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As much as SARS-CoV-2 has altered the way humans live since the beginning of 2020, this virus's deadly nature has required clinical testing to meet 2020's demands of higher throughput, higher accuracy and higher efficiency. Information technology has allowed institutions, like Arizona State University (ASU), to make strategic and operational

As much as SARS-CoV-2 has altered the way humans live since the beginning of 2020, this virus's deadly nature has required clinical testing to meet 2020's demands of higher throughput, higher accuracy and higher efficiency. Information technology has allowed institutions, like Arizona State University (ASU), to make strategic and operational changes to combat the SARS-CoV-2 pandemic. At ASU, information technology was one of the six facets identified in the ongoing review of the ASU Biodesign Clinical Testing Laboratory (ABCTL) among business, communications, management/training, law, and clinical analysis. The first chapter of this manuscript covers the background of clinical laboratory automation and details the automated laboratory workflow to perform ABCTL’s COVID-19 diagnostic testing. The second chapter discusses the usability and efficiency of key information technology systems of the ABCTL. The third chapter explains the role of quality control and data management within ABCTL’s use of information technology. The fourth chapter highlights the importance of data modeling and 10 best practices when responding to future public health emergencies.

ContributorsWoo, Sabrina (Co-author) / Leung, Michael (Co-author) / Kandan, Mani (Co-author) / Knox, Garrett (Co-author) / Compton, Carolyn (Thesis director) / Dudley, Sean (Committee member) / School of Life Sciences (Contributor) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Developing a vaccine during the midst of a pandemic requires a careful balance between <br/>speed, safety, and efficacy. For the COVID-19 pandemic, the U.S. implemented Operation Warp Speed to accelerate the timeline for vaccine development. The FDA also imposed specific guidelines for granting Emergency Use Authorization (EUA). As of April

Developing a vaccine during the midst of a pandemic requires a careful balance between <br/>speed, safety, and efficacy. For the COVID-19 pandemic, the U.S. implemented Operation Warp Speed to accelerate the timeline for vaccine development. The FDA also imposed specific guidelines for granting Emergency Use Authorization (EUA). As of April 1st, 2021, Operation Warp Speed resulted in three different vaccines receiving EUA, all of which are currently being administered to the public. However, the rapid production and changes in the approval process intensified public scrutiny on the safety and efficacy of the vaccine. This thesis analyzes the differences in fast-tracking a vaccine, which consolidated the authorization process into months rather than years, and delineates the main concerns of the public regarding the COVID-19 vaccine through a media analysis. Although the EUA raised questions about the safety of the vaccine, polls indicate that most Americans would still be willing to receive the vaccine.

ContributorsDykstra, Tatum Nicole (Author) / Brian, Jennifer (Thesis director) / Koskan, Alexis (Committee member) / School of Life Sciences (Contributor) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description

The purpose of this study was to evaluate the pandemic’s effect on the psychosocial and physical quality of life of children with and without classic galactosemia and their parents in the Babble Boot Camp. The Babble Boot Camp within ASU’s Speech and Hearing Genetics Lab provides early intervention speech therapy

The purpose of this study was to evaluate the pandemic’s effect on the psychosocial and physical quality of life of children with and without classic galactosemia and their parents in the Babble Boot Camp. The Babble Boot Camp within ASU’s Speech and Hearing Genetics Lab provides early intervention speech therapy for children with classic galactosemia (CG), evaluating their speech progress as well as other metrics related to stress and quality of life. In this study, the Quality of Life questionnaire (Varni, 1998) was used to measure how three pandemic stages (pre-pandemic, intense-pandemic, post intense-pandemic) affected the entire participant population, those with CG children compared to typically developing, and each family member (father vs. mother vs. child). These factors were combined within an integrated regression model to see driving factors and correlations within responses. The main results were that the pandemic itself did not have a significant effect, but there was quite a significant impact on psychosocial health when comparing affected vs unaffected groups. Evaluating an integrated regression model with the consideration of all three pandemic phases, the results show that the factor driving group differences over time was the affectation of the participant for psychosocial health and family member for physical health. When looking at just pre-pandemic and intense pandemic phase, both models in their entirety were significant, showing that all predictors (affectation, pandemic phase, and family member) drove health differences. Lastly, the findings of the study show that there were significant correlations between the health scores of fathers, mothers, and children throughout the different stages of the pandemic.

ContributorsCordovana, Caitlin (Author) / Nazareno, Andrea (Co-author) / Peter, Beate (Thesis director) / Azuma, Tamiko (Committee member) / Barrett, The Honors College (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / College of Health Solutions (Contributor)
Created2023-05
Description

Studies during and following the height of the Coronavirus pandemic show that psychological and physical health levels decrease, due to factors such as reduced human contact and anxiety. However, there is little to no research on how quality of life levels would change over the course of the pandemic for

Studies during and following the height of the Coronavirus pandemic show that psychological and physical health levels decrease, due to factors such as reduced human contact and anxiety. However, there is little to no research on how quality of life levels would change over the course of the pandemic for families who have the added stress of having a child with a developmental complication. To answer this question, this study utilized longitudinal data from the Babble Boot Camp, a project under the ASU Speech Language Genetics Lab, to analyze quality of life measures in families who have children with Classic Galactosemia (CG). CG is an inborn metabolic disorder that causes an intolerance to galactose, a sugar in dairy, the effects of which can be deadly. These children often show signs of developmental delays in multiple areas within the first few years of life. Studying quality of life surveys before, during, and after the most intense phase of the pandemic, this study investigates the difference between these families and those with typical children.

ContributorsNazareno, Andrea (Author) / Cordovana, Caitlin (Co-author) / Peter, Beate (Thesis director) / Azuma, Tamiko (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor) / Department of Psychology (Contributor)
Created2023-05
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An exploration into the history of the 1918 Influenza Pandemic and the societal impacts associated with it, as well as an analysis of the developing SARS-CoV-2 pandemic today. Based upon these analyses, similarities were drawn between the two pandemics which suggested a lack of innovation in preventative measures over the

An exploration into the history of the 1918 Influenza Pandemic and the societal impacts associated with it, as well as an analysis of the developing SARS-CoV-2 pandemic today. Based upon these analyses, similarities were drawn between the two pandemics which suggested a lack of innovation in preventative measures over the last century. Given this conclusion a series of proposals were made that should be further explored to give not only the United States, but the world at large, a better chance in the face of the next emerging disease.

ContributorsWeinman, Maya (Author) / Martin, Thomas (Thesis director) / Madhavpeddi, Adrienne (Committee member) / College of Health Solutions (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Description

The purpose of this study was to evaluate how COVID-19 has affected college athletes physically and mentally. A survey with 36 questions encompassing gender, sport, COVID-19 symptom severity, type and duration, return to play factors, perceived social isolation, depression and anxiety was distributed to all student athletes at Arizona State

The purpose of this study was to evaluate how COVID-19 has affected college athletes physically and mentally. A survey with 36 questions encompassing gender, sport, COVID-19 symptom severity, type and duration, return to play factors, perceived social isolation, depression and anxiety was distributed to all student athletes at Arizona State University. A total of 26 athletes (84.6% female, 15.4% male) who previously contracted the COVID-19 virus participated in the survey, representing a variety of 12 different sports. The study concluded that as student athletes symptom severity increased, symptom duration increased as well. Between one day to 10 months of continued symptoms after returning to sport play was reported by one-third of participating student athletes; however, there was no indication that vaccination status, obtaining a negative COVID-19 test, or obtaining medical clearance prior to returning to sport play after contracting COVID-19 affected if symptoms persisted or not after returning to play. Most (92.3%) athletes reported higher levels of perceived isolation, and as social isolation scores increased, depression scores increased. Abnormal anxiety symptoms were reported by 30.8% of student athletes, and as depression scores increased, anxiety scores increased as well. Study results and further research can be utilized to improve and refine gradual return to play protocols, enhance methods of communication and integration during mass social isolation, and greater assess depression and anxiety prevalence in student athletes.

ContributorsHanley, Breanna (Author) / Larson, David (Thesis director) / Ross, Allison (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor)
Created2022-05
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Description
This was a mixed methods project investigating the effects of remote learning and COVID-19 on ASU students. This study was performed during the transition from remote learning back to in-person learning. It is a holistic view of the university experience and analyzes student's ideas and opinions on how that university

This was a mixed methods project investigating the effects of remote learning and COVID-19 on ASU students. This study was performed during the transition from remote learning back to in-person learning. It is a holistic view of the university experience and analyzes student's ideas and opinions on how that university experience shifted during remote learning and their return to campus. The study utilizes both statistical analysis of quantitative data and a thematic analysis of student responses. This project also included a video interview, where students and one faculty member were filmed in order to give better insight into how individuals were affected. Video Link: https://youtu.be/E0bY4-WC8X0
ContributorsKageyama, Vincent (Author) / Altobelli, Ian (Co-author) / Han, Yooro (Co-author) / Garcia Ayon, Yanik (Co-author) / Penkrot, Tonya (Thesis director) / Kizer, Elizabeth (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor)
Created2022-05
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Description

The following study was designed to better understand the perceived stress levels and common coping strategies of nursing students attending Arizona State University during the COVID-19 pandemic. Lazarus and Folkman’s (1984) transactional theory of stress and coping suggests that stress is a product of the transaction between an individual and

The following study was designed to better understand the perceived stress levels and common coping strategies of nursing students attending Arizona State University during the COVID-19 pandemic. Lazarus and Folkman’s (1984) transactional theory of stress and coping suggests that stress is a product of the transaction between an individual and their complex environment. During the COVID-19 pandemic nursing students were forced to close and utilize online learning methods to ensure the safety of students, faculty, and staff. The current study identifies the perceived stress levels and common coping strategies of undergraduate nursing students at Arizona State University. A survey was sent to the identified population which asked participants to rate their stress level of attending nursing school during COVID-19 on a scale from one to ten. In addition, the Carver’s COPE inventory was utilized to determine common coping strategies among the nursing student population. The results of this study indicate that the closure of universities, and utilization of online learning methods increased stress levels of nursing students attending Arizona State University during COVID-19. In addition, nursing students most common coping strategies were identified as the use of planning, a problem-focused coping strategy, reinterpretation and growth, and active coping.

ContributorsBillera, Ava (Author) / Savaglio, Lauren (Thesis director) / Sebren, Ann (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor)
Created2022-05
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Description

The COVID-19 pandemic has led to high demand for testing. It also has affected minorities at disproportionate rates, and the impact is made worse due to the underlying mistrust minorities hold against medical institutions. A similar theme is observed against physicians, especially Asian American healthcare providers experiencing firsthand discrimination. Therefore,

The COVID-19 pandemic has led to high demand for testing. It also has affected minorities at disproportionate rates, and the impact is made worse due to the underlying mistrust minorities hold against medical institutions. A similar theme is observed against physicians, especially Asian American healthcare providers experiencing firsthand discrimination. Therefore, there is this reciprocal relationship between the patient and provider rooted in mistrust and discriminatory biases. This thesis aims to analyze how ASU Biodesign COVID-19 Testing Lab (ABCTL) functions to implicitly modify potential effects of a patient-provider relationship based on the concepts of health equity and cultural humility. The analysis then suggests that ABCTL accomplished the concept of health equity through community partnerships and by recruiting community healthcare workers for long-term stability, it successfully achieved cultural humility.

ContributorsCalo, Van Dexter (Author) / Compton, Carolyn (Thesis director) / Cheong, Pauline (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor)
Created2022-05
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Description
This was a mixed methods project investigating the effects of remote learning and COVID-19 on ASU students. This study was performed during the transition from remote learning back to in-person learning. It is a holistic view of the university experience and analyzes student's ideas and opinions on how that university

This was a mixed methods project investigating the effects of remote learning and COVID-19 on ASU students. This study was performed during the transition from remote learning back to in-person learning. It is a holistic view of the university experience and analyzes student's ideas and opinions on how that university experience shifted during remote learning and their return to campus. The study utilizes both statistical analysis of quantitative data and a thematic analysis of student responses. This project also included a video interview, where students and one faculty member were filmed in order to give better insight into how individuals were affected. Video Link: https://youtu.be/E0bY4-WC8X0
ContributorsHan, Yooro (Author) / Altobeli, Ian (Co-author) / Garcia Ayon, Yanik (Co-author) / Kageyama , Vincent (Co-author) / Penkrot, Tonya (Thesis director) / Kizer, Elizabeth (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor)
Created2022-05