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- All Subjects: COVID-19
- Creators: Barrett, The Honors College
coronavirus 2 (SARS-CoV-2), has been responsible for significant social and economic
disruption, prompting an urgent search for therapeutic solutions. The spike protein of the virus
has been examined as an immunogenic target because of its role in viral binding and fusion
necessary for infection of host cells. Previous studies have identified a recombinant protein
(denoted as S1) that has been shown to potentially induce a neutralizing antibody response by
mimicking the structure of the SARS-CoV-2 spike protein. We have produced the S1 in plants
using agroinfiltration, a plant transformation technique whereby plasmid-containing
Agrobacterium tumefaciens is injected into Nicotiana benthamiana plants, resulting in transfer of
the desired gene from bacteria to plant cells. S1 was expressed to high levels within 5 days of
infiltration, and Western blot analysis showed recognition of the S1 by an anti-S1 antibody.
ELISA results exhibited increased binding activity to anti-S1 with increasing concentrations of
S1, indicating their specific interaction. This ongoing study will demonstrate the potential of a
plant-produced S1 as a vaccine, therapeutic, and diagnostic tool against COVID-19 that is not
only effective, but also cost-efficient and scalable in comparison to conventional mammalian cell
culture production methods.
An exploration into the history of the 1918 Influenza Pandemic and the societal impacts associated with it, as well as an analysis of the developing SARS-CoV-2 pandemic today. Based upon these analyses, similarities were drawn between the two pandemics which suggested a lack of innovation in preventative measures over the last century. Given this conclusion a series of proposals were made that should be further explored to give not only the United States, but the world at large, a better chance in the face of the next emerging disease.
Spring of 2020 and the COVID-19 pandemic brought significant challenges and life changes for people around the world. The sudden isolation, the health-related anxiety, and the drastic changes in daily routines affected everyone. This study measures the impact COVID-19 had on incoming first-year students at Arizona State University, and how the pandemic impacted their mental health. A total of 92 students participated in this study and were recruited through convenience sampling. In order to gain a better understanding of how students were truly doing transitioning into college during the pandemic, both quantitative and qualitative data were collected in the forms of a survey and optional follow-up interviews. Congruent with previous literature, the survey found that the COVID-19 pandemic had a negative impact on college students and their mental health. Seven students completed the follow-up interviews and expanded on their answers in the survey through personal examples of their first-year experiences. After the survey and follow-up interviews were completed, I presented my findings for first-year students in Mary Lou Fulton Teacher’s College to help students see that they were not alone. This research allowed students the opportunity to be heard and share their experiences, as well as, to obtain access to resources that promote their mental health and academic success during the challenging time.
This scoping review provides a synthesis of research which maps the literature on the topic of COVID-19 related impact on Undergraduate Student Mental Health and Baccalaureate Success. The purpose of this review was to identify existing literature pertaining to the psychological repercussions of COVID-19 on the undergraduate population, describe the range of successful interventions used to reduce stress and demand on the U.S. undergraduate population during a pandemic, and identify implications for future research. Due to the novelty of coronavirus and limited research on the given topic, this review provides a framework of available research by identifying types of available research, identifying how research is conducted on the topic, identifying and analyzing knowledge gaps, and clarifies key concepts in literature.
Archival data for 32 countries were collected and a bivariate correlational analysis was run to determine any correlations between the predictors (tightness and individualism) and predicted variables (health outcomes and social behaviors).
This project was a long form article talking about the struggles the competitive fighting game community had with poor online multiplayer during the pandemic and how rollback netcode aims to remedy that problem as well as provide easy online play for everyone.