily were still disadvantaged much more than those who were more affluent. This pattern of disparity is revealed through the use and failure of the supply chain during both events. A supply chain is the sequence of processes involved in the production and distribution of a commodity or service (Supply Chain Definition & Meaning, n.d.). Although the supply chains used in World War II were not as fine-tuned as the ones required to distribute goods around the world today, World War II was instrumental in the refinement and use of the supply chain due to the high demand for goods and personnel across the world. During COVID-19 the quick shift in demand for unprecedented goods and services exposed the inflexibility of the world's largest supply chains, which in turn caused shortages around the world. For the United States government or large global corporations to fix the problems caused by these events, they both turned to the people who bear the majority of the burden of working overtime to account for the loss of goods; those who are most susceptible to the shortages of goods and services: those in lower-income communities.

ContributorsKarlowicz, Elizabeth (Author) / Lee, Christopher (Thesis director) / Wiedmer, Robert (Committee member) / Barrett, The Honors College (Contributor) / Department of Supply Chain Management (Contributor) / School of Molecular Sciences (Contributor)
Created2023-05
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Description

The occurrence of tragedies throughout history, whether it be natural disasters, pandemics, or wars, is inevitable. The way that humans have chosen to respond to destruction and disagreements has also changed. However, something that remains the same is that those with less monetary resources and political power are at a

The occurrence of tragedies throughout history, whether it be natural disasters, pandemics, or wars, is inevitable. The way that humans have chosen to respond to destruction and disagreements has also changed. However, something that remains the same is that those with less monetary resources and political power are at a higher disadvantage whenever the world is under duress or hardship. This propensity (tendency) can be seen through the comparison of two very different yet very profound events in recent history, the COVID-19 pandemic and World War II. The two events are distinct in their time periods, the nature of the disaster that they caused, and the problems that were created by their existence. Although they are very dissimilar, those in the US who had less monetarily were still disadvantaged much more than those who were more affluent. This pattern of disparity is revealed through the use and failure of the supply chain during both events. A supply chain is the sequence of processes involved in the production and distribution of a commodity or service (Supply Chain Definition & Meaning, n.d.). Although the supply chains used in World War II were not as fine-tuned as the ones required to distribute goods around the world today, World War II was instrumental in the refinement and use of the supply chain due to the high demand for goods and personnel across the world. During COVID-19 the quick shift in demand for unprecedented goods and services exposed the inflexibility of the world's largest supply chains, which in turn caused shortages around the world. For the United States government or large global corporations to fix the problems caused by these events, they both turned to the people who bear the majority of the burden of working overtime to account for the loss of goods; those who are most susceptible to the shortages of goods and services: those in lower-income communities.

ContributorsKarlowicz, Elizabeth (Author) / Lee, Christopher (Thesis director) / Wiedmer, Robert (Committee member) / Barrett, The Honors College (Contributor) / Department of Supply Chain Management (Contributor) / School of Molecular Sciences (Contributor)
Created2023-05