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While there is extensive information available about organizations that receive donated organs for transplant, much less is known about those that accept tissue and whole bodies for medical education and research. Throughout the United States, nontransplant anatomical donation organizations exist within an ambiguous sector of the donation industry, unencumbered by federal regulations. Although these companies adhere to the Uniform Anatomical Gift Act, the lack of a single entity responsible for overseeing their operations has led to public skepticism and animosity among competing businesses. Legislation has the potential to legitimize the industry. For it to be successful, however, the intricacies of a complex market that deals directly with the movement of human remains and intangible issues of human integrity and morality, must be thoroughly understood.
ContributorsGlynn, Emily Sanders (Author) / Brian, Jennifer (Thesis director) / Fisher, Rebecca (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor) / Department of English (Contributor)
Created2015-05
Description
Chemoreception is an important method for an octopus to sense and react to its surroundings. However, the density of chemoreceptors within different areas of the skin of the octopus arm is poorly documented. In order to assess the relative sensitivity of various regions and the degree to which chemoreception is locally controlled, octopus arms were amputated and exposed to acetic acid, a noxious chemical stimulus that has previously been shown to elicit movement responses in amputated arms (Hague et al., 2013). To test this, 11 wild-caught Octopus bimaculoides (6 females, 5 males) were obtained. Acetic acid vapor was introduced in the distal oral, distal aboral, proximal oral, and proximal aboral regions of amputated arms. The frequency of the occurrence of movement was first analyzed. For those trials in which movement occurred, the latency (delay between the stimulus and the onset of movement) and the duration of movement were analyzed. The distal aboral and distal oral regions were both more likely to move than either the proximal oral or proximal aboral regions (p < 0.0001), and when they did move, were more likely to move for longer periods of time (p < 0.05). In addition, the proximal oral region was more likely to exhibit a delay in the onset of movement compared to the distal oral or distal aboral regions (p < 0.0001). These findings provide evidence that the distal arm is most sensitive to noxious chemical stimuli. However, there were no significant differences between the distal oral and distal aboral regions, or between the proximal oral and proximal aboral regions. This suggests that there may not be a significant difference in the density of chemoreceptors in the aboral versus oral regions of the arm, contrary to claims in the literature. The other independent variables analyzed, including sex, body mass, arm length, anterior versus posterior arm identity, and left versus right arm identity, did not have a significant effect on any of the three dependent variables analyzed. Further analysis of the relative density of chemoreceptors in different regions of the octopus arm is merited.
ContributorsCasleton, Rachel Marie (Author) / Fisher, Rebecca (Thesis director) / Marvi, Hamidreza (Committee member) / Gire, David (Committee member) / School of International Letters and Cultures (Contributor) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05