Matching Items (23)
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- All Subjects: Exercise
- All Subjects: Diabetes
- Creators: College of Health Solutions
Description
This study examines the effect of exercise therapy on a stationary bike on cognitive function, specifically inhibition and set-switching, in adolescents with Down syndrome. 44 participants were randomly divided between the voluntary cycling therapy group (VCT) (i.e., self-selected cadence), assisted cycling therapy group (ACT) (i.e., 30% faster than self-selected cadence accomplished by a motor), and a control group (NC) in which the participants did not undergo any exercise therapy. Both cycling groups rode a stationary bicycle, for 30 minutes, three times a week, for eight-weeks. At the beginning (i.e., pretest) and end (i.e., posttest) of the eight-week session the participants completed tasks to evaluate their cognitive function. They completed three trials of the card sort test (i.e., set-switching) and three trials of the knock-tap test (i.e, inhibition) before and after eight-weeks of cycling therapy. The scores of these tests were analyzed using one-way ANOVA between groups and paired samples t-tests. The results showed that after eight-weeks of cycling therapy the participants in the VCT group performed worse in the knock-tap test, but improved in two trials of the card sort test. The results also showed that the participants in the ACT group performed worse after eight-weeks of exercise therapy in one trial of the card sort test. No significant changes were seen for the control group. Due to the fact that on average the participants in the VCT group cycled with a higher heart rate, our results suggest exercise that significantly elevates heart rate can improve cognitive function, specifically set-switching, in adolescents with Down syndrome.
ContributorsBenson, Alicia Meigh (Author) / Ringenbach, Shannon (Thesis director) / Amazeen, Eric (Committee member) / Maraj, Brian (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2015-05
Description
About 75% of men and 66.58% of women are considered overweight or obese (BMI ≥25). $117 billion dollars is spent each year in medical costs due to physical inactivity. Aerobic exercise has been well defined in its’ benefits to cardiovascular health; however, the effects of resistance training are still not well defined. The purpose of this preliminary analysis was to evaluate the vascular health effects (central and peripheral blood pressure and VO2 max) of two different types of resistance training programs: high load, low repetitions resistance training and low load, high repetitions resistance training. Fourteen participants aged 18-55 years (6 males, 8 females) were involved in this preliminary analysis. Data were collected before and after the 12-week long exercise program (36 training sessions) via pulse wave analysis and VO2peak testing. Multivariate regression analysis of training program effects, while adjusting for body mass index and time, did not result in significant training effects on central and peripheral diastolic blood pressure, nor VO2peak. A statistical trend was observed between the different training programs for systolic blood pressure, suggesting that subjects partaking in the high load, low repetitions program exhibited higher systolic blood pressures than the low load, high repetitions group. With a larger sample size, the difference in systolic blood pressure may increase between training program groups and indicate that greater loads with minimal repetitions may increase lead to clinically significant elevations in blood pressure. Further work is needed to uncover the relationship between different types of resistance training and blood pressure, especially if these lifting regimens are continued for longer lengths of time.
ContributorsHill, Cody Alan (Co-author) / Hill, Cody (Co-author) / Whisner, Corrie (Thesis director) / Angadi, Siddhartha (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Background and Purpose— There is limited conclusive data on both pharmacological and holistic treatment options to improve cognition in adults after stroke. In particular, there is lacking evidence for cognitive rehabilitation in the subacute and chronic phases when cognitive impairment may be more perceptible. In this meta-analytic review, our primary objective was to determine the cognitive effects of aerobic exercise on post-stroke adults in the post-acute phases. Secondary objectives were to investigate the differential effects of aerobic exercise on sub-domains of cognitive function.
Methods— Data were extracted and filtered from electronic databases PubMed (MEDLINE), CINAHL, Embase, PsycINFO, and Scopus. Intervention effects were represented by Hedges’ g and combined into pooled effect sizes using random effects models. Heterogeneity was evaluated using the Chi-squared (Q) and I-squared statistics.
Results— Five studies met inclusion criteria, representing data from 182 participants. The primary analysis produced a positive overall effect of aerobic exercise on cognitive performance (Hedges’ g [95% confidence interval]= 0.42 [0.007–0.77]). Effects were significantly different from zero for aerobic interventions combined with other physical activity interventions (Hedges’ g [CI] =0.59 [0.26 to 0.92]), but not for aerobic interventions alone (P= 0.40). In specific subdomains, positive moderate effects were found for global cognitive function (Hedges’ g [CI] =0.79 [0.31 to 1.26]) but not for attention and processing speed (P=0.08), executive function (P= 0.84), and working memory (P=0.92).
Conclusions— We determined that aerobic exercise combined with other modes of training produced a significant positive effect on cognition in adults after stroke in the subacute and chronic phases. Our analysis supports the use of combined training as a treatment option to enhance long-term cognitive function in adults after stroke. Further research is needed to determine the efficacy of aerobic training alone.
Methods— Data were extracted and filtered from electronic databases PubMed (MEDLINE), CINAHL, Embase, PsycINFO, and Scopus. Intervention effects were represented by Hedges’ g and combined into pooled effect sizes using random effects models. Heterogeneity was evaluated using the Chi-squared (Q) and I-squared statistics.
Results— Five studies met inclusion criteria, representing data from 182 participants. The primary analysis produced a positive overall effect of aerobic exercise on cognitive performance (Hedges’ g [95% confidence interval]= 0.42 [0.007–0.77]). Effects were significantly different from zero for aerobic interventions combined with other physical activity interventions (Hedges’ g [CI] =0.59 [0.26 to 0.92]), but not for aerobic interventions alone (P= 0.40). In specific subdomains, positive moderate effects were found for global cognitive function (Hedges’ g [CI] =0.79 [0.31 to 1.26]) but not for attention and processing speed (P=0.08), executive function (P= 0.84), and working memory (P=0.92).
Conclusions— We determined that aerobic exercise combined with other modes of training produced a significant positive effect on cognition in adults after stroke in the subacute and chronic phases. Our analysis supports the use of combined training as a treatment option to enhance long-term cognitive function in adults after stroke. Further research is needed to determine the efficacy of aerobic training alone.
ContributorsMitchell, Michaela (Author) / Holzapfel, Simon (Thesis director) / Bosch, Pamela (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Chronic diseases place a financial burden on the United States and claim the lives of nearly 2 million Americans every year. Among the chronic diseases that plague American people, type 2 diabetes is particularly prevalent and injurious. Thus, action is warranted to improve prevention and management of this disease. Nutrition plays a significant role in prevention and management of type 2 diabetes and other chronic diseases. Registered dietitians, as nutrition experts, are qualified to use medical nutrition therapy as a method of prevention and treatment for chronic diseases using a nutritional approach. However, there is no consensus as to which eating pattern is the most efficacious. The aim of this review of research was to examine how plant-based eating patterns impact chronic disease conditions, with an emphasis on type 2 diabetes mellitus, as compared to omnivorous eating patterns. A literature search was conducted through the ASU Library, PubMed, and CINAHL using terms related to plant-based diets and chronic diseases, such as type 2 diabetes. The results revealed that a plant-based eating pattern may be beneficial in the prevention and treatment of certain chronic diseases, such as type 2 diabetes. Specifically, adults who have type 2 diabetes and consume a plant-based diet may exhibit enhanced glycemic control as evidenced by less insulin resistance, increased incretin and insulin secretion, greater insulin sensitivity, and improved HbA1c levels. There is sufficient evidence for registered dietitians to recommend a plant-based approach to patients with type 2 diabetes who would like to achieve enhanced glycemic control.
ContributorsSneddon, Ashley (Author) / Mayol-Kreiser, Sandra (Thesis director) / Shepard, Christina (Committee member) / College of Health Solutions (Contributor, Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
The purpose of this study was to examine the validity of a modified Assisted Cycling Therapy bicycle for improving depression in children with Down Syndrome (DS). Seven participants completed 2x/week for 8 weeks, 30 minutes at a time of ACT, in which participants’ voluntary pedaling rates were augmented via the bicycle motor, ensuring that they were pedaling at a rate greater than their self-paced rate. Depression was measured using a modified version of the Children’s Depressive Inventory, called the CDI-2. Our study demonstrated that the scores from the CDI-2 decreased, demonstrating less depressive symptomatology after the conclusion of the 8 week intervention. Our results were interpreted via our model of the mechanisms involved in influencing the success of ACT. Future research would include a greater sample size, a more relevant measure of depressive scores, and a consistent data collection environment. However our initial pilot study showed promising results for improving mental health in children with DS.
ContributorsErramuzpe, Sarah (Author) / Ringenbach, Shannon (Thesis director) / Yudell, Michael (Committee member) / Barrett, The Honors College (Contributor) / School of International Letters and Cultures (Contributor) / College of Health Solutions (Contributor)
Created2023-05
Description
Many children with disabilities need physical therapy treatment but it can be difficult to instruct patients with restricted or limited communication. Most exercise cards and depictions used in communicating instruction to pediatric special needs patients are not representative of children with disabilities. This project aimed to create inclusive physical therapy exercise cards depicting children with disabilities. The goal of these cards was to help communicate instructions and motivate children to perform their exercises in clinical settings. The exercise selection was based on observations from working with children with disabilities in a pediatric physical therapy clinic. As a result, photos of children with developmental disabilities were taken performing exercises and subsequently made into cards and provided to physical therapists (PT). The PT’s used the cards for at least a week and reported on their functionality. The feedback from PT’s regarding the use of exercise cards in therapy sessions was overwhelmingly positive. With the positive feedback from the PT’s, the cards will be published and donated to pediatric physical therapy clinics in Arizona.
ContributorsMack, Sarah (Author) / Hart, Teresa (Thesis director) / Broman, Tannah (Committee member) / Barrett, The Honors College (Contributor) / College of Health Solutions (Contributor)
Created2024-05
Description
Exercise is widely recognized for its myriad of health benefits, particularly in the realm of chronic disease prevention and treatment. Despite this knowledge, exercise remains significantly underutilized in the United States, with only a quarter of the population meeting the recommended physical activity guidelines set by the Department of Health and Human Services (Piercy et al., 2018). Recent research has spotlighted specific regions known as Blue Zones, where natural movement is incorporated into daily lives and populations are characterized by increased longevity and improved health outcomes, including lower rates of chronic diseases.
This study aimed to explore and compare exercise behaviors between the United States and the Ikaria Blue Zone in Greece, investigating their potential implications for a longer lifespan and enhanced health. Employing ethnographic methods, including immersive observation, semi-structured, qualitative interviews with locals, and the distribution of validated International Physical Activity Questionnaire (IPAQ) surveys, comprehensive data on exercise habits within the Ikarian population was collected in November 2023.
The findings from this study shed light on alternative forms of physical activity that have proven successful in populations with increased longevity. By identifying and understanding these practices, there is an opportunity to implement them in the United States, potentially contributing to improved exercise adherence and the prevention and treatment of chronic diseases. This research underscores the significance of cross-cultural insights in developing effective strategies to promote healthier lifestyles and enhance overall well-being.
ContributorsUnderhill, Jackson (Author) / Hrncir, Shawn (Thesis director) / Siegler, Jason (Committee member) / Barth, Christina (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor) / College of Health Solutions (Contributor)
Created2024-05
Description
Estimates indicate that in the United States 1 in 8 women will develop breast cancer in their lifetime. Improved cancer screenings, early detection, and targeted treatments have increased breast cancer survival rates. However, breast cancer patients treated with chemotherapy are at an increased risk for cardiovascular disease, functional impairments, and loss of cardiorespiratory fitness. These negative outcomes have implications for early morbidity and mortality. The purpose of this thesis was to test the hypothesis that high-intensity exercise preconditioning (exercise commenced prior to initiating chemotherapy and continued throughout treatment cycles) preserves health-related outcomes in breast cancer patients treated with anthracycline-containing chemotherapy. Here, we present a subset of preliminary data from an ongoing trial (NCT02842658) that is focused on VO2peak and skeletal muscle outcomes from the first 10 participants that have enrolled in the trial. Breast cancer patients (N=10; 50 ± 11 y; 168 ± 4 cm; 92 ± 37 kg; 32.3 ± 12.3 kg/m2) scheduled to receive anthracycline-containing chemotherapy were randomly assigned to one of two interventions: 1) exercise preconditioning, (3 days per week of supervised exercise throughout treatment) or 2) standard of care (attention-control). Pre-testing occurred 1-2 week prior to chemotherapy. The interventions were initiated 1 week prior to chemotherapy and continued throughout anthracycline treatment. Post-testing occurred 3-7 days following the last anthracycline treatment. VO2peak (L/min) was reduced by 16% in the control group (P < 0.05), whereas VO2peak was preserved in the exercise preconditioning group. Trends for greater preservation and/or improvement in the exercise preconditioning group were also observed for lean body mass and peak heart rate. Hand grip strength was not changed in either group (P > 0.05). Both groups demonstrated an increase in ultrasound-derived echogenicity measures of the vastus lateralis (P < 0.05), indicating changes in the composition of the skeletal muscle during treatment. These preliminary data highlight that exercise preconditioning may serve as a strategy to preserve cardiorespiratory fitness and perhaps lean mass during anthracycline treatment of breast cancer. There remains a need for larger, definitive clinical trials to identify strategies to prevent the array of chemotherapy-induced toxicities that are observed in breast cancer patients treated with anthracyclines.
ContributorsCasey, Kathleen (Author) / Angadi, Siddhartha (Thesis director) / Gaesser, Glenn (Committee member) / Dickinson, Jared (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Introduction: Diabetes Mellitus (DM) is a significant health problem in the United States, with over 20 million adults diagnosed with the condition. Type 2 Diabetes Mellitus, characterized by insulin resistance, in particular has been associated with various adverse conditions such as chronic kidney disease and peripheral artery disease. The presence of Type 2 Diabetes in an individual is also associated with various risk factors such as genetic markers and ethnicity. Native Americans, in particular, are more susceptible to Type 2 Diabetes Mellitus, with Native Americans having over two times the likelihood to present with Type 2 DM than non Hispanic whites. Of worry is the Pima Indian population in Arizona, which has the highest prevalence of Type 2 DM in the world. There have been many risk factors associated with the population such as genetic markers and lifestyle changes, but there has not been much research on the utilization of raw data to find the most pertinent factors for diabetes incidence.
Objective: There were three main objectives of the study. One objective was to elucidate potential new relationships via linear regression. Another objective was to determine which factors were indicative of Type 2 DM in the population. Finally, the last objective was to compare the incidence of Type 2 DM in the dataset to trends seen elsewhere.
Methods: The dataset was uploaded from an open source site with citation onto Python. The dataset, created in 1990, was composed of 768 female patients across 9 different attributes (Number of Pregnancies, Plasma Glucose Levels, Systolic Blood Pressure, Triceps Skin Thickness, Insulin Levels, BMI, Diabetes Pedigree Function, Age and Diabetes Presence (0 or 1)). The dataset was then cleaned using mean or median imputation. Post cleaning, linear regression was done to assess the relationships between certain factors in the population and assessed via the probability statistic for significance, with the exclusion of the Diabetes Pedigree Function and Diabetes Presence. Reverse stepwise logistic regression was used to determine the most pertinent factors for Type 2 DM via the Akaike Information Criterion and through the statistical significance in the model. Finally, data from the Center of Disease Control (CDC) Diabetes Surveillance was assessed for relationships with Female DM Percenatge in Pinal County through Obesity or through Physical Inactivity via simple logistic regression for statistical significance.
Results: The majority of the relationships found were statistically significant with each other. The most pertinent factors of Type 2 DM in the dataset were the number of pregnancies, the plasma glucose levels as well as the Blood Pressure. Via the USDS Data from the CDC, the relationships between Female DM Percentage and the obesity and inactivity percentages were statistically significant.
Conclusion: The trends found in the study matched the trends found in the literature. Per the results, recommendations for better diabetes control include more medical education as well as better blood sugar monitoring.With more analysis, there can be more done for checking other factors such as genetic factors and epidemiological analysis. In conclusion, the study accomplished its main objectives.
Objective: There were three main objectives of the study. One objective was to elucidate potential new relationships via linear regression. Another objective was to determine which factors were indicative of Type 2 DM in the population. Finally, the last objective was to compare the incidence of Type 2 DM in the dataset to trends seen elsewhere.
Methods: The dataset was uploaded from an open source site with citation onto Python. The dataset, created in 1990, was composed of 768 female patients across 9 different attributes (Number of Pregnancies, Plasma Glucose Levels, Systolic Blood Pressure, Triceps Skin Thickness, Insulin Levels, BMI, Diabetes Pedigree Function, Age and Diabetes Presence (0 or 1)). The dataset was then cleaned using mean or median imputation. Post cleaning, linear regression was done to assess the relationships between certain factors in the population and assessed via the probability statistic for significance, with the exclusion of the Diabetes Pedigree Function and Diabetes Presence. Reverse stepwise logistic regression was used to determine the most pertinent factors for Type 2 DM via the Akaike Information Criterion and through the statistical significance in the model. Finally, data from the Center of Disease Control (CDC) Diabetes Surveillance was assessed for relationships with Female DM Percenatge in Pinal County through Obesity or through Physical Inactivity via simple logistic regression for statistical significance.
Results: The majority of the relationships found were statistically significant with each other. The most pertinent factors of Type 2 DM in the dataset were the number of pregnancies, the plasma glucose levels as well as the Blood Pressure. Via the USDS Data from the CDC, the relationships between Female DM Percentage and the obesity and inactivity percentages were statistically significant.
Conclusion: The trends found in the study matched the trends found in the literature. Per the results, recommendations for better diabetes control include more medical education as well as better blood sugar monitoring.With more analysis, there can be more done for checking other factors such as genetic factors and epidemiological analysis. In conclusion, the study accomplished its main objectives.
ContributorsKondury, Kasyap Krishna (Author) / Scotch, Matthew (Thesis director) / Aliste, Marcela (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The aim of this paper is to investigate the B-casein fractions in Scandinavian and Icelandic milk for evidence to either support or refute the claim that the A1 variant of B-casein is diabetogenic in adolescent populations. Based on the theory that differences in milk protein composition explain a lower incidence of Type 1 Diabetes (T1D) in Iceland when compared to surrounding Nordic countries, an informative poster was created so that a more educated decision can be made by those wishing to take preventative measures against the incidence of the disease. This paper includes a basic background behind the epidemiology of T1D and the Nordic Nutrition Recommendations. Next, comparison between milk protein composition and consumption in Iceland against the other Nordic countries is performed through an in-depth literature review. The review was conducted using PubMed databases until December of 2018. Key findings of this investigation raise concerns regarding the decision between optimizing milk producing rates or breeding for milk devoid of diabetogenic proteins. The current literature on the impact of cattle genetics on the protein composition of milk sheds light on the safety of Icelandic dairy and the resulting health of their population. Icelandic dairy has been evidenced to contain lower levels of A1 b-casein and is considered less diabetogenic. For these reasons, this author would recommend the consumption of Icelandic dairy products over those from other regions.
ContributorsThunberg, Carly Marie (Author) / Morse, Lisa (Thesis director) / Grgich, Traci (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05