Matching Items (318)
Filtering by

Clear all filters

133382-Thumbnail Image.png
Description
This paper explores how changing the color of chocolate can affect its perceived taste. While color psychology and its effects on food industry marketing are widely studied, this experiment focuses on blue, red, green, and purple striped chocolates. The study conducted for this paper focuses on these four colors based

This paper explores how changing the color of chocolate can affect its perceived taste. While color psychology and its effects on food industry marketing are widely studied, this experiment focuses on blue, red, green, and purple striped chocolates. The study conducted for this paper focuses on these four colors based on their utilization in previously conducted experiments. Each color of chocolate involved 25 participants, for a total of 100 total individuals, who each taste tested one piece and immediately filled out a survey. The survey asked demographic questions, colored chocolate preferences, and questions ranking the chocolate's appeal. While the outcome showed that blue, green, red, and purple was indeed the order of appealing colors, the study results indicate the participants' color preferences did not affect their perceived taste of the chocolate they sampled. Rather, their preference was based on experiences they associated with the color of the chocolate they tasted.
ContributorsChan, Sydney (Author) / Gray, Nancy (Thesis director) / Giard, Jacques (Committee member) / Barrett, The Honors College (Contributor)
Created2018-05
131538-Thumbnail Image.png
Description
The purpose of this project is to raise awareness for children with social anxiety. As a book directed to children around the age of 12, it will give them a character they can relate to, so they can feel less alone. Throughout the story, the main character experiences symptoms of

The purpose of this project is to raise awareness for children with social anxiety. As a book directed to children around the age of 12, it will give them a character they can relate to, so they can feel less alone. Throughout the story, the main character experiences symptoms of social anxiety and is subject to events that exacerbate those symptoms. Despite her challenges, the main character is able to effectively cope with her social anxiety through her own hard work, and help from her family members, teachers, and peers. The intent is to show children with social anxiety that, contrary to what their disorder makes them feel, they are special and have the capacity to develop skills that are relevant to their talents and interests, and overcome their fears. They should know that parents, teachers, and peers will be there to help and support them and will not judge them as harshly as they suspect. The supporting characters in this story show how a strong support base can influence the success of children with social anxiety. By the end of the story, the main character still has social anxiety, but has gained confidence and her symptoms are less severe. This illustrates that, although social anxiety cannot simply be overcome—that is, it doesn’t go away completely—it can be effectively managed with assistance from close others, and perseverance.
ContributorsDillard, Bethlehem (Author) / Lewis, Stephen (Thesis director) / Gaffney, Cynthia (Committee member) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
133891-Thumbnail Image.png
Description
The current study investigated whether intermittent restraint stress (IRS) would impair fear extinction learning and lead to increased anxiety and depressive- like behaviors and then be attenuated when IRS ends and a post- stress rest period ensues for 6 weeks. Young adult, male Sprague Dawley rats underwent restraint stress using

The current study investigated whether intermittent restraint stress (IRS) would impair fear extinction learning and lead to increased anxiety and depressive- like behaviors and then be attenuated when IRS ends and a post- stress rest period ensues for 6 weeks. Young adult, male Sprague Dawley rats underwent restraint stress using wire mesh (6hr/daily) for five days with two days off before restraint resumed for three weeks for a total of 23 restraint days. The groups consisted of control (CON) with no restraint other than food and water restriction yoked to the restrained groups, stress immediate (STR-IMM), which were restrained then fear conditioned soon after the end of the IRS paradigm, and stress given a rest for 6 weeks before fear conditioning commenced (STR-R6). Rats were fear conditioned by pairing a 20 second tone with a footshock, then given extinction training for two days (15 tone only on each day). On the first day of extinction, all groups discriminated well on the first trial, but then as trials progressed, STR-R6 discriminated between tone and context less than did CON. On the second day of extinction, STR- IMM froze more to context in the earlier trials than compared to STR-R6 and CON. As trials progressed STR-IMM and STR-R6 froze more to context than compared to CON. Together, CON discriminated between tone and context better than did STR-IMM and STR-R6. Sucrose preference, novelty suppressed feeding, and elevated plus maze was performed after fear extinction was completed. No statistical differences were observed among groups for sucrose preference or novelty suppressed feeding. For the elevated plus maze, STR-IMM entered the open arms and the sum of both open and closed arms fewer than did STR- R6 and CON. We interpret the findings to suggest that the stress groups displayed increased hypervigilance and anxiety with STR-R6 exhibiting a unique phenotype than that of STR-IMM and CON.
ContributorsShah, Vrishti Bimal (Author) / Conrad, Cheryl (Thesis director) / Newbern, Jason (Committee member) / Judd, Jessica (Committee member) / School of Life Sciences (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
134152-Thumbnail Image.png
Description
Due to artificial selection, dogs have high levels of phenotypic diversity, yet, there appears to be low genetic diversity within individual breeds. Through their domestication from wolves, dogs have gone through a series of population bottlenecks, which has resulted in a reduction in genetic diversity, with a large amount of

Due to artificial selection, dogs have high levels of phenotypic diversity, yet, there appears to be low genetic diversity within individual breeds. Through their domestication from wolves, dogs have gone through a series of population bottlenecks, which has resulted in a reduction in genetic diversity, with a large amount of linkage disequilibrium and the persistence of deleterious mutations. This has led to an increased susceptibility to a multitude of diseases, including cancer. To study the effects of artificial selection and life history characteristics on the risk of cancer mortality, we collected cancer mortality data from four studies as well as the percent of heterozygosity, body size, lifespan and breed group for 201 dog breeds. We also collected specific types of cancer breeds were susceptible to and compared the dog cancer mortality patterns to the patterns observed in other mammals. We found a relationship between cancer mortality rate and heterozygosity, body size, lifespan as well as breed group. Higher levels of heterozygosity were also associated with longer lifespan. These results indicate larger breeds, such as Irish Water Spaniels, Flat-coated Retrievers and Bernese Mountain Dogs, are more susceptible to cancer, with lower heterozygosity and lifespan. These breeds are also more susceptible to sarcomas, as opposed to carcinomas in smaller breeds, such as Miniature Pinschers, Chihuahuas, and Pekingese. Other mammals show that larger and long-lived animals have decreased cancer mortality, however, within dog breeds, the opposite relationship is observed. These relationships could be due to the trade-off between cellular maintenance and growing fast and large, with higher expression of growth factors, such as IGF-1. This study further demonstrates the relationships between cancer mortality, heterozygosity, and life history traits and exhibits dogs as an important model organism for understanding the relationship between genetics and health.
ContributorsBalsley, Cassandra Sierra (Author) / Maley, Carlo (Thesis director) / Wynne, Clive (Committee member) / Tollis, Marc (Committee member) / School of Life Sciences (Contributor) / School of Human Evolution and Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2017-12
134170-Thumbnail Image.png
Description
The purpose of this study was to examine whether positive affirmations can lower depressive symptoms amongst male and female Arizona State University (ASU) honors students. Male and female ASU honors students (20-22 years of age; N=40) were recruited from Barrett, the Honors College, through email and online newsletters. Students who

The purpose of this study was to examine whether positive affirmations can lower depressive symptoms amongst male and female Arizona State University (ASU) honors students. Male and female ASU honors students (20-22 years of age; N=40) were recruited from Barrett, the Honors College, through email and online newsletters. Students who had been previously or were at the time diagnosed with clinical depression were not permitted to participate in the study. Only 9 female and 14 males completed the entire study. Participants completed a pre- and post- test that each consisting of reading aloud questions and their answers from the Beck's Depression Inventory (BDI) while being video and audio recorded. Participants were given a list of 20 affirmations after the pre-test and were instructed to choose and read to themselves a new affirmation three times a day, 3 times a week for a total of 6 weeks. There was an average increase among all participants' BDI scores, but no significance was found in the improvement. Emotional responses were captured using the facial recognition software, Noldus FaceReader, and was used to observe whether there was emotional dissonance in the BDI answers. The correlation between the emotion "sad" and the answer chosen was found by using Pearson's r for each participants. There were only 2 total interviews that indicated a strong positive correlation and 1 interview that indicated strong negative correlation. All others were either moderate or minimal correlation, showing that the majority of participants' emotions may have not affected their answer choices. Results indicated there is no significant improvement when using affirmations to improve depressive symptoms and mood.
ContributorsChan, Angie (Co-author) / Duran, Jose (Co-author) / Chisum, Jack (Thesis director) / Hrncir, Micki (Committee member) / Barrett, The Honors College (Contributor)
Created2017-05
135570-Thumbnail Image.png
Description
There is a disconnect between the way people are taught to find success and happiness, and the results observed. Society teaches us that success will lead to happiness. Instead, it is argued that success is engrained in happiness. Case studies of four, established, successful people: Jack Ma, Elon Musk, Ricardo

There is a disconnect between the way people are taught to find success and happiness, and the results observed. Society teaches us that success will lead to happiness. Instead, it is argued that success is engrained in happiness. Case studies of four, established, successful people: Jack Ma, Elon Musk, Ricardo Semler, and William Gore, have been conducted in order to observe an apparent pattern. This data, coupled with the data from Michael Boehringer's story, is used to formulate a solution to the proposed problem. Each case study is designed to observe characteristics of the individuals that allow them to be successful and exhibit traits of happiness. Happiness will be analyzed in terms of passion and desire to perform consistently. Someone who does what they love, paired with the ability to perform on a regular basis, is considered to be a happy person. The data indicates that there is an observable pattern within the results. From this pattern, certain traits have been highlighted and used to formulate guidelines that will aid someone falling short of success and happiness in their lives. The results indicate that there are simple questions that can guide people to a happier life. Three basic questions are defined: is it something you love, can you see yourself doing this every day and does it add value? If someone can answer yes to all three requirements, the person will be able to find happiness, with success following. These guidelines can be taken and applied to those struggling with unhappiness and failure. By creating such a formula, the youth can be taught a new way of thinking that will help to eliminate these issues, that many people are facing.
ContributorsBoehringer, Michael Alexander (Author) / Kashiwagi, Dean (Thesis director) / Kashiwagi, Jacob (Committee member) / Department of Management (Contributor) / School of Mathematical and Statistical Sciences (Contributor) / Department of Finance (Contributor) / Sandra Day O'Connor College of Law (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
135584-Thumbnail Image.png
Description
Breast cancer is the leading cause of cancer-related deaths of women in the united states. Traditionally, Breast cancer is predominantly treated by a combination of surgery, chemotherapy, and radiation therapy. However, due to the significant negative side effects associated with these traditional treatments, there has been substantial efforts to develo

Breast cancer is the leading cause of cancer-related deaths of women in the united states. Traditionally, Breast cancer is predominantly treated by a combination of surgery, chemotherapy, and radiation therapy. However, due to the significant negative side effects associated with these traditional treatments, there has been substantial efforts to develop alternative therapies to treat cancer. One such alternative therapy is a peptide-based therapeutic cancer vaccine. Therapeutic cancer vaccines enhance an individual's immune response to a specific tumor. They are capable of doing this through artificial activation of tumor specific CTLs (Cytotoxic T Lymphocytes). However, in order to artificially activate tumor specific CTLs, a patient must be treated with immunogenic epitopes derived from their specific cancer type. We have identified that the tumor associated antigen, TPD52, is an ideal target for a therapeutic cancer vaccine. This designation was due to the overexpression of TPD52 in a variety of different cancer types. In order to start the development of a therapeutic cancer vaccine for TPD52-related cancers, we have devised a two-step strategy. First, we plan to create a list of potential TPD52 epitopes by using epitope binding and processing prediction tools. Second, we plan to attempt to experimentally identify MHC class I TPD52 epitopes in vitro. We identified 942 potential 9 and 10 amino acid epitopes for the HLAs A1, A2, A3, A11, A24, B07, B27, B35, B44. These epitopes were predicted by using a combination of 3 binding prediction tools and 2 processing prediction tools. From these 942 potential epitopes, we selected the top 50 epitopes ranked by a combination of binding and processing scores. Due to the promiscuity of some predicted epitopes for multiple HLAs, we ordered 38 synthetic epitopes from the list of the top 50 epitope. We also performed a frequency analysis of the TPD52 protein sequence and identified 3 high volume regions of high epitope production. After the epitope predictions were completed, we proceeded to attempt to experimentally detected presented TPD52 epitopes. First, we successful transduced parental K562 cells with TPD52. After transduction, we started the optimization process for the immunoprecipitation protocol. The optimization of the immunoprecipitation protocol proved to be more difficult than originally believed and was the main reason that we were unable to progress past the transduction of the parental cells. However, we believe that we have identified the issues and will be able to complete the experiment in the coming months.
ContributorsWilson, Eric Andrew (Author) / Anderson, Karen (Thesis director) / Borges, Chad (Committee member) / School of Molecular Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
135193-Thumbnail Image.png
Description
This purpose of this thesis study was to examine variables of the "War on Cancer" frame, loss-gain prime, and patient gender on treatment decision for advanced cancer patients. A total of 291 participants (141 females) participated in an online survey experiment and were randomly assigned to one of eight possible

This purpose of this thesis study was to examine variables of the "War on Cancer" frame, loss-gain prime, and patient gender on treatment decision for advanced cancer patients. A total of 291 participants (141 females) participated in an online survey experiment and were randomly assigned to one of eight possible conditions, each of which were comprised of a combination of one of two levels for three total independent variables: war frame ("War on Cancer" frame or neutral frame), loss-gain prime (loss prime or gain prime), and patient gender (female or male). Each of the three variables were operationalized to determine whether or not the exposure to the war on cancer paradigm, loss-frame language, or male patient gender would increase the likelihood of a participant choosing a more aggressive cancer treatment. Participants read a patient scenario and were asked to respond to questions related to motivating factors. Participants were then asked to report preference for one of two treatment decisions. Participants were then asked to provide brief demographic information in addition to responding to questions about military history, war attitudes, and cancer history. The aforementioned manipulations sought to determine whether exposure to various factors would make a substantive difference in final treatment decision. Contrary to the predicted results, participants in the war frame condition (M = 3.85, SD = 1.48) were more likely to choose the pursuit of palliative care (as opposed to aggressive treatment) than participants in the neutral frame condition (M = 3.54, SD = 1.23). Ultimately, these significant findings suggest that there is practical information to be gained from treatment presentation manipulations. By arming healthcare providers with a more pointed understanding of the nuances of treatment presentation, we can hope to empower patients, their loved ones, and healthcare providers entrenched in the world of cancer treatment.
ContributorsKnowles, Madelyn Ann (Author) / Kwan, Virginia S. Y. (Thesis director) / Presson, Clark (Committee member) / Salamone, Damien (Committee member) / Department of Psychology (Contributor) / School of Human Evolution and Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
Today, successful design is not only pleasing to the eye but may also help to manage social behaviors which can lead to increased satisfaction and increased revenue for clients. Designers function as problem solvers to provide solutions to challenges certain spaces face promoting or driving desired human interaction through effective

Today, successful design is not only pleasing to the eye but may also help to manage social behaviors which can lead to increased satisfaction and increased revenue for clients. Designers function as problem solvers to provide solutions to challenges certain spaces face promoting or driving desired human interaction through effective design of the built environment. The experience-based economy of the 21st century prompts companies to attempt to stage an experience by connecting on a personal level with consumers in order to create value and support consumer needs. In experience-based design, interior design embraces social psychology by structuring the built environment to function as a tool to manage social interactions. Due to the nature of the human animal, social interactions in turn alter the culture of a specific place in an iterative process. Through this dynamic relationship, interior design can seek to either support the culture or function of a place and its users or work to effect change.
ContributorsMarcolla, Patrice Marie (Author) / Bernardi, Jose (Thesis director) / Bochart, Sonja (Committee member) / W. P. Carey School of Business (Contributor) / The Design School (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
134288-Thumbnail Image.png
Description
Introduction: The current study aimed to explore the prevalence rates of binge-eating and weight compensatory behaviors across sexual minority undergraduate men and women. Methods: The sample included 3411 undergraduate men and women from a large public university. Participants completed a self-report online questionnaire regarding various personality, social networking, and health

Introduction: The current study aimed to explore the prevalence rates of binge-eating and weight compensatory behaviors across sexual minority undergraduate men and women. Methods: The sample included 3411 undergraduate men and women from a large public university. Participants completed a self-report online questionnaire regarding various personality, social networking, and health behaviors. Results: Analyses showed no difference in binge-eating for women, but statistically significant differences across sexual orientation groups for weight compensatory behaviors. Analyses for men showed statistically significant differences between sexual orientation groups for objective-binge eating and self-induced vomiting. There were no differences among men for other behaviors. Discussion: These findings demonstrate both statistically and clinically significant differences across sexual orientation groups indicating that gender as well as sexual orientation bear a correlation to the propensity to engage in certain disordered eating behaviors.
ContributorsVon Schell, Anna Victoria (Author) / Perez, Marisol (Thesis director) / Ohrt, Tara (Committee member) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05