Matching Items (4)
- All Subjects: Cancer
- Creators: Foy, Joseph
- Member of: Barrett, The Honors College Thesis/Creative Project Collection
Mr. Green has stage 4 prostate cancer which has spread to the bones and liver and has become resistant to radiation and standard chemotherapy treatment. After 3 rounds of chemotherapy, his primary oncologist recommends that he participate in a clinical trial. He went to Dr. Red at the Saguaro Clinic after reading on the internet about a new Phase 1 clinical trial that the clinic is hosting, which is designed to target a specific receptor called AB-111 that may be present in malignant prostate, cervical, ovarian, and breast cells. After signing consent and completing the blood screens in the morning at the clinic, Mr. Green is told his liver enzymes are too high and the ranges specified in the protocol prohibit him from enrolling. Mr. Green is noticeably affected and distressed at this news, and Dr. Red recommends end-of-life care. Behind the scenes, this event is noted on official medical documents and trial study rosters as a "screen fail." This narrative, while fictional, is realistic because similar events occur in cancer clinical trial sites on a regular basis. I look at the inner "world" and mental journey of possible clinical trial candidates as they seek out information about clinical trials and gain understanding of their function \u2014 specifically in the context of Phase 1 cancer clinical trials. To whom is the language of the term "screen failure" useful? How does excluding individuals from clinical trials protect their health and does the integrity of the trial data supersede the person's curative goals? What is the message that cancer patients (potential research subjects) receive regarding clinical trials from sources outside their oncologists?
My mother died after a long battle with breast cancer in 2008. I was only nine when she was first diagnosed, and so much of my life has been shaped by her struggle for survival. She will always be the most amazing women I have ever known, and she taught me more about life, kindness, hope, and overcoming the odds than anyone else. I want to share my experience with you as a friend \u2014 not as a doctor, or a counselor, but as a friend. I want to tell you some of my stories with the emotions behind them. I will share how I learned t cope with whatever situation came our way and how I found unexpected ways to help my mom. I want you to find solace through our shared emotions even if they are at different times in our journeys. This is why in the following chapters, my stories are not chronological but categorized through the major emotions that drove my stories. I hope this book can help those who find themselves in similar situations to the one I found myself in when my mom picked me up from fourth grade with a bandana on her head instead of her normal, beautiful brown hair. This thesis is a creative exploration of emotions and finding hope in times of great loss.
ROB ROY AND THE EXPLORATION OF CULTURAL IDENTITY: THE SOCIOPOLITICAL RELATIONSHIP OF ENGLAND AND SCOTLAND ACCORDING TO SIR WALTER SCOTT
The interaction between England and Scotland is complicated and continually changing. Scottish writer Sir Walter Scott examines this long-standing relationship through his various writings. Scott conveys a presence that is both acutely aware of the damages enacted upon Scotland by various English political efforts, and sensitive to the delicate relationship that the two regions had begun to form during his lifetime. Through a critical analysis of Scott's novel, Rob Roy, one can see the various strategies Scott used to balance the need to address prior controversies within the relationship, and the petition to move beyond the prior conflict and develop a mutual understanding of each culture. Through this, Scott is able to regenerate a sense of Scottish nationalism for his people, and encourage improved relations within the British Isles.
This paper examines the physics behind cancer treatment and more specifically radiation therapy. A phenomenon known as Compton scattering has played a substantial role in the treatment of breast cancer and improvement of lives of women around the world. Through Compton scattering, radiation therapy has been tremendously improved and has allowed for the most accurate and effective treatment in breast cancer patients today.